Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
10-45869713-C-G c.-15C>G 5_prime_UTR_premature_start_codon_gain ALOX5 10902 73986 0.147352 36993 733 0.193878
10-45869715-C-T c.-13C>T 5_prime_UTR_premature_start_codon_gain ALOX5 152 74910 0.0020291 37455 0 0.00316314
10-45869722-C-T c.-6C>T 5_prime_UTR_premature_start_codon_gain ALOX5 1 75356 1.32703E-5 37678 0 1.094E-5
10-45869731-C-T p.Pro2Ser missense ALOX5 1 76250 1.31148E-5 38125 0 6.43501E-5
10-45869731-C-A p.Pro2Thr missense ALOX5 1 76250 1.31148E-5 38125 0 NA
10-45869732-C-T p.Pro2Leu missense ALOX5 1 76350 1.30976E-5 38175 0 NA
10-45869733-C-T p.Pro2Pro synonymous ALOX5 1 76640 1.3048E-5 38320 0 1.27673E-4
10-45869742-G-C p.Thr5Thr synonymous ALOX5 2 76860 2.60213E-5 38430 0 1.7665E-5
10-45869747-C-T p.Thr7Ile missense ALOX5 1 77076 1.29742E-5 38538 0 NA
10-45869748-C-T p.Thr7Thr synonymous ALOX5 11493 76698 0.149847 38349 942 0.198204
10-45869757-T-G p.Thr10Thr synonymous ALOX5 3 77342 3.87888E-5 38671 0 NA
10-45869775-C-T p.Ala16Ala synonymous ALOX5 4 77616 5.15358E-5 38808 0 1.56299E-4
10-45869775-C-A p.Ala16Ala synonymous ALOX5 6 77614 7.73056E-5 38807 0 NA
10-45869784-C-T p.Asp19Asp synonymous ALOX5 1 77734 1.28644E-5 38867 0 7.2042E-6
10-45869791-A-G p.Ile22Val missense ALOX5 19 77860 2.44028E-4 38930 0 3.7154E-4
10-45869801-G-A p.Ser25Asn missense ALOX5 2 77946 2.56588E-5 38973 0 NA
10-45869802-C-T p.Ser25Ser synonymous ALOX5 1 77942 1.28301E-5 38971 0 6.76782E-6
10-45869809-G-A p.Gly28Ser missense ALOX5 2 77934 2.56627E-5 38967 0 6.40295E-6
10-45869817-G-T p.Ala30Ala synonymous ALOX5 1 77918 1.2834E-5 38959 0 NA
10-45869817-G-A p.Ala30Ala synonymous ALOX5 1 77918 1.2834E-5 38959 0 0.00154162
10-45869818-G-A p.Gly31Ser missense ALOX5 1 77918 1.2834E-5 38959 0 3.06628E-5
10-45869819-G-A p.Gly31Asp missense ALOX5 2 77888 2.56779E-5 38944 0 1.22834E-5
10-45869825-G-C p.Ser33Thr missense ALOX5 4 77836 5.13901E-5 38918 0 5.35045E-4
10-45869835-C-T p.His36His synonymous ALOX5 3 77930 3.84961E-5 38965 0 NA
10-45869838-G-C p.Leu37Leu synonymous ALOX5 1 77902 1.28366E-5 38951 0 NA
10-45869840-TGGACAA-T p.Asp39_Lys40del conservative_inframe_deletion ALOX5 1 77920 1.28337E-5 38960 0 NA
10-45869847-G-A p.Lys40Lys synonymous ALOX5 1 77920 1.28337E-5 38960 0 NA
10-45869864-T-TCGAGCGTGGCGCGGTGAGCG p.Gly31fs frameshift ALOX5 2 77742 2.57261E-5 38871 0 NA
10-45869871-TGGCGCGGTG-T p.Gly49_Ala50del splice_donor ALOX5 1 77568 1.28919E-5 38784 0 NA
10-45869880-G-A c.150+3G>A splice_region ALOX5 1 77410 1.29182E-5 38705 0 3.19509E-5
10-45877942-C-T p.Tyr54Tyr synonymous ALOX5 2 83246 2.40252E-5 41623 0 5.03525E-4
10-45877943-G-A p.Asp55Asn missense ALOX5 2 83256 2.40223E-5 41628 0 3.18451E-5
10-45877945-C-T p.Asp55Asp synonymous ALOX5 1 83254 1.20114E-5 41627 0 2.47288E-5
10-45877946-G-A p.Val56Met missense ALOX5 6 83256 7.20669E-5 41628 0 2.22887E-4
10-45877957-C-T p.Asp59Asp synonymous ALOX5 2 83268 2.40188E-5 41634 0 1.59057E-5
10-45877958-G-A p.Glu60Lys missense ALOX5 2 83270 2.40183E-5 41635 0 1.27429E-4
10-45877967-G-T p.Gly63Cys missense ALOX5 1 83284 1.20071E-5 41642 0 1.64826E-5
10-45877969-C-T p.Gly63Gly synonymous ALOX5 1 83280 1.20077E-5 41640 0 5.03525E-4
10-45877975-C-G p.Ile65Met missense ALOX5 2 83284 2.40142E-5 41642 0 NA
10-45877978-G-A p.Gln66Gln synonymous ALOX5 1 83286 1.20068E-5 41643 0 1.64842E-5
10-45877981-G-A p.Leu67Leu synonymous ALOX5 2 83286 2.40136E-5 41643 0 3.97662E-6
10-45877990-C-T p.Ile70Ile synonymous ALOX5 1 83270 1.20091E-5 41635 0 1.19304E-5
10-45877998-G-A p.Arg73His missense ALOX5 3 83268 3.60282E-5 41634 0 6.37024E-5
10-45878017-C-T p.Asp79Asp synonymous ALOX5 41 83238 4.92563E-4 41619 0 0.00151057
10-45878018-G-A p.Asp80Asn missense ALOX5 2 83228 2.40304E-5 41614 0 5.03525E-4
10-45878019-A-G p.Asp80Gly missense ALOX5 1 83230 1.20149E-5 41615 0 3.57961E-5
10-45878027-C-T p.Leu83Leu synonymous ALOX5 2 83248 2.40246E-5 41624 0 3.18451E-5
10-45878031-A-G p.Lys84Arg missense ALOX5 3 83244 3.60386E-5 41622 0 NA
10-45878032-G-A p.Lys84Lys synonymous ALOX5 3 83238 3.60412E-5 41619 0 5.03525E-4
10-45878036-A-G p.Ile86Val missense ALOX5 2 83224 2.40315E-5 41612 0 3.31345E-5
10-45878040-C-T p.Thr87Met missense ALOX5 1 83214 1.20172E-5 41607 0 3.1839E-5
10-45878049-C-T p.Thr90Met missense ALOX5 1 83172 1.20233E-5 41586 0 4.77566E-5
10-45878050-G-A p.Thr90Thr synonymous ALOX5 3770 83074 0.0453812 41537 387 0.0898572
10-45878056-C-T p.His92His synonymous ALOX5 2 83154 2.40518E-5 41577 0 6.36821E-5
10-45878057-G-A p.Gly93Arg missense ALOX5 1 83156 1.20256E-5 41578 0 8.40661E-6
10-45878058-G-A p.Gly93Glu missense ALOX5 1 83158 1.20253E-5 41579 0 NA
10-45878065-C-T p.Tyr95Tyr synonymous ALOX5 1 83122 1.20305E-5 41561 0 NA
10-45878085-G-A p.Arg102His missense ALOX5 1 83012 1.20465E-5 41506 0 6.25E-4
10-45878095-C-T p.Thr105Thr synonymous ALOX5 7 82944 8.43943E-5 41472 0 1.27389E-4
10-45878096-G-A p.Gly106Ser missense ALOX5 13 82924 1.5677E-4 41462 0 6.25E-4
10-45878098-C-T p.Gly106Gly synonymous ALOX5 29 82918 3.49743E-4 41459 0 9.91426E-4
10-45878099-G-A p.Asp107Asn missense ALOX5 3 82914 3.61821E-5 41457 0 7.99968E-6
10-45878105-G-A p.Glu109Lys missense ALOX5 8 82808 9.6609E-5 41404 0 0.00125
10-45878108-G-C p.Val110Leu missense ALOX5 1 82778 1.20805E-5 41389 0 NA
10-45878128-C-T p.Arg116Arg splice_region+synonymous ALOX5 2 82352 2.4286E-5 41176 0 1.2304E-5
10-45878129-G-A p.Ala117Thr missense+splice_region ALOX5 3 82308 3.64485E-5 41154 0 8.21564E-6
10-45878137-G-T c.349+8G>T splice_region ALOX5 1 82122 1.2177E-5 41061 0 4.16524E-6
10-45891300-C-T c.350-3C>T splice_region ALOX5 2 83316 2.4005E-5 41658 0 NA
10-45891307-G-T p.Lys118Asn missense ALOX5 1 83338 1.19993E-5 41669 0 1.64989E-5
10-45891311-G-T p.Ala120Ser missense ALOX5 6 83340 7.19942E-5 41670 0 1.56704E-4
10-45891314-C-T p.Arg121* stop_gained ALOX5 2 83338 2.39987E-5 41669 0 8.2462E-6
10-45891315-G-C p.Arg121Pro missense ALOX5 1 83344 1.19985E-5 41672 0 4.77194E-5
10-45891315-G-A p.Arg121Gln missense ALOX5 1 83344 1.19985E-5 41672 0 6.25E-4
10-45891322-C-T p.Asp123Asp synonymous ALOX5 2 83346 2.39964E-5 41673 0 1.5906E-5
10-45891332-A-C p.Ile127Leu missense ALOX5 1 83354 1.1997E-5 41677 0 NA
10-45891344-C-T p.His131Tyr missense ALOX5 2 83344 2.39969E-5 41672 0 1.64861E-5
10-45891350-C-T p.Arg133Cys missense ALOX5 7 83356 8.39772E-5 41678 0 5.68847E-4
10-45891351-G-A p.Arg133His missense ALOX5 3 83358 3.59893E-5 41679 0 9.55171E-5
10-45891358-A-G p.Glu135Glu synonymous ALOX5 1 83354 1.1997E-5 41677 0 1.64919E-5
10-45891359-C-G p.Leu136Val missense ALOX5 1 83352 1.19973E-5 41676 0 NA
10-45891367-A-T p.Thr138Thr synonymous ALOX5 2 83354 2.3994E-5 41677 0 NA
10-45891368-C-T p.Arg139Trp missense ALOX5 9 83352 1.07976E-4 41676 0 1.35213E-4
10-45891371-C-CA p.Gln142fs frameshift ALOX5 1 83354 1.1997E-5 41677 0 NA
10-45891375-A-G p.Lys141Arg missense ALOX5 3 83350 3.59928E-5 41675 0 1.65218E-5
10-45891376-A-G p.Lys141Lys synonymous ALOX5 3 83346 3.59945E-5 41673 0 5.03525E-4
10-45891379-A-G p.Gln142Gln synonymous ALOX5 3 83336 3.59988E-5 41668 0 4.37459E-5
10-45891384-G-A p.Arg144Gln missense+splice_region ALOX5 4 83330 4.80019E-5 41665 0 3.1841E-5
10-45891387-G-A c.431+3G>A splice_region ALOX5 4 83330 4.80019E-5 41665 0 3.1837E-5
10-45891389-G-C c.431+5G>C splice_region ALOX5 1 83308 1.20036E-5 41654 0 NA
10-45907636-CAGAT-C p.Trp145fs frameshift ALOX5 3 83374 3.59824E-5 41687 0 1.64902E-5
10-45907639-A-G p.Arg144Arg splice_region+synonymous ALOX5 1 83392 1.19916E-5 41696 0 1.64867E-5
10-45907643-A-G p.Met146Val missense ALOX5 1 83392 1.19916E-5 41696 0 3.97766E-6
10-45907675-C-T p.Ile156Ile synonymous ALOX5 5 83408 5.99463E-5 41704 0 7.96483E-4
10-45907678-T-A p.Asp157Glu missense ALOX5 1 83410 1.1989E-5 41705 0 1.59058E-5
10-45907679-G-A p.Ala158Thr missense ALOX5 1 83410 1.1989E-5 41705 0 3.97655E-6
10-45907704-G-A p.Arg166His missense ALOX5 1 83404 1.19898E-5 41702 0 8.23791E-6
10-45907711-C-A p.Ile168Ile synonymous ALOX5 1 83404 1.19898E-5 41702 0 8.23791E-6
10-45907716-T-C p.Phe170Ser missense ALOX5 1 83402 1.19901E-5 41701 0 NA
10-45907753-C-T p.Tyr182Tyr synonymous ALOX5 1 83368 1.1995E-5 41684 0 8.24906E-6
10-45919484-T-A c.555-5T>A splice_region ALOX5 4 83208 4.80723E-5 41604 0 8.25873E-6
10-45919485-G-A c.555-4G>A splice_region ALOX5 4 83218 4.80665E-5 41609 0 NA
10-45919500-T-C p.Leu189Pro missense ALOX5 1 83316 1.20025E-5 41658 0 NA
10-45919504-C-G p.Phe190Leu missense ALOX5 17 83324 2.04023E-4 41662 0 1.19309E-5
10-45919509-A-G p.Asn192Ser missense ALOX5 1 83336 1.19996E-5 41668 0 3.97655E-6
10-45919520-C-T p.His196Tyr missense ALOX5 1 83340 1.1999E-5 41670 0 NA
10-45919524-T-C p.Met197Thr missense ALOX5 1 83346 1.19982E-5 41673 0 3.18552E-5
10-45919536-C-G p.Ser201Cys missense ALOX5 2 83352 2.39946E-5 41676 0 1.64766E-5
10-45919549-C-T p.Phe205Phe synonymous ALOX5 2 83336 2.39992E-5 41668 0 0.00100705
10-45919550-G-A p.Ala206Thr missense ALOX5 7 83328 8.40054E-5 41664 0 3.97659E-5
10-45919552-C-T p.Ala206Ala synonymous ALOX5 14 83330 1.68007E-4 41665 0 2.54793E-4
10-45919553-G-A p.Asp207Asn missense ALOX5 1 83334 1.19999E-5 41667 0 2.47182E-5
10-45919567-CT-C p.Phe212fs frameshift ALOX5 1 83312 1.20031E-5 41656 0 NA
10-45919571-G-A p.Val213Ile missense ALOX5 2 83286 2.40136E-5 41643 0 3.18573E-5
10-45919584-A-G p.Asn217Ser missense ALOX5 1 83228 1.20152E-5 41614 0 4.12541E-5
10-45919586-A-G p.Thr218Ala missense ALOX5 23 83234 2.76329E-4 41617 0 6.25E-4
10-45919598-G-C c.661+3G>C splice_region ALOX5 1 83132 1.20291E-5 41566 0 NA
10-45919603-T-G c.661+8T>G splice_region ALOX5 1 83072 1.20378E-5 41536 0 8.26747E-6
10-45920403-G-A c.662-5G>A splice_region ALOX5 1 82750 1.20846E-5 41375 0 NA
10-45920410-C-A p.Arg222Arg splice_region+synonymous ALOX5 1 82850 1.207E-5 41425 0 NA
10-45920411-G-A p.Arg222Gln missense ALOX5 3 82836 3.62161E-5 41418 0 6.25E-4
10-45920412-G-T p.Arg222Arg synonymous ALOX5 1 82872 1.20668E-5 41436 0 NA
10-45920420-A-G p.Asn225Ser missense ALOX5 1 82948 1.20557E-5 41474 0 2.47435E-5
10-45920430-G-A p.Gln228Gln synonymous ALOX5 1 82978 1.20514E-5 41489 0 NA
10-45920434-G-A p.Asp230Asn missense ALOX5 2 82984 2.4101E-5 41492 0 NA
10-45920438-T-G p.Leu231Arg missense ALOX5 1 83024 1.20447E-5 41512 0 NA
10-45920440-A-T p.Met232Leu missense ALOX5 1 83052 1.20406E-5 41526 0 7.95431E-6
10-45920453-A-G p.Gln236Arg missense ALOX5 1 83132 1.20291E-5 41566 0 NA
10-45920457-C-T p.Phe237Phe synonymous ALOX5 4 83148 4.8107E-5 41574 0 2.38635E-5
10-45920485-C-T p.Arg247Trp missense ALOX5 2 83192 2.40408E-5 41596 0 1.28189E-4
10-45920486-G-A p.Arg247Gln missense ALOX5 4 83184 4.80862E-5 41592 0 4.11862E-5
10-45920489-G-A p.Arg248His missense ALOX5 1 83202 1.20189E-5 41601 0 3.18776E-5
10-45920506-G-A p.Glu254Lys missense ALOX5 958 83216 0.0115122 41608 39 0.0265473
10-45920517-G-A p.Pro257Pro synonymous ALOX5 18 83248 2.16221E-4 41624 0 8.24729E-5
10-45920526-G-A p.Thr260Thr synonymous ALOX5 44 83262 5.28452E-4 41631 1 0.005
10-45920539-T-C p.Cys265Arg missense ALOX5 1 83242 1.20132E-5 41621 0 2.7874E-5
10-45920551-C-A p.Arg269Arg synonymous ALOX5 1 83260 1.20106E-5 41630 0 NA
10-45920552-G-A p.Arg269Gln missense ALOX5 3 83264 3.603E-5 41632 0 1.67325E-5
10-45920554-C-G p.Gln270Glu missense ALOX5 1 83262 1.20103E-5 41631 0 NA
10-45920559-C-T p.Leu271Leu synonymous ALOX5 6 83236 7.20842E-5 41618 0 3.18532E-5
10-45924081-A-G p.Ile284Val missense ALOX5 1 82882 1.20653E-5 41441 0 NA
10-45924083-C-G p.Ile284Met missense ALOX5 1 82900 1.20627E-5 41450 0 3.98578E-6
10-45924086-G-A p.Val285Val synonymous ALOX5 20 82920 2.41196E-4 41460 0 4.46059E-4
10-45924088-A-G p.Asp286Gly missense ALOX5 1 82928 1.20587E-5 41464 0 7.96851E-6
10-45924092-T-C p.Phe287Phe synonymous ALOX5 1 82966 1.20531E-5 41483 0 8.24824E-6
10-45924098-G-A p.Leu289Leu synonymous ALOX5 4 83000 4.81928E-5 41500 0 5.974E-5
10-45924108-A-G p.Ile293Val missense ALOX5 1 83104 1.20331E-5 41552 0 3.18634E-5
10-45924119-C-T p.Asn296Asn synonymous ALOX5 2 83178 2.40448E-5 41589 0 3.18613E-5
10-45924123-A-C p.Thr298Pro missense ALOX5 1 83184 1.20215E-5 41592 0 NA
10-45924128-C-A p.Asp299Glu missense ALOX5 1 83190 1.20207E-5 41595 0 7.42182E-5
10-45924140-C-A p.Leu303Leu synonymous ALOX5 2 83180 2.40442E-5 41590 0 3.97864E-6
10-45924152-C-A p.Ala307Ala synonymous ALOX5 4 83136 4.81139E-5 41568 0 3.97902E-6
10-45924153-G-A p.Ala308Thr missense ALOX5 3 83132 3.60872E-5 41566 0 3.58132E-5
10-45924179-C-T p.Asn316Asn synonymous ALOX5 1 83048 1.20412E-5 41524 0 1.64935E-5
10-45924179-C-G p.Asn316Lys missense ALOX5 1 83048 1.20412E-5 41524 0 NA
10-45924188-C-T p.Asn319Asn synonymous ALOX5 1 82960 1.2054E-5 41480 0 8.24824E-6
10-45924202-T-C p.Ile324Thr missense ALOX5 2 82682 2.41891E-5 41341 0 8.25082E-6
10-45924211-A-AGCTCAACCAAATCCC p.Leu312delinsPheSerThrLysSerArg disruptive_inframe_insertion ALOX5 1 82460 1.21271E-5 41230 0 NA
10-45924220-G-C c.981+8G>C splice_region ALOX5 5 82002 6.09741E-5 41001 0 1.59317E-4
10-45935870-T-C c.982-8T>C splice_region ALOX5 3 83356 3.59902E-5 41678 0 7.96235E-6
10-45935882-A-G p.Asn329Ser missense ALOX5 14 83378 1.6791E-4 41689 0 3.8236E-4
10-45935891-C-T p.Pro332Leu missense ALOX5 1 83384 1.19927E-5 41692 0 3.97864E-6
10-45935892-G-A p.Pro332Pro synonymous ALOX5 47 83382 5.63671E-4 41691 0 5.09587E-4
10-45935897-A-G p.Asp334Gly missense ALOX5 1 83386 1.19924E-5 41693 0 1.19325E-5
10-45935898-T-C p.Asp334Asp synonymous ALOX5 1 83388 1.19921E-5 41694 0 3.97741E-6
10-45935899-G-A p.Glu335Lys missense ALOX5 3 83390 3.59755E-5 41695 0 3.57967E-5
10-45935905-C-T p.Pro337Ser missense ALOX5 26 83390 3.11788E-4 41695 0 8.91436E-4
10-45935918-C-T p.Pro341Leu missense ALOX5 1 83398 1.19907E-5 41699 0 8.23832E-6
10-45935921-C-T p.Ser342Leu missense ALOX5 1 83394 1.19913E-5 41697 0 3.97684E-6
10-45935922-G-A p.Ser342Ser synonymous ALOX5 1 83392 1.19916E-5 41696 0 1.98831E-5
10-45935934-C-T p.Tyr346Tyr synonymous ALOX5 2 83400 2.39808E-5 41700 0 6.36902E-5
10-45935935-G-A p.Asp347Asn missense ALOX5 1 83400 1.19904E-5 41700 0 7.95305E-6
10-45935956-T-C p.Trp354Arg missense ALOX5 1 83398 1.19907E-5 41699 0 3.9764E-6
10-45935962-C-T p.Arg356Cys missense ALOX5 1 83396 1.1991E-5 41698 0 8.23696E-6
10-45935963-G-A p.Arg356His missense ALOX5 3 83398 3.59721E-5 41699 0 5.76606E-5
10-45935977-C-G p.His361Asp missense ALOX5 1 83398 1.19907E-5 41699 0 3.18471E-5
10-45935980-G-A p.Val362Ile missense ALOX5 6 83394 7.19476E-5 41697 0 2.78357E-5
10-45935986-C-T p.Gln364* stop_gained ALOX5 1 83398 1.19907E-5 41699 0 NA
10-45936002-T-A p.Leu369His missense ALOX5 2 83394 2.39825E-5 41697 0 NA
10-45936004-C-T p.Leu370Leu synonymous ALOX5 1 83390 1.19918E-5 41695 0 3.97671E-6
10-45936011-C-T p.Thr372Ile missense ALOX5 2 83376 2.39877E-5 41688 0 6.37024E-5
10-45936022-T-A p.Ser376Thr missense ALOX5 3 83370 3.59842E-5 41685 0 2.78381E-5
10-45936025-G-C p.Glu377Gln missense ALOX5 2 83368 2.399E-5 41684 0 8.24484E-6
10-45936027-G-A p.Glu377Glu synonymous ALOX5 3 83366 3.59859E-5 41683 0 NA
10-45936039-T-A p.Ile381Ile synonymous ALOX5 2 83342 2.39975E-5 41671 0 8.25709E-6
10-45936049-C-T p.Arg385Cys missense ALOX5 1 83310 1.20034E-5 41655 0 3.18715E-5
10-45936050-G-A p.Arg385His missense ALOX5 1 83302 1.20045E-5 41651 0 2.3866E-5
10-45936061-G-A p.Ala389Thr missense ALOX5 1 83250 1.2012E-5 41625 0 3.97848E-6
10-45936066-G-A p.Val390Val synonymous ALOX5 1 83220 1.20163E-5 41610 0 8.37703E-6
10-45936072-C-T p.Pro392Pro synonymous ALOX5 1 83174 1.2023E-5 41587 0 NA
10-45936079-A-G p.Lys395Glu missense+splice_region ALOX5 2 83134 2.40575E-5 41567 0 NA
10-45936807-G-A p.Val401Met missense ALOX5 4 82908 4.82462E-5 41454 0 3.98054E-5
10-45936824-A-G p.Ala406Ala synonymous ALOX5 4 83122 4.8122E-5 41561 0 3.18372E-5
10-45936837-G-A p.Ala411Thr missense ALOX5 1 83168 1.20239E-5 41584 0 NA
10-45936840-C-T p.Arg412Cys missense ALOX5 3 83178 3.60672E-5 41589 0 1.64834E-5
10-45936846-C-T p.Gln414* stop_gained ALOX5 2 83216 2.40338E-5 41608 0 NA
10-45936857-C-T p.Cys417Cys synonymous ALOX5 1 83226 1.20155E-5 41613 0 8.24593E-6
10-45936866-C-G p.Gly420Gly synonymous ALOX5 4 83222 4.80642E-5 41611 0 2.80491E-4
10-45938493-C-A p.Ala427Asp missense ALOX5 1 82462 1.21268E-5 41231 0 8.53403E-6
10-45938504-G-A p.Gly431Ser missense ALOX5 1 82644 1.21001E-5 41322 0 NA
10-45938506-T-C p.Gly431Gly synonymous ALOX5 1 82688 1.20937E-5 41344 0 3.19224E-5
10-45938509-G-C p.Gly432Gly synonymous ALOX5 58 82740 7.00991E-4 41370 1 0.0011803
10-45938509-G-A p.Gly432Gly synonymous ALOX5 2 82740 2.41721E-5 41370 0 2.2637E-4
10-45938509-G-T p.Gly432Gly synonymous ALOX5 1 82740 1.20861E-5 41370 0 1.276E-4
10-45938514-T-G p.Val434Gly missense ALOX5 1 82830 1.20729E-5 41415 0 3.99329E-6
10-45938517-A-G p.Gln435Arg missense ALOX5 2 82866 2.41354E-5 41433 0 3.19061E-5
10-45938525-C-T p.Gln438* stop_gained ALOX5 1 82938 1.20572E-5 41469 0 NA
10-45938539-G-A p.Lys442Lys synonymous ALOX5 3 83008 3.61411E-5 41504 0 6.25E-4
10-45938539-GGACCTGACCTAT-G p.Asp443_Tyr446del disruptive_inframe_deletion ALOX5 1 83008 1.2047E-5 41504 0 NA
10-45938548-C-T p.Thr445Thr synonymous ALOX5 1 83032 1.20435E-5 41516 0 NA
10-45938552-G-T p.Ala447Ser missense ALOX5 1 83030 1.20438E-5 41515 0 6.37959E-5
10-45938560-G-C p.Leu449Leu synonymous ALOX5 1 83054 1.20404E-5 41527 0 NA
10-45938566-T-C p.Phe451Phe synonymous ALOX5 1 83050 1.20409E-5 41525 0 NA
10-45938567-C-T p.Pro452Ser missense ALOX5 2 83052 2.40813E-5 41526 0 2.48554E-5
10-45938578-C-G p.Ile455Met missense ALOX5 2 83068 2.40767E-5 41534 0 6.25E-4
10-45938581-G-A p.Lys456Lys synonymous ALOX5 1 83080 1.20366E-5 41540 0 NA
10-45938584-C-T p.Ala457Ala synonymous ALOX5 1 83080 1.20366E-5 41540 0 NA
10-45938585-C-T p.Arg458Trp missense ALOX5 1 83076 1.20372E-5 41538 0 3.98048E-6
10-45938596-G-A p.Glu461Glu synonymous ALOX5 3 83092 3.61046E-5 41546 0 NA
10-45938602-A-T p.Lys463Asn missense ALOX5 2 83102 2.40668E-5 41551 0 3.98035E-6
10-45938608-C-T p.Asp465Asp synonymous ALOX5 1 83106 1.20328E-5 41553 0 NA
10-45938616-A-G p.Tyr468Cys missense ALOX5 1 83060 1.20395E-5 41530 0 NA
10-45938617-C-T p.Tyr468Tyr synonymous ALOX5 2 83066 2.40772E-5 41533 0 6.37633E-5
10-45938618-T-C p.Tyr469His missense ALOX5 1 83046 1.20415E-5 41523 0 8.29339E-6
10-45938631-A-T p.Asp473Val missense ALOX5 1 82962 1.20537E-5 41481 0 NA
10-45938640-T-A p.Leu476His missense ALOX5 2 82888 2.41289E-5 41444 0 4.78354E-5
10-45938651-G-C p.Glu480Gln missense ALOX5 1 82818 1.20747E-5 41409 0 NA
10-45938664-C-T p.Thr484Met missense+splice_region ALOX5 1 82650 1.20992E-5 41325 0 6.38162E-5
10-45938667-G-A c.1451+3G>A splice_region ALOX5 1 82620 1.21036E-5 41310 0 NA
10-45938670-C-A c.1451+6C>A splice_region ALOX5 1 82496 1.21218E-5 41248 0 9.5816E-5
10-45938854-CCT-C c.1452-9_1452-8delCT splice_region ALOX5 5 80964 6.17558E-5 40482 0 5.40292E-5
10-45938859-GC-G c.1452-3delC splice_region ALOX5 1 80962 1.23515E-5 40481 0 NA
10-45938860-C-G c.1452-4C>G splice_region ALOX5 1 80956 1.23524E-5 40478 0 1.46768E-4
10-45938867-C-A p.Phe485Leu missense ALOX5 3 81094 3.69941E-5 40547 0 5.23081E-5
10-45938869-C-T p.Thr486Met missense ALOX5 3 81120 3.69822E-5 40560 0 NA
10-45938870-G-A p.Thr486Thr synonymous ALOX5 3 81142 3.69722E-5 40571 0 3.1955E-5
10-45938873-C-T p.Ala487Ala synonymous ALOX5 1 81146 1.23235E-5 40573 0 3.1955E-5
10-45938877-G-T p.Val489Leu missense ALOX5 3 81256 3.69204E-5 40628 0 NA
10-45938886-A-G p.Ile492Val missense ALOX5 2 81380 2.45761E-5 40690 0 1.59683E-4
10-45938891-C-T p.Tyr493Tyr synonymous ALOX5 1 81450 1.22775E-5 40725 0 1.14056E-5
10-45938897-G-A p.Glu495Glu synonymous ALOX5 1 81512 1.22681E-5 40756 0 3.19244E-5
10-45938898-G-A p.Gly496Ser missense ALOX5 4 81504 4.90773E-5 40752 0 6.38488E-5
10-45938907-G-A p.Val499Met missense ALOX5 2 81648 2.44954E-5 40824 0 3.19183E-5
10-45938909-G-A p.Val499Val synonymous ALOX5 2 81648 2.44954E-5 40824 0 NA
10-45938910-G-A p.Val500Met missense ALOX5 2 81636 2.4499E-5 40818 0 1.92567E-5
10-45938917-A-C p.Glu502Ala missense ALOX5 1 81644 1.22483E-5 40822 0 3.19448E-5
10-45938923-C-T p.Pro504Leu missense ALOX5 3 81648 3.67431E-5 40824 0 2.71769E-5
10-45938925-G-T p.Glu505* stop_gained ALOX5 1 81648 1.22477E-5 40824 0 NA
10-45938940-G-A p.Val510Met missense ALOX5 1 81526 1.2266E-5 40763 0 8.00711E-6
10-45938942-G-A p.Val510Val synonymous ALOX5 1 81530 1.22654E-5 40765 0 NA
10-45938944-A-G p.Asn511Ser missense ALOX5 2 81508 2.45375E-5 40754 0 8.60511E-6
10-45938952-T-C p.Tyr514His missense ALOX5 1 81326 1.22962E-5 40663 0 NA
10-45938954-C-T p.Tyr514Tyr synonymous ALOX5 1 81236 1.23098E-5 40618 0 NA
10-45938960-C-T p.Tyr516Tyr synonymous ALOX5 1 81076 1.23341E-5 40538 0 NA
10-45938964-A-T p.Met518Leu missense ALOX5 5 80972 6.17497E-5 40486 0 3.19795E-5
10-45938967-C-T p.Arg519Trp missense ALOX5 1 80844 1.23695E-5 40422 0 NA
10-45938968-G-A p.Arg519Gln missense ALOX5 2 80848 2.47378E-5 40424 0 NA
10-45938970-G-T p.Gly520Cys missense ALOX5 5 80804 6.18781E-5 40402 0 1.20737E-5
10-45938973-C-T p.Arg521Cys missense ALOX5 1 80700 1.23916E-5 40350 0 8.5887E-6
10-45938974-G-A p.Arg521His missense ALOX5 1 80644 1.24002E-5 40322 0 3.43944E-5
10-45938987-T-TTCCCCA c.1573+2_1573+3insTCCCCA splice_region ALOX5 1 80372 1.24421E-5 40186 0 NA
10-45938987-T-C c.1573+2T>C splice_donor ALOX5 1 80372 1.24421E-5 40186 0 8.66371E-6
10-45939188-C-G p.Ser529Trp missense ALOX5 1 80932 1.23561E-5 40466 0 NA
10-45939200-G-A p.Arg533Gln missense ALOX5 1 81212 1.23135E-5 40606 0 NA
10-45939210-G-T p.Leu536Leu synonymous ALOX5 1 81228 1.2311E-5 40614 0 3.19611E-5
10-45939212-C-T p.Ser537Leu missense ALOX5 1 81166 1.23204E-5 40583 0 NA
10-45939213-G-A p.Ser537Ser synonymous ALOX5 1 81180 1.23183E-5 40590 0 8.08806E-6
10-45939213-G-C p.Ser537Ser synonymous ALOX5 1 81180 1.23183E-5 40590 0 9.69537E-6
10-45939217-T-C p.Tyr539His missense ALOX5 1 81148 1.23232E-5 40574 0 NA
10-45939219-C-T p.Tyr539Tyr synonymous ALOX5 6 81214 7.38789E-5 40607 0 3.19591E-5
10-45939225-C-G p.Thr541Thr synonymous ALOX5 3 81148 3.69695E-5 40574 0 9.93285E-6
10-45939226-G-A p.Val542Met missense ALOX5 1 81114 1.23283E-5 40557 0 3.19489E-5
10-45939226-G-C p.Val542Leu missense ALOX5 1 81114 1.23283E-5 40557 0 NA
10-45939228-G-A p.Val542Val synonymous ALOX5 1 81098 1.23308E-5 40549 0 NA
10-45939252-G-A p.Gln550Gln synonymous ALOX5 1 80612 1.24051E-5 40306 0 NA
10-45939255-C-G p.His551Gln missense ALOX5 1 80532 1.24174E-5 40266 0 5.05051E-4
10-45939258-C-T p.Ala552Ala synonymous ALOX5 4 80420 4.97389E-5 40210 0 3.69996E-5
10-45939271-G-A p.Gly557Ser missense ALOX5 3 79898 3.75479E-5 39949 0 9.57182E-5
10-45939280-G-C c.1674+4G>C splice_region ALOX5 1 79640 1.25565E-5 39820 0 4.61174E-6
10-45939281-G-A c.1674+5G>A splice_region ALOX5 6 79556 7.54186E-5 39778 0 1.6839E-5
10-45939283-A-G c.1674+7A>G splice_region ALOX5 1 79492 1.25799E-5 39746 0 1.68486E-5
10-45939561-C-T c.1675-3C>T splice_region ALOX5 290 77936 0.003721 38968 4 0.00875
10-45939567-G-A p.Asp560Asn missense ALOX5 3 78192 3.83671E-5 39096 0 NA
10-45939569-C-T p.Asp560Asp synonymous ALOX5 2 78362 2.55226E-5 39181 0 1.62048E-4
10-45939587-C-G p.Pro566Pro synonymous ALOX5 1 79086 1.26445E-5 39543 0 3.18857E-5
10-45939594-C-T p.Pro569Ser missense ALOX5 1 79174 1.26304E-5 39587 0 NA
10-45939617-A-G p.Pro576Pro synonymous ALOX5 5579 79712 0.0699895 39856 228 0.096052
10-45939617-ACC-GCA p.ProPro576ProGln missense ALOX5 1 79812 1.25294E-5 39906 0 NA
10-45939620-G-A p.Pro577Pro synonymous ALOX5 1 79842 1.25247E-5 39921 0 6.11628E-6
10-45939633-G-A p.Val582Met missense ALOX5 3 79952 3.75225E-5 39976 0 5.21921E-4
10-45939637-T-G p.Val583Gly missense ALOX5 2 79970 2.50094E-5 39985 0 1.96309E-4
10-45939643-T-C p.Ile585Thr missense ALOX5 1 80064 1.249E-5 40032 0 NA
10-45939660-A-G p.Thr591Ala missense ALOX5 6 80000 7.5E-5 40000 0 3.18593E-5
10-45939661-C-T p.Thr591Met missense ALOX5 2 79998 2.50006E-5 39999 0 6.37267E-5
10-45939662-G-T n.604G>T splice_region ALOX5 3 79966 3.75159E-5 39983 0 NA
10-45939665-G-A p.Leu592Leu synonymous ALOX5 1 79908 1.25144E-5 39954 0 5.19859E-5
10-45939685-G-T p.Cys599Phe missense ALOX5 5 80078 6.24391E-5 40039 0 3.18512E-5
10-45939695-G-A p.Leu602Leu synonymous ALOX5 2 80122 2.49619E-5 40061 0 6.20794E-6
10-45939709-C-T p.Ala607Val missense ALOX5 1 79940 1.25094E-5 39970 0 6.37024E-5
10-45939716-C-G p.Ser609Arg missense ALOX5 1 79912 1.25138E-5 39956 0 6.24891E-6
10-45939731-C-A p.Asn614Lys missense ALOX5 1 79744 1.25401E-5 39872 0 1.13792E-4
10-45939742-T-C c.1845+8T>C splice_region ALOX5 1 79478 1.25821E-5 39739 0 6.4423E-6
10-45940969-T-C p.Met620Thr missense ALOX5 1 83332 1.20002E-5 41666 0 8.26078E-6
10-45940973-CC-TG p.TyrPro621TyrAla missense ALOX5 1 83330 1.20005E-5 41665 0 NA
10-45940975-C-T p.Pro622Leu missense ALOX5 1 83342 1.19988E-5 41671 0 NA
10-45940988-T-G p.Phe626Leu missense ALOX5 6 83342 7.19925E-5 41671 0 3.18114E-5
10-45940990-T-C p.Ile627Thr missense ALOX5 1 83346 1.19982E-5 41673 0 NA
10-45941020-G-A p.Arg637Gln missense ALOX5 2 83362 2.39917E-5 41681 0 1.64785E-5
10-45941025-C-T p.Arg639Cys missense ALOX5 1 83360 1.19962E-5 41680 0 4.1195E-5
10-45941026-G-A p.Arg639His missense ALOX5 1 83352 1.19973E-5 41676 0 8.23886E-6
10-45941026-G-T p.Arg639Leu missense ALOX5 1 83352 1.19973E-5 41676 0 NA
10-45941036-C-G p.Leu642Leu synonymous ALOX5 43 83354 5.15872E-4 41677 0 5.4147E-4
10-45941036-C-T p.Leu642Leu synonymous ALOX5 3 83354 3.59911E-5 41677 0 1.64775E-5
10-45941043-A-T p.Ile645Phe missense ALOX5 3 83358 3.59893E-5 41679 0 NA
10-45941044-T-C p.Ile645Thr missense ALOX5 1 83356 1.19967E-5 41678 0 8.23873E-6
10-45941048-C-G p.Val646Val synonymous ALOX5 4 83346 4.79927E-5 41673 0 1.63031E-4
10-45941048-C-T p.Val646Val synonymous ALOX5 2 83346 2.39964E-5 41673 0 1.64777E-5
10-45941050-G-T p.Ser647Ile missense ALOX5 3 83340 3.59971E-5 41670 0 9.55536E-5
10-45941052-G-A p.Val648Met missense ALOX5 20 83338 2.39987E-4 41669 0 1.59226E-4
10-45941054-G-A p.Val648Val synonymous ALOX5 1 83342 1.19988E-5 41671 0 1.19293E-5
10-45941058-G-A p.Ala650Thr missense ALOX5 4 83336 4.79985E-5 41668 0 3.9764E-5
10-45941064-C-A p.Arg652Ser missense ALOX5 3 83320 3.60058E-5 41660 0 9.56084E-5
10-45941065-G-A p.Arg652His missense ALOX5 3 83316 3.60075E-5 41658 0 6.59207E-5
10-45941065-G-GC p.Asn653fs frameshift ALOX5 1 83316 1.20025E-5 41658 0 NA
10-45941069-C-G p.Asn653Lys missense ALOX5 1 83322 1.20016E-5 41661 0 7.95311E-6
10-45941076-A-C p.Lys656Gln missense ALOX5 101 83328 0.00121208 41664 0 0.005
10-45941087-A-G p.Pro659Pro synonymous ALOX5 1 83320 1.20019E-5 41660 0 NA
10-45941109-C-T p.Arg667Trp missense ALOX5 1 83228 1.20152E-5 41614 0 3.57984E-5
10-45941109-C-G p.Arg667Gly missense ALOX5 1 83228 1.20152E-5 41614 0 NA
10-45941110-G-A p.Arg667Gln missense ALOX5 1 83220 1.20163E-5 41610 0 3.30568E-5
10-45941117-G-A p.Pro669Pro synonymous ALOX5 6 83170 7.21414E-5 41585 0 9.93229E-5
10-45941123-T-C p.Ser671Ser synonymous ALOX5 1 83102 1.20334E-5 41551 0 NA