Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
4-62067052-C-T c.-671C>T 5_prime_UTR_premature_start_codon_gain LPHN3 1 28430 3.51741E-5 14215 0 3.18532E-5
4-62362835-GC-TT c.-173-4_-173-3delGCinsTT splice_region LPHN3 1 53294 1.87638E-5 26647 0 NA
4-62362835-G-A c.-173-4G>A splice_region LPHN3 1 53294 1.87638E-5 26647 0 NA
4-62362839-G-T c.-173G>T splice_region LPHN3 1 54962 1.81944E-5 27481 0 3.3695E-5
4-62362856-T-C c.-156T>C 5_prime_UTR_premature_start_codon_gain LPHN3 1 60106 1.66373E-5 30053 0 NA
4-62362871-T-G c.-141T>G 5_prime_UTR_premature_start_codon_gain LPHN3 1 64290 1.55545E-5 32145 0 NA
4-62363020-A-G p.Pro3Pro synonymous LPHN3 2 82340 2.42895E-5 41170 0 NA
4-62363022-C-T p.Ser4Leu missense LPHN3 2 82326 2.42937E-5 41163 0 6.39386E-5
4-62363023-G-A p.Ser4Ser synonymous LPHN3 4 82336 4.85814E-5 41168 0 2.23642E-4
4-62363024-C-A p.Gln5Lys missense LPHN3 1 82358 1.21421E-5 41179 0 4.19301E-5
4-62363030-C-T p.Leu7Leu synonymous LPHN3 2 82356 2.42848E-5 41178 0 8.39842E-6
4-62363032-A-C p.Leu7Leu synonymous LPHN3 1 82348 1.21436E-5 41174 0 8.40619E-6
4-62363064-A-G p.His18Arg missense+splice_region LPHN3 10 82124 1.21767E-4 41062 0 9.57243E-5
4-62383045-G-A p.Ser23Asn missense LPHN3 3 61042 4.91465E-5 30521 0 2.20835E-5
4-62383045-G-C p.Ser23Thr missense LPHN3 5 61042 8.19108E-5 30521 0 NA
4-62383046-TGAACGACATCC-T p.Glu24fs frameshift LPHN3 3 61036 4.91513E-5 30518 0 7.35943E-6
4-62383075-T-G p.Leu33Trp missense LPHN3 2 61236 3.26605E-5 30618 0 3.18715E-5
4-62383082-C-T p.His35His synonymous LPHN3 6 61266 9.79336E-5 30633 0 6.25E-4
4-62383089-C-T p.Arg38Cys missense LPHN3 2 61264 3.26456E-5 30632 0 6.37389E-5
4-62383089-C-A p.Arg38Ser missense LPHN3 1 61264 1.63228E-5 30632 0 7.25858E-6
4-62383097-A-G p.Pro40Pro synonymous LPHN3 1 61302 1.63127E-5 30651 0 7.23547E-6
4-62383102-G-A p.Gly42Asp missense LPHN3 28 61322 4.56606E-4 30661 0 0.00194765
4-62383110-C-T p.Pro45Ser missense LPHN3 1 61364 1.62962E-5 30682 0 1.44132E-5
4-62383113-C-T p.Pro46Ser missense LPHN3 1 61386 1.62904E-5 30693 0 NA
4-62383120-A-C p.His48Pro missense LPHN3 1 61458 1.62713E-5 30729 0 7.18123E-6
4-62383122-C-T p.Leu49Leu synonymous LPHN3 1 61466 1.62692E-5 30733 0 7.17638E-6
4-62383124-G-A p.Leu49Leu synonymous LPHN3 2 61468 3.25373E-5 30734 0 7.62311E-5
4-62383135-C-T p.Pro53Leu missense LPHN3 48 61560 7.79727E-4 30780 1 0.00376343
4-62383144-AGC-A p.Arg57fs frameshift LPHN3 2 61606 3.24644E-5 30803 0 NA
4-62383149-ACC-A p.Thr58fs frameshift LPHN3 2 61600 3.24675E-5 30800 0 NA
4-62383152-G-C p.Ala59Pro missense LPHN3 1 61628 1.62264E-5 30814 0 7.11845E-6
4-62383154-TGCTCATCGTGGACAAGGGCC-T p.Ala60fs frameshift LPHN3 2 61668 3.24317E-5 30834 0 NA
4-62383159-A-T p.His61Leu missense LPHN3 2 61736 3.2396E-5 30868 0 NA
4-62383161-C-G p.Arg62Gly missense LPHN3 1 61744 1.61959E-5 30872 0 NA
4-62383162-G-T p.Arg62Leu missense LPHN3 1 61758 1.61922E-5 30879 0 3.55119E-5
4-62383168-A-G p.Gln64Arg missense LPHN3 1 61786 1.61849E-5 30893 0 NA
4-62383176-C-G p.Arg67Gly missense LPHN3 1 61774 1.6188E-5 30887 0 1.45222E-4
4-62383177-G-A p.Arg67His missense LPHN3 6 61778 9.7122E-5 30889 0 NA
4-62383178-T-C p.Arg67Arg synonymous LPHN3 1 61778 1.6187E-5 30889 0 7.11015E-6
4-62383194-G-T p.Val73Phe missense LPHN3 2 61616 3.24591E-5 30808 0 7.25584E-5
4-62383205-A-G p.Pro76Pro synonymous LPHN3 1 61468 1.62686E-5 30734 0 2.14715E-5
4-62383210-C-T p.Ala78Val missense LPHN3 1 61338 1.63031E-5 30669 0 3.18674E-5
4-62383240-C-A c.259+4C>A splice_region LPHN3 1 60332 1.6575E-5 30166 0 NA
4-62383241-G-T c.259+5G>T splice_region LPHN3 1 60330 1.65755E-5 30165 0 NA
4-62452945-C-G p.Ala19Gly missense+splice_region LPHN3 2 79406 2.5187E-5 39703 0 5.8257E-5
4-62452953-C-T p.Arg22Cys missense LPHN3 2 79654 2.51086E-5 39827 0 NA
4-62452957-C-T p.Ala23Val missense LPHN3 1 79730 1.25423E-5 39865 0 1.53841E-5
4-62452961-A-G p.Pro24Pro synonymous LPHN3 1 79812 1.25294E-5 39906 0 0.00125
4-62452966-C-T p.Pro26Leu missense LPHN3 2 79920 2.5025E-5 39960 0 1.66984E-5
4-62452991-A-G p.Leu34Leu synonymous LPHN3 1 80286 1.24555E-5 40143 0 6.6056E-5
4-62453004-T-C p.Tyr39His missense LPHN3 2 80424 2.48682E-5 40212 0 4.08614E-6
4-62453011-T-C p.Ile41Thr missense LPHN3 1 80508 1.24211E-5 40254 0 NA
4-62453019-C-T p.Arg44Cys missense LPHN3 1 80598 1.24073E-5 40299 0 9.76257E-6
4-62453037-G-A p.Val50Ile missense LPHN3 8 80856 9.89413E-5 40428 0 3.18573E-5
4-62453055-G-A p.Ala56Thr missense LPHN3 1 81066 1.23356E-5 40533 0 NA
4-62453069-G-A p.Arg60Arg synonymous LPHN3 24 81236 2.95436E-4 40618 0 1.91168E-4
4-62453099-T-C p.Pro70Pro synonymous LPHN3 1 81390 1.22865E-5 40695 0 1.69202E-5
4-62453105-G-T p.Gln72His missense LPHN3 1 81394 1.22859E-5 40697 0 6.37267E-5
4-62453126-T-C p.Tyr79Tyr synonymous LPHN3 1 81298 1.23004E-5 40649 0 NA
4-62453141-T-C p.Tyr84Tyr synonymous LPHN3 1 81150 1.23229E-5 40575 0 NA
4-62453142-A-G p.Lys85Glu missense LPHN3 2 81140 2.46488E-5 40570 0 NA
4-62542587-G-A p.Val105Ile missense LPHN3 1 82656 1.20983E-5 41328 0 NA
4-62542598-C-T p.Asp108Asp synonymous LPHN3 2 82662 2.41949E-5 41331 0 8.28569E-6
4-62542607-A-G p.Pro111Pro synonymous LPHN3 155 82652 0.00187533 41326 0 0.00453172
4-62542650-T-C p.Tyr126His missense LPHN3 1 82466 1.21262E-5 41233 0 NA
4-62596335-A-G c.380-5A>G splice_region LPHN3 1 61920 1.61499E-5 30960 0 3.19428E-5
4-62596336-A-G c.380-4A>G splice_region LPHN3 1 61932 1.61467E-5 30966 0 NA
4-62598511-G-A p.Ser145Asn missense LPHN3 1 81412 1.22832E-5 40706 0 2.55846E-5
4-62598530-C-T p.Ser151Ser synonymous LPHN3 5 81724 6.11815E-5 40862 0 1.62496E-4
4-62598539-A-G p.Gln154Gln synonymous LPHN3 2 81870 2.4429E-5 40935 0 6.37146E-5
4-62598548-G-A p.Ala157Ala synonymous LPHN3 533 81886 0.00650905 40943 5 0.023125
4-62598548-G-C p.Ala157Ala synonymous LPHN3 2 81896 2.44212E-5 40948 0 1.22479E-5
4-62598552-T-G p.Cys159Gly missense LPHN3 1 81884 1.22124E-5 40942 0 4.06431E-6
4-62598570-G-C p.Ala165Pro missense LPHN3 1 81970 1.21996E-5 40985 0 NA
4-62598576-G-C p.Asp167His missense LPHN3 1 82050 1.21877E-5 41025 0 4.02956E-6
4-62598580-A-G p.Lys168Arg missense LPHN3 3 82102 3.65399E-5 41051 0 8.53723E-6
4-62598589-A-G p.Tyr171Cys missense LPHN3 1 82180 1.21684E-5 41090 0 NA
4-62598600-A-G p.Thr175Ala missense LPHN3 1 82226 1.21616E-5 41113 0 8.38532E-6
4-62598601-C-G p.Thr175Ser missense LPHN3 3 82232 3.64821E-5 41116 0 3.18695E-5
4-62598608-C-T p.Tyr177Tyr synonymous LPHN3 1 82270 1.21551E-5 41135 0 4.02139E-6
4-62598619-C-G p.Thr181Ser missense LPHN3 2 82280 2.43072E-5 41140 0 1.20642E-5
4-62598629-G-A p.Glu184Glu synonymous LPHN3 1 82270 1.21551E-5 41135 0 1.66736E-5
4-62598632-T-C p.Tyr185Tyr synonymous LPHN3 1 82258 1.21569E-5 41129 0 NA
4-62598643-A-G p.Asp189Gly missense LPHN3 1 82198 1.21657E-5 41099 0 NA
4-62598647-C-T p.Asp190Asp synonymous LPHN3 1 82190 1.21669E-5 41095 0 8.32709E-6
4-62598666-A-G p.Thr197Ala missense LPHN3 1 82040 1.21892E-5 41020 0 6.37349E-5
4-62598675-T-C p.Tyr200His missense LPHN3 3 81924 3.66193E-5 40962 0 NA
4-62598677-C-T p.Tyr200Tyr synonymous LPHN3 1 81882 1.22127E-5 40941 0 NA
4-62598689-C-T p.His204His synonymous LPHN3 54380 81092 0.670596 40546 18565 0.711984
4-62598714-G-T p.Val213Leu missense LPHN3 2 81290 2.46033E-5 40645 0 1.66631E-5
4-62598718-A-G p.Tyr214Cys missense LPHN3 4 81258 4.92259E-5 40629 0 7.49913E-5
4-62598771-G-A p.Asp232Asn missense LPHN3 1 81100 1.23305E-5 40550 0 8.36386E-6
4-62598785-G-T p.Arg236Ser missense LPHN3 1 81286 1.23022E-5 40643 0 NA
4-62598828-G-A p.Asp251Asn missense LPHN3 6 81846 7.33084E-5 40923 0 2.28724E-4
4-62598844-G-A p.Arg256Gln missense LPHN3 2 82044 2.43772E-5 41022 0 4.04498E-6
4-62598845-A-T p.Arg256Arg synonymous LPHN3 2 82048 2.4376E-5 41024 0 NA
4-62598854-C-T p.Gly259Gly synonymous LPHN3 1 82108 1.21791E-5 41054 0 4.04514E-6
4-62598913-A-G p.Glu279Gly missense LPHN3 1 81996 1.21957E-5 40998 0 NA
4-62598944-A-G p.Gln289Gln synonymous LPHN3 28 81694 3.42742E-4 40847 0 0.00100705
4-62598951-C-G p.Pro292Ala missense LPHN3 1 81662 1.22456E-5 40831 0 3.18573E-5
4-62598959-C-T p.Thr294Thr synonymous LPHN3 1 81658 1.22462E-5 40829 0 1.61293E-5
4-62598959-C-A p.Thr294Thr synonymous LPHN3 2 81658 2.44924E-5 40829 0 NA
4-62598968-C-A p.Ile297Ile synonymous LPHN3 1 81602 1.22546E-5 40801 0 1.20974E-5
4-62598968-C-T p.Ile297Ile synonymous LPHN3 1 81602 1.22546E-5 40801 0 8.38645E-6
4-62598995-T-C p.Asp306Asp synonymous LPHN3 1 81822 1.22217E-5 40911 0 NA
4-62599049-A-G p.Lys324Lys synonymous LPHN3 2 82358 2.42842E-5 41179 0 NA
4-62599052-T-G p.Ser325Ser synonymous LPHN3 1 82386 1.2138E-5 41193 0 4.02279E-6
4-62599072-A-G p.Asn332Ser missense LPHN3 7 82480 8.48691E-5 41240 0 1.59236E-4
4-62599073-T-C p.Asn332Asn synonymous LPHN3 39 82492 4.72773E-4 41246 0 4.45831E-4
4-62599108-A-G p.Asn344Ser missense LPHN3 2 82574 2.42207E-5 41287 0 4.01913E-6
4-62599111-C-G p.Thr345Ser missense LPHN3 1 82578 1.21098E-5 41289 0 NA
4-62599112-T-C p.Thr345Thr synonymous LPHN3 1 82584 1.21089E-5 41292 0 3.18471E-5
4-62599120-G-A p.Ser348Asn missense LPHN3 1 82564 1.21118E-5 41282 0 NA
4-62599121-C-G p.Ser348Arg missense LPHN3 1 82568 1.21112E-5 41284 0 NA
4-62599123-A-G p.Lys349Arg missense LPHN3 3 82566 3.63346E-5 41283 0 4.1684E-5
4-62599124-G-T p.Lys349Asn missense LPHN3 7 82566 8.47807E-5 41283 0 3.18471E-5
4-62599131-T-G p.Leu352Val missense LPHN3 1 82566 1.21115E-5 41283 0 NA
4-62599134-G-T p.Val353Leu missense LPHN3 1 82564 1.21118E-5 41282 0 NA
4-62599166-C-T p.Tyr363Tyr synonymous LPHN3 2 82540 2.42307E-5 41270 0 8.36037E-6
4-62599170-G-T p.Ala365Ser missense LPHN3 1 82504 1.21206E-5 41252 0 8.36218E-6
4-62599223-T-C p.Tyr382Tyr synonymous LPHN3 1 82180 1.21684E-5 41090 0 1.69463E-5
4-62599226-C-T p.His383His synonymous LPHN3 8 82100 9.74421E-5 41050 0 1.18819E-4
4-62599227-G-A p.Val384Ile missense LPHN3 5 82086 6.09117E-5 41043 0 4.77677E-4
4-62599229-C-T p.Val384Val synonymous LPHN3 2 82046 2.43766E-5 41023 0 6.3678E-5
4-62599237-A-G p.Tyr387Cys missense LPHN3 1 81942 1.22038E-5 40971 0 4.0405E-6
4-62599238-T-C p.Tyr387Tyr synonymous LPHN3 10 81928 1.22058E-4 40964 0 0.00151057
4-62599257-C-T p.Leu394Leu synonymous LPHN3 1 81626 1.2251E-5 40813 0 4.06359E-6
4-62599260-G-T p.Asp395Tyr missense LPHN3 1 81564 1.22603E-5 40782 0 3.1841E-5
4-62599262-T-G p.Asp395Glu missense LPHN3 1 81518 1.22672E-5 40759 0 NA
4-62599273-G-GACAAAGAAAAACTGTTGGAAGGGAAACAGT c.1195+1_1195+2insACAAAGAAAAACTGTTGGAAGGGAAACAGT splice_donor LPHN3 2 81108 2.46585E-5 40554 1 NA
4-62679533-C-T p.Ala401Val missense LPHN3 1 79408 1.25932E-5 39704 0 NA
4-62679547-G-A p.Val406Ile missense LPHN3 1 79408 1.25932E-5 39704 0 4.05328E-6
4-62679549-T-G p.Val406Val synonymous LPHN3 8 79408 1.00746E-4 39704 0 4.45868E-5
4-62679556-A-C p.Ile409Leu missense LPHN3 2 79380 2.51953E-5 39690 0 NA
4-62679564-G-A p.Pro411Pro synonymous LPHN3 5 79314 6.30406E-5 39657 0 5.18135E-4
4-62679568-A-G p.Ile413Val missense LPHN3 2 79326 2.52124E-5 39663 0 4.05357E-6
4-62679576-T-C p.Leu415Leu synonymous LPHN3 2 79292 2.52232E-5 39646 0 NA
4-62679598-T-C p.Ser423Pro missense LPHN3 1 79224 1.26224E-5 39612 0 NA
4-62758373-G-T c.1277-1G>T splice_acceptor LPHN3 2 82670 2.41926E-5 41335 0 NA
4-62758378-C-T p.Ile427Ile synonymous LPHN3 1 82716 1.20896E-5 41358 0 3.18471E-5
4-62758393-T-C p.Pro432Pro synonymous LPHN3 1 82762 1.20828E-5 41381 0 NA
4-62758396-T-C p.Leu433Leu synonymous LPHN3 1 82774 1.20811E-5 41387 0 6.36983E-5
4-62758398-G-T p.Gly434Val missense LPHN3 3 82774 3.62433E-5 41387 0 1.27453E-4
4-62758407-G-A p.Ser437Asn missense LPHN3 1 82778 1.20805E-5 41389 0 3.18431E-5
4-62758416-C-T p.Thr440Ile missense LPHN3 1 82800 1.20773E-5 41400 0 NA
4-62758416-C-A p.Thr440Asn missense LPHN3 1 82800 1.20773E-5 41400 0 1.65629E-5
4-62758425-C-T p.Thr443Ile missense LPHN3 84 82790 0.00101462 41395 0 0.008125
4-62758439-A-G p.Thr448Ala missense LPHN3 1 82806 1.20764E-5 41403 0 1.65618E-5
4-62758453-A-C p.Gly452Gly synonymous LPHN3 1 82786 1.20793E-5 41393 0 NA
4-62758467-C-T p.Pro457Leu missense LPHN3 2 82770 2.41633E-5 41385 0 2.00663E-5
4-62758468-G-A p.Pro457Pro synonymous LPHN3 3 82770 3.6245E-5 41385 0 6.25E-4
4-62758468-G-T p.Pro457Pro synonymous LPHN3 11 82770 1.32898E-4 41385 0 1.91266E-4
4-62758477-A-G p.Ser460Ser synonymous LPHN3 1 82758 1.20834E-5 41379 0 NA
4-62758490-C-T p.Arg465Trp missense LPHN3 1 82700 1.20919E-5 41350 0 1.65675E-5
4-62758491-G-A p.Arg465Gln missense LPHN3 972 82680 0.0117562 41340 5 0.0117793
4-62758499-A-G p.Ser468Gly missense LPHN3 2 82670 2.41926E-5 41335 0 3.31417E-5
4-62758505-C-G p.Pro470Ala missense LPHN3 1 82628 1.21024E-5 41314 0 8.28734E-6
4-62758510-T-A p.Ser471Ser synonymous LPHN3 4 82610 4.84203E-5 41305 0 5.6238E-5
4-62758514-G-A p.Ala473Thr missense LPHN3 1 82598 1.21068E-5 41299 0 NA
4-62758520-G-A p.Glu475Lys missense LPHN3 3 82560 3.63372E-5 41280 0 3.1904E-5
4-62758523-G-A p.Val476Ile missense LPHN3 1 82550 1.21139E-5 41275 0 9.56938E-5
4-62758531-T-C p.Asp478Asp synonymous LPHN3 4 82530 4.84672E-5 41265 0 1.91388E-4
4-62758561-G-A p.Ser488Ser synonymous LPHN3 7 82406 8.49453E-5 41203 0 9.56389E-5
4-62758579-C-T p.Leu494Leu synonymous LPHN3 1 82404 1.21353E-5 41202 0 3.18756E-5
4-62758583-G-A p.Glu496Lys missense LPHN3 12 82446 1.4555E-4 41223 0 2.5481E-4
4-62758586-A-G p.Ser497Gly missense LPHN3 3 82440 3.63901E-5 41220 0 5.3755E-5
4-62758594-G-A p.Glu499Glu synonymous LPHN3 1 82524 1.21177E-5 41262 0 9.0886E-6
4-62758596-C-T p.Ala500Val missense LPHN3 114 82526 0.00138138 41263 0 0.00159307
4-62758617-T-A p.Met507Lys missense LPHN3 1 82588 1.21083E-5 41294 0 5.03525E-4
4-62758638-G-A p.Gly514Glu missense LPHN3 1 82592 1.21077E-5 41296 0 3.1841E-5
4-62758639-A-G p.Gly514Gly synonymous LPHN3 10 82586 1.21086E-4 41293 0 0.00125
4-62758666-A-G p.Ala523Ala synonymous LPHN3 2 82518 2.42371E-5 41259 0 3.22758E-5
4-62758683-C-G c.1579+7C>G splice_region LPHN3 1 82290 1.21521E-5 41145 0 1.93678E-5
4-62761450-T-G p.Gly527Gly splice_region+synonymous LPHN3 2 81758 2.44624E-5 40879 0 NA
4-62761464-T-C p.Leu2Pro missense LPHN3 179 82028 0.00218218 41014 1 0.00731738
4-62761465-A-G p.Leu2Leu synonymous LPHN3 1 82046 1.21883E-5 41023 0 4.28879E-6
4-62761469-C-T p.Leu4Phe missense LPHN3 1 82058 1.21865E-5 41029 0 NA
4-62761495-C-T p.Pro12Pro synonymous LPHN3 1 82130 1.21758E-5 41065 0 4.2308E-6
4-62761498-A-C p.Gln13His missense LPHN3 1 82138 1.21746E-5 41069 0 4.2193E-6
4-62761498-A-G p.Gln13Gln synonymous LPHN3 1 82138 1.21746E-5 41069 0 NA
4-62761510-C-T p.Leu17Leu synonymous LPHN3 3 82138 3.65239E-5 41069 0 3.19E-5
4-62761522-T-C p.Ser21Ser synonymous LPHN3 1 82054 1.21871E-5 41027 0 NA
4-62761525-T-A p.Ser22Ser synonymous LPHN3 1 82024 1.21916E-5 41012 0 NA
4-62761539-A-G p.His27Arg missense LPHN3 1 81744 1.22333E-5 40872 0 4.58968E-6
4-62761545-C-T p.Thr29Ile missense LPHN3 2 81796 2.44511E-5 40898 0 0.00100705
4-62775284-T-A p.Ser34Thr missense LPHN3 3 82284 3.64591E-5 41142 0 4.09386E-6
4-62775303-A-G p.Asn40Ser missense LPHN3 1 82382 1.21386E-5 41191 0 NA
4-62775317-C-G p.Leu45Val missense LPHN3 2 82414 2.42677E-5 41207 0 8.9308E-6
4-62775319-G-T p.Leu45Leu synonymous LPHN3 1 82428 1.21318E-5 41214 0 3.18451E-5
4-62775327-A-G p.Gln48Arg missense LPHN3 4 82478 4.84978E-5 41239 0 2.68783E-5
4-62775330-C-T p.Thr49Ile missense LPHN3 1 82478 1.21244E-5 41239 0 NA
4-62775331-A-G p.Thr49Thr synonymous LPHN3 1 82482 1.21239E-5 41241 0 2.86606E-4
4-62775333-G-T p.Arg50Ile missense LPHN3 33 82486 4.00068E-4 41243 0 8.9835E-4
4-62775361-C-T p.Thr59Thr synonymous LPHN3 1 82504 1.21206E-5 41252 0 NA
4-62775372-G-A p.Arg63Gln missense LPHN3 2 82510 2.42395E-5 41255 0 3.27571E-5
4-62775372-G-C p.Arg63Pro missense LPHN3 2 82510 2.42395E-5 41255 0 NA
4-62775378-T-A p.Met65Lys missense LPHN3 1 82516 1.21189E-5 41258 0 NA
4-62775378-T-C p.Met65Thr missense LPHN3 2 82516 2.42377E-5 41258 1 8.25471E-6
4-62775395-C-T p.Leu71Phe missense LPHN3 2 82520 2.42365E-5 41260 0 NA
4-62775400-A-G p.Leu72Leu synonymous LPHN3 1 82508 1.212E-5 41254 0 8.7379E-6
4-62775414-G-A p.Arg77Gln missense LPHN3 2 82500 2.42424E-5 41250 0 2.42474E-5
4-62775418-C-A p.Asn78Lys missense LPHN3 3 82494 3.63663E-5 41247 0 3.18898E-5
4-62775429-G-A p.Gly82Asp missense LPHN3 2 82482 2.42477E-5 41241 0 NA
4-62775438-A-T p.Asp85Val missense LPHN3 1 82456 1.21277E-5 41228 0 NA
4-62775450-G-A p.Arg89Gln missense LPHN3 1 82386 1.2138E-5 41193 0 NA
4-62775471-C-T c.279+8C>T splice_region LPHN3 1 81986 1.21972E-5 40993 0 3.65684E-5
4-62778430-G-A c.1870-7G>A splice_region LPHN3 6 81890 7.3269E-5 40945 0 NA
4-62778442-GA-G p.Arg627fs frameshift LPHN3 1 81892 1.22112E-5 40946 0 4.02133E-6
4-62778447-G-T p.Arg627Ile missense LPHN3 1 81882 1.22127E-5 40941 0 4.02156E-6
4-62778451-G-A p.Glu628Glu synonymous LPHN3 1 81862 1.22157E-5 40931 0 6.37227E-5
4-62778452-C-A p.Arg629Ser missense LPHN3 5 81866 6.10754E-5 40933 0 1.20673E-5
4-62778454-C-T p.Arg629Arg synonymous LPHN3 2 81890 2.4423E-5 40945 0 NA
4-62778469-T-C p.Tyr634Tyr synonymous LPHN3 1 81868 1.22148E-5 40934 0 NA
4-62778482-T-A c.1908+7T>A splice_region LPHN3 2 81820 2.44439E-5 40910 0 NA
4-62800551-C-G c.280-7C>G splice_region LPHN3 2 81924 2.44129E-5 40962 0 NA
4-62800554-G-A c.280-4G>A splice_region LPHN3 52790 74942 0.704411 37471 18422 0.744796
4-62800562-T-C p.Met95Thr missense LPHN3 2 82156 2.43439E-5 41078 0 2.53498E-5
4-62800566-C-T p.Val96Val synonymous LPHN3 2 82180 2.43368E-5 41090 0 1.61298E-5
4-62800566-C-G p.Val96Val synonymous LPHN3 2 82182 2.43362E-5 41091 0 3.18512E-5
4-62800577-A-G p.Asn100Ser missense LPHN3 7 82290 8.5065E-5 41145 0 6.36983E-5
4-62800608-A-G p.Ala110Ala synonymous LPHN3 2 82428 2.42636E-5 41214 0 NA
4-62800617-C-G p.Asp113Glu missense LPHN3 1 82390 1.21374E-5 41195 0 NA
4-62800620-G-C p.Leu114Leu synonymous LPHN3 3 82424 3.63972E-5 41212 0 1.66356E-5
4-62800624-A-G p.Thr116Ala missense LPHN3 873 82408 0.0105936 41204 8 0.0078319
4-62800625-C-T p.Thr116Met missense LPHN3 3 82416 3.64007E-5 41208 0 6.36821E-5
4-62800626-G-A p.Thr116Thr synonymous LPHN3 607 82404 0.00736615 41202 20 0.0169405
4-62800628-G-C p.Ser117Thr missense LPHN3 3 82418 3.63998E-5 41209 0 4.01694E-6
4-62800639-C-T p.Arg121Cys missense LPHN3 1 82400 1.21359E-5 41200 0 2.49215E-5
4-62800642-G-A p.Ala122Thr missense LPHN3 1 82408 1.21347E-5 41204 0 8.30496E-5
4-62800644-G-A p.Ala122Ala synonymous LPHN3 7 82410 8.49411E-5 41205 0 2.40804E-4
4-62800668-G-A p.Val130Val synonymous LPHN3 5 82370 6.07017E-5 41185 0 1.65928E-5
4-62800672-G-A p.Glu132Lys missense LPHN3 1 82376 1.21395E-5 41188 0 NA
4-62800728-T-C p.Asn150Asn synonymous LPHN3 58018 80290 0.722606 40145 20942 0.747526
4-62800738-A-G p.Ile154Val missense LPHN3 1 82138 1.21746E-5 41069 0 8.32542E-6
4-62800745-A-G c.463+4A>G splice_region LPHN3 5 82030 6.09533E-5 41015 0 NA
4-62801643-T-A p.Leu156Met missense+splice_region LPHN3 1 81782 1.22276E-5 40891 0 6.25E-4
4-62801664-A-G p.Thr163Ala missense LPHN3 1 82062 1.21859E-5 41031 0 NA
4-62801675-C-T p.Asn166Asn synonymous LPHN3 1 82158 1.21717E-5 41079 0 3.18471E-5
4-62801678-A-G p.Leu167Leu synonymous LPHN3 1 82192 1.21666E-5 41096 0 3.52696E-5
4-62801682-G-A p.Asp169Asn missense LPHN3 35 82234 4.25615E-4 41117 1 0.00136969
4-62801697-G-A p.Glu174Lys missense LPHN3 2 82308 2.4299E-5 41154 0 NA
4-62801711-T-C p.His178His synonymous LPHN3 1 82362 1.21415E-5 41181 0 4.1402E-6
4-62801712-G-A p.Gly179Arg missense LPHN3 2 82360 2.42836E-5 41180 0 4.14038E-6
4-62801713-G-T p.Gly179Val missense LPHN3 3 82360 3.64254E-5 41180 0 6.36862E-5
4-62801723-C-A p.Ile182Ile synonymous LPHN3 1 82372 1.214E-5 41186 0 NA
4-62801731-C-T p.Ser185Phe missense LPHN3 1 82372 1.214E-5 41186 0 NA
4-62801733-G-T p.Ala186Ser missense LPHN3 1 82364 1.21412E-5 41182 0 NA
4-62801758-G-T p.Arg194Leu missense LPHN3 1 82338 1.21451E-5 41169 0 4.11096E-6
4-62801763-G-C p.Gly196Arg missense+splice_region LPHN3 1 82336 1.21454E-5 41168 0 NA
4-62812633-A-G p.Gly196Gly splice_region+synonymous LPHN3 1 82650 1.20992E-5 41325 0 4.01423E-6
4-62812659-A-T p.Tyr205Phe missense LPHN3 1 82714 1.20899E-5 41357 0 NA
4-62812663-C-A p.Asn206Lys missense LPHN3 6 82730 7.25251E-5 41365 0 6.36902E-5
4-62812686-C-T p.Thr214Met missense LPHN3 1 82756 1.20837E-5 41378 0 NA
4-62812688-G-A p.Glu215Lys missense LPHN3 1 82756 1.20837E-5 41378 0 1.20365E-5
4-62812698-G-A p.Ser218Asn missense LPHN3 1 82754 1.2084E-5 41377 0 1.65607E-5
4-62812700-A-G p.Met219Val missense LPHN3 1 82750 1.20846E-5 41375 0 1.15925E-4
4-62812710-G-A p.Gly222Glu missense LPHN3 3 82750 3.62538E-5 41375 0 1.48447E-4
4-62812713-C-T p.Thr223Met missense LPHN3 15 82744 1.81282E-4 41372 0 6.25E-4
4-62812714-G-A p.Thr223Thr synonymous LPHN3 129 82748 0.00155895 41374 0 0.0028353
4-62812714-G-C p.Thr223Thr synonymous LPHN3 1 82748 1.20849E-5 41374 0 2.00611E-5
4-62812719-C-G p.Ala225Gly missense LPHN3 1 82748 1.20849E-5 41374 0 8.28034E-6
4-62812730-A-G p.Asn229Asp missense LPHN3 3 82748 3.62547E-5 41374 0 NA
4-62812735-T-C p.His230His synonymous LPHN3 124 82748 0.00149853 41374 1 0.00352467
4-62812738-T-C p.Ser231Ser synonymous LPHN3 24 82748 2.90037E-4 41374 0 5.41298E-4
4-62812739-G-A p.Val232Ile missense LPHN3 3 82752 3.62529E-5 41376 0 3.18512E-5
4-62812747-C-T p.Val234Val synonymous LPHN3 8 82748 9.66791E-5 41374 0 6.37349E-5
4-62812763-A-G p.Thr240Ala missense LPHN3 1 82748 1.20849E-5 41374 0 NA
4-62812764-C-T p.Thr240Met missense LPHN3 147 82740 0.00177665 41370 0 0.00375
4-62812772-A-G p.Ile243Val missense LPHN3 1 82722 1.20887E-5 41361 0 NA
4-62812786-C-T p.Phe247Phe synonymous LPHN3 1 82698 1.20922E-5 41349 0 1.65631E-5
4-62812797-T-G p.Val251Gly missense LPHN3 1 82646 1.20998E-5 41323 0 NA
4-62812798-T-A p.Val251Val synonymous LPHN3 1 82646 1.20998E-5 41323 0 NA
4-62812807-T-C p.Ala254Ala synonymous LPHN3 1 82606 1.21057E-5 41303 0 4.01378E-6
4-62812817-G-A p.Val258Ile missense LPHN3 2 82550 2.42277E-5 41275 0 NA
4-62812822-T-C p.Phe259Phe synonymous LPHN3 1 82528 1.21171E-5 41264 0 8.29394E-6
4-62812830-A-G p.Lys262Arg missense LPHN3 1 82492 1.21224E-5 41246 0 3.32127E-5
4-62813827-G-A p.Glu269Lys missense LPHN3 1 82404 1.21353E-5 41202 0 NA
4-62813838-C-T p.Asn272Asn synonymous LPHN3 3 82454 3.63839E-5 41227 0 3.18634E-5
4-62813840-C-G p.Pro273Arg missense LPHN3 2 82446 2.42583E-5 41223 0 4.0405E-6
4-62813858-G-A p.Ser279Asn missense LPHN3 2 82470 2.42512E-5 41235 0 NA
4-62813859-C-G p.Ser279Arg missense LPHN3 3 82466 3.63786E-5 41233 0 NA
4-62813865-C-T p.Ser281Ser synonymous LPHN3 1 82476 1.21247E-5 41238 0 1.75939E-5
4-62813870-G-A p.Arg283His missense LPHN3 25 82486 3.03082E-4 41243 0 0.00125
4-62813870-G-T p.Arg283Leu missense LPHN3 6 82486 7.27396E-5 41243 0 3.18593E-5
4-62813873-C-A p.Thr284Lys missense LPHN3 1 82480 1.21242E-5 41240 0 6.37024E-5
4-62813877-G-A p.Met285Ile missense LPHN3 1 82492 1.21224E-5 41246 0 NA
4-62813878-A-T p.Thr286Ser missense LPHN3 2 82488 2.4246E-5 41244 0 8.61104E-6
4-62813880-A-G p.Thr286Thr synonymous LPHN3 1 82486 1.21233E-5 41243 0 8.5952E-6
4-62813888-G-T p.Trp289Leu missense LPHN3 1 82472 1.21253E-5 41236 0 NA
4-62813893-A-T p.Thr291Ser missense LPHN3 3 82468 3.63777E-5 41234 0 3.1839E-5
4-62813901-C-G p.Gly293Gly synonymous LPHN3 2 82496 2.42436E-5 41248 0 1.01614E-4
4-62813915-C-A p.Thr298Lys missense LPHN3 1 82486 1.21233E-5 41243 0 8.38617E-6
4-62813932-A-G p.Thr304Ala missense LPHN3 1 82480 1.21242E-5 41240 0 6.36821E-5
4-62813934-T-C p.Thr304Thr synonymous LPHN3 1 82486 1.21233E-5 41243 0 NA
4-62813935-A-T p.Thr305Ser missense LPHN3 1 82488 1.2123E-5 41244 0 6.36821E-5
4-62813937-A-G p.Thr305Thr synonymous LPHN3 2 82488 2.4246E-5 41244 0 2.00682E-5
4-62813942-C-T p.Ser307Phe missense LPHN3 1 82470 1.21256E-5 41235 0 NA
4-62813953-C-G p.Leu311Val missense LPHN3 1 82458 1.21274E-5 41229 0 NA
4-62813980-C-T p.His320Tyr missense LPHN3 1 82432 1.21312E-5 41216 0 NA
4-62813986-G-A p.Glu322Lys missense LPHN3 1 82422 1.21327E-5 41211 0 NA
4-62813988-A-T p.Glu322Asp missense LPHN3 1 82414 1.21339E-5 41207 0 3.1841E-5
4-62813993-A-C p.Lys324Thr missense+splice_region LPHN3 1 82410 1.21345E-5 41205 0 NA
4-62845276-T-C c.973-5T>C splice_region LPHN3 8 82640 9.68054E-5 41320 0 3.18451E-5
4-62845292-G-A p.Ala328Ala synonymous LPHN3 2 82804 2.41534E-5 41402 0 0.00100705
4-62845296-C-T p.His330Tyr missense LPHN3 1 82822 1.20741E-5 41411 0 NA
4-62845299-G-A p.Asp331Asn missense LPHN3 1 82826 1.20735E-5 41413 0 6.25E-4
4-62845305-C-A p.Leu333Ile missense LPHN3 2 82840 2.41429E-5 41420 0 2.48451E-5
4-62845322-G-A p.Thr338Thr synonymous LPHN3 2 82862 2.41365E-5 41431 0 3.31257E-5
4-62845364-C-T p.Cys352Cys synonymous LPHN3 1 82868 1.20674E-5 41434 0 1.20402E-5
4-62845386-C-T p.Arg360Trp missense LPHN3 2 82834 2.41447E-5 41417 0 6.37796E-5
4-62845387-G-A p.Arg360Gln missense LPHN3 4 82824 4.82952E-5 41412 0 4.14168E-5
4-62845388-G-C p.Arg360Arg synonymous LPHN3 74229 82702 0.897548 41351 33583 0.901875
4-62845388-G-T p.Arg360Arg synonymous LPHN3 31 82820 3.74306E-4 41410 0 4.17215E-4
4-62845391-G-A p.Gly361Gly synonymous LPHN3 1 82820 1.20744E-5 41410 0 8.28253E-6
4-62845404-C-T p.Arg366Cys missense LPHN3 9 82818 1.08672E-4 41409 0 5.03525E-4
4-62845420-A-AT p.Lys371fs frameshift LPHN3 1 82834 1.20723E-5 41417 0 NA
4-62845421-G-GAATAAAGT p.Leu373fs frameshift LPHN3 1 82822 1.20741E-5 41411 0 NA
4-62845432-T-G p.Ile375Ser missense LPHN3 2 82790 2.41575E-5 41395 0 6.62625E-5
4-62845433-C-T p.Ile375Ile synonymous LPHN3 4 82788 4.83162E-5 41394 0 1.27413E-4
4-62845437-C-A p.Leu377Ile missense LPHN3 1 82778 1.20805E-5 41389 0 8.28281E-6
4-62845439-C-T p.Leu377Leu synonymous LPHN3 1 82764 1.20825E-5 41382 0 1.2039E-5
4-62845444-T-A p.Val379Glu missense LPHN3 1 82738 1.20863E-5 41369 0 NA
4-62845445-A-G p.Val379Val synonymous LPHN3 1 82738 1.20863E-5 41369 0 3.18512E-5
4-62845452-C-T p.Leu382Leu synonymous LPHN3 1 82690 1.20934E-5 41345 0 1.20428E-5
4-62845461-C-G p.Leu385Val missense LPHN3 1054 82650 0.0127526 41325 6 0.0131181
4-62845477-G-A p.Arg390Gln missense LPHN3 7 82496 8.48526E-5 41248 0 6.37064E-5
4-62845488-C-G p.Pro394Ala missense+splice_region LPHN3 1 82356 1.21424E-5 41178 0 6.36862E-5
4-62845490-A-G p.Pro394Pro splice_region+synonymous LPHN3 45581 72662 0.627302 36331 14319 0.653535
4-62845498-A-G c.1182+8A>G splice_region LPHN3 2 82140 2.43487E-5 41070 0 3.18654E-5
4-62849101-A-T p.Ile395Phe missense+splice_region LPHN3 1 82758 1.20834E-5 41379 0 6.03704E-5
4-62849105-C-T p.Ala396Val missense LPHN3 1 82756 1.20837E-5 41378 0 4.0222E-6
4-62849106-C-A p.Ala396Ala synonymous LPHN3 1 82762 1.20828E-5 41381 0 NA
4-62849106-C-T p.Ala396Ala synonymous LPHN3 3 82762 3.62485E-5 41381 0 1.694E-5
4-62849117-T-C p.Phe400Ser missense LPHN3 1 82766 1.20823E-5 41383 0 NA
4-62849137-T-A p.Phe407Ile missense LPHN3 1 82776 1.20808E-5 41388 0 NA
4-62849161-A-G p.Met415Val missense LPHN3 1 82782 1.20799E-5 41391 0 8.29339E-6
4-62849165-T-C p.Phe416Ser missense LPHN3 19 82778 2.2953E-4 41389 0 1.16086E-4
4-62849175-G-C p.Gly419Gly synonymous LPHN3 1 82772 1.20814E-5 41386 0 NA
4-62849178-G-C p.Val420Val synonymous LPHN3 2 82768 2.41639E-5 41384 0 6.36821E-5
4-62849178-G-A p.Val420Val synonymous LPHN3 1 82768 1.2082E-5 41384 0 5.04032E-4
4-62849180-A-G p.Gln421Arg missense LPHN3 1 82772 1.20814E-5 41386 0 NA
4-62849203-G-A p.Val429Ile missense LPHN3 47 82804 5.67605E-4 41402 0 4.72081E-4
4-62849210-A-T p.Glu431Val missense LPHN3 3 82814 3.62258E-5 41407 0 NA
4-62849223-A-T p.Ser435Ser synonymous LPHN3 1 82820 1.20744E-5 41410 0 6.37024E-5
4-62849225-G-A p.Arg436His missense LPHN3 4 82822 4.82963E-5 41411 0 0.00165732
4-62849226-T-C p.Arg436Arg synonymous LPHN3 4 82822 4.82963E-5 41411 0 6.37267E-5
4-62849247-C-A p.Val443Val synonymous LPHN3 1 82830 1.20729E-5 41415 0 1.65607E-5
4-62849265-A-G p.Ala449Ala synonymous LPHN3 8 82820 9.6595E-5 41410 0 6.62471E-5
4-62849268-C-A p.Leu450Leu synonymous LPHN3 1 82816 1.2075E-5 41408 0 1.65618E-5
4-62849270-T-C p.Ile451Thr missense LPHN3 2 82812 2.41511E-5 41406 0 3.18451E-5
4-62849295-C-G p.Asp459Glu missense LPHN3 2 82762 2.41657E-5 41381 0 NA
4-62849325-A-C c.1403+4A>C splice_region LPHN3 1 82640 1.21007E-5 41320 0 8.28858E-6
4-62862074-T-C p.Met490Thr missense+splice_region LPHN3 2 81894 2.44218E-5 40947 0 1.66152E-5
4-62863901-A-T p.Ile494Phe missense LPHN3 3 81098 3.69923E-5 40549 0 4.53519E-6
4-62863903-C-A p.Ile494Ile synonymous LPHN3 1 81178 1.23186E-5 40589 0 NA
4-62863921-A-G p.Leu500Leu synonymous LPHN3 3 81514 3.68035E-5 40757 0 3.18431E-5
4-62863923-A-G p.Tyr501Cys missense LPHN3 1 81508 1.22687E-5 40754 0 NA
4-62863943-G-T p.Ala508Ser missense LPHN3 1 81550 1.22624E-5 40775 0 NA
4-62863969-T-C p.Cys516Cys synonymous LPHN3 2 81168 2.46403E-5 40584 0 1.34283E-5
4-62863971-T-C p.Leu517Pro missense LPHN3 1 81058 1.23368E-5 40529 0 NA
4-62863973-G-A p.Asp518Asn missense LPHN3 1 80964 1.23512E-5 40482 0 8.77639E-6
4-62863974-A-G p.Asp518Gly missense LPHN3 2 80958 2.47042E-5 40479 0 NA
4-62863979-A-G p.Ile520Val missense LPHN3 1 80530 1.24177E-5 40265 0 1.90463E-5
4-62894567-C-A c.3192-6C>A splice_region LPHN3 1 81254 1.23071E-5 40627 0 NA
4-62894575-A-G p.Tyr1065Cys missense+splice_region LPHN3 2 81264 2.46111E-5 40632 0 3.19142E-5
4-62894581-A-T p.Asp1067Val missense LPHN3 1 81268 1.2305E-5 40634 0 NA
4-62897154-C-T c.1563-6C>T splice_region LPHN3 1 81238 1.23095E-5 40619 0 8.35548E-6
4-62897163-A-G p.Ser522Ser synonymous LPHN3 2 81502 2.45393E-5 40751 0 6.66756E-5
4-62897185-C-G p.Leu530Val missense LPHN3 3 81764 3.6691E-5 40882 0 6.25E-4
4-62897196-A-G p.Leu533Leu synonymous LPHN3 7 81842 8.55307E-5 40921 0 5.82072E-5
4-62897197-T-C p.Leu534Leu synonymous LPHN3 3 81852 3.66515E-5 40926 0 1.89325E-4
4-62897228-A-G p.Tyr544Cys missense LPHN3 1 81820 1.2222E-5 40910 0 8.05367E-6
4-62897235-T-A p.Asn546Lys missense LPHN3 1 81810 1.22234E-5 40905 0 4.02719E-6
4-62897242-A-G p.Thr549Ala missense LPHN3 2 81822 2.44433E-5 40911 0 NA
4-62897244-A-G p.Thr549Thr synonymous LPHN3 1 81802 1.22246E-5 40901 0 NA
4-62897246-T-G p.Val550Gly missense LPHN3 1 81784 1.22273E-5 40892 0 3.19183E-5
4-62897253-G-T p.Met552Ile missense LPHN3 1 81780 1.22279E-5 40890 0 NA
4-62897256-C-G p.Ala553Ala synonymous LPHN3 58 81764 7.09359E-4 40882 0 8.93826E-4
4-62897302-A-G p.Ile569Val missense LPHN3 1 81344 1.22935E-5 40672 0 8.36148E-6
4-62897332-A-G c.1731+4A>G splice_region LPHN3 2 80602 2.48133E-5 40301 0 NA
4-62903453-G-A p.Arg579Gln missense LPHN3 2 82344 2.42884E-5 41172 0 5.03525E-4
4-62903454-A-C p.Arg579Arg synonymous LPHN3 3 82352 3.6429E-5 41176 0 NA
4-62903457-A-G p.Lys580Lys synonymous LPHN3 2 82382 2.42771E-5 41191 0 NA
4-62903462-A-T p.Tyr582Phe missense LPHN3 1 82390 1.21374E-5 41195 0 NA
4-62903477-G-A p.Arg587Gln missense LPHN3 2 82428 2.42636E-5 41214 0 1.6069E-5
4-62903489-G-T p.Cys591Phe missense LPHN3 1 82454 1.2128E-5 41227 0 NA
4-62903505-A-G p.Thr596Thr synonymous LPHN3 1 82398 1.21362E-5 41199 0 NA
4-62903516-T-A p.Ile600Asn missense LPHN3 23 82360 2.79262E-4 41180 0 4.46002E-4
4-62903516-T-C p.Ile600Thr missense LPHN3 2 82360 2.42836E-5 41180 0 3.18573E-5
4-62903517-T-C p.Ile600Ile synonymous LPHN3 1 82360 1.21418E-5 41180 0 NA
4-62903520-T-C p.Gly601Gly synonymous LPHN3 1 82324 1.21471E-5 41162 0 0.0025
4-62903522-C-T p.Ser602Leu missense LPHN3 1 82320 1.21477E-5 41160 0 NA
4-62903532-A-C p.Thr605Thr synonymous LPHN3 1 82226 1.21616E-5 41113 0 4.01845E-6
4-62903542-C-T p.Arg609* stop_gained LPHN3 1 82142 1.2174E-5 41071 0 4.01916E-6
4-62903554-C-T p.Arg613Cys missense LPHN3 2 82018 2.43849E-5 41009 0 1.20593E-5
4-62903560-T-A p.Ser615Thr missense LPHN3 3 81992 3.65889E-5 40996 0 6.37064E-5
4-62903571-A-G p.Ser618Ser synonymous LPHN3 1 81938 1.22043E-5 40969 0 NA
4-62910164-C-T c.1858-7C>T splice_region LPHN3 6 82042 7.31333E-5 41021 0 4.14224E-4
4-62910175-G-A p.Arg621Gln missense LPHN3 1 82160 1.21714E-5 41080 0 4.79115E-6
4-62910181-G-A p.Arg623His missense LPHN3 1 82236 1.21601E-5 41118 0 9.37585E-6
4-62910191-G-T p.Trp626Cys missense LPHN3 1 82292 1.21518E-5 41146 0 NA
4-62910200-G-A p.Thr629Thr synonymous LPHN3 12 82264 1.45872E-4 41132 0 0.0025
4-62910208-A-G p.Lys632Arg missense LPHN3 2 82238 2.43197E-5 41119 0 NA
4-62910209-G-A p.Lys632Lys synonymous LPHN3 1 82258 1.21569E-5 41129 0 NA
4-62910212-G-A p.Gln633Gln synonymous LPHN3 2 82254 2.43149E-5 41127 0 1.96533E-5
4-62910214-CAG-C p.Glu635fs frameshift LPHN3 1 82256 1.21572E-5 41128 0 NA
4-62910237-G-A p.Asp642Asn missense LPHN3 1 82112 1.21785E-5 41056 0 3.96259E-5
4-62910254-G-A p.Ala647Ala synonymous LPHN3 34 81950 4.14887E-4 40975 0 0.00100705
4-62929219-C-T c.3611-4C>T splice_region LPHN3 1 51476 1.94265E-5 25738 0 8.03613E-6
4-62929254-T-A p.Ala1214Ala synonymous LPHN3 1 52096 1.91953E-5 26048 0 NA
4-62929261-C-T p.Arg1217Cys missense LPHN3 2 52118 3.83745E-5 26059 0 7.52899E-6
4-62929262-G-A p.Arg1217His missense LPHN3 5 52100 9.59693E-5 26050 0 0.00135687
4-62929266-G-A p.Pro1218Pro synonymous LPHN3 1 52142 1.91784E-5 26071 0 8.15129E-5
4-62929279-A-C p.Asn1223His missense LPHN3 1 52210 1.91534E-5 26105 0 NA
4-62929289-A-G p.Asn1226Ser missense LPHN3 1 52234 1.91446E-5 26117 0 NA
4-62929298-T-C p.Leu1229Pro missense LPHN3 25 52178 4.79129E-4 26089 0 0.00171065
4-62929308-G-A p.Pro1232Pro synonymous LPHN3 45 52178 8.62432E-4 26089 0 5.10497E-4
4-62929310-C-T p.Ala1233Val missense LPHN3 1 52178 1.91652E-5 26089 0 1.05392E-4
4-62929311-G-A p.Ala1233Ala synonymous LPHN3 11 52172 2.10841E-4 26086 0 2.44618E-4
4-62929329-T-G p.Ser1239Ser synonymous LPHN3 1 52144 1.91777E-5 26072 0 NA
4-62929344-C-T p.Asn1244Asn synonymous LPHN3 2 52112 3.83789E-5 26056 0 2.29649E-5
4-62929345-G-A p.Ala1245Thr missense LPHN3 1 52084 1.91998E-5 26042 0 1.53884E-5
4-62933878-G-A c.3740-6G>A splice_region LPHN3 2 77352 2.58558E-5 38676 0 8.47486E-6
4-62933924-T-A p.Ile1260Ile synonymous LPHN3 4 77872 5.13663E-5 38936 0 6.3743E-5
4-62933925-G-T p.Ala1261Ser missense LPHN3 1 77838 1.28472E-5 38919 0 NA
4-62933928-T-C p.Tyr1262His missense LPHN3 1 77816 1.28508E-5 38908 0 8.49257E-6
4-62933939-AT-A c.3791+5delT splice_region LPHN3 30 77690 3.8615E-4 38845 0 3.74179E-4
4-62933939-A-AT c.3791+4_3791+5insT splice_region LPHN3 1 77692 1.28713E-5 38846 0 6.46729E-5
4-62935819-T-C c.1955-8T>C splice_region LPHN3 3 82416 3.64007E-5 41208 0 3.18573E-5
4-62935830-G-A p.Gly653Glu missense LPHN3 2 82728 2.41756E-5 41364 0 8.51948E-6
4-62935844-G-A p.Ala658Thr missense LPHN3 1 82926 1.20589E-5 41463 0 NA
4-62935851-A-G p.Asp660Gly missense LPHN3 1 82986 1.20502E-5 41493 0 5.03525E-4
4-62935858-T-C p.Cys1275Arg missense LPHN3 3 83002 3.61437E-5 41501 0 1.66362E-5
4-62935893-G-A p.Gly674Asp missense LPHN3 1 83076 1.20372E-5 41538 0 NA
4-62935894-C-G p.Gly674Gly synonymous LPHN3 1 83074 1.20375E-5 41537 0 3.18552E-5
4-62935899-G-C p.Ser676Thr missense LPHN3 1 83088 1.20354E-5 41544 0 NA
4-62935906-C-T p.Ser678Ser synonymous LPHN3 1 83104 1.20331E-5 41552 0 NA
4-62935915-C-T p.Ser681Ser synonymous LPHN3 82 83070 9.87119E-4 41535 0 0.00115568
4-62935923-A-G p.Tyr684Cys missense LPHN3 2 83086 2.40714E-5 41543 0 8.0262E-6
4-62935925-C-T p.Leu685Leu synonymous LPHN3 1 83092 1.20349E-5 41546 0 NA
4-62935941-A-G p.Gln690Arg missense LPHN3 1 83108 1.20325E-5 41554 0 4.01542E-6
4-62935943-A-G p.Ile691Val missense LPHN3 1 83108 1.20325E-5 41554 0 8.70186E-5
4-62935947-T-C p.Ile692Thr missense LPHN3 1 83116 1.20314E-5 41558 0 NA
4-62935952-C-G p.Arg694Gly missense LPHN3 4 83092 4.81394E-5 41546 0 4.02881E-6
4-62935952-C-T p.Arg694Cys missense LPHN3 1 83092 1.20349E-5 41546 0 3.18593E-5
4-62935953-G-A p.Arg694His missense LPHN3 1 83102 1.20334E-5 41551 0 2.82024E-5
4-62935969-C-G p.Asn699Lys missense LPHN3 4 83056 4.81603E-5 41528 0 1.13332E-5
4-62935970-G-A p.Glu700Lys missense LPHN3 2 83036 2.40859E-5 41518 0 1.13474E-5
4-62935975-C-T p.Thr701Thr synonymous LPHN3 1 83038 1.20427E-5 41519 0 0.001875
4-62935976-G-A p.Ala702Thr missense LPHN3 4 83028 4.81765E-5 41514 0 9.57549E-5
4-62935977-C-A p.Ala702Asp missense LPHN3 1 83036 1.2043E-5 41518 0 1.70656E-5
4-62936005-C-A p.Leu711Leu synonymous LPHN3 1 82872 1.20668E-5 41436 0 5.26881E-6
4-62936016-A-G p.Tyr715Cys missense LPHN3 2 82782 2.41598E-5 41391 0 2.8177E-5
4-62936017-T-C p.Tyr715Tyr synonymous LPHN3 4 82770 4.83267E-5 41385 0 4.651E-5
4-62936018-A-G p.Ile716Val missense LPHN3 1 82752 1.20843E-5 41376 0 NA
4-62936035-C-A p.Asn721Lys missense LPHN3 1 82518 1.21186E-5 41259 0 NA
4-62936040-A-G p.His723Arg missense LPHN3 1 82464 1.21265E-5 41232 0 NA
4-62936045-C-T p.Arg725Cys missense LPHN3 1 82432 1.21312E-5 41216 0 6.22138E-6
4-62936046-G-A p.Arg725His missense LPHN3 2 82426 2.42642E-5 41213 0 1.24597E-5
4-62936051-A-C p.Ser727Arg missense LPHN3 1 82416 1.21336E-5 41208 0 NA
4-62936070-T-C p.Leu733Pro missense LPHN3 2 82306 2.42996E-5 41153 0 5.50055E-4
4-62936092-C-A p.Asn740Lys missense LPHN3 239 82198 0.00290761 41099 2 0.004375
4-62936092-CC-TT p.AsnLeu740AsnPhe missense LPHN3 3 82208 3.64928E-5 41104 0 NA
4-62936143-G-A p.Ser757Ser synonymous LPHN3 13 82092 1.58359E-4 41046 0 6.25E-4
4-62936143-G-C p.Ser757Ser synonymous LPHN3 3 82094 3.65435E-5 41047 0 NA
4-62936152-C-T p.His760His synonymous LPHN3 2 82084 2.43653E-5 41042 0 4.3573E-5
4-62936152-C-G p.His760Gln missense LPHN3 8 82084 9.74611E-5 41042 1 1.27934E-5
4-62936153-G-A p.Glu761Lys missense LPHN3 1 82098 1.21806E-5 41049 0 3.19836E-5
4-62936157-A-G p.Glu762Gly missense LPHN3 1 82102 1.218E-5 41051 0 NA
4-62936170-G-A p.Leu766Leu synonymous LPHN3 3 82088 3.65461E-5 41044 0 NA
4-62936174-C-T p.Leu768Phe missense LPHN3 1 82094 1.21812E-5 41047 0 6.42599E-6
4-62936206-G-T p.Leu778Leu synonymous LPHN3 3 81924 3.66193E-5 40962 0 4.5375E-5
4-62936208-C-T p.Pro779Leu missense LPHN3 2 81938 2.44087E-5 40969 0 NA
4-62936209-C-T p.Pro779Pro synonymous LPHN3 1 81930 1.22055E-5 40965 0 6.48214E-6
4-62936210-C-T p.Pro780Ser missense LPHN3 1 81908 1.22088E-5 40954 0 4.59812E-5
4-62936228-G-A p.Glu786Lys missense LPHN3 1 81770 1.22294E-5 40885 0 0.00442478
4-62936248-T-C p.His792His synonymous LPHN3 1 81834 1.22199E-5 40917 0 NA
4-62936250-A-T p.Tyr793Phe missense LPHN3 1 81830 1.22205E-5 40915 0 NA
4-62936262-G-A p.Arg797Gln missense LPHN3 2 81774 2.44577E-5 40887 0 0.00174216
4-62936266-C-T p.Ile798Ile synonymous LPHN3 1 81792 1.22261E-5 40896 0 NA
4-62936279-A-C p.Ser803Arg missense LPHN3 2 81842 2.44373E-5 40921 0 6.43882E-6
4-62936281-T-G p.Ser803Arg missense LPHN3 2 81834 2.44397E-5 40917 0 NA
4-62936309-G-A p.Glu813Lys missense LPHN3 23 81688 2.81559E-4 40844 0 5.13268E-5
4-62936339-A-C p.Arg823Arg synonymous LPHN3 1 81580 1.22579E-5 40790 0 NA
4-62936348-C-T p.Leu826Phe missense LPHN3 5 81596 6.12775E-5 40798 0 4.63865E-5
4-62936350-C-T p.Leu826Leu synonymous LPHN3 2 81588 2.45134E-5 40794 0 6.41552E-6
4-62936363-C-A p.Pro831Thr missense LPHN3 1 81496 1.22705E-5 40748 0 NA
4-62936364-C-T p.Pro831Leu missense LPHN3 1 81490 1.22714E-5 40745 0 3.18959E-5
4-62936365-G-A p.Pro831Pro synonymous LPHN3 2 81484 2.45447E-5 40742 0 3.22356E-5
4-62936372-G-A p.Ala834Thr missense LPHN3 3 81430 3.68415E-5 40715 0 9.56511E-5
4-62936376-G-A p.Gly835Asp missense LPHN3 1 81374 1.22889E-5 40687 0 6.48694E-6
4-62936377-T-G p.Gly835Gly synonymous LPHN3 5 80998 6.17299E-5 40499 0 0.0244161
4-62936379-T-G p.Val836Gly missense LPHN3 2 81046 2.46773E-5 40523 0 0.00567369
4-62936383-C-T p.Ala837Ala synonymous LPHN3 24 81206 2.95545E-4 40603 0 4.14541E-4
4-62936384-G-A p.Ala838Thr missense LPHN3 20 81154 2.46445E-4 40577 0 2.19613E-4
4-62936384-G-T p.Ala838Ser missense LPHN3 1 81154 1.23223E-5 40577 0 NA
4-62936389-A-C p.Thr839Thr synonymous LPHN3 2 81262 2.46117E-5 40631 0 6.37592E-5
4-62936394-G-T p.Ser841Ile missense LPHN3 1 81302 1.22998E-5 40651 0 NA
4-62936401-C-G p.Thr843Thr synonymous LPHN3 1 81390 1.22865E-5 40695 0 NA
4-62936406-G-A p.Ser845Asn missense LPHN3 5 81402 6.14236E-5 40701 0 9.53289E-5
4-62936417-G-A p.Glu849Lys missense LPHN3 2 81480 2.45459E-5 40740 0 6.25E-4
4-62936424-C-T p.Pro851Leu missense LPHN3 1 81608 1.22537E-5 40804 0 NA
4-62936427-C-T p.Pro852Leu missense LPHN3 2 81608 2.45074E-5 40804 0 1.89934E-4
4-62936430-C-T p.Ala853Val missense LPHN3 2 81652 2.44942E-5 40826 0 7.69665E-5
4-62936436-G-A p.Cys855Tyr missense LPHN3 3 81704 3.67179E-5 40852 0 NA
4-62936446-C-T p.Ala858Ala synonymous LPHN3 1 81792 1.22261E-5 40896 0 6.40861E-6
4-62936450-G-A p.Asp860Asn missense LPHN3 4 81866 4.88603E-5 40933 0 1.4127E-4
4-62936451-A-G p.Asp860Gly missense LPHN3 1 81868 1.22148E-5 40934 0 NA
4-62936468-A-G p.Met866Val missense LPHN3 1 81972 1.21993E-5 40986 0 NA
4-62936488-A-T p.Arg872Ser missense LPHN3 1 82140 1.21743E-5 41070 0 NA
4-62936498-C-T p.His876Tyr missense LPHN3 1 82178 1.21687E-5 41089 0 3.18573E-5
4-62936499-A-G p.His876Arg missense LPHN3 1 82172 1.21696E-5 41086 0 6.39697E-6
4-62936506-G-A p.Leu878Leu synonymous LPHN3 6 82182 7.30087E-5 41091 0 6.25E-4
4-62936508-A-C p.His879Pro missense LPHN3 1 82200 1.21655E-5 41100 0 NA
4-62936508-A-G p.His879Arg missense LPHN3 1 82200 1.21655E-5 41100 0 3.18613E-5
4-62936517-A-C p.Tyr882Ser missense LPHN3 1 82202 1.21652E-5 41101 0 NA
4-62936544-G-T p.Gly891Val missense LPHN3 2 82230 2.4322E-5 41115 0 6.38757E-6
4-62936556-C-T p.Pro895Leu missense LPHN3 3 82202 3.64955E-5 41101 0 6.37064E-5
4-62936563-C-A p.Asn897Lys missense LPHN3 1 82208 1.21643E-5 41104 0 NA
4-62936572-G-T p.Gly900Gly synonymous LPHN3 2 82196 2.43321E-5 41098 0 1.27691E-4
4-62936576-C-T p.Pro902Ser missense LPHN3 1 82174 1.21693E-5 41087 0 1.27717E-5
4-62936582-G-A p.Glu904Lys missense LPHN3 1 82172 1.21696E-5 41086 0 1.91762E-5
4-62936594-A-T p.Lys908* stop_gained LPHN3 2 82258 2.43137E-5 41129 0 1.92081E-5
4-62936599-A-G p.Gly909Gly synonymous LPHN3 1 82222 1.21622E-5 41111 0 NA
4-62936601-C-T p.Pro910Leu missense LPHN3 184 82226 0.00223774 41113 1 0.00471728
4-62936602-G-A p.Pro910Pro synonymous LPHN3 7 82228 8.51292E-5 41114 0 9.65848E-5
4-62936603-G-A p.Ala911Thr missense LPHN3 1 82240 1.21595E-5 41120 0 NA
4-62936606-C-T p.His912Tyr missense LPHN3 2 82252 2.43155E-5 41126 0 NA
4-62936612-G-A p.Val914Ile missense LPHN3 1 82258 1.21569E-5 41129 0 NA
4-62936755-C-T c.*868C>T splice_region LPHN3 1 74724 1.33826E-5 37362 0 NA
4-62936763-CT-C c.*149delT splice_region LPHN3 295 62004 0.00475776 31002 0 0.00667696
4-62936763-C-CT c.*149dupT splice_region LPHN3 139 65224 0.00213112 32612 0 0.00463142
4-62938154-T-G c.*1528T>G splice_region LPHN3 75 41698 0.00179865 20849 1 8.92118E-4
4-62938165-T-C c.*1539T>C splice_region LPHN3 4 41548 9.62742E-5 20774 0 NA
4-62938183-A-T c.*1557A>T splice_region LPHN3 1 41136 2.43096E-5 20568 0 3.18674E-5