Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
11-1244304-C-T c.-50C>T 5_prime_UTR_premature_start_codon_gain MUC5B 1 27644 3.61742E-5 13822 0 1.3344E-4
11-1244338-C-T c.-16C>T 5_prime_UTR_premature_start_codon_gain MUC5B 2 33264 6.01251E-5 16632 0 7.22543E-4
11-1244339-G-A c.-15G>A 5_prime_UTR_premature_start_codon_gain MUC5B 1 31676 3.15696E-5 15838 0 3.9104E-5
11-1244364-C-T p.Pro4Leu missense MUC5B 1 39942 2.50363E-5 19971 0 3.19163E-5
11-1244368-C-T p.Ser5Ser synonymous MUC5B 5 39700 1.25945E-4 19850 2 0.00121674
11-1244369-G-A p.Ala6Thr missense MUC5B 2 40120 4.98504E-5 20060 0 9.57121E-5
11-1244370-C-T p.Ala6Val missense MUC5B 1 40596 2.4633E-5 20298 0 8.02826E-5
11-1244371-G-C p.Ala6Ala synonymous MUC5B 1 40880 2.44618E-5 20440 0 1.4459E-5
11-1244371-G-A p.Ala6Ala synonymous MUC5B 13 40880 3.18004E-4 20440 0 0.0037037
11-1244375-C-T p.Arg8Trp missense MUC5B 1 42488 2.35361E-5 21244 0 NA
11-1244382-T-A p.Leu10Gln missense MUC5B 1 44556 2.24437E-5 22278 0 NA
11-1244384-G-A p.Val11Met missense MUC5B 2 45040 4.4405E-5 22520 0 1.27423E-4
11-1244398-G-C p.Ala15Ala synonymous MUC5B 1 46910 2.13174E-5 23455 0 NA
11-1244398-G-T p.Ala15Ala synonymous MUC5B 1 46910 2.13174E-5 23455 0 7.32923E-5
11-1244398-G-A p.Ala15Ala synonymous MUC5B 1 46910 2.13174E-5 23455 0 3.51203E-5
11-1244408-G-A p.Val19Met missense MUC5B 13 47680 2.72651E-4 23840 0 7.92964E-4
11-1244408-G-C p.Val19Leu missense MUC5B 3 47682 6.29168E-5 23841 0 2.10096E-5
11-1244413-G-T p.Val20Val synonymous MUC5B 1 47940 2.08594E-5 23970 0 3.18796E-5
11-1244430-G-GC c.70+7_70+8insC splice_region MUC5B 1 47696 2.09661E-5 23848 0 3.18776E-5
11-1244431-C-A c.70+8C>A splice_region MUC5B 3 47486 6.31765E-5 23743 0 7.0372E-6
11-1246914-C-T p.Thr25Ile missense MUC5B 2 81308 2.45978E-5 40654 0 6.25E-4
11-1246915-C-T p.Thr25Thr synonymous MUC5B 1 81306 1.22992E-5 40653 0 4.36658E-6
11-1246928-G-C p.Glu30Gln missense MUC5B 1 81326 1.22962E-5 40663 0 NA
11-1246930-G-T p.Glu30Asp missense MUC5B 1 81336 1.22947E-5 40668 0 4.28633E-6
11-1246930-G-A p.Glu30Glu synonymous MUC5B 1 81336 1.22947E-5 40668 0 NA
11-1246932-C-T p.Pro31Leu missense MUC5B 3 81320 3.68913E-5 40660 0 5.05051E-4
11-1246941-A-G p.Glu34Gly missense MUC5B 19102 80554 0.237133 40277 2443 0.325059
11-1246950-G-C p.Gly37Ala missense MUC5B 1 81340 1.22941E-5 40670 0 4.26043E-6
11-1246951-G-A p.Gly37Gly synonymous MUC5B 3 81336 3.6884E-5 40668 0 1.31251E-5
11-1246952-C-T p.His38Tyr missense MUC5B 2 81328 2.45918E-5 40664 0 NA
11-1246958-A-G p.Met40Val missense MUC5B 2 81298 2.46009E-5 40649 0 NA
11-1246967-G-A p.Gly43Ser missense+splice_region MUC5B 1 81234 1.23101E-5 40617 0 4.05143E-5
11-1247441-C-T p.Pro45Leu missense MUC5B 1 81202 1.2315E-5 40601 0 9.98004E-5
11-1247442-G-A p.Pro45Pro synonymous MUC5B 2 81196 2.46318E-5 40598 0 3.18613E-5
11-1247444-C-T p.Thr46Met missense MUC5B 1 81202 1.2315E-5 40601 0 3.18613E-5
11-1247447-C-T p.Ser47Phe missense MUC5B 1 81226 1.23113E-5 40613 0 3.18613E-5
11-1247450-C-T p.Ser48Leu missense MUC5B 5 81218 6.15627E-5 40609 1 6.37349E-5
11-1247458-C-T p.Arg51Trp missense MUC5B 7577 81114 0.0934117 40557 463 0.137919
11-1247459-G-A p.Arg51Gln missense MUC5B 7 81202 8.62048E-5 40601 0 0.00125
11-1247462-G-A p.Arg52His missense MUC5B 3 81210 3.69413E-5 40605 0 1.40095E-4
11-1247462-G-C p.Arg52Pro missense MUC5B 1 81210 1.23138E-5 40605 0 NA
11-1247463-C-T p.Arg52Arg synonymous MUC5B 1 81212 1.23135E-5 40606 0 3.18654E-5
11-1247464-G-T p.Val53Leu missense MUC5B 1 81208 1.23141E-5 40604 0 NA
11-1247464-G-A p.Val53Met missense MUC5B 4 81208 4.92562E-5 40604 0 9.56023E-5
11-1247481-C-T p.Pro58Pro synonymous MUC5B 2 81204 2.46293E-5 40602 0 3.18613E-5
11-1247482-G-A p.Val59Ile missense MUC5B 2 81196 2.46318E-5 40598 0 4.63306E-5
11-1247495-C-T p.Pro63Leu missense MUC5B 1 81150 1.23229E-5 40575 0 NA
11-1247506-C-T p.Pro67Ser missense+splice_region MUC5B 177 81112 0.00218217 40556 1 0.00484231
11-1247837-C-G c.200-8C>G splice_region MUC5B 6 80182 7.48298E-5 40091 0 9.56572E-5
11-1247854-C-T p.Pro70Leu missense MUC5B 4 80154 4.99039E-5 40077 0 1.59408E-4
11-1247855-G-A p.Pro70Pro synonymous MUC5B 11 80122 1.37291E-4 40061 0 2.55086E-4
11-1247855-G-T p.Pro70Pro synonymous MUC5B 1 80122 1.2481E-5 40061 0 6.37714E-5
11-1247857-C-T p.Ala71Val missense MUC5B 2 80108 2.49663E-5 40054 0 3.31436E-5
11-1247858-G-A p.Ala71Ala synonymous MUC5B 5 80166 6.23706E-5 40083 0 2.29848E-5
11-1247867-G-A p.Gly74Gly synonymous MUC5B 2 80398 2.48762E-5 40199 0 1.08632E-5
11-1247868-C-T p.Arg75Trp missense MUC5B 6 80404 7.46232E-5 40202 0 0.0025
11-1247869-G-A p.Arg75Gln missense MUC5B 1 80392 1.2439E-5 40196 0 1.23334E-5
11-1247905-C-T p.Thr87Ile missense MUC5B 4 81214 4.92526E-5 40607 0 6.37349E-5
11-1247909-C-T p.Phe88Phe synonymous MUC5B 3 81266 3.69158E-5 40633 0 9.56023E-5
11-1247910-G-A p.Asp89Asn missense MUC5B 1 81306 1.22992E-5 40653 0 1.84744E-5
11-1247912-C-T p.Asp89Asp synonymous MUC5B 1 81312 1.22983E-5 40656 0 3.18695E-5
11-1247913-G-A p.Gly90Ser missense MUC5B 3 81370 3.68686E-5 40685 0 2.83596E-5
11-1247915-C-T p.Gly90Gly synonymous MUC5B 2 81352 2.45845E-5 40676 0 9.56023E-5
11-1247919-G-C p.Val92Leu missense MUC5B 1 81530 1.22654E-5 40765 0 NA
11-1247919-G-A p.Val92Ile missense MUC5B 1 81530 1.22654E-5 40765 0 4.04845E-6
11-1247924-C-T p.Phe93Phe synonymous MUC5B 1 81638 1.22492E-5 40819 0 4.04403E-6
11-1247925-C-T p.Arg94Cys missense MUC5B 1 81638 1.22492E-5 40819 0 3.18654E-5
11-1247932-C-T p.Pro96Leu missense MUC5B 1 81790 1.22264E-5 40895 0 NA
11-1247948-C-T p.Tyr101Tyr synonymous MUC5B 1 81812 1.22231E-5 40906 0 6.37308E-5
11-1247960-G-C p.Glu105Asp missense MUC5B 6 81702 7.34376E-5 40851 0 3.18471E-5
11-1247962-A-G p.His106Arg missense MUC5B 1 81662 1.22456E-5 40831 0 8.60822E-6
11-1247967-C-T p.Arg108Cys missense MUC5B 1 81554 1.22618E-5 40777 0 3.18492E-5
11-1247968-G-A p.Arg108His missense MUC5B 4 81480 4.90918E-5 40740 0 4.03887E-5
11-1247969-C-T p.Arg108Arg synonymous MUC5B 356 81462 0.00437014 40731 1 0.00745365
11-1247972-C-T p.Ala109Ala synonymous MUC5B 2 81376 2.45773E-5 40688 0 8.88652E-5
11-1247973-G-A p.Ala110Thr missense MUC5B 1 81300 1.23001E-5 40650 0 4.29192E-5
11-1247974-C-G p.Ala110Gly missense MUC5B 1 81280 1.23031E-5 40640 0 NA
11-1247990-C-T p.Asn115Asn synonymous MUC5B 7 80556 8.68961E-5 40278 0 1.59246E-4
11-1247991-G-A p.Val116Ile missense MUC5B 1 80452 1.24298E-5 40226 0 3.18492E-5
11-1248001-G-A p.Arg119His missense MUC5B 130 79664 0.00163185 39832 0 7.52975E-4
11-1248016-G-A p.Gly124Asp missense MUC5B 1 78628 1.27181E-5 39314 0 NA
11-1248036-C-T p.Arg131Cys missense MUC5B 3 77090 3.89156E-5 38545 0 1.62742E-5
11-1248057-G-A p.Gly138Arg missense MUC5B 1 75452 1.32535E-5 37726 0 NA
11-1248066-C-A p.Leu141Met missense MUC5B 1 74468 1.34286E-5 37234 0 NA
11-1248073-C-T p.Ala143Val missense MUC5B 2 73070 2.7371E-5 36535 0 5.04541E-4
11-1248073-C-G p.Ala143Gly missense MUC5B 3 73070 4.10565E-5 36535 0 1.24346E-5
11-1248074-G-A p.Ala143Ala synonymous MUC5B 2 72986 2.74025E-5 36493 0 1.32715E-4
11-1248074-G-T p.Ala143Ala synonymous MUC5B 4 72986 5.4805E-5 36493 0 5.04541E-4
11-1248080-C-T p.Asn145Asn synonymous MUC5B 7 72164 9.70013E-5 36082 0 6.37918E-5
11-1248081-G-A p.Gly146Ser missense MUC5B 11 71702 1.53413E-4 35851 0 4.16913E-5
11-1248084-T-C p.Ser147Pro missense MUC5B 2 71372 2.80222E-5 35686 0 1.25498E-5
11-1248086-C-T p.Ser147Ser synonymous MUC5B 3 71000 4.22535E-5 35500 0 0.00125
11-1248087-G-A p.Val148Ile missense MUC5B 700 70452 0.00993584 35226 6 0.0201816
11-1248093-A-C p.Ile150Leu missense MUC5B 3 70058 4.28217E-5 35029 0 1.81449E-5
11-1248095-C-T p.Ile150Ile synonymous MUC5B 1 69870 1.43123E-5 34935 0 2.64391E-4
11-1248095-C-A p.Ile150Ile synonymous MUC5B 1 69870 1.43123E-5 34935 0 4.20723E-6
11-1248106-G-A p.Arg154Gln missense+splice_region MUC5B 1 67364 1.48447E-5 33682 0 4.27069E-6
11-1248113-C-T c.461+7C>T splice_region MUC5B 11 65586 1.67719E-4 32793 0 1.92025E-4
11-1248114-G-A c.461+8G>A splice_region MUC5B 3 65742 4.56329E-5 32871 0 9.5358E-6
11-1248256-C-T c.462-5C>T splice_region MUC5B 6 78996 7.59532E-5 39498 0 6.43556E-5
11-1248257-G-A c.462-4G>A splice_region MUC5B 1 79090 1.26438E-5 39545 0 5.28608E-5
11-1248257-G-T c.462-4G>T splice_region MUC5B 1 79090 1.26438E-5 39545 0 3.18735E-5
11-1248280-C-T p.Arg161Cys missense MUC5B 1 80708 1.23903E-5 40354 0 2.03684E-5
11-1248281-G-A p.Arg161His missense MUC5B 4 80776 4.95197E-5 40388 0 6.25E-4
11-1248283-A-G p.Thr162Ala missense MUC5B 1 80888 1.23628E-5 40444 0 NA
11-1248284-C-A p.Thr162Asn missense MUC5B 1 80928 1.23567E-5 40464 0 2.91121E-4
11-1248286-G-A p.Gly163Ser missense MUC5B 2 81026 2.46834E-5 40513 0 6.37471E-5
11-1248289-C-T p.Leu164Phe missense MUC5B 5 81126 6.16325E-5 40563 0 5.05051E-4
11-1248291-C-T p.Leu164Leu synonymous MUC5B 70 81170 8.62388E-4 40585 0 0.00152964
11-1248295-G-T p.Val166Leu missense MUC5B 1 81224 1.23116E-5 40612 0 3.18654E-5
11-1248305-G-A p.Ser169Asn missense MUC5B 2 81420 2.4564E-5 40710 0 2.62509E-5
11-1248306-C-T p.Ser169Ser synonymous MUC5B 3 81410 3.68505E-5 40705 0 3.18756E-5
11-1248307-G-A p.Gly170Arg missense MUC5B 1 81442 1.22787E-5 40721 0 8.73027E-5
11-1248325-A-G p.Ser176Gly missense MUC5B 1 81638 1.22492E-5 40819 0 NA
11-1248357-C-T p.Asn186Asn synonymous MUC5B 1 81688 1.22417E-5 40844 0 9.55962E-5
11-1248358-G-T p.Gly187* stop_gained MUC5B 1 81686 1.2242E-5 40843 0 4.05098E-6
11-1248532-T-C c.577-6T>C splice_region MUC5B 1 82088 1.2182E-5 41044 0 NA
11-1248541-G-C p.Glu194Gln missense MUC5B 1 82126 1.21764E-5 41063 0 NA
11-1248542-A-G p.Glu194Gly missense MUC5B 1 82132 1.21755E-5 41066 0 9.0519E-6
11-1248544-C-G p.Leu195Val missense MUC5B 1 82142 1.2174E-5 41071 0 NA
11-1248551-C-A p.Pro197His missense MUC5B 1 82186 1.21675E-5 41093 0 NA
11-1248555-A-G p.Lys198Lys synonymous MUC5B 1 82210 1.2164E-5 41105 0 8.08029E-6
11-1248558-C-T p.Tyr199Tyr synonymous MUC5B 7 82216 8.51416E-5 41108 0 9.55597E-5
11-1248559-G-A p.Ala200Thr missense MUC5B 4 82220 4.865E-5 41110 0 6.46642E-5
11-1248563-A-G p.Asn201Ser missense MUC5B 1 82218 1.21628E-5 41109 0 4.03903E-6
11-1248567-G-A p.Gln202Gln synonymous MUC5B 2 82236 2.43202E-5 41118 0 NA
11-1248594-C-T p.Asn211Asn synonymous MUC5B 8 82254 9.72597E-5 41127 0 9.55657E-5
11-1248595-G-A p.Gly212Ser missense MUC5B 4 82246 4.86346E-5 41123 0 3.6568E-4
11-1248597-C-T p.Gly212Gly synonymous MUC5B 1 82238 1.21598E-5 41119 0 3.18552E-5
11-1248598-C-T p.Leu213Phe missense MUC5B 2 82242 2.43185E-5 41121 0 NA
11-1248602-C-T p.Pro214Leu missense MUC5B 1 82226 1.21616E-5 41113 0 1.27421E-4
11-1248603-G-A p.Pro214Pro synonymous MUC5B 4 82198 4.8663E-5 41099 0 3.97567E-5
11-1248612-C-T p.Asn217Asn synonymous MUC5B 11 82166 1.33875E-4 41083 0 1.13334E-4
11-1248620-A-G p.Tyr220Cys missense MUC5B 7 82148 8.52121E-5 41074 0 3.18634E-4
11-1248625-C-T p.His222Tyr missense MUC5B 1 82126 1.21764E-5 41063 0 8.23683E-6
11-1248898-C-T c.668-7C>T splice_region MUC5B 3 66298 4.52502E-5 33149 0 1.01071E-4
11-1248899-C-T c.668-6C>T splice_region MUC5B 2 66142 3.0238E-5 33071 0 9.56084E-5
11-1248900-G-A c.668-5G>A splice_region MUC5B 5 66010 7.57461E-5 33005 0 2.01207E-4
11-1248906-C-T p.Asn223Asn splice_region+synonymous MUC5B 14 65510 2.13708E-4 32755 0 3.96904E-4
11-1248907-G-A p.Ala224Thr missense+splice_region MUC5B 3 65416 4.58603E-5 32708 0 5.15464E-4
11-1248920-C-T p.Pro228Leu missense MUC5B 6 64594 9.28879E-5 32297 0 2.55021E-4
11-1248921-G-A p.Pro228Pro synonymous MUC5B 1 64476 1.55096E-5 32238 0 6.25E-4
11-1248922-C-T p.Leu229Phe missense MUC5B 1 64450 1.55159E-5 32225 0 NA
11-1248924-C-T p.Leu229Leu synonymous MUC5B 1 64392 1.55299E-5 32196 0 0.00125
11-1248930-T-A p.Phe231Leu missense MUC5B 1 64070 1.56079E-5 32035 0 NA
11-1248931-G-A p.Gly232Arg missense MUC5B 1 64056 1.56113E-5 32028 0 NA
11-1248935-A-C p.Asn233Thr missense MUC5B 1 63880 1.56544E-5 31940 0 6.04939E-6
11-1248936-C-A p.Asn233Lys missense MUC5B 1 63880 1.56544E-5 31940 0 4.78606E-5
11-1248939-G-A p.Leu234Leu synonymous MUC5B 4 63792 6.27038E-5 31896 0 3.63073E-5
11-1248949-G-C p.Asp238His missense MUC5B 1 63570 1.57307E-5 31785 0 NA
11-1248957-C-A p.Pro240Pro synonymous MUC5B 1 63362 1.57823E-5 31681 0 NA
11-1248960-G-A p.Thr241Thr synonymous MUC5B 4310 63122 0.0682805 31561 169 0.09875
11-1248963-G-A p.Glu242Glu synonymous MUC5B 1 63156 1.58338E-5 31578 0 6.17414E-6
11-1248971-C-T p.Pro245Leu missense MUC5B 2 62940 3.17763E-5 31470 0 9.993E-5
11-1248972-G-A p.Pro245Pro synonymous MUC5B 2 62920 3.17864E-5 31460 0 1.50376E-4
11-1248977-C-T p.Pro247Leu missense MUC5B 2 62814 3.184E-5 31407 0 3.78879E-5
11-1248978-G-A p.Pro247Pro synonymous MUC5B 3 62764 4.77981E-5 31382 0 5.18672E-4
11-1248989-C-G p.Pro251Arg missense MUC5B 7 62498 1.12004E-4 31249 0 NA
11-1248989-C-T p.Pro251Leu missense MUC5B 3 62498 4.80015E-5 31249 0 0.00260688
11-1248990-G-A p.Pro251Pro synonymous MUC5B 2 62466 3.20174E-5 31233 0 1.07193E-4
11-1248993-C-T p.Ala252Ala synonymous MUC5B 2 62356 3.20739E-5 31178 0 2.58548E-5
11-1248994-G-A p.Gly253Ser missense MUC5B 801 62334 0.0128501 31167 25 0.0241797
11-1249004-C-T p.Thr256Met missense MUC5B 2 62098 3.22072E-5 31049 1 6.56538E-6
11-1249005-G-A p.Thr256Thr synonymous MUC5B 1 62084 1.61072E-5 31042 0 6.25E-4
11-1249016-G-A c.774+5G>A splice_region MUC5B 1 61522 1.62543E-5 30761 0 6.69559E-6
11-1249791-C-T c.775-3C>T splice_region MUC5B 1 44380 2.25327E-5 22190 0 NA
11-1249805-C-T p.Cys262Cys synonymous MUC5B 1 46030 2.1725E-5 23015 0 3.04655E-5
11-1249810-G-A p.Arg264His missense MUC5B 2 46586 4.29314E-5 23293 0 1.00725E-4
11-1249815-C-T p.Leu266Leu synonymous MUC5B 2 47542 4.20681E-5 23771 0 NA
11-1249826-G-A p.Pro269Pro synonymous MUC5B 22 49234 4.46846E-4 24617 0 0.00130548
11-1249834-C-T p.Ala272Val missense MUC5B 5 50602 9.88103E-5 25301 0 0.00181878
11-1249835-G-A p.Ala272Ala synonymous MUC5B 5 50688 9.86427E-5 25344 0 1.33901E-4
11-1249836-G-A p.Glu273Lys missense MUC5B 1 51000 1.96078E-5 25500 0 NA
11-1249844-C-T p.His275His synonymous MUC5B 2 52744 3.7919E-5 26372 0 0.00126904
11-1249845-G-A p.Ala276Thr missense MUC5B 3 52770 5.68505E-5 26385 0 6.38121E-5
11-1249853-G-A p.Val278Val synonymous MUC5B 2 54388 3.67728E-5 27194 0 2.37229E-4
11-1249862-T-C p.Thr281Thr synonymous MUC5B 1 55676 1.79611E-5 27838 0 NA
11-1249864-C-A p.Ala282Glu missense MUC5B 12 55886 2.14723E-4 27943 0 2.42704E-4
11-1249864-C-T p.Ala282Val missense MUC5B 3 55886 5.36807E-5 27943 0 3.19163E-5
11-1249873-C-T p.Ala285Val missense MUC5B 19 57508 3.30389E-4 28754 0 0.0012987
11-1249874-C-T p.Ala285Ala synonymous MUC5B 40 57690 6.93361E-4 28845 0 0.0015952
11-1249877-C-A p.Ala286Ala synonymous MUC5B 2 58602 3.41285E-5 29301 0 1.53681E-4
11-1249880-C-T p.Cys287Cys synonymous MUC5B 2 58846 3.3987E-5 29423 0 2.9335E-5
11-1249881-G-T p.Ala288Ser missense MUC5B 1 58974 1.69566E-5 29487 0 7.32858E-6
11-1249881-G-A p.Ala288Thr missense MUC5B 4 58976 6.78242E-5 29488 0 7.67931E-5
11-1249893-T-C p.Cys292Arg missense MUC5B 2 61174 3.26936E-5 30587 0 2.92312E-5
11-1249896-C-T p.Arg293Cys missense MUC5B 3 61332 4.89141E-5 30666 0 3.18979E-5
11-1249897-G-A p.Arg293His missense MUC5B 1 61292 1.63153E-5 30646 0 7.31037E-6
11-1249912-C-T p.Pro298Leu missense MUC5B 1 63118 1.58433E-5 31559 0 6.37714E-5
11-1249913-G-A p.Pro298Pro synonymous MUC5B 5 63160 7.9164E-5 31580 0 6.37552E-5
11-1249917-G-A p.Ala300Thr missense MUC5B 1 63732 1.56907E-5 31866 0 NA
11-1249921-C-G p.Thr301Ser missense MUC5B 2 64284 3.11119E-5 32142 0 NA
11-1249939-G-A p.Arg307His missense MUC5B 5 64170 7.7918E-5 32085 0 5.9952E-4
11-1249946-C-T p.Cys309Cys synonymous MUC5B 2 63798 3.13489E-5 31899 0 1.72861E-4
11-1249947-G-A p.Ala310Thr missense MUC5B 2 63782 3.13568E-5 31891 0 6.37877E-5
11-1249952-C-T p.His311His synonymous MUC5B 389 63614 0.00611501 31807 0 0.00673132
11-1249952-C-G p.His311Gln missense MUC5B 1 63648 1.57114E-5 31824 0 NA
11-1249952-C-A p.His311Gln missense MUC5B 1 63648 1.57114E-5 31824 0 NA
11-1249953-G-A p.Ala312Thr missense MUC5B 8 63496 1.25992E-4 31748 0 3.71157E-5
11-1249955-G-A p.Ala312Ala synonymous MUC5B 2 63402 3.15447E-5 31701 0 6.33714E-4
11-1249955-G-C p.Ala312Ala synonymous MUC5B 1 63402 1.57724E-5 31701 0 NA
11-1249960-G-T p.Gly314Val missense MUC5B 2 63104 3.16937E-5 31552 0 7.51213E-6
11-1249966-C-T p.Pro316Leu missense MUC5B 3 62532 4.79754E-5 31266 0 1.10889E-4
11-1249967-G-A p.Pro316Pro synonymous MUC5B 3 62438 4.80477E-5 31219 0 1.12057E-4
11-1249968-C-T p.Arg317Trp missense MUC5B 1 62364 1.60349E-5 31182 0 7.57564E-6
11-1249969-G-A p.Arg317Gln missense MUC5B 2 62600 3.19489E-5 31300 0 3.04405E-5
11-1249995-C-T p.Pro326Ser missense+splice_region MUC5B 13 58202 2.2336E-4 29101 0 7.67116E-4
11-1250395-C-T c.977-5C>T splice_region MUC5B 320 79992 0.0040004 39996 0 0.00390779
11-1250402-C-T p.Arg327Trp missense+splice_region MUC5B 1 80190 1.24704E-5 40095 0 8.18956E-5
11-1250403-G-A p.Arg327Gln missense MUC5B 1 80206 1.24679E-5 40103 0 4.52129E-6
11-1250407-C-T p.Thr328Thr synonymous MUC5B 1 80408 1.24366E-5 40204 0 4.47331E-6
11-1250434-G-A p.Glu337Glu synonymous MUC5B 1 80970 1.23503E-5 40485 0 4.3496E-6
11-1250445-C-A p.Pro341His missense MUC5B 1 81022 1.23423E-5 40511 0 1.30924E-5
11-1250446-C-T p.Pro341Pro synonymous MUC5B 1 81052 1.23378E-5 40526 0 NA
11-1250451-C-T p.Thr343Met missense MUC5B 2 81038 2.46798E-5 40519 0 6.38651E-5
11-1250452-G-A p.Thr343Thr synonymous MUC5B 1 81038 1.23399E-5 40519 0 1.31524E-5
11-1250475-G-A p.Arg351His missense MUC5B 1 80988 1.23475E-5 40494 0 9.5816E-5
11-1250476-C-T p.Arg351Arg synonymous MUC5B 10 80980 1.23487E-4 40490 0 1.56955E-4
11-1250477-G-A p.Ala352Thr missense MUC5B 7 80966 8.6456E-5 40483 0 6.25E-4
11-1250479-G-A p.Ala352Ala synonymous MUC5B 4 80956 4.94096E-5 40478 0 6.38488E-5
11-1250482-G-A p.Gln353Gln synonymous MUC5B 2 80992 2.46938E-5 40496 0 4.41735E-5
11-1250488-C-T p.Cys355Cys synonymous MUC5B 28721 80254 0.357876 40127 5365 0.439547
11-1250494-C-T p.Asp357Asp synonymous MUC5B 4 80846 4.94768E-5 40423 0 NA
11-1250506-C-T p.Asp361Asp synonymous MUC5B 7 80598 8.68508E-5 40299 0 8.93895E-5
11-1250522-C-G p.Pro367Ala missense MUC5B 1 80152 1.24763E-5 40076 0 NA
11-1250523-C-T p.Pro367Leu missense+splice_region MUC5B 1 80158 1.24754E-5 40079 0 1.08419E-4
11-1250529-G-A p.Arg369Lys missense MUC5B 3 79736 3.76242E-5 39868 0 1.16414E-4
11-1250532-C-G p.Ser370Cys missense+splice_region MUC5B 1 79540 1.25723E-5 39770 0 NA
11-1250539-G-A c.1111+5G>A splice_region MUC5B 3 79006 3.79718E-5 39503 0 NA
11-1250542-C-T c.1111+8C>T splice_region MUC5B 1 78944 1.26672E-5 39472 0 3.63702E-5
11-1250920-G-A p.Cys371Tyr missense+splice_region MUC5B 1 55142 1.8135E-5 27571 0 NA
11-1250924-G-T p.Thr372Thr synonymous MUC5B 3 55232 5.43163E-5 27616 0 4.03031E-5
11-1250924-G-A p.Thr372Thr synonymous MUC5B 3 55232 5.43163E-5 27616 0 1.27665E-4
11-1250944-A-G p.His379Arg missense MUC5B 1 57240 1.74703E-5 28620 0 NA
11-1250951-C-T p.Gly381Gly synonymous MUC5B 3 58016 5.17099E-5 29008 0 6.38407E-5
11-1250961-C-T p.Leu385Phe missense MUC5B 3 58932 5.09061E-5 29466 0 0.00125
11-1250963-C-T p.Leu385Leu synonymous MUC5B 1 58962 1.69601E-5 29481 0 5.04541E-4
11-1250984-C-T p.His392His synonymous MUC5B 4 60280 6.6357E-5 30140 0 1.35108E-5
11-1250987-C-T p.Gly393Gly synonymous MUC5B 1 60262 1.65942E-5 30131 0 6.25E-4
11-1250988-G-A p.Gly394Ser missense MUC5B 2 60518 3.3048E-5 30259 0 0.0020202
11-1250992-G-A p.Arg395His missense MUC5B 1 61208 1.63377E-5 30604 0 7.68905E-5
11-1250995-C-T p.Thr396Ile missense MUC5B 1 62024 1.61228E-5 31012 0 NA
11-1251004-C-T p.Pro399Leu missense MUC5B 2 62760 3.18674E-5 31380 0 1.31842E-4
11-1251004-C-G p.Pro399Arg missense MUC5B 1 62760 1.59337E-5 31380 0 NA
11-1251019-A-G p.Asn404Ser missense MUC5B 1 63262 1.58073E-5 31631 0 NA
11-1251025-C-T p.Thr406Ile missense MUC5B 2 63594 3.14495E-5 31797 0 5.8266E-5
11-1251032-C-T p.Ser408Ser synonymous MUC5B 1 63504 1.5747E-5 31752 0 7.97862E-5
11-1251227-C-G c.1230-8C>G splice_region MUC5B 1 79606 1.25619E-5 39803 0 9.2835E-6
11-1251228-TC-T c.1230-6delC splice_region MUC5B 2 79554 2.51402E-5 39777 0 NA
11-1251232-C-T c.1230-3C>T splice_region MUC5B 1 79736 1.25414E-5 39868 0 5.51572E-5
11-1251237-C-T p.Thr411Ile missense+splice_region MUC5B 1 79944 1.25088E-5 39972 0 3.19061E-5
11-1251244-C-T p.Ser413Ser synonymous MUC5B 3 80008 3.74963E-5 40004 0 1.811E-5
11-1251245-G-A p.Gly414Arg missense MUC5B 1 80014 1.24978E-5 40007 0 3.19183E-5
11-1251274-G-A p.Pro423Pro synonymous MUC5B 1 81168 1.23201E-5 40584 0 5.03525E-4
11-1251275-T-C p.Cys424Arg missense MUC5B 1 81234 1.23101E-5 40617 0 NA
11-1251280-T-G p.Pro425Pro synonymous MUC5B 1 81348 1.22929E-5 40674 0 1.22083E-5
11-1251282-G-C p.Gly426Ala missense MUC5B 1 81368 1.22898E-5 40684 0 8.52355E-6
11-1251301-C-T p.Gly432Gly synonymous MUC5B 1738 81436 0.0213419 40718 25 0.0303659
11-1251302-G-A p.Gly433Arg missense MUC5B 1 81508 1.22687E-5 40754 0 6.25E-4
11-1251303-G-A p.Gly433Glu missense MUC5B 1 81526 1.2266E-5 40763 0 3.19061E-5
11-1251311-A-G p.Ile436Val missense MUC5B 1 81602 1.22546E-5 40801 0 4.03301E-6
11-1251337-C-T p.Tyr444Tyr synonymous MUC5B 1 81640 1.22489E-5 40820 0 5.03525E-4
11-1251344-C-T p.His447Tyr missense MUC5B 7 81652 8.57297E-5 40826 0 1.61909E-5
11-1251357-G-C p.Ser451Thr missense MUC5B 4 81426 4.91244E-5 40713 0 4.09759E-6
11-1251357-G-A p.Ser451Asn missense MUC5B 2 81426 2.45622E-5 40713 0 4.09759E-6
11-1251361-C-T p.Tyr452Tyr synonymous MUC5B 4 81352 4.9169E-5 40676 0 3.18756E-5
11-1251368-T-A p.Ser455Thr missense MUC5B 43 81126 5.3004E-4 40563 0 0.00121135
11-1251381-C-T c.1368+8C>T splice_region MUC5B 1 80382 1.24406E-5 40191 0 4.49035E-6
11-1251715-C-G c.1369-5C>G splice_region MUC5B 1 81338 1.22944E-5 40669 0 NA
11-1251717-C-T c.1369-3C>T splice_region MUC5B 13 81354 1.59795E-4 40677 0 3.18573E-4
11-1251728-C-T p.Ala459Ala synonymous MUC5B 5 81396 6.14281E-5 40698 0 0.0010101
11-1251729-G-A p.Asp460Asn missense MUC5B 2 81400 2.457E-5 40700 0 5.31194E-5
11-1251743-C-T p.Thr464Thr synonymous MUC5B 1 81524 1.22663E-5 40762 0 1.11804E-5
11-1251743-C-G p.Thr464Thr synonymous MUC5B 1 81524 1.22663E-5 40762 0 NA
11-1251744-G-A p.Val465Met missense MUC5B 1 81540 1.22639E-5 40770 0 0.00201816
11-1251744-G-T p.Val465Leu missense MUC5B 2 81540 2.45278E-5 40770 0 NA
11-1251751-C-G p.Ala467Gly missense MUC5B 1 81538 1.22642E-5 40769 0 NA
11-1251756-C-T p.Leu469Leu synonymous MUC5B 10 81538 1.22642E-4 40769 0 1.12742E-4
11-1251759-C-T p.Arg470Trp missense MUC5B 2 81528 2.45314E-5 40764 0 3.03933E-5
11-1251760-G-A p.Arg470Gln missense MUC5B 2 81542 2.45272E-5 40771 0 4.01695E-5
11-1251766-G-A p.Cys472Tyr missense MUC5B 1 81554 1.22618E-5 40777 0 4.07017E-6
11-1251767-C-T p.Cys472Cys synonymous MUC5B 1 81562 1.22606E-5 40781 0 0.00302725
11-1251768-G-A p.Gly473Ser missense MUC5B 1 81566 1.226E-5 40783 0 3.66444E-5
11-1251772-T-G p.Leu474Arg missense MUC5B 1 81588 1.22567E-5 40794 0 NA
11-1251775-C-T p.Thr475Met missense MUC5B 55 81604 6.73987E-4 40802 0 0.00403633
11-1251776-G-A p.Thr475Thr synonymous MUC5B 39 81612 4.77871E-4 40806 0 0.0025
11-1251777-GACA-G p.Asn477del conservative_inframe_deletion MUC5B 3 81604 3.67629E-5 40802 0 6.36983E-5
11-1251783-G-A p.Glu478Lys missense MUC5B 2 81618 2.45044E-5 40809 0 NA
11-1251799-C-T p.Ala483Val missense MUC5B 10 81588 1.22567E-4 40794 0 0.0025227
11-1251800-G-A p.Ala483Ala synonymous MUC5B 108 81586 0.00132376 40793 0 0.00286716
11-1251805-C-T p.Thr485Met missense MUC5B 12 81496 1.47246E-4 40748 0 6.25E-4
11-1251806-G-C p.Thr485Thr synonymous MUC5B 1 81428 1.22808E-5 40714 0 NA
11-1251807-C-T p.Leu486Phe missense MUC5B 1 81426 1.22811E-5 40713 0 NA
11-1251809-C-T p.Leu486Leu synonymous MUC5B 1 81406 1.22841E-5 40703 0 NA
11-1251816-G-A p.Asp489Asn missense MUC5B 7 81348 8.60501E-5 40674 0 1.59307E-4
11-1251818-C-T p.Asp489Asp synonymous MUC5B 4 81288 4.92078E-5 40644 0 1.59347E-4
11-1251819-G-A p.Gly490Ser missense MUC5B 45 81212 5.54105E-4 40606 0 0.00151668
11-1251822-G-C p.Gly491Arg missense MUC5B 6 81212 7.38807E-5 40606 0 1.24179E-5
11-1251822-G-A p.Gly491Arg missense MUC5B 7 81212 8.61942E-5 40606 0 2.54972E-4
11-1251829-C-T p.Thr493Met missense+splice_region MUC5B 1 81090 1.2332E-5 40545 0 5.04541E-4
11-1251830-G-A p.Thr493Thr splice_region+synonymous MUC5B 4 81080 4.9334E-5 40540 0 3.18634E-5
11-1252161-C-T c.1480-5C>T splice_region MUC5B 2 79414 2.51845E-5 39707 0 2.96124E-5
11-1252162-G-A c.1480-4G>A splice_region MUC5B 3 79392 3.77872E-5 39696 0 1.3395E-4
11-1252172-C-T p.Arg496Trp missense MUC5B 1 79890 1.25172E-5 39945 0 0.00257202
11-1252173-G-A p.Arg496Gln missense MUC5B 5 79894 6.25829E-5 39947 0 2.94239E-5
11-1252182-C-T p.Ala499Val missense MUC5B 1 80132 1.24794E-5 40066 0 5.3723E-5
11-1252186-C-T p.Asp500Asp synonymous MUC5B 3 80212 3.74009E-5 40106 0 1.01958E-4
11-1252187-G-A p.Gly501Ser missense MUC5B 7 80232 8.7247E-5 40116 0 1.75924E-4
11-1252189-C-T p.Gly501Gly synonymous MUC5B 7 80220 8.726E-5 40110 0 1.59561E-4
11-1252190-G-A p.Gly502Ser missense MUC5B 1 80282 1.24561E-5 40141 0 1.21625E-4
11-1252192-C-T p.Gly502Gly synonymous MUC5B 140 80272 0.00174407 40136 1 0.00342433
11-1252193-G-A p.Val503Met missense MUC5B 2 80312 2.49029E-5 40156 0 3.19E-5
11-1252208-A-G p.Ile508Val missense MUC5B 1 80504 1.24217E-5 40252 0 NA
11-1252215-C-T p.Thr510Met missense MUC5B 76 80440 9.44804E-4 40220 0 0.00462487
11-1252215-C-A p.Thr510Lys missense MUC5B 2 80444 2.4862E-5 40222 0 3.18756E-5
11-1252220-C-T p.Leu512Leu synonymous MUC5B 195 80354 0.00242676 40177 1 0.00455733
11-1252223-C-A p.Pro513Thr missense MUC5B 1 80322 1.24499E-5 40161 0 4.58652E-5
11-1252227-T-A p.Leu514Gln missense MUC5B 1 80272 1.24576E-5 40136 0 NA
11-1252231-G-A p.Ser515Ser synonymous MUC5B 3 80180 3.74158E-5 40090 0 7.04689E-5
11-1252647-C-T c.1550-6C>T splice_region MUC5B 2 81232 2.46208E-5 40616 0 1.78063E-5
11-1252648-G-A c.1550-5G>A splice_region MUC5B 1145 81158 0.0141083 40579 12 0.0206712
11-1252649-G-A c.1550-4G>A splice_region MUC5B 1 81206 1.23144E-5 40603 0 NA
11-1252656-A-G p.Asn518Ser missense MUC5B 3 81440 3.68369E-5 40720 0 4.06937E-6
11-1252658-A-T p.Ile519Phe missense MUC5B 1 81478 1.22733E-5 40739 0 3.49724E-5
11-1252662-C-T p.Thr520Ile missense MUC5B 4 81550 4.90497E-5 40775 0 1.48244E-4
11-1252677-C-T p.Ser525Leu missense MUC5B 1 81700 1.22399E-5 40850 0 4.05729E-6
11-1252678-G-A p.Ser525Ser synonymous MUC5B 1 81712 1.22381E-5 40856 0 NA
11-1252690-C-T p.Ile529Ile synonymous MUC5B 2 81760 2.44618E-5 40880 0 6.37146E-5
11-1252694-G-A p.Val531Met missense MUC5B 1 81746 1.2233E-5 40873 0 NA
11-1252704-G-C p.Gly534Ala missense MUC5B 1 81722 1.22366E-5 40861 0 NA
11-1252708-G-C p.Leu535Leu synonymous MUC5B 42930 81320 0.527914 40660 11549 0.549971
11-1252708-G-T p.Leu535Leu synonymous MUC5B 9 81736 1.10111E-4 40868 0 1.4482E-4
11-1252709-G-A p.Gly536Arg missense MUC5B 1 81720 1.22369E-5 40860 0 NA
11-1252723-G-A p.Leu540Leu synonymous MUC5B 1 81676 1.22435E-5 40838 0 1.2328E-5
11-1252738-A-T p.Pro545Pro synonymous MUC5B 2 81560 2.45218E-5 40780 0 NA
11-1252741-C-T p.Leu546Leu synonymous MUC5B 1 81564 1.22603E-5 40782 0 4.31678E-6
11-1252742-A-T p.Met547Leu missense MUC5B 1 81550 1.22624E-5 40775 0 1.29621E-5
11-1252743-T-C p.Met547Thr missense MUC5B 1 81542 1.22636E-5 40771 0 NA
11-1252754-G-T p.Val551Phe missense MUC5B 1 81454 1.22769E-5 40727 0 3.18532E-5
11-1252766-C-G p.Pro555Ala missense MUC5B 1 81204 1.23147E-5 40602 0 NA
11-1252767-C-T p.Pro555Leu missense MUC5B 1 81210 1.23138E-5 40605 0 NA
11-1252768-C-T p.Pro555Pro synonymous MUC5B 1 81178 1.23186E-5 40589 0 3.18634E-5
11-1252772-C-T p.His557Tyr missense MUC5B 3 81114 3.6985E-5 40557 0 0.00125
11-1252785-T-C p.Met561Thr missense MUC5B 2 80830 2.47433E-5 40415 0 NA
11-1252789-C-T p.Cys562Cys splice_region+synonymous MUC5B 1 80670 1.23962E-5 40335 0 6.25E-4
11-1252790-G-A p.Gly563Ser missense+splice_region MUC5B 2 80704 2.47819E-5 40352 0 NA
11-1252795-G-A c.1687+5G>A splice_region MUC5B 1 80518 1.24196E-5 40259 0 NA
11-1253219-C-A c.1688-7C>A splice_region MUC5B 2 79972 2.50088E-5 39986 0 4.06223E-6
11-1253222-C-T c.1688-4C>T splice_region MUC5B 1 80176 1.24726E-5 40088 0 8.57692E-6
11-1253260-C-T p.Asp574Asp synonymous MUC5B 4 81288 4.92078E-5 40644 0 3.37941E-5
11-1253269-G-A p.Thr577Thr synonymous MUC5B 3 81466 3.68252E-5 40733 0 1.21064E-5
11-1253278-C-T p.Ser580Ser synonymous MUC5B 2 81560 2.45218E-5 40780 0 0.00100806
11-1253278-C-CGG p.Val582fs frameshift MUC5B 1 81560 1.22609E-5 40780 0 NA
11-1253282-G-A p.Val582Met missense MUC5B 1 81612 1.22531E-5 40806 0 NA
11-1253282-G-T p.Val582Leu missense MUC5B 1 81612 1.22531E-5 40806 0 4.03568E-6
11-1253286-T-A p.Val583Glu missense MUC5B 7 81604 8.57801E-5 40802 0 3.19061E-5
11-1253295-C-T p.Thr586Met missense MUC5B 1 81704 1.22393E-5 40852 0 2.42303E-5
11-1253299-C-T p.Gly587Gly synonymous MUC5B 2 81722 2.44732E-5 40861 0 4.23822E-5
11-1253301-C-T p.Ala588Val missense MUC5B 1 81800 1.22249E-5 40900 0 NA
11-1253308-C-T p.Phe590Phe synonymous MUC5B 2 81884 2.44248E-5 40942 0 5.04032E-4
11-1253309-G-A p.Ala591Thr missense MUC5B 3 81884 3.66372E-5 40942 0 6.37796E-5
11-1253347-C-T p.Ala603Ala synonymous MUC5B 1 82034 1.21901E-5 41017 0 NA
11-1253375-C-G p.Leu613Val missense MUC5B 1 81900 1.221E-5 40950 0 NA
11-1253397-C-G c.1852+7C>G splice_region MUC5B 1 81590 1.22564E-5 40795 0 1.00464E-5
11-1253673-C-T c.1853-7C>T splice_region MUC5B 98 80606 0.00121579 40303 0 0.00242409
11-1253687-C-T p.Tyr620Tyr synonymous MUC5B 2 80850 2.47372E-5 40425 0 3.20688E-5
11-1253691-C-T p.Arg622Trp missense MUC5B 253 80906 0.00312709 40453 0 0.00625
11-1253691-C-G p.Arg622Gly missense MUC5B 3 80906 3.70801E-5 40453 0 4.24888E-6
11-1253692-G-A p.Arg622Gln missense MUC5B 2 80928 2.47133E-5 40464 0 1.6949E-5
11-1253697-T-C p.Trp624Arg missense MUC5B 1 81154 1.23223E-5 40577 0 3.19081E-5
11-1253705-G-A p.Ser626Ser synonymous MUC5B 2 81236 2.46196E-5 40618 0 6.34019E-5
11-1253706-C-T p.Arg627Cys missense MUC5B 8 81262 9.8447E-5 40631 0 5.40559E-5
11-1253707-G-A p.Arg627His missense MUC5B 22 81266 2.70716E-4 40633 0 0.00232742
11-1253714-C-G p.Thr629Thr synonymous MUC5B 1 81382 1.22877E-5 40691 0 2.35095E-5
11-1253715-G-T p.Asp630Tyr missense MUC5B 1 81420 1.2282E-5 40710 0 NA
11-1253719-C-T p.Pro631Leu missense MUC5B 11 81520 1.34936E-4 40760 0 3.55032E-4
11-1253723-C-A p.Asn632Lys missense MUC5B 7 81562 8.58243E-5 40781 0 3.50441E-4
11-1253723-C-T p.Asn632Asn synonymous MUC5B 1 81562 1.22606E-5 40781 0 2.26091E-5
11-1253735-G-A p.Ser636Ser synonymous MUC5B 1 81534 1.22648E-5 40767 0 3.32329E-5
11-1253736-C-T p.Arg637Cys missense MUC5B 4 81552 4.90485E-5 40776 0 1.10405E-5
11-1253750-C-T p.Ile641Ile synonymous MUC5B 1 81688 1.22417E-5 40844 0 2.13977E-5
11-1253758-C-T p.Pro644Leu missense MUC5B 1 81596 1.22555E-5 40798 0 NA
11-1253769-C-T p.His648Tyr missense MUC5B 3 81480 3.68189E-5 40740 0 1.2462E-5
11-1253771-C-T p.His648His synonymous MUC5B 16 81448 1.96444E-4 40724 0 7.51285E-4
11-1253773-C-T p.Ser649Leu missense+splice_region MUC5B 98 81398 0.00120396 40699 0 0.00307926
11-1253870-G-A c.1948-4G>A splice_region MUC5B 2 77444 2.58251E-5 38722 0 1.08667E-5
11-1253904-C-T p.Arg660Trp missense MUC5B 87 72974 0.00119221 36487 0 0.00347244
11-1253908-G-A p.Ser661Asn missense MUC5B 1 71636 1.39595E-5 35818 0 4.19812E-6
11-1253924-C-T p.Cys666Cys synonymous MUC5B 69 68504 0.00100724 34252 0 0.00216602
11-1253925-G-A p.Ala667Thr missense MUC5B 6 67974 8.8269E-5 33987 0 6.25E-4
11-1253928-G-T p.Ala668Ser missense MUC5B 2 67226 2.97504E-5 33613 0 6.36699E-5
11-1253929-C-T p.Ala668Val missense MUC5B 2 67076 2.98169E-5 33538 0 1.2734E-4
11-1253942-T-C p.Tyr672Tyr synonymous MUC5B 29543 59472 0.496755 29736 7600 0.643983
11-1253948-C-T p.His674His synonymous MUC5B 1 63310 1.57953E-5 31655 0 2.23015E-4
11-1253950-C-A p.Ala675Asp missense MUC5B 1 62878 1.59038E-5 31439 0 NA
11-1253957-C-G p.Ala677Ala synonymous MUC5B 2 61398 3.25743E-5 30699 0 1.28054E-5
11-1253958-G-A p.Ala678Thr missense MUC5B 3 61458 4.88138E-5 30729 0 2.22887E-4
11-1253967-G-A p.Val681Ile missense MUC5B 20 60208 3.32182E-4 30104 0 1.07273E-4
11-1253973-C-T p.Leu683Phe missense MUC5B 1 59338 1.68526E-5 29669 0 NA
11-1253978-C-T p.Ser684Ser synonymous MUC5B 1 57998 1.7242E-5 28999 0 3.1835E-5
11-1253979-G-A p.Asp685Asn missense MUC5B 3 58000 5.17241E-5 29000 0 9.86116E-6
11-1253990-C-T p.Asp688Asp synonymous MUC5B 2 56190 3.55935E-5 28095 0 5.05561E-4
11-1253994-G-A p.Val690Ile missense MUC5B 3 55186 5.43616E-5 27593 0 9.5511E-5
11-1254245-A-G p.Lys693Glu missense+splice_region MUC5B 20 73404 2.72465E-4 36702 0 3.18776E-4
11-1254259-C-G p.Asn697Lys missense MUC5B 2 74694 2.67759E-5 37347 0 1.78586E-5
11-1254267-A-T p.Lys700Met missense MUC5B 2 75288 2.65647E-5 37644 0 2.18908E-5
11-1254268-G-A p.Lys700Lys synonymous MUC5B 9 75360 1.19427E-4 37680 0 6.89862E-4
11-1254275-C-T p.Arg703Cys missense MUC5B 8 75496 1.05966E-4 37748 0 4.76756E-5
11-1254276-G-T p.Arg703Leu missense MUC5B 1 75604 1.32268E-5 37802 0 NA
11-1254280-C-T p.Tyr704Tyr synonymous MUC5B 514 76062 0.00675764 38031 4 0.025625
11-1254281-G-A p.Ala705Thr missense MUC5B 2 76074 2.62902E-5 38037 0 5.57657E-5
11-1254286-C-T p.Tyr706Tyr synonymous MUC5B 6 76586 7.83433E-5 38293 0 6.37389E-5
11-1254287-G-A p.Val707Met missense MUC5B 22 76610 2.87169E-4 38305 0 6.25E-4
11-1254295-T-A p.Asp709Glu missense MUC5B 14 76826 1.8223E-4 38413 0 2.86971E-4
11-1254305-C-G p.Pro713Ala missense MUC5B 3 77046 3.89378E-5 38523 0 1.03571E-4
11-1254315-G-C p.Arg716Pro missense MUC5B 2 76748 2.60593E-5 38374 0 6.95396E-5
11-1254316-C-T p.Arg716Arg synonymous MUC5B 3 76748 3.9089E-5 38374 0 3.06755E-4
11-1254317-G-A p.Gly717Ser missense MUC5B 8 76850 1.04099E-4 38425 0 2.23157E-4
11-1254318-G-T p.Gly717Val missense MUC5B 1 76904 1.30032E-5 38452 0 1.27167E-4
11-1254320-CTGAG-C p.Ser719fs frameshift MUC5B 1 77038 1.29806E-5 38519 0 4.18305E-6
11-1254325-T-G p.Ser719Arg missense MUC5B 1 77088 1.29722E-5 38544 0 4.18393E-6
11-1254331-C-T p.Ala721Ala synonymous MUC5B 2 77050 2.59572E-5 38525 0 3.19101E-5
11-1254332-G-A p.Asp722Asn missense MUC5B 1 77000 1.2987E-5 38500 0 3.18695E-5
11-1254334-C-T p.Asp722Asp synonymous MUC5B 5 77028 6.49115E-5 38514 0 6.37186E-5
11-1254337-C-T p.Val723Val synonymous MUC5B 1 76872 1.30086E-5 38436 0 4.16861E-6
11-1254342-G-T p.Cys725Phe missense MUC5B 2 76850 2.60247E-5 38425 0 2.79111E-5
11-1254356-G-A p.Val730Met missense MUC5B 4 76298 5.2426E-5 38149 0 7.10994E-5
11-1254367-C-T p.Asp733Asp synonymous MUC5B 9 75412 1.19344E-4 37706 0 1.27535E-4
11-1254382-C-T p.Pro738Pro synonymous MUC5B 1 74224 1.34727E-5 37112 0 1.59317E-4
11-1254383-G-A p.Ala739Thr missense MUC5B 1 73798 1.35505E-5 36899 0 3.87034E-5
11-1254384-C-T p.Ala739Val missense MUC5B 1 73716 1.35656E-5 36858 0 5.05561E-4
11-1254385-G-A p.Ala739Ala synonymous MUC5B 6 73634 8.14841E-5 36817 0 2.62539E-4
11-1254387-G-A p.Gly740Asp missense MUC5B 1 73250 1.36519E-5 36625 0 NA
11-1254388-C-T p.Gly740Gly synonymous MUC5B 15 73176 2.04985E-4 36588 0 5.91308E-5
11-1254390-C-A p.Thr741Asn missense MUC5B 23 73220 3.14122E-4 36610 0 0.00125
11-1254396-T-A p.Leu743His missense MUC5B 1 72578 1.37783E-5 36289 0 NA
11-1254405-C-G p.Ala746Gly missense MUC5B 1 70518 1.41808E-5 35259 0 NA
11-1254406-G-A p.Ala746Ala synonymous MUC5B 1 70218 1.42414E-5 35109 0 1.11577E-5
11-1254407-G-A p.Gly747Ser missense MUC5B 78 69940 0.00111524 34970 0 0.00154947
11-1254409-C-T p.Gly747Gly synonymous MUC5B 2 69136 2.89285E-5 34568 0 3.18613E-5
11-1254410-G-A p.Ala748Thr missense MUC5B 1 69096 1.44726E-5 34548 0 2.28477E-5
11-1254416-G-A p.Val750Met missense MUC5B 2 68358 2.92577E-5 34179 1 5.06073E-4
11-1254420-C-G p.Pro751Arg missense MUC5B 1 67400 1.48368E-5 33700 0 NA
11-1254421-C-T p.Pro751Pro synonymous MUC5B 3 67114 4.47001E-5 33557 0 4.91244E-5
11-1254422-G-A p.Ala752Thr missense MUC5B 2 66658 3.00039E-5 33329 0 5.04796E-5
11-1254435-C-T p.Pro756Leu missense MUC5B 2 64496 3.10097E-5 32248 0 1.22853E-4
11-1254442-C-T p.Tyr758Tyr synonymous MUC5B 36 62448 5.7648E-4 31224 0 0.0015213
11-1254448-C-T p.His760His synonymous MUC5B 54 60648 8.90384E-4 30324 0 0.00200867
11-1254454-C-T p.Thr762Thr synonymous MUC5B 5 58466 8.55198E-5 29233 0 5.07099E-4
11-1254455-G-A p.Val763Met missense MUC5B 1 58208 1.71798E-5 29104 0 6.25E-4
11-1254473-G-A p.Val769Met missense MUC5B 2 53978 3.70521E-5 26989 0 NA
11-1254481-C-T p.His771His synonymous MUC5B 1 51456 1.94341E-5 25728 0 9.5761E-5
11-1254481-C-A p.His771Gln missense MUC5B 6 51458 1.166E-4 25729 0 2.39189E-4
11-1254484-C-T p.Asp772Asp synonymous MUC5B 2 50556 3.95601E-5 25278 0 0.00256148
11-1254490-C-T p.Gly774Gly synonymous MUC5B 2 48890 4.09082E-5 24445 0 6.38325E-5
11-1254493-C-T p.Ala775Ala synonymous MUC5B 4 48012 8.33125E-5 24006 0 6.3804E-5
11-1254494-G-A p.Val776Met missense MUC5B 5 48148 1.03846E-4 24074 0 9.57304E-5
11-1255023-T-C p.Cys777Cys splice_region+synonymous MUC5B 1 81252 1.23074E-5 40626 0 1.5877E-5
11-1255031-C-T p.Thr780Met missense MUC5B 4 81162 4.92841E-5 40581 0 1.67913E-4
11-1255032-G-A p.Thr780Thr synonymous MUC5B 441 81192 0.00543157 40596 9 0.0117222
11-1255034-G-A p.Gly781Asp missense MUC5B 5 81200 6.15764E-5 40600 0 0.00125
11-1255068-G-C p.Gln792His missense MUC5B 8 80788 9.90246E-5 40394 0 5.13347E-4
11-1255073-G-A p.Ser794Asn missense MUC5B 1 80634 1.24017E-5 40317 0 NA
11-1255436-G-A p.Gly796Gly splice_region+synonymous MUC5B 1 77874 1.28413E-5 38937 0 3.19142E-5
11-1255445-C-T p.Ala799Ala synonymous MUC5B 13 78088 1.66479E-4 39044 0 5.10725E-4
11-1255454-G-A p.Val802Val synonymous MUC5B 1 78360 1.27616E-5 39180 0 NA
11-1255461-G-T p.Asp805Tyr missense MUC5B 3 78484 3.82244E-5 39242 0 5.10204E-4
11-1255467-A-G p.Ser807Gly missense MUC5B 1 78580 1.27259E-5 39290 0 1.29671E-5
11-1255468-G-A p.Ser807Asn missense MUC5B 1 78574 1.27269E-5 39287 0 3.90422E-5
11-1255475-C-T p.Ser809Ser synonymous MUC5B 1 78540 1.27324E-5 39270 0 2.58518E-5
11-1255477-C-T p.Ser810Leu missense MUC5B 2 78472 2.54868E-5 39236 0 2.58438E-5
11-1255481-G-A p.Ala811Ala synonymous MUC5B 1 78518 1.27359E-5 39259 0 8.58391E-6
11-1255486-C-A p.Thr813Asn missense MUC5B 227 78376 0.00289629 39188 0 0.0127551
11-1255495-C-G p.Ala816Gly missense MUC5B 4 78202 5.11496E-5 39101 0 3.19101E-5
11-1255495-C-T p.Ala816Val missense MUC5B 2 78202 2.55748E-5 39101 0 1.31999E-5
11-1255496-C-T p.Ala816Ala synonymous MUC5B 2 78214 2.55709E-5 39107 0 1.05533E-4
11-1255499-G-C p.Glu817Asp missense MUC5B 2 78316 2.55376E-5 39158 0 5.2694E-5
11-1255502-C-T p.Cys818Cys synonymous MUC5B 1 78336 1.27655E-5 39168 0 NA
11-1255504-T-A p.Leu819His missense MUC5B 1 78390 1.27567E-5 39195 0 5.09684E-4
11-1255506-C-T p.Arg820Trp missense MUC5B 1 78472 1.27434E-5 39236 0 6.90417E-5
11-1255519-C-T p.Thr824Met missense MUC5B 1 78448 1.27473E-5 39224 0 2.18125E-5
11-1255519-C-G p.Thr824Arg missense MUC5B 1 78448 1.27473E-5 39224 0 4.36251E-6
11-1255520-G-A p.Thr824Thr synonymous MUC5B 2 78406 2.55083E-5 39203 0 1.43521E-5
11-1255526-C-T p.Asp826Asp synonymous MUC5B 2 78432 2.54998E-5 39216 0 4.41911E-5
11-1255527-G-A p.Val827Met missense MUC5B 9 78460 1.14708E-4 39230 0 0.00188206
11-1255534-G-A p.Cys829Tyr missense+splice_region MUC5B 1 78510 1.27372E-5 39255 0 NA
11-1255543-C-A c.2487+8C>A splice_region MUC5B 1 78582 1.27256E-5 39291 0 5.97954E-5
11-1255766-C-T p.Thr832Ile missense MUC5B 2 79142 2.5271E-5 39571 0 5.10142E-6
11-1255767-A-C p.Thr832Thr synonymous MUC5B 1 79122 1.26387E-5 39561 0 NA
11-1255773-C-T p.Cys834Cys synonymous MUC5B 23577 78570 0.300076 39285 3768 0.379787
11-1255774-G-A p.Val835Met missense MUC5B 1 79424 1.25907E-5 39712 0 3.19122E-5
11-1255779-C-T p.Ser836Ser synonymous MUC5B 1 79602 1.25625E-5 39801 0 NA
11-1255779-C-A p.Ser836Ser synonymous MUC5B 2 79602 2.5125E-5 39801 0 1.00901E-5
11-1255780-G-A p.Gly837Ser missense MUC5B 1 79692 1.25483E-5 39846 0 7.61653E-5
11-1255781-G-A p.Gly837Asp missense MUC5B 1 79712 1.25452E-5 39856 0 NA
11-1255796-C-T p.Pro842Leu missense MUC5B 4 80158 4.99014E-5 40079 0 0.00101937
11-1255796-C-G p.Pro842Arg missense MUC5B 2 80158 2.49507E-5 40079 0 5.04724E-6
11-1255808-C-T p.Ser846Leu missense MUC5B 2 80296 2.49078E-5 40148 0 1.40292E-4
11-1255809-G-A p.Ser846Ser synonymous MUC5B 1 80370 1.24425E-5 40185 0 0.00102669
11-1255819-G-T p.Gly850Trp missense MUC5B 1 80446 1.24307E-5 40223 0 5.31655E-6
11-1255822-G-A p.Gly851Ser missense MUC5B 1 80440 1.24316E-5 40220 0 1.91571E-4
11-1255823-G-T p.Gly851Val missense MUC5B 1 80438 1.24319E-5 40219 0 3.19203E-5
11-1255829-T-C p.Ile853Thr missense MUC5B 4 80496 4.96919E-5 40248 0 1.29374E-4
11-1255833-C-T p.Ala854Ala synonymous MUC5B 2 80460 2.48571E-5 40230 0 5.65784E-6
11-1255833-C-G p.Ala854Ala synonymous MUC5B 1 80460 1.24285E-5 40230 0 NA
11-1255834-G-A p.Glu855Lys missense MUC5B 1 80484 1.24248E-5 40242 0 3.19326E-5
11-1255839-G-T p.Glu856Asp missense MUC5B 1 80502 1.24221E-5 40251 0 NA
11-1255839-G-A p.Glu856Glu synonymous MUC5B 2 80502 2.48441E-5 40251 0 NA
11-1255848-C-T p.Pro859Pro synonymous MUC5B 2 80464 2.48558E-5 40232 0 NA
11-1255853-T-C p.Val861Ala missense MUC5B 1 80444 1.2431E-5 40222 0 NA
11-1255860-C-T p.Asn863Asn synonymous MUC5B 8 80296 9.96314E-5 40148 0 4.69087E-5
11-1255867-A-C p.Thr866Pro missense MUC5B 1 80076 1.24881E-5 40038 0 NA
11-1255868-C-G p.Thr866Ser missense MUC5B 3 80068 3.74682E-5 40034 0 3.21523E-5
11-1255869-C-T p.Thr866Thr synonymous MUC5B 2 80068 2.49788E-5 40034 0 9.61477E-5
11-1255880-G-A p.Gly870Glu missense MUC5B 3 79726 3.76289E-5 39863 0 1.06872E-4
11-1255896-C-A p.Val875Val synonymous MUC5B 4 78264 5.11091E-5 39132 0 NA
11-1255896-C-T p.Val875Val synonymous MUC5B 1 78264 1.27773E-5 39132 0 1.33941E-5
11-1255899-C-A p.Asp876Glu missense MUC5B 1 77960 1.28271E-5 38980 0 NA
11-1255899-C-T p.Asp876Asp synonymous MUC5B 1 77960 1.28271E-5 38980 0 3.23541E-5
11-1255908-C-T p.Thr879Thr splice_region+synonymous MUC5B 3 76722 3.91022E-5 38361 0 NA
11-1255911-G-A c.2639+1G>A splice_donor MUC5B 1 76190 1.31251E-5 38095 0 NA
11-1255915-G-T c.2639+5G>T splice_region MUC5B 2 75448 2.65083E-5 37724 0 NA
11-1255917-CGTGA-C c.2639+8_2639+11delGTGA splice_region MUC5B 1 74600 1.34048E-5 37300 0 NA
11-1256323-G-C p.Arg883Thr missense MUC5B 3 81786 3.66811E-5 40893 0 1.05519E-4
11-1256326-A-T p.Asn884Ile missense MUC5B 5 81806 6.11202E-5 40903 0 3.1902E-5
11-1256329-G-A p.Arg885Gln missense MUC5B 3 81844 3.66551E-5 40922 0 3.19E-5
11-1256337-G-C p.Glu888Gln missense MUC5B 2 81918 2.44147E-5 40959 0 NA
11-1256345-C-T p.Ser890Ser synonymous MUC5B 1 81910 1.22085E-5 40955 0 4.05039E-6
11-1256349-C-T p.Arg892Trp missense MUC5B 18 81976 2.19576E-4 40988 0 4.78713E-4
11-1256349-C-A p.Arg892Arg synonymous MUC5B 1 81976 1.21987E-5 40988 0 3.19142E-5
11-1256350-G-A p.Arg892Gln missense MUC5B 2 81996 2.43914E-5 40998 0 6.38407E-5
11-1256354-C-T p.Leu893Leu synonymous MUC5B 1 82028 1.2191E-5 41014 0 NA
11-1256355-T-C p.Cys894Arg missense MUC5B 1 82046 1.21883E-5 41023 0 NA
11-1256358-C-T p.Leu895Leu synonymous MUC5B 1 82070 1.21847E-5 41035 0 NA
11-1256369-C-T p.Cys898Cys synonymous MUC5B 1 82076 1.21838E-5 41038 0 1.01281E-4
11-1256370-G-A p.Val899Met missense MUC5B 1 82090 1.21818E-5 41045 0 NA
11-1256388-C-T p.His905Tyr missense MUC5B 2 82154 2.43445E-5 41077 0 NA
11-1256408-C-T p.Gly911Gly synonymous MUC5B 6 82194 7.2998E-5 41097 0 4.18361E-5
11-1256409-G-A p.Asp912Asn missense MUC5B 19 82204 2.31132E-4 41102 0 0.003125
11-1256412-C-T p.Arg913Cys missense MUC5B 2 82198 2.43315E-5 41099 0 6.38244E-5
11-1256413-G-A p.Arg913His missense MUC5B 1 82188 1.21672E-5 41094 0 1.20702E-5
11-1256436-G-A p.Glu921Lys missense MUC5B 1 82208 1.21643E-5 41104 0 5.03525E-4
11-1256457-C-T c.2778+4C>T splice_region MUC5B 768 82174 0.00934602 41087 15 0.0187256
11-1256458-G-A c.2778+5G>A splice_region MUC5B 2 82160 2.43427E-5 41080 0 2.82215E-5
11-1256460-C-T c.2778+7C>T splice_region MUC5B 3 82172 3.65088E-5 41086 0 1.674E-5
11-1256543-G-A p.Gly930Glu missense MUC5B 1 82232 1.21607E-5 41116 0 NA
11-1256548-A-G p.Asn932Asp missense MUC5B 1 82212 1.21637E-5 41106 0 2.52241E-5
11-1256549-A-C p.Asn932Thr missense MUC5B 160 82204 0.00194638 41102 0 0.00655903
11-1256554-A-C p.Thr934Pro missense MUC5B 1 82168 1.21702E-5 41084 0 6.25E-4
11-1256556-C-A p.Thr934Thr synonymous MUC5B 9 82208 1.09478E-4 41104 0 0.00100908
11-1256559-C-T p.His935His synonymous MUC5B 3 82206 3.64937E-5 41103 0 9.5957E-5
11-1256569-C-T p.Arg939Cys missense MUC5B 1 82232 1.21607E-5 41116 0 8.44281E-6
11-1256570-G-A p.Arg939His missense MUC5B 13 82214 1.58124E-4 41107 0 4.47199E-4
11-1256574-C-T p.Ile940Ile synonymous MUC5B 1 82226 1.21616E-5 41113 0 6.39386E-5
11-1256580-C-T p.Thr942Thr synonymous MUC5B 6 82206 7.29874E-5 41103 0 1.27689E-4
11-1256586-C-T p.Asn944Asn synonymous MUC5B 4 82202 4.86606E-5 41101 0 3.39253E-5
11-1256588-T-A p.Ile945Asn missense MUC5B 2 82184 2.43356E-5 41092 0 NA
11-1256595-T-C p.Cys947Cys synonymous MUC5B 2 82172 2.43392E-5 41086 0 4.83359E-4
11-1256600-C-A p.Thr949Asn missense MUC5B 3 82144 3.65212E-5 41072 0 5.14827E-5
11-1256604-C-T p.Thr950Thr synonymous MUC5B 3 82140 3.6523E-5 41070 0 5.04541E-4
11-1256606-G-A p.Gly951Asp missense MUC5B 1 82110 1.21788E-5 41055 0 NA
11-1256610-C-T p.Thr952Thr synonymous MUC5B 2 82106 2.43588E-5 41053 0 5.04541E-4
11-1256626-A-C p.Ile958Leu missense MUC5B 1 82056 1.21868E-5 41028 0 NA
11-1256637-C-T p.Phe961Phe synonymous MUC5B 4 81932 4.8821E-5 40966 0 6.25E-4
11-1256638-G-T p.Val962Leu missense MUC5B 9 81932 1.09847E-4 40966 0 1.931E-4
11-1256643-G-T p.Glu963Asp missense+splice_region MUC5B 1 81884 1.22124E-5 40942 0 NA
11-1256646-G-A c.2889+3G>A splice_region MUC5B 11 81816 1.34448E-4 40908 0 0.0025
11-1256648-GA-AG c.2889+5_2889+6delGAinsAG splice_region MUC5B 2 81776 2.44571E-5 40888 0 NA
11-1257633-C-T p.Leu969Leu synonymous MUC5B 1 80872 1.23652E-5 40436 0 NA
11-1257641-G-T p.Gly972Val missense MUC5B 1 81202 1.2315E-5 40601 0 NA
11-1257645-C-A p.Thr973Thr synonymous MUC5B 2 81316 2.45954E-5 40658 0 6.38081E-5
11-1257653-C-T p.Ala976Val missense MUC5B 20 81604 2.45086E-4 40802 0 1.2513E-4
11-1257653-CGGT-C p.Val977del disruptive_inframe_deletion MUC5B 2 81606 2.4508E-5 40803 0 NA
11-1257654-G-A p.Ala976Ala synonymous MUC5B 98 81660 0.0012001 40830 0 0.00264685
11-1257659-C-A p.Ala978Glu missense MUC5B 3 81708 3.67161E-5 40854 0 0.00100705
11-1257659-C-T p.Ala978Val missense MUC5B 2 81708 2.44774E-5 40854 0 2.42029E-5
11-1257660-G-A p.Ala978Ala synonymous MUC5B 11 81784 1.34501E-4 40892 0 5.64539E-5
11-1257664-G-A p.Gly980Arg missense MUC5B 3 81884 3.66372E-5 40942 0 NA
11-1257664-G-C p.Gly980Arg missense MUC5B 2 81884 2.44248E-5 40942 0 NA
11-1257666-G-T p.Gly980Gly synonymous MUC5B 1 81928 1.22058E-5 40964 0 NA
11-1257668-C-T p.Pro981Leu missense MUC5B 8 81940 9.76324E-5 40970 0 1.81402E-4
11-1257669-G-A p.Pro981Pro synonymous MUC5B 4 81986 4.87888E-5 40993 0 5.04032E-4
11-1257670-G-T p.Gly982Cys missense MUC5B 1 82022 1.21919E-5 41011 0 4.02914E-6
11-1257670-G-C p.Gly982Arg missense MUC5B 1 82022 1.21919E-5 41011 0 NA
11-1257694-C-T p.Arg990Cys missense MUC5B 1 82222 1.21622E-5 41111 0 1.20725E-5
11-1257695-G-A p.Arg990His missense MUC5B 4 82228 4.86452E-5 41114 0 3.19081E-5
11-1257712-C-G p.Leu996Val missense MUC5B 1 82276 1.21542E-5 41138 0 8.04596E-6
11-1257723-G-C p.Glu999Asp missense MUC5B 1 82292 1.21518E-5 41146 0 NA
11-1257725-C-T p.Thr1000Ile missense MUC5B 1 82290 1.21521E-5 41145 0 NA
11-1257729-C-T p.His1001His synonymous MUC5B 3 82296 3.64538E-5 41148 0 6.37714E-5
11-1257730-G-A p.Gly1002Arg missense MUC5B 3 82292 3.64555E-5 41146 0 9.56816E-5
11-1257730-G-C p.Gly1002Arg missense MUC5B 2 82292 2.43037E-5 41146 0 NA
11-1257738-C-T p.Ala1004Ala synonymous MUC5B 2 82286 2.43055E-5 41143 0 NA
11-1257738-C-G p.Ala1004Ala synonymous MUC5B 1 82286 1.21527E-5 41143 0 2.0116E-5
11-1257751-C-T p.Arg1009Trp missense MUC5B 2 82260 2.43132E-5 41130 0 9.56633E-5
11-1257752-G-A p.Arg1009Gln missense MUC5B 3 82250 3.64742E-5 41125 0 1.60974E-5
11-1257753-G-A p.Arg1009Arg synonymous MUC5B 1 82254 1.21575E-5 41127 0 4.02447E-6
11-1257762-C-T p.Ser1012Ser synonymous MUC5B 1 82230 1.2161E-5 41115 0 2.01313E-5
11-1257763-G-A p.Val1013Met missense MUC5B 12 82232 1.45929E-4 41116 0 0.00100705
11-1257773-G-A p.Arg1016Gln missense MUC5B 1 82142 1.2174E-5 41071 0 3.18817E-5
11-1257789-C-A p.Tyr1021* stop_gained MUC5B 1 81976 1.21987E-5 40988 0 4.03528E-6
11-1257789-C-T p.Tyr1021Tyr synonymous MUC5B 1 81976 1.21987E-5 40988 0 NA
11-1257800-C-T c.3066+8C>T splice_region MUC5B 9 81618 1.1027E-4 40809 0 3.64449E-5
11-1258157-C-T p.Gly1023Gly splice_region+synonymous MUC5B 1 78538 1.27327E-5 39269 0 NA
11-1258166-C-T p.Cys1026Cys synonymous MUC5B 9 79042 1.13864E-4 39521 0 8.56311E-5
11-1258175-C-T p.Cys1029Cys synonymous MUC5B 2 79298 2.52213E-5 39649 0 0.398373
11-1258184-C-T p.Phe1032Phe synonymous MUC5B 697 79518 0.00876531 39759 3 0.016875
11-1258187-C-T p.Asp1033Asp synonymous MUC5B 2 79698 2.50947E-5 39849 0 9.55353E-5
11-1258199-C-G p.Ile1037Met missense MUC5B 1 80418 1.2435E-5 40209 0 NA
11-1258213-C-T p.Thr1042Met missense MUC5B 77 80848 9.52405E-4 40424 1 0.0040282
11-1258216-G-A p.Arg1043His missense MUC5B 4 80928 4.94266E-5 40464 0 9.55597E-5
11-1258221-C-T p.Arg1045Trp missense MUC5B 7 81020 8.63984E-5 40510 0 3.6077E-5
11-1258226-C-T p.Ser1046Ser synonymous MUC5B 125 81084 0.00154161 40542 0 0.399268
11-1258227-G-A p.Val1047Met missense MUC5B 11 81144 1.35561E-4 40572 0 1.1874E-4
11-1258228-T-C p.Val1047Ala missense MUC5B 1 81196 1.23159E-5 40598 0 4.38985E-6
11-1258233-G-A p.Gly1049Arg missense MUC5B 1 81220 1.23122E-5 40610 0 8.81368E-6
11-1258238-C-T p.Asp1050Asp synonymous MUC5B 20 81146 2.46469E-4 40573 0 1.91083E-4
11-1258256-C-T p.Asn1056Asn synonymous MUC5B 3 81206 3.69431E-5 40603 0 3.18431E-5
11-1258258-G-A p.Ser1057Asn missense MUC5B 1 81218 1.23125E-5 40609 0 NA
11-1258274-C-T p.Pro1062Pro synonymous MUC5B 1 81298 1.23004E-5 40649 0 1.28785E-5
11-1258274-C-G p.Pro1062Pro synonymous MUC5B 1 81298 1.23004E-5 40649 0 1.7138E-5
11-1258279-G-T p.Cys1064Phe missense MUC5B 1 81266 1.23053E-5 40633 0 NA
11-1258282-C-T p.Pro1065Leu missense MUC5B 3 81206 3.69431E-5 40603 0 6.3678E-5
11-1258283-G-A p.Pro1065Pro synonymous MUC5B 2 81126 2.4653E-5 40563 0 0.486463
11-1258286-C-T p.Asp1066Asp synonymous MUC5B 17 81118 2.09571E-4 40559 0 0.486529
11-1258287-G-T p.Ala1067Ser missense MUC5B 1 81086 1.23326E-5 40543 0 4.28581E-6
11-1258293-G-A p.Ala1069Thr missense MUC5B 3 81060 3.70096E-5 40530 0 6.3674E-5
11-1258306-C-A p.Pro1073His missense MUC5B 1 80914 1.23588E-5 40457 0 NA
11-1258313-G-A p.Thr1075Thr synonymous MUC5B 3 80594 3.72236E-5 40297 0 1.59195E-4
11-1258319-C-T p.Asn1077Asn synonymous MUC5B 1 80464 1.24279E-5 40232 0 6.25E-4
11-1258320-C-A p.Pro1078Thr missense MUC5B 5 80452 6.21489E-5 40226 0 4.4528E-6
11-1258326-C-T p.Arg1080Cys missense MUC5B 2 80132 2.49588E-5 40066 0 8.97924E-6
11-1258327-G-A p.Arg1080His missense MUC5B 2 80058 2.49819E-5 40029 0 1.2734E-4
11-1258340-C-G p.Ala1084Ala synonymous MUC5B 16 79558 2.01111E-4 39779 0 3.50185E-4
11-1258340-C-T p.Ala1084Ala synonymous MUC5B 5 79560 6.28457E-5 39780 0 6.36699E-5
11-1258349-G-A p.Gln1087Gln synonymous MUC5B 1 78948 1.26666E-5 39474 0 NA
11-1258359-C-T p.Leu1091Phe missense MUC5B 15 77636 1.93209E-4 38818 0 0.0019749
11-1258361-C-T p.Leu1091Leu synonymous MUC5B 2 77434 2.58284E-5 38717 0 9.01356E-6
11-1258364-C-T p.His1092His synonymous MUC5B 1 76762 1.30273E-5 38381 0 9.55171E-5
11-1258370-C-T p.Pro1094Pro synonymous MUC5B 1 76384 1.30917E-5 38192 0 NA
11-1258376-C-T p.Phe1096Phe synonymous MUC5B 4 75602 5.29087E-5 37801 0 6.44067E-5
11-1258377-G-A p.Ala1097Thr missense MUC5B 71 75116 9.45205E-4 37558 0 0.00156381
11-1258379-C-T p.Ala1097Ala synonymous MUC5B 5 75398 6.63148E-5 37699 0 5.06073E-4
11-1258387-G-A p.Arg1100His missense MUC5B 2 76870 2.6018E-5 38435 0 0.222839
11-1258390-C-A p.Ser1101Tyr missense MUC5B 1 76868 1.30093E-5 38434 0 NA
11-1260094-C-A c.3307-7C>A splice_region MUC5B 1 80380 1.24409E-5 40190 0 NA
11-1260096-C-T c.3307-5C>T splice_region MUC5B 5 80428 6.21674E-5 40214 0 6.37308E-5
11-1260097-G-A c.3307-4G>A splice_region MUC5B 2 80434 2.48651E-5 40217 0 8.1367E-5
11-1260097-G-T c.3307-4G>T splice_region MUC5B 1 80434 1.24326E-5 40217 0 5.67924E-5
11-1260106-C-T p.Asp1104Asp synonymous MUC5B 1 80756 1.2383E-5 40378 0 0.00204708
11-1260118-C-T p.Tyr1108Tyr synonymous MUC5B 6 81024 7.40521E-5 40512 0 5.07717E-5
11-1260125-G-A p.Ala1111Thr missense MUC5B 2 81086 2.46652E-5 40543 0 NA
11-1260130-C-T p.Cys1112Cys synonymous MUC5B 3 81086 3.69978E-5 40543 0 6.36943E-5
11-1260131-G-A p.Val1113Met missense MUC5B 2 81106 2.46591E-5 40553 0 1.39965E-4
11-1260136-C-T p.Asn1114Asn synonymous MUC5B 1 81142 1.23241E-5 40571 0 1.67566E-5
11-1260137-G-A p.Asp1115Asn missense MUC5B 1 81136 1.2325E-5 40568 0 1.11165E-5
11-1260139-C-T p.Asp1115Asp synonymous MUC5B 3 81152 3.69677E-5 40576 0 8.97424E-5
11-1260142-G-A p.Ala1116Ala synonymous MUC5B 2 81184 2.46354E-5 40592 0 0.00152439
11-1260151-C-T p.Cys1119Cys synonymous MUC5B 1 81160 1.23213E-5 40580 0 4.18866E-5
11-1260156-C-T p.Ser1121Leu missense MUC5B 1 81176 1.23189E-5 40588 0 5.36653E-6
11-1260157-G-A p.Ser1121Ser synonymous MUC5B 105 81180 0.00129342 40590 0 0.00351164
11-1260160-T-C p.Gly1122Gly synonymous MUC5B 2 81150 2.46457E-5 40575 0 4.04138E-5
11-1260160-T-A p.Gly1122Gly synonymous MUC5B 1 81150 1.23229E-5 40575 0 5.33544E-6
11-1260163-C-T p.Gly1123Gly synonymous MUC5B 5 81128 6.1631E-5 40564 0 0.385825
11-1260164-G-A p.Asp1124Asn missense MUC5B 2 81134 2.46506E-5 40567 0 4.23639E-5
11-1260184-G-A p.Thr1130Thr synonymous MUC5B 89 81062 0.00109793 40531 0 0.00211682
11-1260193-T-A p.Ala1133Ala synonymous MUC5B 1 80974 1.23496E-5 40487 0 4.03388E-5
11-1260199-C-T p.Tyr1135Tyr synonymous MUC5B 12 80818 1.48482E-4 40409 0 9.55597E-5
11-1260200-G-T p.Ala1136Ser missense MUC5B 1 80722 1.23882E-5 40361 0 NA
11-1260214-C-G p.His1140Gln missense MUC5B 1 80610 1.24054E-5 40305 0 5.61709E-6
11-1260215-G-A p.Asp1141Asn missense MUC5B 1 80568 1.24119E-5 40284 0 3.35608E-5
11-1260217-C-T p.Asp1141Asp synonymous MUC5B 1 80540 1.24162E-5 40270 0 4.47277E-5
11-1260219-C-G p.Ala1142Gly missense MUC5B 1 80482 1.24251E-5 40241 0 5.57631E-6
11-1260219-C-T p.Ala1142Val missense MUC5B 1 80482 1.24251E-5 40241 0 0.385331
11-1260220-G-C p.Ala1142Ala synonymous MUC5B 23 80642 2.85211E-4 40321 0 5.63698E-4
11-1260220-G-A p.Ala1142Ala synonymous MUC5B 3 80642 3.72015E-5 40321 0 0.385006
11-1260233-T-C p.Ser1147Pro missense MUC5B 1 80414 1.24356E-5 40207 0 NA
11-1260235-C-T p.Ser1147Ser synonymous MUC5B 1 80406 1.24369E-5 40203 0 NA
11-1260239-C-A p.Arg1149Arg synonymous MUC5B 33 80162 4.11666E-4 40081 0 0.001875
11-1260240-G-A p.Arg1149Gln missense MUC5B 1 80172 1.24732E-5 40086 0 NA
11-1260247-G-A p.Pro1151Pro synonymous MUC5B 5 80004 6.24969E-5 40002 0 8.10636E-5
11-1260247-G-C p.Pro1151Pro synonymous MUC5B 30 80000 3.75E-4 40000 0 0.00348573
11-1260257-C-T p.Pro1155Ser missense+splice_region MUC5B 8 80212 9.97357E-5 40106 0 1.92946E-4
11-1260264-C-T c.3463+7C>T splice_region MUC5B 3 80074 3.74653E-5 40037 0 1.16695E-4
11-1260265-G-T c.3463+8G>T splice_region MUC5B 1 80050 1.24922E-5 40025 0 3.99954E-4
11-1260265-G-A c.3463+8G>A splice_region MUC5B 4 80050 4.99688E-5 40025 0 1.14273E-4
11-1260696-T-C p.His1164His synonymous MUC5B 9 82326 1.09321E-4 41163 0 5.03525E-4
11-1260700-G-T p.Gly1166Cys missense MUC5B 3 82322 3.64423E-5 41161 0 4.07448E-6
11-1260701-G-A p.Gly1166Asp missense MUC5B 1 82320 1.21477E-5 41160 0 NA
11-1260705-T-C p.Cys1167Cys synonymous MUC5B 2 82346 2.42878E-5 41173 0 NA
11-1260726-C-T p.Cys1174Cys synonymous MUC5B 7 82346 8.50072E-5 41173 0 1.83896E-4
11-1260727-G-A p.Gly1175Arg missense MUC5B 18 82346 2.1859E-4 41173 0 1.91327E-4
11-1260745-A-T p.Thr1181Ser missense MUC5B 1 82356 1.21424E-5 41178 0 NA
11-1260751-C-T p.Arg1183Trp missense MUC5B 2 82378 2.42783E-5 41189 0 3.46789E-5
11-1260752-G-A p.Arg1183Gln missense MUC5B 1 82374 1.21398E-5 41187 0 3.18837E-5
11-1260753-G-T p.Arg1183Arg synonymous MUC5B 2 82372 2.42801E-5 41186 0 8.6804E-6
11-1260763-G-A p.Gly1187Arg missense MUC5B 1 82374 1.21398E-5 41187 0 NA
11-1260768-C-T p.His1188His synonymous MUC5B 1 82354 1.21427E-5 41177 0 3.18837E-5
11-1260780-C-T p.Asp1192Asp synonymous MUC5B 4 82346 4.85755E-5 41173 0 1.09753E-4
11-1260784-C-T p.Pro1194Ser missense MUC5B 7 82346 8.50072E-5 41173 0 9.59263E-5
11-1260785-CTGG-C p.Gly1195del disruptive_inframe_deletion MUC5B 4 82350 4.85732E-5 41175 0 3.24044E-5
11-1260788-G-T p.Gly1195Val missense MUC5B 15 82348 1.82154E-4 41174 0 6.37714E-5
11-1261048-A-G p.Pro1204Pro synonymous MUC5B 2 82060 2.43724E-5 41030 0 NA
11-1261066-C-A p.Phe1210Leu missense MUC5B 1 82218 1.21628E-5 41109 0 NA
11-1261068-A-G p.Asn1211Ser missense MUC5B 1 82220 1.21625E-5 41110 0 6.77376E-5
11-1261073-G-A p.Asp1213Asn missense MUC5B 1 82242 1.21592E-5 41121 0 NA
11-1261087-C-T p.Cys1217Cys synonymous MUC5B 1 82246 1.21586E-5 41123 0 1.21524E-5
11-1261088-G-A p.Val1218Met missense MUC5B 3 82256 3.64715E-5 41128 0 5.03525E-4
11-1261093-C-T p.Ala1219Ala synonymous MUC5B 4 82256 4.86287E-5 41128 0 1.61899E-5
11-1261099-T-C p.Cys1221Cys synonymous MUC5B 2 82254 2.43149E-5 41127 0 NA
11-1261105-C-T p.Cys1223Cys synonymous MUC5B 1 82198 1.21657E-5 41099 0 9.13759E-6
11-1261106-TACG-T p.Asp1225del conservative_inframe_deletion MUC5B 1 82218 1.21628E-5 41109 0 9.07985E-6
11-1261108-C-T p.Tyr1224Tyr synonymous MUC5B 5 82218 6.08139E-5 41109 0 0.00100705
11-1261110-A-T p.Asp1225Val missense MUC5B 2 82224 2.43238E-5 41112 0 6.37999E-5
11-1261118-G-A p.Gly1228Arg missense MUC5B 1 82246 1.21586E-5 41123 0 3.18898E-5
11-1261120-A-G p.Gly1228Gly synonymous MUC5B 3 82240 3.64786E-5 41120 0 2.66558E-5
11-1261125-A-C p.Tyr1230Ser missense MUC5B 3 82248 3.64751E-5 41124 0 7.2692E-5
11-1261127-T-A p.Tyr1231Asn missense MUC5B 1 82246 1.21586E-5 41123 0 NA
11-1261132-C-T p.Asp1232Asp synonymous MUC5B 8 82226 9.72928E-5 41113 0 9.29376E-5
11-1261133-G-A p.Val1233Ile missense MUC5B 24 82216 2.91914E-4 41108 0 5.04032E-4
11-1261135-C-T p.Val1233Val synonymous MUC5B 6 82200 7.29927E-5 41100 1 6.38325E-5
11-1261136-G-A p.Gly1234Ser missense MUC5B 2 82206 2.43291E-5 41103 0 7.05878E-5
11-1261140-C-G p.Ala1235Gly missense MUC5B 1 82182 1.21681E-5 41091 0 4.40366E-5
11-1261146-T-TC p.Thr1239fs frameshift MUC5B 1 82146 1.21734E-5 41073 0 NA
11-1261150-C-T p.Pro1238Pro synonymous MUC5B 2 82180 2.43368E-5 41090 0 1.40724E-4
11-1261156-G-A p.Ala1240Ala synonymous MUC5B 3 82166 3.65115E-5 41083 0 5.03525E-4
11-1261177-A-AG c.3737+4_3737+5insG splice_region MUC5B 1 82036 1.21898E-5 41018 0 NA
11-1261270-C-T c.3738-5C>T splice_region MUC5B 2 81826 2.44421E-5 40913 0 1.36267E-5
11-1261302-C-T p.Cys1255Cys synonymous MUC5B 5 81900 6.10501E-5 40950 0 2.83217E-5
11-1261302-C-G p.Cys1255Trp missense MUC5B 1 81900 1.221E-5 40950 0 NA
11-1261303-G-A p.Ala1256Thr missense MUC5B 1 81892 1.22112E-5 40946 0 4.73673E-5
11-1261311-C-T p.Ser1258Ser synonymous MUC5B 205 81946 0.00250165 40973 0 0.00587372
11-1261314-T-G p.Leu1259Leu synonymous MUC5B 1 81952 1.22023E-5 40976 0 6.57666E-5
11-1261401-T-C c.3782-7T>C splice_region MUC5B 3 82046 3.65649E-5 41023 0 NA
11-1261419-A-G p.Thr1265Ala missense MUC5B 1 82130 1.21758E-5 41065 0 2.04477E-5
11-1261427-G-A p.Glu1267Glu synonymous MUC5B 1 82198 1.21657E-5 41099 0 NA
11-1261434-A-C p.Thr1270Pro missense MUC5B 11 82204 1.33813E-4 41102 0 5.65652E-5
11-1261452-G-A p.Val1276Ile missense MUC5B 1 82282 1.21533E-5 41141 0 3.21973E-5
11-1261457-C-A p.Ile1277Ile synonymous MUC5B 3 82324 3.64414E-5 41162 0 6.37918E-5
11-1261458-TACA-T p.Asn1279del disruptive_inframe_deletion MUC5B 1 82316 1.21483E-5 41158 0 NA
11-1261469-C-T p.Thr1281Thr synonymous MUC5B 543 82338 0.00659477 41169 9 0.0156093
11-1261478-T-C p.Leu1284Leu synonymous MUC5B 2 82360 2.42836E-5 41180 0 4.01703E-6
11-1261481-C-T p.Gly1285Gly synonymous MUC5B 55 82348 6.67897E-4 41174 0 7.03167E-4
11-1261482-G-A p.Ala1286Thr missense MUC5B 1 82352 1.2143E-5 41176 0 1.66697E-5
11-1261493-C-T p.Ile1289Ile synonymous MUC5B 1 82368 1.21406E-5 41184 0 6.25E-4
11-1261494-G-A p.Ala1290Thr missense MUC5B 9 82348 1.09292E-4 41174 0 9.56633E-5
11-1261498-T-C p.Ile1291Thr missense MUC5B 3 82370 3.6421E-5 41185 0 8.31449E-6
11-1261502-C-T p.Cys1292Cys synonymous MUC5B 3 82320 3.64431E-5 41160 0 3.32607E-5
11-1261503-G-A p.Gly1293Arg missense MUC5B 1 82328 1.21465E-5 41164 0 4.1569E-5
11-1261506-A-C p.Ser1294Arg missense MUC5B 1 82332 1.21459E-5 41166 0 NA
11-1261511-C-T p.Asn1295Asn synonymous MUC5B 83 82300 0.00100851 41150 0 0.00184902
11-1261517-C-G p.Thr1297Thr synonymous MUC5B 2 82314 2.42972E-5 41157 0 2.49314E-5
11-1261519-T-G p.Ile1298Ser missense MUC5B 2 82320 2.42954E-5 41160 0 4.016E-5
11-1261520-C-G p.Ile1298Met missense MUC5B 19 82308 2.3084E-4 41154 0 6.05713E-4
11-1261529-G-A p.Lys1301Lys synonymous MUC5B 1 82274 1.21545E-5 41137 0 NA
11-1261530-G-A p.Ala1302Thr missense MUC5B 1 82244 1.21589E-5 41122 0 4.0181E-6
11-1261537-C-A p.Ala1304Glu missense MUC5B 5 82202 6.08258E-5 41101 0 2.81344E-5
11-1261542-C-T p.Pro1306Ser missense MUC5B 6 82186 7.30051E-5 41093 0 1.27567E-4
11-1261549-C-T p.Thr1308Ile missense MUC5B 1 82128 1.21761E-5 41064 0 NA
11-1261561-C-T p.Thr1312Met missense MUC5B 19 82184 2.31189E-4 41092 1 0.00100705
11-1261561-C-A p.Thr1312Lys missense MUC5B 1 82184 1.21678E-5 41092 0 NA
11-1261562-G-T p.Thr1312Thr synonymous MUC5B 1 82148 1.21732E-5 41074 0 NA
11-1261563-C-T p.Pro1313Ser missense MUC5B 289 82138 0.00351847 41069 5 0.00771782
11-1261580-C-T p.Thr1318Thr synonymous MUC5B 231 81986 0.00281755 40993 1 0.00589923
11-1261581-G-A p.Ala1319Thr missense MUC5B 1 81964 1.22005E-5 40982 0 1.23081E-5
11-1261588-T-C p.Val1321Ala missense MUC5B 1 81880 1.2213E-5 40940 0 NA
11-1261590-C-A p.Pro1322Thr missense MUC5B 4 81888 4.88472E-5 40944 1 0.0025
11-1261591-C-T p.Pro1322Leu missense MUC5B 2 81890 2.4423E-5 40945 0 6.37471E-5
11-1261595-C-A p.His1323Gln missense MUC5B 1 81852 1.22172E-5 40926 0 4.17484E-6
11-1261600-C-T p.Thr1325Met missense MUC5B 8 81810 9.77876E-5 40905 0 3.79318E-5
11-1262074-C-T c.3980-7C>T splice_region MUC5B 3 80084 3.74607E-5 40042 0 8.14374E-5
11-1262081-G-T p.Ser1327Ile missense+splice_region MUC5B 1 80172 1.24732E-5 40086 0 3.18857E-5
11-1262084-C-T p.Pro1328Leu missense MUC5B 145 80264 0.00180654 40132 0 0.00213436
11-1262088-C-A p.Ala1329Ala synonymous MUC5B 2 80396 2.48769E-5 40198 0 4.16788E-6
11-1262093-C-T p.Pro1331Leu missense MUC5B 8 80498 9.93814E-5 40249 0 1.15558E-4
11-1262093-C-G p.Pro1331Arg missense MUC5B 6 80498 7.4536E-5 40249 0 6.65386E-5