Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
20-4202196-T-C p.Ser565Gly missense ADRA1D 2 83006 2.40946E-5 41503 0 NA
20-4202202-C-A p.Asp563Tyr missense ADRA1D 2 82924 2.41185E-5 41462 0 7.62531E-5
20-4202223-A-C p.Cys556Gly missense ADRA1D 1 82712 1.20901E-5 41356 0 NA
20-4202228-G-C p.Ala554Gly missense ADRA1D 8 82570 9.68875E-5 41285 0 3.223E-5
20-4202235-C-T p.Glu552Lys missense ADRA1D 2 82474 2.42501E-5 41237 0 3.18593E-5
20-4202244-C-G p.Glu549Gln missense ADRA1D 2 82190 2.43339E-5 41095 0 2.01851E-5
20-4202244-C-A p.Glu549* stop_gained ADRA1D 1 82190 1.21669E-5 41095 0 NA
20-4202271-C-T p.Glu540Lys missense ADRA1D 1 81384 1.22874E-5 40692 0 8.11116E-6
20-4202273-ACCTCTGAGCGCTGGGCGCACGCTG-A p.Ala531_Glu538del disruptive_inframe_deletion ADRA1D 6 81302 7.37989E-5 40651 0 9.5645E-5
20-4202275-C-T p.Glu538Glu synonymous ADRA1D 2 81286 2.46045E-5 40643 0 3.18552E-5
20-4202277-CTG-C p.Ser537fs frameshift ADRA1D 1 81270 1.23047E-5 40635 0 NA
20-4202281-G-T p.Arg536Arg synonymous ADRA1D 1 81134 1.23253E-5 40567 0 4.07027E-6
20-4202286-G-A p.Gln535* stop_gained ADRA1D 3 81070 3.70051E-5 40535 0 2.44429E-5
20-4202288-G-A p.Ala534Val missense ADRA1D 1 80964 1.23512E-5 40482 0 8.73042E-6
20-4202289-C-T p.Ala534Thr missense ADRA1D 2 80980 2.46975E-5 40490 0 NA
20-4202290-G-A p.Cys533Cys synonymous ADRA1D 79 80938 9.76056E-4 40469 0 0.00111865
20-4202291-C-T p.Cys533Tyr missense ADRA1D 2 80974 2.46993E-5 40487 0 1.75076E-5
20-4202293-C-T p.Ala532Ala synonymous ADRA1D 4 80960 4.94071E-5 40480 0 0.00125
20-4202297-G-A p.Ala531Val missense ADRA1D 1 80960 1.23518E-5 40480 0 8.18994E-6
20-4202315-C-G p.Gly525Ala missense ADRA1D 193 80538 0.00239638 40269 0 0.00426888
20-4202315-C-T p.Gly525Asp missense ADRA1D 1 80548 1.2415E-5 40274 0 NA
20-4202319-C-A p.Gly524Trp missense ADRA1D 1 80600 1.24069E-5 40300 0 4.12534E-6
20-4202319-C-T p.Gly524Arg missense ADRA1D 1 80600 1.24069E-5 40300 0 NA
20-4202320-G-A p.Ala523Ala synonymous ADRA1D 3 80542 3.72476E-5 40271 0 1.59327E-4
20-4202333-T-A p.His519Leu missense ADRA1D 12 80292 1.49454E-4 40146 0 2.8677E-4
20-4202335-C-G p.Ser518Ser synonymous ADRA1D 1 80230 1.24642E-5 40115 0 NA
20-4202336-G-T p.Ser518* stop_gained ADRA1D 1 80214 1.24667E-5 40107 0 NA
20-4202348-A-G p.Val514Ala missense ADRA1D 16 79648 2.00884E-4 39824 0 1.75726E-4
20-4202352-T-C p.Lys513Glu missense ADRA1D 5 79502 6.28915E-5 39751 0 2.89805E-5
20-4202355-C-A p.Ala512Ser missense ADRA1D 1 79192 1.26275E-5 39596 0 NA
20-4202360-A-G p.Leu510Pro missense ADRA1D 1 79074 1.26464E-5 39537 0 NA
20-4202366-G-C p.Thr508Ser missense ADRA1D 1 78784 1.26929E-5 39392 0 3.18552E-5
20-4202369-G-A p.Thr507Met missense ADRA1D 1 78532 1.27337E-5 39266 0 1.06365E-5
20-4202378-C-T p.Arg504Gln missense ADRA1D 3 77898 3.85119E-5 38949 0 1.58892E-4
20-4202380-G-C p.Phe503Leu missense ADRA1D 1 77640 1.288E-5 38820 0 NA
20-4202382-A-G p.Phe503Leu missense ADRA1D 1 77396 1.29206E-5 38698 0 1.63486E-4
20-4202382-A-T p.Phe503Ile missense ADRA1D 2 77396 2.58411E-5 38698 0 NA
20-4202385-G-C p.Pro502Ala missense ADRA1D 1 76864 1.301E-5 38432 0 NA
20-4202391-G-A p.Leu500Leu synonymous ADRA1D 2 76400 2.6178E-5 38200 0 6.37227E-5
20-4202393-A-G p.Leu499Pro missense ADRA1D 1 76252 1.31144E-5 38126 0 NA
20-4202403-C-T p.Glu496Lys missense ADRA1D 1 74988 1.33355E-5 37494 0 NA
20-4202427-G-A p.Arg488* stop_gained ADRA1D 1 70314 1.42219E-5 35157 0 1.90556E-5
20-4202436-C-T p.Ala485Thr missense ADRA1D 1 67664 1.47789E-5 33832 0 NA
20-4202439-C-T p.Val484Ile missense ADRA1D 1 67476 1.48201E-5 33738 0 NA
20-4202445-C-G p.Ala482Pro missense ADRA1D 1 66492 1.50394E-5 33246 0 3.19142E-5
20-4202455-G-C p.Pro478Pro synonymous ADRA1D 2 65312 3.06222E-5 32656 0 NA
20-4202459-G-C p.Thr477Arg missense ADRA1D 5 64692 7.72893E-5 32346 0 2.23656E-4
20-4202461-G-C p.Gly476Gly synonymous ADRA1D 11 64636 1.70184E-4 32318 0 1.59765E-4
20-4202470-TTCGGGGTCGGGGTCGGGGAGCGCGGTGAGGGCCAGCGGCGCTCCGGGGGGCGCGTCGCCCGAAC-T p.Ser452fs frameshift ADRA1D 1 65054 1.53718E-5 32527 0 NA
20-4202473-G-T p.Pro472Pro synonymous ADRA1D 1 65218 1.53332E-5 32609 0 1.02775E-4
20-4202481-G-T p.Pro470Thr missense ADRA1D 1 65336 1.53055E-5 32668 0 9.65829E-6
20-4202484-C-T p.Asp469Asn missense ADRA1D 1 64602 1.54794E-5 32301 0 NA
20-4202485-G-C p.Pro468Pro synonymous ADRA1D 1 65386 1.52938E-5 32693 0 NA
20-4202485-G-A p.Pro468Pro synonymous ADRA1D 1 65386 1.52938E-5 32693 0 NA
20-4202489-AGCGCGGTGAGGGCCAGCGGCGCTCCGGGGG-A p.Pro457_Ala466del disruptive_inframe_deletion ADRA1D 2 65392 3.05848E-5 32696 0 NA
20-4202492-G-T p.Ala466Glu missense ADRA1D 1 65502 1.52667E-5 32751 0 NA
20-4202510-G-A p.Ala460Val missense ADRA1D 117 67298 0.00173854 33649 4 0.0017341
20-4202519-G-C p.Pro457Arg missense ADRA1D 3 68824 4.35894E-5 34412 0 1.91473E-4
20-4202520-G-T p.Pro457Thr missense ADRA1D 1 68782 1.45387E-5 34391 0 NA
20-4202520-G-A p.Pro457Ser missense ADRA1D 1 68782 1.45387E-5 34391 0 5.70028E-5
20-4202526-C-T p.Asp455Asn missense ADRA1D 1 69846 1.43172E-5 34923 0 NA
20-4202527-G-A p.Gly454Gly synonymous ADRA1D 1 69982 1.42894E-5 34991 0 3.1904E-5
20-4202537-G-C p.Pro451Arg missense ADRA1D 1 71704 1.39462E-5 35852 0 1.05152E-5
20-4202542-G-A p.Cys449Cys synonymous ADRA1D 1 72224 1.38458E-5 36112 0 9.432E-6
20-4202545-G-A p.Asp448Asp synonymous ADRA1D 1 72798 1.37366E-5 36399 0 1.87406E-4
20-4202552-C-T p.Arg446His missense ADRA1D 1 73248 1.36523E-5 36624 0 1.61173E-5
20-4202558-C-T p.Gly444Asp missense ADRA1D 1 73792 1.35516E-5 36896 0 NA
20-4202564-G-A p.Thr442Ile missense ADRA1D 1 74700 1.33869E-5 37350 0 NA
20-4202573-C-G p.Arg439Pro missense ADRA1D 11 75532 1.45634E-4 37766 0 1.59459E-4
20-4202574-G-A p.Arg439Trp missense ADRA1D 88 75650 0.00116325 37825 0 0.00654308
20-4202580-G-T p.His437Asn missense ADRA1D 4 76338 5.23985E-5 38169 0 3.18796E-5
20-4202593-A-C p.Arg432Arg synonymous ADRA1D 1 77486 1.29056E-5 38743 0 NA
20-4202611-G-GCGCCGGCGACGA p.Arg423_Arg426dup disruptive_inframe_insertion ADRA1D 1 78542 1.2732E-5 39271 0 NA
20-4202615-C-A p.Arg425Leu missense ADRA1D 5 78640 6.35809E-5 39320 0 NA
20-4202615-C-G p.Arg425Pro missense ADRA1D 1 78640 1.27162E-5 39320 0 1.00253E-4
20-4202618-C-T p.Arg424His missense ADRA1D 1 78708 1.27052E-5 39354 0 6.37471E-5
20-4202627-C-T p.Cys421Tyr missense ADRA1D 2 79468 2.51674E-5 39734 0 NA
20-4202630-T-C p.Gln420Arg missense ADRA1D 3 79674 3.76534E-5 39837 0 0.00153061
20-4202634-A-G p.Cys419Arg missense ADRA1D 1 79744 1.25401E-5 39872 0 NA
20-4202637-G-A p.Arg418Cys missense ADRA1D 3 79418 3.77748E-5 39709 0 8.3717E-5
20-4202639-A-C p.Leu417Arg missense ADRA1D 1 79528 1.25742E-5 39764 0 NA
20-4202646-G-A p.Arg415Cys missense ADRA1D 3 79950 3.75235E-5 39975 0 NA
20-4202647-G-A p.Leu414Leu synonymous ADRA1D 1 80026 1.24959E-5 40013 0 NA
20-4202649-G-A p.Leu414Phe missense ADRA1D 15 80158 1.8713E-4 40079 0 3.82263E-4
20-4202655-C-G p.Ala412Pro missense ADRA1D 1 80060 1.24906E-5 40030 0 4.63973E-6
20-4202665-C-T p.Glu408Glu synonymous ADRA1D 39 80702 4.83259E-4 40351 1 9.55901E-4
20-4202667-C-T p.Glu408Lys missense ADRA1D 1 80770 1.23808E-5 40385 0 NA
20-4202670-G-A p.Arg407Cys missense ADRA1D 3 80776 3.71397E-5 40388 0 2.30121E-4
20-4202688-T-C p.Ile401Val missense ADRA1D 1 80474 1.24264E-5 40237 0 5.88014E-5
20-4202695-G-C p.Asn398Lys missense ADRA1D 3 80550 3.72439E-5 40275 0 1.05816E-5
20-4202718-C-T p.Gly391Ser missense ADRA1D 1 80724 1.23879E-5 40362 0 1.21914E-5
20-4202724-A-G p.Trp389Arg missense ADRA1D 2 80884 2.47268E-5 40442 0 1.72807E-5
20-4202740-G-C p.Val383Val synonymous ADRA1D 1 80526 1.24183E-5 40263 0 NA
20-4202741-A-G p.Val383Ala missense ADRA1D 1 80392 1.2439E-5 40196 0 NA
20-4202743-G-A p.Gly382Gly synonymous ADRA1D 2 80424 2.48682E-5 40212 0 4.08333E-6
20-4202750-G-C p.Ser380Trp missense ADRA1D 1 80456 1.24292E-5 40228 0 8.1624E-6
20-4202762-T-A p.Gln376Leu missense ADRA1D 2 80282 2.49122E-5 40141 0 NA
20-4202776-G-A p.Gly371Gly splice_region+synonymous ADRA1D 16 80292 1.99273E-4 40146 0 1.95858E-4
20-4202777-C-A p.Gly371Val missense+splice_region ADRA1D 3 80272 3.73729E-5 40136 0 1.70306E-5
20-4202777-C-G p.Gly371Ala missense+splice_region ADRA1D 1 80272 1.24576E-5 40136 0 8.51528E-6
20-4228491-C-G c.1111+3G>C splice_region ADRA1D 1 79362 1.26005E-5 39681 0 5.71775E-6
20-4228494-C-G p.Gly371Arg missense+splice_region ADRA1D 6 79420 7.55477E-5 39710 0 0.00100806
20-4228512-A-G p.Phe365Leu missense ADRA1D 2 80076 2.49763E-5 40038 0 1.53695E-5
20-4228519-G-T p.Phe362Leu missense ADRA1D 1 80352 1.24452E-5 40176 0 2.38263E-5
20-4228539-C-G p.Val356Leu missense ADRA1D 1 80960 1.23518E-5 40480 0 NA
20-4228542-C-G p.Gly355Arg missense ADRA1D 2 81070 2.467E-5 40535 0 6.37511E-5
20-4228567-C-T p.Ala346Ala synonymous ADRA1D 1 81438 1.22793E-5 40719 0 NA
20-4228568-G-A p.Ala346Val missense ADRA1D 2 81396 2.45712E-5 40698 0 1.49799E-5
20-4228573-C-A p.Lys344Asn missense ADRA1D 4 81422 4.91268E-5 40711 0 4.57094E-5
20-4228579-A-G p.Arg342Arg synonymous ADRA1D 1 81286 1.23022E-5 40643 0 NA
20-4228581-G-C p.Arg342Gly missense ADRA1D 1 81280 1.23031E-5 40640 0 4.36601E-6
20-4228590-T-C p.Lys339Glu missense ADRA1D 1 81094 1.23314E-5 40547 0 3.18674E-5
20-4228593-G-C p.Leu338Val missense ADRA1D 1 80990 1.23472E-5 40495 0 3.18613E-5
20-4228602-C-G p.Val335Leu missense ADRA1D 1 80388 1.24397E-5 40194 0 NA
20-4228603-G-A p.Ser334Ser synonymous ADRA1D 2 80382 2.48812E-5 40191 0 2.04123E-5
20-4228606-G-C p.Leu333Leu synonymous ADRA1D 1 80252 1.24607E-5 40126 0 5.05051E-4
20-4228608-G-A p.Leu333Phe missense ADRA1D 4 80082 4.99488E-5 40041 0 5.05051E-4
20-4228612-G-A p.Ser331Ser synonymous ADRA1D 1 79660 1.25534E-5 39830 0 1.00701E-5
20-4228614-T-C p.Ser331Gly missense ADRA1D 6 79584 7.5392E-5 39792 0 0.00101112
20-4228616-C-T p.Arg330His missense ADRA1D 1 79314 1.26081E-5 39657 0 3.18654E-5
20-4228618-G-A p.Phe329Phe synonymous ADRA1D 1 79314 1.26081E-5 39657 0 0.00101112
20-4228636-G-A p.Ser323Ser synonymous ADRA1D 4 77322 5.17317E-5 38661 0 1.7144E-5
20-4228639-G-A p.Arg322Arg synonymous ADRA1D 18 77126 2.33384E-4 38563 0 1.98046E-4
20-4228641-G-C p.Arg322Gly missense ADRA1D 2 76934 2.59963E-5 38467 0 2.94554E-5
20-4228641-G-A p.Arg322Cys missense ADRA1D 1 76934 1.29982E-5 38467 0 NA
20-4228647-C-G p.Gly320Arg missense ADRA1D 2 76386 2.61828E-5 38193 0 NA
20-4228648-G-A p.His319His synonymous ADRA1D 2 76310 2.62089E-5 38155 0 6.14213E-6
20-4228651-C-A p.Ala318Ala synonymous ADRA1D 1 75910 1.31735E-5 37955 0 NA
20-4228652-G-T p.Ala318Glu missense ADRA1D 1 75800 1.31926E-5 37900 0 6.28765E-6
20-4228652-G-A p.Ala318Val missense ADRA1D 1 75800 1.31926E-5 37900 0 NA
20-4228655-C-T p.Gly317Glu missense ADRA1D 22 76064 2.8923E-4 38032 0 0.00101937
20-4228656-C-G p.Gly317Arg missense ADRA1D 2 76032 2.63047E-5 38016 0 4.67946E-5
20-4228660-G-A p.Ala315Ala synonymous ADRA1D 1 75824 1.31884E-5 37912 0 NA
20-4228662-C-T p.Ala315Thr missense ADRA1D 1 75758 1.31999E-5 37879 0 NA
20-4228666-C-G p.Thr313Thr synonymous ADRA1D 1 75808 1.31912E-5 37904 0 NA
20-4228667-G-C p.Thr313Arg missense ADRA1D 9 75812 1.18715E-4 37906 0 5.11771E-4
20-4228669-G-C p.Ala312Ala synonymous ADRA1D 1 75792 1.3194E-5 37896 0 NA
20-4228674-C-G p.Ala311Pro missense ADRA1D 1 75526 1.32405E-5 37763 0 NA
20-4228675-G-A p.Gly310Gly synonymous ADRA1D 16 75418 2.12151E-4 37709 0 4.17263E-4
20-4228677-C-T p.Gly310Ser missense ADRA1D 10 75538 1.32384E-4 37769 0 3.30369E-5
20-4228679-C-G p.Arg309Pro missense ADRA1D 17 75518 2.25112E-4 37759 0 0.00153689
20-4228680-G-C p.Arg309Gly missense ADRA1D 4 75628 5.28905E-5 37814 0 0.00125
20-4228682-C-G p.Cys308Ser missense ADRA1D 2 75798 2.63859E-5 37899 0 6.42426E-5
20-4228708-G-A p.Ala299Ala synonymous ADRA1D 1 75500 1.3245E-5 37750 0 6.7573E-6
20-4228709-G-A p.Ala299Val missense ADRA1D 2 75474 2.64992E-5 37737 0 3.18979E-5
20-4228716-C-T p.Gly297Ser missense ADRA1D 1 75862 1.31818E-5 37931 0 NA
20-4228719-G-C p.Arg296Gly missense ADRA1D 3 75732 3.96134E-5 37866 0 6.78095E-5
20-4228720-C-T p.Glu295Glu synonymous ADRA1D 4 75880 5.27148E-5 37940 0 6.37714E-5
20-4228721-TC-AA p.Glu295Leu missense ADRA1D 8 75958 1.05321E-4 37979 0 NA
20-4228726-C-G p.Lys293Asn missense ADRA1D 1 76228 1.31185E-5 38114 0 NA
20-4228729-G-C p.Val292Val synonymous ADRA1D 1 76342 1.30989E-5 38171 0 NA
20-4228731-C-T p.Val292Ile missense ADRA1D 1 76384 1.30917E-5 38192 0 6.63394E-6
20-4228732-G-T p.Gly291Gly synonymous ADRA1D 6 76372 7.85628E-5 38186 0 2.04666E-4
20-4228735-C-T p.Ala290Ala synonymous ADRA1D 18588 75922 0.24483 37961 2281 0.331151
20-4228736-G-T p.Ala290Glu missense ADRA1D 1 76564 1.3061E-5 38282 0 NA
20-4228752-T-TGGTGCTGCGCGC p.Thr284_Thr285insAlaArgSerThr conservative_inframe_insertion ADRA1D 1 77412 1.29179E-5 38706 0 5.37346E-5
20-4228757-C-T p.Ser283Asn missense ADRA1D 2 77810 2.57036E-5 38905 0 NA
20-4228761-G-C p.Arg282Gly missense ADRA1D 2 77906 2.5672E-5 38953 0 1.0202E-4
20-4228763-G-A p.Ala281Val missense ADRA1D 53 78012 6.79383E-4 39006 0 8.00881E-4
20-4228766-A-G p.Val280Ala missense ADRA1D 1 78304 1.27707E-5 39152 0 5.88097E-6
20-4228781-C-A p.Cys275Phe missense ADRA1D 1 79158 1.2633E-5 39579 0 8.54628E-5
20-4228784-T-C p.Tyr274Cys missense ADRA1D 1 79370 1.25992E-5 39685 0 1.08165E-5
20-4228801-C-T p.Ala268Ala synonymous ADRA1D 7 79870 8.76424E-5 39935 0 1.82628E-4
20-4228801-C-A p.Ala268Ala synonymous ADRA1D 2 79870 2.50407E-5 39935 0 3.18573E-5
20-4228804-C-T p.Met267Ile missense ADRA1D 1 80062 1.24903E-5 40031 0 NA
20-4228822-G-A p.Cys261Cys synonymous ADRA1D 1 80478 1.24258E-5 40239 0 3.15416E-4
20-4228827-CGGA-C p.Ser259del conservative_inframe_deletion ADRA1D 3 80508 3.72634E-5 40254 0 4.96312E-6
20-4228827-C-T p.Val260Met missense ADRA1D 6 80508 7.45268E-5 40254 0 1.98525E-5
20-4228828-G-A p.Ser259Ser synonymous ADRA1D 1 80592 1.24082E-5 40296 0 8.93389E-5
20-4228850-G-A p.Ala252Val missense ADRA1D 3 80728 3.71618E-5 40364 0 5.02311E-5
20-4228857-C-T p.Glu250Lys missense ADRA1D 3 80772 3.71416E-5 40386 0 NA
20-4228866-C-T p.Gly247Ser missense ADRA1D 4 80802 4.95037E-5 40401 0 6.25E-4
20-4228867-G-A p.Cys246Cys synonymous ADRA1D 115 80796 0.00142334 40398 1 0.00277123
20-4228869-A-T p.Cys246Ser missense ADRA1D 1 80820 1.23732E-5 40410 0 NA
20-4228873-G-A p.Arg244Arg synonymous ADRA1D 3 80808 3.7125E-5 40404 0 NA
20-4228882-A-AG p.Asp242fs frameshift ADRA1D 1 80824 1.23726E-5 40412 0 4.38397E-6
20-4228883-G-A p.Pro241Leu missense ADRA1D 14 80816 1.73233E-4 40408 0 2.29577E-4
20-4228883-G-C p.Pro241Arg missense ADRA1D 4 80816 4.94951E-5 40408 0 8.82987E-5
20-4228884-G-T p.Pro241Thr missense ADRA1D 2 80800 2.47525E-5 40400 0 3.18512E-5
20-4228885-G-C p.Pro240Pro synonymous ADRA1D 1 80796 1.23769E-5 40398 0 4.36304E-6
20-4228886-G-A p.Pro240Leu missense ADRA1D 3 80780 3.71379E-5 40390 0 3.18451E-5
20-4228895-T-G p.Glu237Ala missense ADRA1D 2 80806 2.47506E-5 40403 0 NA
20-4228896-C-G p.Glu237Gln missense ADRA1D 1 80814 1.23741E-5 40407 0 NA
20-4228903-G-A p.Gly234Gly synonymous ADRA1D 1 80850 1.23686E-5 40425 0 NA
20-4228908-G-A p.Leu233Leu synonymous ADRA1D 1 80836 1.23707E-5 40418 0 6.36983E-5
20-4228908-G-C p.Leu233Val missense ADRA1D 1 80836 1.23707E-5 40418 0 NA
20-4228911-G-A p.Leu232Leu synonymous ADRA1D 2 80900 2.47219E-5 40450 0 3.18431E-5
20-4228920-C-T p.Val229Ile missense ADRA1D 1 80898 1.23612E-5 40449 0 NA
20-4228921-G-C p.Ser228Ser synonymous ADRA1D 25 80884 3.09085E-4 40442 0 3.84869E-4
20-4228929-C-T p.Val226Met missense ADRA1D 1 80936 1.23554E-5 40468 0 NA
20-4228930-C-T p.Leu225Leu synonymous ADRA1D 1 80982 1.23484E-5 40491 0 6.37227E-5
20-4228938-C-A p.Val223Leu missense ADRA1D 1 80988 1.23475E-5 40494 0 NA
20-4228941-C-T p.Val222Ile missense ADRA1D 2 81018 2.46859E-5 40509 0 1.33747E-5
20-4228943-C-G p.Trp221Ser missense ADRA1D 1 81028 1.23414E-5 40514 0 NA
20-4228952-G-A p.Ala218Val missense ADRA1D 2 81056 2.46743E-5 40528 0 1.3317E-5
20-4228977-C-G p.Glu210Gln missense ADRA1D 3 81274 3.69122E-5 40637 0 1.32799E-5
20-4228978-G-A p.Thr209Thr synonymous ADRA1D 1 81288 1.23019E-5 40644 0 NA
20-4228998-T-C p.Lys203Glu missense ADRA1D 2 81470 2.45489E-5 40735 0 1.28225E-5
20-4229003-G-A p.Ser201Leu missense ADRA1D 18 81494 2.20875E-4 40747 0 2.23044E-4
20-4229022-A-G p.Tyr195His missense ADRA1D 1 81686 1.2242E-5 40843 0 3.18735E-5
20-4229022-A-T p.Tyr195Asn missense ADRA1D 2 81686 2.4484E-5 40843 0 NA
20-4229023-C-G p.Arg194Arg synonymous ADRA1D 3 81692 3.67233E-5 40846 0 1.21318E-5
20-4229026-G-C p.Asp193Glu missense ADRA1D 2 81734 2.44696E-5 40867 0 3.5985E-5
20-4229049-T-C p.Ser186Gly missense ADRA1D 2 81890 2.4423E-5 40945 0 1.66607E-5
20-4229052-G-A p.Leu185Phe missense ADRA1D 1 81908 1.22088E-5 40954 0 1.37429E-4
20-4229056-G-A p.Ser183Ser synonymous ADRA1D 1 81836 1.22196E-5 40918 0 NA
20-4229061-C-T p.Ala182Thr missense ADRA1D 2 81658 2.44924E-5 40829 0 1.68053E-5
20-4229063-G-T p.Thr181Lys missense ADRA1D 1 81740 1.22339E-5 40870 0 4.18484E-6
20-4229074-CA-C p.Val177fs frameshift ADRA1D 1 81856 1.22166E-5 40928 0 NA
20-4229076-C-A p.Val177Leu missense ADRA1D 1 81852 1.22172E-5 40926 0 NA
20-4229078-T-C p.Asp176Gly missense ADRA1D 1 81892 1.22112E-5 40946 0 1.23743E-5
20-4229082-C-T p.Val175Met missense ADRA1D 2 81892 2.44224E-5 40946 0 NA
20-4229083-G-A p.Ala174Ala synonymous ADRA1D 2 81900 2.442E-5 40950 0 NA
20-4229086-G-T p.Ala173Ala synonymous ADRA1D 2 81908 2.44176E-5 40954 0 1.04817E-5
20-4229088-C-T p.Ala173Thr missense ADRA1D 1 81910 1.22085E-5 40955 0 4.10998E-6
20-4229103-A-G p.Phe168Leu missense ADRA1D 2 82008 2.43879E-5 41004 0 2.00509E-5
20-4229111-C-T p.Gly165Asp missense ADRA1D 1 81964 1.22005E-5 40982 0 4.06669E-6
20-4229112-C-G p.Gly165Arg missense ADRA1D 2 81990 2.43932E-5 40995 0 3.18674E-5
20-4229121-A-C p.Trp162Gly missense ADRA1D 1 81988 1.21969E-5 40994 0 4.04485E-6
20-4229146-C-T p.Ser153Ser synonymous ADRA1D 1 81620 1.22519E-5 40810 0 3.18918E-5
20-4229149-G-A p.Phe152Phe synonymous ADRA1D 1 81666 1.2245E-5 40833 0 4.01603E-6
20-4229155-C-G p.Leu150Leu synonymous ADRA1D 1 81484 1.22723E-5 40742 0 NA
20-4229167-G-A p.Ser146Ser synonymous ADRA1D 2 81020 2.46853E-5 40510 0 2.62169E-5
20-4229206-ATAGT-A p.Asn132fs frameshift ADRA1D 1 79516 1.25761E-5 39758 0 NA
20-4229218-G-A p.Thr129Thr synonymous ADRA1D 803 78456 0.010235 39228 48 0.0427748
20-4229221-C-T p.Gln128Gln synonymous ADRA1D 2 78298 2.55434E-5 39149 0 4.02551E-6
20-4229224-C-T p.Leu127Leu synonymous ADRA1D 33 78154 4.22243E-4 39077 0 4.27051E-4
20-4229235-T-G p.Asn124His missense ADRA1D 10 77318 1.29336E-4 38659 0 1.59806E-4
20-4229237-C-T p.Cys123Tyr missense ADRA1D 1 76996 1.29877E-5 38498 0 NA
20-4229272-C-T p.Val111Val synonymous ADRA1D 5 74180 6.74036E-5 37090 0 4.73153E-5
20-4229274-C-T p.Val111Met missense ADRA1D 3 73880 4.06064E-5 36940 0 0.00100908
20-4229283-G-A p.Leu108Phe missense ADRA1D 2 73158 2.73381E-5 36579 0 3.20143E-5
20-4229295-C-A p.Ala104Ser missense ADRA1D 1 70512 1.4182E-5 35256 0 NA
20-4229324-G-A p.Ala94Val missense ADRA1D 1 61274 1.63201E-5 30637 0 0.00151976
20-4229332-C-T p.Val91Val synonymous ADRA1D 23 59850 3.84294E-4 29925 0 0.0015213
20-4229339-C-T p.Gly89Glu missense ADRA1D 1 58338 1.71415E-5 29169 0 NA
20-4229340-C-G p.Gly89Arg missense ADRA1D 1 58114 1.72076E-5 29057 0 NA
20-4229360-T-G p.Asn82Thr missense ADRA1D 1 51408 1.94522E-5 25704 0 6.20686E-6
20-4229365-G-C p.Asp80Glu missense ADRA1D 3 49608 6.04741E-5 24804 0 9.9397E-5
20-4229369-C-CCGCCCG p.Ala77_Gly78dup conservative_inframe_insertion ADRA1D 1 47902 2.0876E-5 23951 0 NA
20-4229375-G-T p.Ala77Glu missense ADRA1D 398 45662 0.00871622 22831 2 0.013048
20-4229375-G-A p.Ala77Val missense ADRA1D 1 45688 2.18876E-5 22844 0 NA
20-4229379-C-CCGCGCT p.Ala75_Gly76insSerAla conservative_inframe_insertion ADRA1D 4 44976 8.89363E-5 22488 0 3.41647E-5
20-4229379-C-G p.Gly76Arg missense ADRA1D 1 44978 2.22331E-5 22489 0 3.41647E-5
20-4229383-G-A p.Ser74Ser synonymous ADRA1D 4 43744 9.14411E-5 21872 0 5.29661E-4
20-4229386-C-T p.Gly73Gly synonymous ADRA1D 1 43506 2.29853E-5 21753 0 7.84929E-6
20-4229396-C-T p.Gly70Glu missense ADRA1D 1 41892 2.38709E-5 20946 0 NA
20-4229404-G-T p.Ser67Arg missense ADRA1D 1 40558 2.4656E-5 20279 0 0.0120048
20-4229413-G-C p.Asp64Glu missense ADRA1D 1 39626 2.5236E-5 19813 0 1.75765E-4
20-4229423-C-T p.Ser61Asn missense ADRA1D 2 36104 5.53955E-5 18052 0 NA
20-4229437-C-A p.Val56Val synonymous ADRA1D 12 30520 3.93185E-4 15260 0 9.5549E-4
20-4229438-ACGCCGC-A p.Gly54_Gly55del disruptive_inframe_deletion ADRA1D 9 30332 2.96716E-4 15166 0 0.00173611
20-4229448-C-T p.Gly53Ser missense ADRA1D 6 29010 2.06825E-4 14505 0 1.62167E-4
20-4229452-G-A p.Gly51Gly synonymous ADRA1D 4 28508 1.40311E-4 14254 0 5.28369E-4
20-4229458-G-GC p.Ala50fs frameshift ADRA1D 1 27756 3.60282E-5 13878 0 4.08397E-5
20-4229458-G-A p.Gly49Gly synonymous ADRA1D 2 27758 7.20513E-5 13879 0 NA
20-4229459-C-T p.Gly49Asp missense ADRA1D 1 27758 3.60256E-5 13879 0 8.15528E-5
20-4229464-C-T p.Pro47Pro synonymous ADRA1D 20 27314 7.32225E-4 13657 0 0.0128205
20-4229467-C-T p.Val46Val synonymous ADRA1D 1 26610 3.75799E-5 13305 0 NA
20-4229472-C-A p.Gly45Cys missense ADRA1D 1 26046 3.83936E-5 13023 0 NA
20-4229479-C-G p.Ala42Ala synonymous ADRA1D 3 25004 1.19981E-4 12502 0 2.03318E-4
20-4229496-G-T p.Pro37Thr missense ADRA1D 7 23628 2.96259E-4 11814 0 7.36799E-4
20-4229497-GGCCGC-G p.Ala35fs frameshift ADRA1D 3 23406 1.28172E-4 11703 0 NA
20-4229500-C-T p.Ala35Ala synonymous ADRA1D 1 22768 4.39213E-5 11384 0 NA
20-4229501-G-C p.Ala35Gly missense ADRA1D 8 22172 3.60815E-4 11086 0 0.00390625
20-4229501-G-GCGCCGCCCGCGCTGCCCC p.Gly29_Gly34dup conservative_inframe_insertion ADRA1D 1 22174 4.50979E-5 11087 0 NA
20-4229505-CGCCCGCGCT-C p.Ser31_Gly33del conservative_inframe_deletion ADRA1D 1 22356 4.47307E-5 11178 0 0.266667
20-4229514-T-C p.Ser31Gly missense ADRA1D 4738 22762 0.208154 11381 373 0.3125
20-4229517-C-T p.Gly30Ser missense ADRA1D 1 24756 4.03942E-5 12378 0 NA
20-4229520-C-A p.Gly29Trp missense ADRA1D 1 25262 3.95851E-5 12631 0 3.87717E-5
20-4229539-G-C p.Gly22Gly synonymous ADRA1D 1 29626 3.37541E-5 14813 0 NA
20-4229546-GC-CT p.Ala20Arg missense ADRA1D 1 33602 2.97601E-5 16801 0 NA
20-4229546-G-C p.Ala20Gly missense ADRA1D 2 33602 5.95203E-5 16801 0 0.00202703
20-4229547-C-T p.Ala20Thr missense ADRA1D 2 33686 5.93718E-5 16843 0 0.00404858
20-4229554-G-C p.Asp17Glu missense ADRA1D 1 35218 2.83946E-5 17609 0 NA
20-4229558-G-C p.Pro16Arg missense ADRA1D 82 35598 0.0023035 17799 1 0.00412732
20-4229567-C-T p.Gly13Glu missense ADRA1D 1 36310 2.75406E-5 18155 0 NA
20-4229580-C-T p.Val9Ile missense ADRA1D 2 36804 5.43419E-5 18402 0 3.37861E-5
20-4229584-C-G p.Leu7Leu synonymous ADRA1D 2 36948 5.41301E-5 18474 0 1.33433E-5
20-4229585-A-T p.Leu7Gln missense ADRA1D 9 36830 2.44366E-4 18415 0 0.00453001
20-4229596-GAA-G p.Phe3fs frameshift ADRA1D 1 36994 2.70314E-5 18497 0 NA
20-4229684-G-A c.-80C>T 5_prime_UTR_premature_start_codon_gain ADRA1D 1 32414 3.08509E-5 16207 0 6.34518E-4