Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
5-159343857-C-T c.-56C>T 5_prime_UTR_premature_start_codon_gain ADRA1B 2 81008 2.46889E-5 40504 0 NA
5-159343860-C-T c.-53C>T 5_prime_UTR_premature_start_codon_gain ADRA1B 3 81086 3.69978E-5 40543 0 6.38081E-5
5-159343927-G-A p.Leu5Leu synonymous ADRA1B 1 82674 1.20957E-5 41337 0 NA
5-159343929-A-G p.Asp6Gly missense ADRA1B 1 82668 1.20966E-5 41334 0 NA
5-159343934-G-A p.Gly8Ser missense ADRA1B 1 82794 1.20782E-5 41397 0 8.49675E-6
5-159343937-C-T p.His9Tyr missense ADRA1B 5 82912 6.03049E-5 41456 0 1.27445E-4
5-159343944-C-T p.Thr11Ile missense ADRA1B 1 82990 1.20496E-5 41495 0 3.18512E-5
5-159343952-C-T p.Pro14Ser missense ADRA1B 1 83048 1.20412E-5 41524 0 3.18634E-5
5-159343969-G-A p.Glu19Glu synonymous ADRA1B 2 83150 2.40529E-5 41575 0 8.26241E-6
5-159343983-A-C p.Asn24Thr missense ADRA1B 13 83170 1.56306E-4 41585 0 1.27747E-4
5-159343990-T-C p.Thr26Thr synonymous ADRA1B 7 83146 8.41893E-5 41573 0 0.00132738
5-159343998-A-G p.Asn29Ser missense ADRA1B 1 83162 1.20247E-5 41581 0 1.9888E-5
5-159344008-G-A p.Ser32Ser synonymous ADRA1B 1 83138 1.20282E-5 41569 0 3.97763E-6
5-159344026-C-A p.Pro38Pro synonymous ADRA1B 1 83108 1.20325E-5 41554 0 8.2409E-6
5-159344038-C-T p.Ile42Ile synonymous ADRA1B 5 83098 6.01699E-5 41549 0 1.91278E-4
5-159344040-C-T p.Thr43Ile missense ADRA1B 132 83090 0.00158864 41545 2 7.23796E-4
5-159344048-A-G p.Ile46Val missense ADRA1B 2 83084 2.4072E-5 41542 0 3.18857E-5
5-159344049-T-C p.Ile46Thr missense ADRA1B 6 83076 7.2223E-5 41538 0 3.97693E-5
5-159344050-C-T p.Ile46Ile synonymous ADRA1B 1 83072 1.20378E-5 41536 0 NA
5-159344083-C-T p.Leu57Leu synonymous ADRA1B 2116 83050 0.0254786 41525 31 0.0327979
5-159344090-A-G p.Ile60Val missense ADRA1B 1 83074 1.20375E-5 41537 0 NA
5-159344122-G-A p.Val70Val synonymous ADRA1B 5 83020 6.02265E-5 41510 0 6.25E-4
5-159344128-C-T p.Cys72Cys synonymous ADRA1B 1 82990 1.20496E-5 41495 0 8.24198E-6
5-159344129-A-G p.Asn73Asp missense ADRA1B 2 83008 2.40941E-5 41504 0 NA
5-159344133-G-C p.Arg74Pro missense ADRA1B 2 82988 2.40999E-5 41494 0 3.29663E-5
5-159344141-C-T p.Arg77Trp missense ADRA1B 2 82938 2.41144E-5 41469 0 6.37592E-5
5-159344145-C-T p.Thr78Met missense ADRA1B 4 82896 4.82532E-5 41448 0 1.19378E-5
5-159344148-C-T p.Pro79Leu missense ADRA1B 3 82880 3.61969E-5 41440 0 3.97858E-6
5-159344149-C-T p.Pro79Pro synonymous ADRA1B 1 82892 1.20639E-5 41446 0 1.64813E-5
5-159344151-C-T p.Thr80Ile missense ADRA1B 1 82884 1.20651E-5 41442 0 1.19359E-5
5-159344157-ACTT-A p.Phe83del conservative_inframe_deletion ADRA1B 1 82882 1.20653E-5 41441 0 NA
5-159344188-G-A p.Leu92Leu synonymous ADRA1B 1 82882 1.20653E-5 41441 0 8.239E-6
5-159344213-T-C p.Phe101Leu missense ADRA1B 1 82884 1.20651E-5 41442 0 NA
5-159344215-C-G p.Phe101Leu missense ADRA1B 2 82876 2.41324E-5 41438 0 8.239E-6
5-159344221-G-A p.Ala103Ala synonymous ADRA1B 2 82746 2.41704E-5 41373 0 1.19338E-5
5-159344223-C-T p.Ala104Val missense ADRA1B 2 82732 2.41744E-5 41366 0 NA
5-159344236-C-T p.Leu108Leu synonymous ADRA1B 9 82690 1.0884E-4 41345 0 6.37389E-5
5-159344237-G-A p.Gly109Ser missense ADRA1B 1 82666 1.20969E-5 41333 0 1.64802E-5
5-159344240-T-C p.Tyr110His missense ADRA1B 1 82694 1.20928E-5 41347 0 NA
5-159344241-A-C p.Tyr110Ser missense ADRA1B 1 82686 1.20939E-5 41343 0 NA
5-159344255-C-A p.Arg115Arg synonymous ADRA1B 1 82622 1.21033E-5 41311 0 1.3926E-4
5-159344256-G-A p.Arg115Gln missense ADRA1B 1 82658 1.2098E-5 41329 0 NA
5-159344305-G-A p.Ala131Ala synonymous ADRA1B 1 82950 1.20555E-5 41475 0 3.29625E-5
5-159344318-CTG-C p.Cys137fs frameshift ADRA1B 1 83030 1.20438E-5 41515 0 NA
5-159344323-C-T p.Cys137Cys synonymous ADRA1B 6 83022 7.227E-5 41511 0 1.59357E-4
5-159344323-C-G p.Cys137Trp missense ADRA1B 1 83022 1.2045E-5 41511 0 NA
5-159344334-T-C p.Ile141Thr missense ADRA1B 1 83096 1.20343E-5 41548 0 3.18735E-5
5-159344344-C-T p.Tyr144Tyr synonymous ADRA1B 1 83102 1.20334E-5 41551 0 NA
5-159344347-C-A p.Ile145Ile synonymous ADRA1B 6 83110 7.21935E-5 41555 0 6.37389E-5
5-159344350-G-T p.Gly146Gly synonymous ADRA1B 4 83100 4.81348E-5 41550 0 NA
5-159344351-G-A p.Val147Met missense ADRA1B 1 83108 1.20325E-5 41554 0 3.98245E-6
5-159344352-T-C p.Val147Ala missense ADRA1B 4 83108 4.81301E-5 41554 0 1.64813E-5
5-159344359-C-T p.Tyr149Tyr synonymous ADRA1B 1 83138 1.20282E-5 41569 0 NA
5-159344365-G-A p.Leu151Leu synonymous ADRA1B 7 83110 8.42257E-5 41555 0 1.07121E-4
5-159344377-G-T p.Thr155Thr synonymous ADRA1B 2 83114 2.40633E-5 41557 0 3.97918E-6
5-159344387-C-T p.Arg159Trp missense ADRA1B 1 83118 1.20311E-5 41559 0 8.24158E-6
5-159344389-G-C p.Arg159Arg synonymous ADRA1B 1 83122 1.20305E-5 41561 0 NA
5-159344395-G-A p.Lys161Lys synonymous ADRA1B 1 83168 1.20239E-5 41584 0 NA
5-159344402-T-C p.Leu164Leu synonymous ADRA1B 2 83172 2.40466E-5 41586 0 3.97823E-6
5-159344413-C-T p.Leu167Leu synonymous ADRA1B 3 83152 3.60785E-5 41576 0 3.97741E-6
5-159344414-A-G p.Ser168Gly missense ADRA1B 1 83160 1.2025E-5 41580 0 1.64772E-5
5-159344416-T-C p.Ser168Ser synonymous ADRA1B 1 83152 1.20262E-5 41576 0 NA
5-159344430-C-T p.Ser173Phe missense ADRA1B 1 83168 1.20239E-5 41584 0 NA
5-159344435-G-A p.Val175Ile missense ADRA1B 2 83198 2.4039E-5 41599 0 2.47154E-5
5-159344438-A-G p.Ile176Val missense ADRA1B 1 83228 1.20152E-5 41614 0 1.19313E-5
5-159344446-C-T p.Ile178Ile synonymous ADRA1B 2130 83190 0.025604 41595 31 0.0327874
5-159344447-G-A p.Gly179Arg missense ADRA1B 1 83204 1.20187E-5 41602 0 3.97744E-6
5-159344449-G-T p.Gly179Gly synonymous ADRA1B 2 83212 2.4035E-5 41606 0 NA
5-159344461-G-A p.Gly183Gly synonymous ADRA1B 14934 82984 0.179962 41492 1406 0.20997
5-159344469-A-G p.Glu186Gly missense ADRA1B 3 83264 3.603E-5 41632 0 1.64764E-5
5-159344472-C-T p.Pro187Leu missense ADRA1B 1 83268 1.20094E-5 41634 0 3.18654E-5
5-159344493-A-T p.Glu194Val missense ADRA1B 1 83328 1.20008E-5 41664 0 8.23968E-6
5-159344497-C-T p.Cys195Cys synonymous ADRA1B 1 83330 1.20005E-5 41665 0 7.96147E-6
5-159344499-G-A p.Gly196Glu missense ADRA1B 2 83338 2.39987E-5 41669 0 7.95887E-6
5-159344515-C-T p.Pro201Pro synonymous ADRA1B 4 83368 4.798E-5 41684 0 3.18634E-5
5-159344545-C-T p.Ser211Ser synonymous ADRA1B 1 83396 1.1991E-5 41698 0 3.97931E-6
5-159344550-A-T p.Tyr213Phe missense ADRA1B 1 83392 1.19916E-5 41696 0 NA
5-159344551-C-T p.Tyr213Tyr synonymous ADRA1B 1 83392 1.19916E-5 41696 0 NA
5-159344562-C-T p.Ala217Val missense ADRA1B 10 83386 1.19924E-4 41693 0 0.00375
5-159344563-G-A p.Ala217Ala synonymous ADRA1B 1 83390 1.19918E-5 41695 0 0.00151057
5-159344568-T-C p.Ile219Thr missense ADRA1B 1 83390 1.19918E-5 41695 0 NA
5-159344575-C-T p.Val221Val synonymous ADRA1B 1 83388 1.19921E-5 41694 0 3.97791E-6
5-159344585-C-G p.Arg225Gly missense ADRA1B 1 83384 1.19927E-5 41692 0 3.1902E-5
5-159344586-G-A p.Arg225His missense ADRA1B 1 83386 1.19924E-5 41693 0 1.64747E-5
5-159344592-A-G p.Tyr227Cys missense ADRA1B 2 83382 2.3986E-5 41691 0 NA
5-159344599-G-A p.Val229Val synonymous ADRA1B 19 83384 2.27861E-4 41692 0 2.23172E-4
5-159344610-C-T p.Thr233Ile missense ADRA1B 5 83382 5.9965E-5 41691 0 NA
5-159344617-G-C p.Lys235Asn missense ADRA1B 1 83380 1.19933E-5 41690 0 NA
5-159344620-C-T p.Asn236Asn synonymous ADRA1B 2 83378 2.39871E-5 41689 0 NA
5-159344623-A-G p.Leu237Leu synonymous ADRA1B 19 83378 2.27878E-4 41689 0 9.56755E-4
5-159344641-G-A p.Lys243Lys synonymous ADRA1B 1 83352 1.19973E-5 41676 0 NA
5-159344648-T-C p.Ser246Pro missense ADRA1B 1 83352 1.19973E-5 41676 0 1.19305E-5
5-159344652-A-G p.Asn247Ser missense ADRA1B 2 83356 2.39935E-5 41678 0 3.97674E-6
5-159344657-A-G p.Lys249Glu missense ADRA1B 3 83352 3.59919E-5 41676 0 NA
5-159344663-C-A p.Leu251Met missense ADRA1B 1 83348 1.19979E-5 41674 0 NA
5-159344682-C-T p.Ser257Phe missense ADRA1B 2 83296 2.40108E-5 41648 0 NA
5-159344686-G-A p.Lys258Lys synonymous ADRA1B 2 83294 2.40113E-5 41647 0 NA
5-159344695-C-T p.His261His synonymous ADRA1B 4 83262 4.80411E-5 41631 0 6.37146E-5
5-159344703-C-A p.Thr264Asn missense ADRA1B 2 83234 2.40286E-5 41617 0 3.97772E-6
5-159344705-C-A p.Leu265Ile missense ADRA1B 1 83224 1.20158E-5 41612 0 5.03525E-4
5-159344712-GTAC-G p.Thr268del disruptive_inframe_deletion ADRA1B 9 83188 1.08189E-4 41594 0 4.13189E-5
5-159344714-A-G p.Thr268Ala missense ADRA1B 1 83188 1.2021E-5 41594 0 1.1934E-5
5-159344719-G-C p.Lys269Asn missense ADRA1B 1 83156 1.20256E-5 41578 0 1.59127E-5
5-159344721-C-G p.Ala270Gly missense ADRA1B 1 83148 1.20267E-5 41574 0 NA
5-159344725-G-A p.Lys271Lys synonymous ADRA1B 1 83152 1.20262E-5 41576 0 8.27185E-6
5-159344736-C-T p.Pro275Leu missense ADRA1B 2 83098 2.4068E-5 41549 0 NA
5-159344748-T-C p.Ile279Thr missense ADRA1B 3 83036 3.61289E-5 41518 0 1.664E-5
5-159344753-G-A p.Val281Ile missense ADRA1B 3 82952 3.61655E-5 41476 0 0.00125
5-159344764-T-C p.Phe284Phe synonymous ADRA1B 1 82778 1.20805E-5 41389 0 NA
5-159344779-A-G p.Glu289Glu synonymous ADRA1B 2 82330 2.42925E-5 41165 0 8.41312E-6
5-159344794-G-A p.Lys294Lys synonymous ADRA1B 1 81790 1.22264E-5 40895 0 NA
5-159344796-C-T p.Thr295Met missense ADRA1B 1 81696 1.22405E-5 40848 0 4.25091E-5
5-159344797-G-T p.Thr295Thr synonymous ADRA1B 5 81630 6.1252E-5 40815 0 5.03525E-4
5-159344812-C-T p.Val300Val synonymous ADRA1B 16 81368 1.96637E-4 40684 0 2.59412E-5
5-159344812-C-G p.Val300Val synonymous ADRA1B 3 81368 3.68695E-5 40684 0 3.18471E-5
5-159344813-G-A p.Gly301Ser missense ADRA1B 4 81334 4.91799E-5 40667 0 4.32893E-5
5-159344830-C-T p.Cys306Cys synonymous ADRA1B 2 81140 2.46488E-5 40570 0 NA
5-159344856-C-A p.Pro315Gln missense ADRA1B 2 80528 2.48361E-5 40264 0 NA
5-159344857-G-A p.Pro315Pro synonymous ADRA1B 20 80450 2.48602E-4 40225 0 2.74735E-5
5-159344866-GT-G c.949+6delT splice_region ADRA1B 17 80156 2.12086E-4 40078 0 1.91046E-4
5-159344867-T-C c.949+6T>C splice_region ADRA1B 2 80110 2.49657E-5 40055 0 9.23174E-6
5-159398882-G-A c.950-4G>A splice_region ADRA1B 2 72162 2.77154E-5 36081 0 9.40256E-6
5-159398903-C-A p.Leu323Met missense ADRA1B 2 73310 2.72814E-5 36655 0 NA
5-159398912-C-T p.Pro326Ser missense ADRA1B 2 73702 2.71363E-5 36851 0 NA
5-159398923-G-A p.Val329Val synonymous ADRA1B 11 74054 1.4854E-4 37027 0 2.45987E-5
5-159398930-G-C p.Val332Leu missense ADRA1B 12 74554 1.60957E-4 37277 0 0.00125
5-159398949-A-G p.Tyr338Cys missense ADRA1B 3 76168 3.93866E-5 38084 0 5.46831E-6
5-159398971-C-T p.Pro345Pro synonymous ADRA1B 1 77648 1.28786E-5 38824 0 NA
5-159398972-A-G p.Ile346Val missense ADRA1B 1 77640 1.288E-5 38820 0 NA
5-159398993-AAGG-A p.Glu354del conservative_inframe_deletion ADRA1B 1 77418 1.29169E-5 38709 0 1.01684E-5
5-159399005-C-T p.Arg357Cys missense ADRA1B 6 76756 7.81698E-5 38378 1 6.50957E-5
5-159399005-C-A p.Arg357Ser missense ADRA1B 4 76756 5.21132E-5 38378 0 5.17206E-5
5-159399018-G-A p.Arg361His missense ADRA1B 2 75108 2.66283E-5 37554 0 3.30055E-5
5-159399018-G-C p.Arg361Pro missense ADRA1B 1 75108 1.33142E-5 37554 0 NA
5-159399018-G-T p.Arg361Leu missense ADRA1B 2 75108 2.66283E-5 37554 0 5.03525E-4
5-159399029-T-C p.Cys365Arg missense ADRA1B 1 73284 1.36455E-5 36642 0 NA
5-159399034-G-T p.Gln366His missense ADRA1B 2 72102 2.77385E-5 36051 0 8.61673E-5
5-159399035-T-TGCCGCG p.Gly371_Arg372dup conservative_inframe_insertion ADRA1B 4 71704 5.57849E-5 35852 0 5.95238E-5
5-159399037-C-T p.Cys367Cys synonymous ADRA1B 87 71418 0.00121818 35709 0 0.00291862
5-159399038-C-G p.Arg368Gly missense ADRA1B 1 70782 1.41279E-5 35391 0 1.34084E-5
5-159399041-GGCCGCGGCCGCCGCCGAC-G p.Gly371_Arg376del conservative_inframe_deletion ADRA1B 7 70086 9.98773E-5 35043 0 4.12855E-5
5-159399042-G-A p.Gly369Asp missense ADRA1B 1 69710 1.43451E-5 34855 0 NA
5-159399043-C-T p.Gly369Gly synonymous ADRA1B 3 69660 4.30663E-5 34830 0 3.00643E-5
5-159399044-C-G p.Arg370Gly missense ADRA1B 1 69050 1.44823E-5 34525 0 9.1617E-6
5-159399044-C-T p.Arg370Cys missense ADRA1B 1 69052 1.44818E-5 34526 0 NA
5-159399047-GGCCGCCGCCGAC-G p.Arg375_Arg378del disruptive_inframe_deletion ADRA1B 1 68866 1.4521E-5 34433 0 NA
5-159399049-C-CCGCCGCCGA p.Arg375_Arg377dup disruptive_inframe_insertion ADRA1B 194 68922 0.00281478 34461 0 0.00265776
5-159399049-C-CACTGGCA p.Arg372fs frameshift ADRA1B 1 68930 1.45075E-5 34465 0 NA
5-159399049-CCGCCGCCGA-C p.Arg375_Arg377del disruptive_inframe_deletion ADRA1B 2 68930 2.90149E-5 34465 0 3.13686E-5
5-159399052-C-A p.Arg372Arg synonymous ADRA1B 53 68718 7.71268E-4 34359 1 0.00611621
5-159399052-C-CCGCCGA p.Arg375_Arg376dup disruptive_inframe_insertion ADRA1B 19 68720 2.76484E-4 34360 0 2.04638E-4
5-159399055-CCGACGCCGCCGCCGCCGT-C p.Arg375_Arg380del disruptive_inframe_deletion ADRA1B 1 68596 1.45781E-5 34298 0 NA
5-159399057-G-A p.Arg374Gln missense ADRA1B 59 68340 8.6333E-4 34170 0 0.00444162
5-159399058-A-ACGC p.Arg379dup disruptive_inframe_insertion ADRA1B 7 68218 1.02612E-4 34109 0 3.49479E-5
5-159399058-A-C p.Arg374Arg synonymous ADRA1B 1 68218 1.46589E-5 34109 0 0.00204918
5-159399058-A-ACGCCGC p.Arg378_Arg379dup disruptive_inframe_insertion ADRA1B 1 68218 1.46589E-5 34109 0 NA
5-159399060-G-A p.Arg375His missense ADRA1B 1 67984 1.47093E-5 33992 0 NA
5-159399067-C-A p.Arg377Arg synonymous ADRA1B 6 67408 8.90102E-5 33704 0 0.00172883
5-159399067-C-CCGCCGT p.Arg379_Arg380dup disruptive_inframe_insertion ADRA1B 1 67408 1.4835E-5 33704 0 6.80643E-5
5-159399071-C-G p.Arg379Gly missense ADRA1B 1 67110 1.49009E-5 33555 0 3.06241E-5
5-159399073-T-C p.Arg379Arg synonymous ADRA1B 1 67010 1.49231E-5 33505 0 5.5517E-4
5-159399082-C-A p.Gly382Gly synonymous ADRA1B 2 66518 3.0067E-5 33259 0 NA
5-159399089-G-A p.Ala385Thr missense ADRA1B 1 66886 1.49508E-5 33443 0 3.64964E-5
5-159399090-C-A p.Ala385Asp missense ADRA1B 1 66912 1.4945E-5 33456 0 NA
5-159399099-A-G p.Tyr388Cys missense ADRA1B 2 65582 3.04962E-5 32791 0 NA
5-159399104-C-T p.Pro390Ser missense ADRA1B 8 65510 1.22119E-4 32755 0 6.7815E-5
5-159399105-C-A p.Pro390Gln missense ADRA1B 2 65102 3.0721E-5 32551 0 NA
5-159399106-G-T p.Pro390Pro synonymous ADRA1B 1 65068 1.53685E-5 32534 0 NA
5-159399108-G-A p.Trp391* stop_gained ADRA1B 1 64982 1.53889E-5 32491 0 NA
5-159399115-C-T p.Arg393Arg synonymous ADRA1B 2 64486 3.10145E-5 32243 0 NA
5-159399118-C-T p.Gly394Gly synonymous ADRA1B 1 64162 1.55855E-5 32081 0 NA
5-159399126-T-C p.Leu397Pro missense ADRA1B 1 63920 1.56446E-5 31960 0 NA
5-159399130-G-A p.Glu398Glu synonymous ADRA1B 1 63412 1.57699E-5 31706 0 NA
5-159399136-G-C p.Ser400Ser synonymous ADRA1B 2 62518 3.19908E-5 31259 0 3.3857E-5
5-159399136-G-A p.Ser400Ser synonymous ADRA1B 1 62518 1.59954E-5 31259 0 4.76584E-5
5-159399143-C-T p.Arg403Cys missense ADRA1B 1 61912 1.6152E-5 30956 0 NA
5-159399147-A-G p.Lys404Arg missense ADRA1B 4 61808 6.47165E-5 30904 0 NA
5-159399156-T-C p.Leu407Pro missense ADRA1B 1 60664 1.64842E-5 30332 0 NA
5-159399160-C-T p.Asp408Asp synonymous ADRA1B 1 59482 1.68118E-5 29741 0 1.4751E-5
5-159399160-C-A p.Asp408Glu missense ADRA1B 1 59482 1.68118E-5 29741 0 1.33985E-4
5-159399163-CAGCGGCAGCTGCCTG-C p.Cys413_Ser417del conservative_inframe_deletion ADRA1B 1 59248 1.68782E-5 29624 0 1.51167E-5
5-159399178-G-A p.Leu414Leu synonymous ADRA1B 1 55192 1.81186E-5 27596 0 NA
5-159399193-G-A p.Arg419Arg synonymous ADRA1B 3 50962 5.88674E-5 25481 0 6.68181E-5
5-159399206-G-T p.Ala424Ser missense ADRA1B 1 47512 2.10473E-5 23756 0 NA
5-159399213-C-T p.Pro426Leu missense ADRA1B 5 45414 1.10098E-4 22707 0 2.71602E-4
5-159399214-G-A p.Pro426Pro synonymous ADRA1B 1 45318 2.20663E-5 22659 0 9.69594E-5
5-159399216-G-C p.Ser427Thr missense ADRA1B 1 44882 2.22806E-5 22441 0 NA
5-159399222-G-C p.Gly429Ala missense ADRA1B 3 43990 6.81973E-5 21995 0 6.2422E-4
5-159399233-C-G p.Arg433Gly missense ADRA1B 1 41810 2.39177E-5 20905 0 6.75037E-5
5-159399238-C-T p.Gly434Gly synonymous ADRA1B 9 40496 2.22244E-4 20248 0 1.75026E-4
5-159399238-C-A p.Gly434Gly synonymous ADRA1B 1 40496 2.46938E-5 20248 0 NA
5-159399242-C-G p.Pro436Ala missense ADRA1B 2 40250 4.96894E-5 20125 0 NA
5-159399251-G-T p.Val439Phe missense ADRA1B 2 39974 5.00325E-5 19987 0 6.73129E-5
5-159399251-G-A p.Val439Ile missense ADRA1B 1 39974 2.50163E-5 19987 0 NA
5-159399252-T-G p.Val439Gly missense ADRA1B 1 39778 2.51395E-5 19889 0 NA
5-159399265-C-T p.Ala443Ala synonymous ADRA1B 1 38922 2.56924E-5 19461 0 NA
5-159399268-C-A p.Phe444Leu missense ADRA1B 1 38840 2.57467E-5 19420 0 NA
5-159399271-C-A p.Pro445Pro synonymous ADRA1B 4 38308 1.04417E-4 19154 0 3.56125E-4
5-159399271-C-G p.Pro445Pro synonymous ADRA1B 1 38310 2.61028E-5 19155 0 NA
5-159399272-G-T p.Glu446* stop_gained ADRA1B 2 38400 5.20833E-5 19200 0 NA
5-159399287-G-A p.Gly451Ser missense ADRA1B 1 37798 2.64564E-5 18899 0 NA
5-159399288-G-A p.Gly451Asp missense ADRA1B 2 37830 5.28681E-5 18915 0 NA
5-159399294-TCCTGAGCCTGCCCGCG-T p.Leu456fs frameshift ADRA1B 1 38946 2.56766E-5 19473 0 NA
5-159399294-T-TCCTGAGCCTGCCCGCG p.Pro462fs frameshift ADRA1B 1 38946 2.56766E-5 19473 0 NA
5-159399303-T-TG p.Pro457fs frameshift ADRA1B 1 38840 2.57467E-5 19420 0 NA
5-159399307-C-T p.Pro457Pro synonymous ADRA1B 1 38792 2.57785E-5 19396 0 3.76025E-5
5-159399321-C-G p.Pro462Arg missense ADRA1B 8 38792 2.06228E-4 19396 0 6.34348E-4
5-159399324-G-T p.Gly463Val missense ADRA1B 1 38608 2.59014E-5 19304 0 1.80845E-5
5-159399327-G-A p.Arg464His missense ADRA1B 1 38520 2.59605E-5 19260 0 1.78827E-5
5-159399333-G-A p.Gly466Asp missense ADRA1B 37 38592 9.58748E-4 19296 0 0.00121065
5-159399340-C-G p.His468Gln missense ADRA1B 1 38746 2.58091E-5 19373 0 NA
5-159399345-C-T p.Ser470Leu missense ADRA1B 1 39164 2.55337E-5 19582 0 9.78921E-5
5-159399347-G-T p.Gly471Cys missense ADRA1B 1 39446 2.53511E-5 19723 0 NA
5-159399349-C-T p.Gly471Gly synonymous ADRA1B 1 39464 2.53396E-5 19732 0 3.25119E-5
5-159399350-C-A p.Pro472Thr missense ADRA1B 1 39524 2.53011E-5 19762 0 2.29148E-5
5-159399365-A-G p.Lys477Glu missense ADRA1B 1 39768 2.51458E-5 19884 0 2.88417E-5
5-159399379-G-A p.Glu481Glu synonymous ADRA1B 3 39812 7.53542E-5 19906 0 6.46078E-5
5-159399383-G-A p.Glu483Lys missense ADRA1B 3 39884 7.52181E-5 19942 0 6.44413E-5
5-159399393-G-A p.Gly486Glu missense ADRA1B 2 40020 4.9975E-5 20010 0 NA
5-159399394-G-A p.Gly486Gly synonymous ADRA1B 1 40054 2.49663E-5 20027 0 NA
5-159399400-C-T p.Asp488Asp synonymous ADRA1B 2 40118 4.98529E-5 20059 0 3.2144E-5
5-159399401-G-A p.Gly489Ser missense ADRA1B 1 40124 2.49227E-5 20062 0 NA
5-159399406-C-A p.Gly490Gly synonymous ADRA1B 4 40224 9.94431E-5 20112 0 NA
5-159399409-C-T p.Ala491Ala synonymous ADRA1B 1 40406 2.47488E-5 20203 0 4.47804E-4
5-159399413-A-C p.Asn493His missense ADRA1B 1 40544 2.46646E-5 20272 0 8.98763E-6
5-159399417-G-T p.Gly494Val missense ADRA1B 1 40828 2.4493E-5 20414 0 3.64385E-5
5-159399424-C-T p.Cys496Cys synonymous ADRA1B 5 41086 1.21696E-4 20543 0 1.47256E-4
5-159399430-C-G p.Ala498Ala synonymous ADRA1B 1 41414 2.41464E-5 20707 0 NA
5-159399436-C-G p.Ala500Ala synonymous ADRA1B 3 41732 7.18873E-5 20866 0 1.99574E-4
5-159399443-G-A p.Ala503Thr missense ADRA1B 1 42326 2.36261E-5 21163 0 NA
5-159399448-C-G p.Asn504Lys missense ADRA1B 5 42432 1.17836E-4 21216 0 5.98289E-5
5-159399449-G-T p.Gly505Trp missense ADRA1B 1 42480 2.35405E-5 21240 0 NA
5-159399459-G-A p.Gly508Asp missense ADRA1B 1 42754 2.33896E-5 21377 0 3.2113E-5
5-159399467-A-T p.Ser511Cys missense ADRA1B 1 42998 2.32569E-5 21499 0 NA
5-159399468-G-C p.Ser511Thr missense ADRA1B 2 42942 4.65744E-5 21471 0 2.24994E-4
5-159399473-A-G p.Met513Val missense ADRA1B 2 42898 4.66222E-5 21449 0 4.20636E-5
5-159399477-C-T p.Pro514Leu missense ADRA1B 1 42792 2.33689E-5 21396 0 NA
5-159399478-C-T p.Pro514Pro synonymous ADRA1B 2 42756 4.67771E-5 21378 0 1.10186E-5
5-159399483-C-T p.Ala516Val missense ADRA1B 6 42244 1.42032E-4 21122 0 4.73093E-5
5-159399483-C-A p.Ala516Glu missense ADRA1B 2 42244 4.7344E-5 21122 0 1.18273E-4
5-159399488-G-T p.Gly518Trp missense ADRA1B 6 42274 1.41931E-4 21137 0 3.91972E-5
5-159399526-T-TGGGGAGGAAAACATCGTGGG p.Gln519fs frameshift ADRA1B 1 35600 2.80899E-5 17800 0 NA
5-159399543-T-TG c.*51dupG splice_region ADRA1B 4 30136 1.32732E-4 15068 0 NA
5-159399544-G-GGGGGGGAGGGGAGGGCGGGGCGGA p.Pro514_Leu515insGlyGluGlyGlyAlaGluGlyGly conservative_inframe_insertion ADRA1B 1 31790 3.14564E-5 15895 0 NA
5-159399548-GGGAGGGGAGGGCGGGGC-G c.*50_*66delGGAGGGGAGGGCGGGGC splice_region ADRA1B 1 30316 3.29859E-5 15158 0 NA
5-159399550-G-T c.*51G>T splice_region ADRA1B 1 29166 3.42865E-5 14583 0 3.24423E-5