Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
1-82266187-C-T c.-111C>T 5_prime_UTR_premature_start_codon_gain LPHN2 1 2834 3.52858E-4 1417 0 NA
1-82266194-C-T c.-104C>T 5_prime_UTR_premature_start_codon_gain LPHN2 1 2686 3.72301E-4 1343 0 NA
1-82302562-T-G c.-100-8T>G splice_region LPHN2 1 72560 1.37817E-5 36280 0 NA
1-82302572-A-G c.-98A>G 5_prime_UTR_premature_start_codon_gain LPHN2 2 74100 2.69906E-5 37050 0 NA
1-82302677-C-T p.Ser3Phe missense LPHN2 2 82690 2.41867E-5 41345 0 2.55086E-4
1-82302692-T-A p.Met8Lys missense LPHN2 2 82736 2.41733E-5 41368 0 2.49058E-5
1-82302694-C-A p.Arg9Arg synonymous LPHN2 1 82676 1.20954E-5 41338 0 3.18796E-5
1-82302695-G-A p.Arg9Gln missense LPHN2 123 82698 0.00148734 41349 0 0.00121127
1-82302700-C-G p.Leu11Val missense LPHN2 2 82722 2.41774E-5 41361 0 1.71644E-5
1-82302705-G-T p.Trp12Cys missense LPHN2 1 82714 1.20899E-5 41357 0 8.30565E-6
1-82302711-C-A p.Ile14Ile synonymous LPHN2 1 82686 1.20939E-5 41343 0 NA
1-82302715-G-C p.Val16Leu missense LPHN2 2 82648 2.4199E-5 41324 0 8.3138E-6
1-82302747-G-A c.73+5G>A splice_region LPHN2 2 82222 2.43244E-5 41111 0 NA
1-82372735-T-C p.Val36Ala missense LPHN2 1 82752 1.20843E-5 41376 0 8.25232E-6
1-82372741-G-A p.Arg38Gln missense LPHN2 1 82800 1.20773E-5 41400 0 3.98368E-6
1-82372751-C-T p.Ser41Ser synonymous LPHN2 2 82882 2.41307E-5 41441 0 8.24457E-6
1-82372759-G-C p.Gly44Ala missense LPHN2 1 82922 1.20595E-5 41461 0 NA
1-82372783-C-T p.Pro52Leu missense LPHN2 1 83010 1.20467E-5 41505 0 NA
1-82372791-G-A p.Asp55Asn missense LPHN2 1 83060 1.20395E-5 41530 0 NA
1-82372797-A-G p.Ile57Val missense LPHN2 5 83052 6.02032E-5 41526 0 8.23968E-6
1-82372803-A-G p.Ile59Val missense LPHN2 35 83058 4.21392E-4 41529 0 6.37227E-4
1-82372811-C-T p.Ser61Ser synonymous LPHN2 9 83072 1.0834E-4 41536 0 1.23589E-4
1-82372812-G-A p.Ala62Thr missense LPHN2 1 83066 1.20386E-5 41533 0 8.239E-6
1-82372828-C-T p.Thr67Met missense LPHN2 2 83102 2.40668E-5 41551 0 3.18613E-5
1-82372829-G-A p.Thr67Thr synonymous LPHN2 2 83118 2.40622E-5 41559 0 3.9807E-6
1-82372868-G-T p.Glu80Asp missense LPHN2 2 83154 2.40518E-5 41577 0 3.18593E-5
1-82372884-C-T p.Leu86Phe missense LPHN2 1 83116 1.20314E-5 41558 0 7.96096E-6
1-82372886-C-A p.Leu86Leu synonymous LPHN2 1 83122 1.20305E-5 41561 0 3.29582E-5
1-82372890-G-A p.Asp88Asn missense LPHN2 2 83116 2.40628E-5 41558 0 7.96445E-6
1-82372898-C-T p.Phe90Phe synonymous LPHN2 1 83094 1.20346E-5 41547 0 NA
1-82372913-A-T p.Gln95His missense+splice_region LPHN2 1 82944 1.20563E-5 41472 0 NA
1-82372921-T-C c.287+6T>C splice_region LPHN2 16 82886 1.93036E-4 41443 0 6.25E-4
1-82372922-A-G c.287+7A>G splice_region LPHN2 1 82888 1.20645E-5 41444 0 NA
1-82402420-A-G p.Asn99Ser missense LPHN2 1 81636 1.22495E-5 40818 0 1.21727E-5
1-82402430-G-T p.Gln102His missense LPHN2 1 82518 1.21186E-5 41259 0 NA
1-82402439-A-G p.Val105Val synonymous LPHN2 2 82722 2.41774E-5 41361 0 5.03525E-4
1-82402445-T-A p.Thr107Thr synonymous LPHN2 19 82726 2.29674E-4 41363 0 1.83415E-4
1-82402481-A-G p.Thr119Thr synonymous LPHN2 1 82584 1.21089E-5 41292 0 8.2462E-6
1-82407723-C-CA p.Val137fs frameshift LPHN2 1 52038 1.92167E-5 26019 0 NA
1-82407736-A-G c.409+7A>G splice_region LPHN2 1 52096 1.91953E-5 26048 0 NA
1-82408639-TCTGTAA-T c.398-13_398-8delCTGTAA splice_region LPHN2 1 82128 1.21761E-5 41064 0 1.68532E-5
1-82408672-C-G p.Thr139Thr synonymous LPHN2 1 82302 1.21504E-5 41151 0 NA
1-82408700-A-G p.Ile149Val missense LPHN2 1 82508 1.212E-5 41254 0 3.18796E-5
1-82408707-A-C p.Glu151Ala missense LPHN2 2 82516 2.42377E-5 41258 0 9.19375E-5
1-82408715-C-A p.Gln154Lys missense LPHN2 2 82492 2.42448E-5 41246 0 NA
1-82408722-C-T p.Ala156Val missense LPHN2 6 82452 7.27696E-5 41226 0 9.57182E-5
1-82408723-G-A p.Ala156Ala synonymous LPHN2 2 82428 2.42636E-5 41214 0 8.29325E-6
1-82408736-A-G p.Lys161Glu missense LPHN2 1 82352 1.2143E-5 41176 0 3.99422E-6
1-82408745-C-T p.Leu164Phe missense LPHN2 1 82308 1.21495E-5 41154 0 NA
1-82408751-G-T p.Ala166Ser missense LPHN2 1 82270 1.21551E-5 41135 0 8.28075E-6
1-82408752-C-G p.Ala166Gly missense LPHN2 1 82272 1.21548E-5 41136 0 3.99549E-6
1-82408755-C-G p.Ala167Gly missense LPHN2 1 82238 1.21598E-5 41119 0 NA
1-82408806-T-C p.Ile184Thr missense LPHN2 1 81954 1.2202E-5 40977 0 NA
1-82408820-T-G p.Leu189Val missense LPHN2 1 81928 1.22058E-5 40964 0 3.99706E-6
1-82408832-C-CA p.Asn194fs frameshift LPHN2 1 81918 1.22073E-5 40959 0 NA
1-82408836-A-G p.Asn194Ser missense LPHN2 1 81956 1.22017E-5 40978 0 3.99664E-6
1-82408840-TC-CT p.SerArg195SerCys missense LPHN2 4 81932 4.8821E-5 40966 0 NA
1-82408841-C-T p.Arg196Cys missense LPHN2 1 81946 1.22032E-5 40973 0 7.99463E-6
1-82408842-G-A p.Arg196His missense LPHN2 1 81934 1.22049E-5 40967 0 8.26706E-6
1-82408855-A-G p.Thr200Thr synonymous LPHN2 7 81986 8.53804E-5 40993 0 1.99789E-5
1-82408856-T-C p.Tyr201His missense LPHN2 2 81984 2.4395E-5 40992 0 8.26624E-6
1-82408876-A-G p.Val207Val synonymous LPHN2 1 81968 1.21999E-5 40984 0 2.39808E-5
1-82408905-G-A p.Gly217Asp missense LPHN2 2 82212 2.43273E-5 41106 0 NA
1-82408934-A-C p.Arg227Arg synonymous LPHN2 1 82162 1.21711E-5 41081 0 3.18715E-5
1-82408963-T-C p.Thr236Thr synonymous LPHN2 1 82108 1.21791E-5 41054 0 NA
1-82408966-A-C p.Arg237Ser missense LPHN2 1 82122 1.2177E-5 41061 0 9.56206E-5
1-82408977-G-A p.Gly241Asp missense LPHN2 1 81984 1.21975E-5 40992 0 NA
1-82408981-G-A p.Glu242Glu synonymous LPHN2 1 81990 1.21966E-5 40995 0 4.9545E-5
1-82409009-G-A p.Asp252Asn missense LPHN2 1 81756 1.22315E-5 40878 0 NA
1-82409047-C-T p.Ile264Ile synonymous LPHN2 1 81576 1.22585E-5 40788 0 8.25028E-6
1-82409060-G-GATGAAAATGGTTTATGGGTC p.Ile276fs frameshift LPHN2 3 81554 3.67854E-5 40777 0 NA
1-82409067-A-G p.Asn271Ser missense LPHN2 2 81528 2.45314E-5 40764 0 NA
1-82409071-T-A p.Gly272Gly synonymous LPHN2 1 81512 1.22681E-5 40756 0 8.24892E-6
1-82409081-A-G p.Ile276Val missense LPHN2 1 81544 1.22633E-5 40772 0 NA
1-82409086-C-T p.Tyr277Tyr synonymous LPHN2 2 81526 2.45321E-5 40763 0 3.59879E-5
1-82409097-A-G p.Gln281Arg missense LPHN2 2 81584 2.45146E-5 40792 0 3.99754E-6
1-82409098-G-A p.Gln281Gln synonymous LPHN2 1 81574 1.22588E-5 40787 0 7.99687E-6
1-82409107-A-G p.Gly284Gly synonymous LPHN2 1 81652 1.22471E-5 40826 0 7.59435E-5
1-82409133-C-G p.Pro293Arg missense LPHN2 2 81916 2.44153E-5 40958 0 NA
1-82409140-T-G p.Thr295Thr synonymous LPHN2 1 81998 1.21954E-5 40999 0 NA
1-82409157-C-T p.Thr301Met missense LPHN2 6 82208 7.29856E-5 41104 0 3.18715E-5
1-82409158-G-A p.Thr301Thr synonymous LPHN2 2 82248 2.43167E-5 41124 0 NA
1-82409163-A-T p.Glu303Val missense LPHN2 1 82296 1.21513E-5 41148 0 NA
1-82409173-C-T p.Tyr306Tyr synonymous LPHN2 3 82448 3.63866E-5 41224 0 1.19673E-5
1-82409174-G-A p.Asp307Asn missense LPHN2 12 82464 1.45518E-4 41232 0 2.54956E-4
1-82409185-C-T p.Ala310Ala synonymous LPHN2 5 82560 6.0562E-5 41280 0 3.98788E-5
1-82409186-G-T p.Ala311Ser missense LPHN2 1 82588 1.21083E-5 41294 0 3.98762E-6
1-82409188-A-C p.Ala311Ala synonymous LPHN2 1 82626 1.21027E-5 41313 0 5.03525E-4
1-82409201-A-T p.Met316Leu missense LPHN2 1 82756 1.20837E-5 41378 0 NA
1-82409212-A-G p.Gly319Gly synonymous LPHN2 1 82824 1.20738E-5 41412 0 8.2447E-6
1-82409224-G-A p.Val323Val synonymous LPHN2 2 82900 2.41255E-5 41450 0 NA
1-82409245-C-A p.Asp330Glu missense LPHN2 1 82912 1.2061E-5 41456 0 NA
1-82409260-A-G p.Thr335Thr synonymous LPHN2 2 82940 2.41138E-5 41470 0 3.18857E-5
1-82409266-G-T p.Lys337Asn missense LPHN2 2 82924 2.41185E-5 41462 0 NA
1-82409269-C-T p.Asn338Asn synonymous LPHN2 61 82912 7.3572E-4 41456 0 5.43845E-4
1-82409284-T-G p.Ile343Met missense LPHN2 1 82846 1.20706E-5 41423 0 8.23968E-6
1-82409289-A-G p.Asn345Ser missense LPHN2 1 82798 1.20776E-5 41399 0 3.98467E-6
1-82409296-A-G p.Arg347Arg synonymous LPHN2 2 82772 2.41628E-5 41386 0 1.64785E-5
1-82409300-A-T p.Asn349Tyr missense LPHN2 3 82738 3.6259E-5 41369 0 NA
1-82409301-A-G p.Asn349Ser missense LPHN2 3 82722 3.6266E-5 41361 0 6.25E-4
1-82409303-C-T p.Arg350* stop_gained LPHN2 1 82704 1.20913E-5 41352 0 3.98584E-6
1-82409304-G-A p.Arg350Gln missense LPHN2 5 82668 6.04829E-5 41334 0 9.5645E-5
1-82409337-A-G p.Gln361Arg missense LPHN2 119 82606 0.00144057 41303 0 0.00956697
1-82409338-G-A p.Gln361Gln synonymous LPHN2 7 82618 8.47273E-5 41309 0 3.18883E-5
1-82409338-G-T p.Gln361His missense LPHN2 1 82618 1.21039E-5 41309 0 NA
1-82409341-T-C p.Tyr362Tyr synonymous LPHN2 1 82636 1.21013E-5 41318 0 NA
1-82409352-C-T p.Ala366Val missense LPHN2 11 82648 1.33095E-4 41324 0 0.00124338
1-82409383-A-G p.Gln376Gln synonymous LPHN2 1 82806 1.20764E-5 41403 0 NA
1-82409389-C-T p.Tyr378Tyr synonymous LPHN2 4 82858 4.82754E-5 41429 0 3.18613E-5
1-82409415-G-A p.Arg387Gln missense LPHN2 1 82880 1.20656E-5 41440 0 3.98699E-6
1-82409416-A-T p.Arg387Arg synonymous LPHN2 4 82878 4.82637E-5 41439 0 9.56023E-5
1-82409437-A-G p.Pro394Pro synonymous LPHN2 2 82798 2.41552E-5 41399 0 NA
1-82409447-G-A p.Ala398Thr missense LPHN2 2 82722 2.41774E-5 41361 0 1.17127E-4
1-82409449-C-T p.Ala398Ala synonymous LPHN2 1 82738 1.20863E-5 41369 0 NA
1-82409452-A-C p.Gln399His missense+splice_region LPHN2 1 82708 1.20907E-5 41354 0 3.18715E-5
1-82409458-G-A c.1198+5G>A splice_region LPHN2 1 82638 1.2101E-5 41319 0 3.23146E-5
1-82409459-C-T c.1198+6C>T splice_region LPHN2 1 82610 1.21051E-5 41305 0 3.18918E-5
1-82409460-G-A c.1198+7G>A splice_region LPHN2 12 82584 1.45307E-4 41292 0 1.01543E-4
1-82415869-A-G c.1199-4A>G splice_region LPHN2 15 82490 1.8184E-4 41245 0 1.91424E-4
1-82415887-G-GAAGAAGTTAT p.Val405fs frameshift LPHN2 1 82602 1.21062E-5 41301 0 NA
1-82415893-A-G p.Ile407Val missense LPHN2 3 82610 3.63152E-5 41305 0 1.59546E-5
1-82415911-C-G p.Leu413Val missense LPHN2 3 82604 3.63179E-5 41302 0 3.18532E-5
1-82415921-C-T p.Thr416Ile missense LPHN2 2 82616 2.42084E-5 41308 0 NA
1-82415923-A-G p.Ile417Val missense LPHN2 5 82646 6.0499E-5 41323 0 0.00151057
1-82415925-A-G p.Ile417Met missense LPHN2 1 82634 1.21016E-5 41317 0 NA
1-82415930-C-T p.Ser419Leu missense LPHN2 4 82628 4.84097E-5 41314 0 9.55536E-5
1-82415935-A-G p.Thr421Ala missense LPHN2 1 82662 1.20975E-5 41331 0 NA
1-82415942-C-T p.Thr423Ile missense LPHN2 3 82700 3.62757E-5 41350 0 6.37064E-5
1-82415944-A-G p.Thr424Ala missense LPHN2 2 82718 2.41785E-5 41359 0 8.25627E-6
1-82415957-G-A p.Gly428Asp missense LPHN2 1 82780 1.20802E-5 41390 0 NA
1-82415957-G-C p.Gly428Ala missense LPHN2 2 82780 2.41604E-5 41390 0 NA
1-82415960-C-T p.Pro429Leu missense LPHN2 1 82814 1.20753E-5 41407 0 3.18593E-5
1-82415982-A-T p.Gly436Gly synonymous LPHN2 1633 82844 0.0197117 41422 28 0.0217259
1-82415993-G-C p.Gly440Ala missense LPHN2 3 82956 3.61638E-5 41478 0 1.19503E-5
1-82415996-G-T p.Ser441Ile missense LPHN2 2 82962 2.41074E-5 41481 0 3.98295E-6
1-82416004-A-G p.Thr444Ala missense LPHN2 2 82982 2.41016E-5 41491 0 3.18512E-5
1-82416015-T-A p.Pro447Pro synonymous LPHN2 3 82982 3.61524E-5 41491 0 3.18654E-5
1-82416025-T-C p.Ser451Pro missense LPHN2 2 82984 2.4101E-5 41492 0 NA
1-82416028-A-G p.Thr452Ala missense LPHN2 5 82996 6.02439E-5 41498 0 3.18492E-5
1-82416040-C-T p.Pro456Ser missense LPHN2 1131 82972 0.0136311 41486 18 0.0141105
1-82416046-A-G p.Ile458Val missense LPHN2 19 82992 2.28938E-4 41496 0 7.26612E-4
1-82416054-T-A p.Asn460Lys missense LPHN2 1 82992 1.20494E-5 41496 0 8.25791E-6
1-82416059-T-C p.Phe462Ser missense LPHN2 2 82994 2.40981E-5 41497 0 3.30316E-5
1-82416060-TC-T p.Leu464fs frameshift LPHN2 1 82990 1.20496E-5 41495 0 NA
1-82416061-C-G p.Pro463Ala missense LPHN2 1 82992 1.20494E-5 41496 0 NA
1-82416070-G-A c.1211-1G>A splice_acceptor LPHN2 1 83028 1.20441E-5 41514 0 NA
1-82416078-C-G p.Phe468Leu missense LPHN2 1 83018 1.20456E-5 41509 0 3.18471E-5
1-82416092-A-G p.Asp473Gly missense LPHN2 1 83006 1.20473E-5 41503 0 3.98356E-6
1-82416098-A-C p.Lys475Thr missense LPHN2 5 83014 6.02308E-5 41507 0 3.98486E-6
1-82416130-A-G p.Met486Val missense LPHN2 4 83044 4.81672E-5 41522 0 3.19203E-5
1-82416134-T-C p.Met487Thr missense LPHN2 1 83068 1.20383E-5 41534 0 3.99154E-6
1-82416143-G-A p.Arg490Gln missense LPHN2 2 83016 2.40917E-5 41508 0 8.27116E-6
1-82416144-A-G p.Arg490Arg synonymous LPHN2 2 83018 2.40912E-5 41509 0 3.99712E-6
1-82416146-C-T p.Pro491Leu missense LPHN2 1 83020 1.20453E-5 41510 0 1.19927E-5
1-82416151-C-T p.Pro493Ser missense LPHN2 1 82994 1.20491E-5 41497 0 NA
1-82416170-T-A c.1492+4T>A splice_region LPHN2 1 82844 1.20709E-5 41422 0 NA
1-82416698-G-T c.1493-4G>T splice_region LPHN2 4 82554 4.84531E-5 41277 0 6.37186E-5
1-82416709-C-T p.Ala500Ala synonymous LPHN2 4 82606 4.84226E-5 41303 0 1.1962E-5
1-82416712-A-G p.Ser501Ser synonymous LPHN2 10 82620 1.21036E-4 41310 0 6.77669E-5
1-82416725-A-T p.Ile506Phe missense LPHN2 1 82692 1.20931E-5 41346 0 3.18532E-5
1-82416728-T-C p.Ser507Pro missense LPHN2 2 82700 2.41838E-5 41350 0 3.18512E-5
1-82416732-C-T p.Thr508Ile missense LPHN2 1 82718 1.20893E-5 41359 0 NA
1-82416751-G-A p.Lys514Lys synonymous LPHN2 5 82796 6.03894E-5 41398 0 9.55779E-5
1-82416757-C-T p.Pro516Pro synonymous LPHN2 8 82806 9.66114E-5 41403 0 4.12072E-5
1-82416758-G-A p.Asp517Asn missense LPHN2 1 82792 1.20785E-5 41396 0 3.18654E-5
1-82416794-C-A p.Leu529Met missense LPHN2 6 82782 7.24795E-5 41391 0 1.99407E-5
1-82416797-G-T p.Ala530Ser missense LPHN2 4 82766 4.8329E-5 41383 0 1.91496E-4
1-82417637-T-A c.1597-4T>A splice_region LPHN2 2 82764 2.41651E-5 41382 0 4.28196E-6
1-82417649-C-T p.Ser535Ser synonymous LPHN2 11 82912 1.32671E-4 41456 1 0.00403226
1-82417650-G-A p.Gly536Arg missense LPHN2 5 82936 6.02874E-5 41468 0 1.64693E-5
1-82417654-A-C p.Glu537Ala missense LPHN2 1 82974 1.2052E-5 41487 0 1.23045E-5
1-82417671-G-A p.Ala543Thr missense LPHN2 6 83070 7.22282E-5 41535 0 6.6107E-5
1-82417673-C-T p.Ala543Ala synonymous LPHN2 2 83088 2.40709E-5 41544 0 6.36943E-5
1-82417675-A-G p.Asn544Ser missense LPHN2 6 83100 7.22022E-5 41550 0 8.25887E-6
1-82417676-T-C p.Asn544Asn synonymous LPHN2 1 83090 1.20351E-5 41545 0 NA
1-82417696-A-G p.Lys551Arg missense LPHN2 447 83150 0.00537583 41575 4 0.00513299
1-82417698-G-T p.Gly552Trp missense LPHN2 1 83168 1.20239E-5 41584 0 3.98454E-6
1-82417730-A-G p.Ser562Ser synonymous LPHN2 1 83158 1.20253E-5 41579 0 NA
1-82417752-G-C p.Val570Leu missense LPHN2 1 83162 1.20247E-5 41581 0 NA
1-82417763-T-G p.Leu573Leu synonymous LPHN2 4 83158 4.81012E-5 41579 0 9.96119E-5
1-82417766-T-C p.Asp574Asp synonymous LPHN2 14 83158 1.68354E-4 41579 0 9.24886E-4
1-82417769-A-C p.Ala575Ala synonymous LPHN2 1 83156 1.20256E-5 41578 0 8.25709E-6
1-82417773-C-T p.Leu577Leu synonymous LPHN2 49 83162 5.89211E-4 41581 0 0.00554435
1-82417792-G-A p.Ser583Asn missense LPHN2 3 83174 3.6069E-5 41587 0 3.3123E-5
1-82417802-T-C p.Asp586Asp synonymous LPHN2 1 83182 1.20218E-5 41591 0 1.60005E-5
1-82417820-T-C p.Tyr592Tyr synonymous LPHN2 3 83110 3.60967E-5 41555 0 1.27429E-4
1-82417825-A-C p.Lys594Thr missense+splice_region LPHN2 2 83080 2.40732E-5 41540 0 8.54073E-6
1-82417834-G-A c.1782+8G>A splice_region LPHN2 1 82796 1.20779E-5 41398 0 4.19688E-6
1-82418684-A-T p.Glu599Val missense LPHN2 1 76514 1.30695E-5 38257 0 NA
1-82418702-A-G p.Tyr605Cys missense LPHN2 3 76510 3.92106E-5 38255 0 NA
1-82418703-C-T p.Tyr605Tyr synonymous LPHN2 2 76494 2.61458E-5 38247 0 NA
1-82418716-C-A c.1821+7C>A splice_region LPHN2 1 76546 1.3064E-5 38273 0 3.73574E-5
1-82421557-A-C c.1822-4A>C splice_region LPHN2 1 81898 1.22103E-5 40949 0 9.47858E-6
1-82421578-G-A p.Val613Val synonymous LPHN2 1 82460 1.21271E-5 41230 0 NA
1-82421581-C-T p.Asp614Asp synonymous LPHN2 1 82492 1.21224E-5 41246 0 NA
1-82421596-C-T p.Pro619Pro synonymous LPHN2 81824 82074 0.996954 41037 40790 1.0
1-82421606-G-A p.Glu623Lys missense LPHN2 3 82786 3.6238E-5 41393 0 NA
1-82421608-A-G p.Glu623Glu synonymous LPHN2 2 82846 2.41412E-5 41423 0 2.47508E-4
1-82421617-A-G p.Lys626Lys synonymous LPHN2 9 82894 1.08572E-4 41447 0 1.31994E-4
1-82421644-T-C p.His635His synonymous LPHN2 1 82996 1.20488E-5 41498 0 NA
1-82421662-C-T p.Leu641Leu synonymous LPHN2 1 82948 1.20557E-5 41474 0 1.61106E-5
1-82421662-C-G p.Leu641Leu synonymous LPHN2 1 82948 1.20557E-5 41474 0 8.05529E-6
1-82421668-A-G p.Thr643Thr synonymous LPHN2 3 82944 3.6169E-5 41472 0 8.25205E-6
1-82421717-A-G p.Arg660Gly missense LPHN2 1 82908 1.20616E-5 41454 0 4.13562E-6
1-82421719-G-T p.Arg660Ser missense LPHN2 1 82876 1.20662E-5 41438 0 NA
1-82421728-G-A p.Met663Ile missense LPHN2 1 82686 1.20939E-5 41343 0 8.51731E-6
1-82421737-A-T p.Glu666Asp missense LPHN2 1 82630 1.21021E-5 41315 0 NA
1-82421742-T-C p.Ile668Thr missense+splice_region LPHN2 8 82530 9.69344E-5 41265 0 5.03525E-4
1-82431746-G-A p.Leu670Leu synonymous LPHN2 1 83164 1.20244E-5 41582 0 7.96229E-6
1-82431754-C-T p.Ala673Val missense LPHN2 1 83148 1.20267E-5 41574 0 3.18532E-5
1-82431755-C-T p.Ala673Ala synonymous LPHN2 3 83154 3.60776E-5 41577 0 6.37267E-5
1-82431756-G-T p.Val674Leu missense LPHN2 35 83146 4.20946E-4 41573 0 5.44043E-4
1-82431756-G-A p.Val674Ile missense LPHN2 1 83146 1.2027E-5 41573 0 1.19389E-5
1-82431770-A-G p.Glu678Glu synonymous LPHN2 1 83150 1.20265E-5 41575 0 6.25E-4
1-82431788-T-C p.Phe684Phe synonymous LPHN2 1 83156 1.20256E-5 41578 0 8.23927E-6
1-82431801-G-A p.Gly689Ser missense LPHN2 4 83114 4.81267E-5 41557 0 5.03525E-4
1-82431803-C-T p.Gly689Gly synonymous LPHN2 2 83118 2.40622E-5 41559 0 8.23968E-6
1-82431814-C-T p.Ala693Val missense LPHN2 1 83072 1.20378E-5 41536 0 NA
1-82431830-A-G p.Gln698Gln synonymous LPHN2 1 83016 1.20459E-5 41508 0 3.18492E-5
1-82431836-C-G p.Ser700Ser synonymous LPHN2 1 82988 1.20499E-5 41494 0 6.37389E-5
1-82431837-G-A p.Ala701Thr missense LPHN2 5 82976 6.02584E-5 41488 0 3.18674E-5
1-82431838-C-T p.Ala701Val missense LPHN2 12 82972 1.44627E-4 41486 0 3.2175E-4
1-82431853-A-G p.Gln706Arg missense LPHN2 2 82888 2.41289E-5 41444 0 3.18512E-5
1-82432098-G-A p.Lys714Lys synonymous LPHN2 1 82790 1.20788E-5 41395 0 3.98292E-6
1-82432102-G-T p.Val716Leu missense LPHN2 1 82814 1.20753E-5 41407 0 NA
1-82432104-G-A p.Val716Val synonymous LPHN2 2 82828 2.41464E-5 41414 0 NA
1-82432108-A-G p.Ile718Val missense LPHN2 1 82850 1.207E-5 41425 0 3.18492E-5
1-82432118-G-A p.Arg721Gln missense LPHN2 2 82890 2.41284E-5 41445 0 1.65202E-5
1-82432128-A-T p.Gly724Gly synonymous LPHN2 1 82952 1.20552E-5 41476 0 NA
1-82432131-G-A p.Gln725Gln synonymous LPHN2 50 82948 6.02787E-4 41474 1 3.26368E-4
1-82432153-A-G p.Thr733Ala missense LPHN2 1 83000 1.20482E-5 41500 0 3.97931E-6
1-82432165-G-A p.Gly737Ser missense LPHN2 2 83006 2.40946E-5 41503 0 NA
1-82432167-T-C p.Gly737Gly synonymous LPHN2 1 83020 1.20453E-5 41510 0 NA
1-82432183-C-T p.Arg743Cys missense LPHN2 3 83064 3.61167E-5 41532 0 1.64807E-5
1-82432184-G-T p.Arg743Leu missense LPHN2 170 83072 0.00204642 41536 2 0.00553877
1-82432184-G-A p.Arg743His missense LPHN2 7 83078 8.42582E-5 41539 0 2.47198E-5
1-82432212-C-T p.His752His synonymous LPHN2 1 83170 1.20236E-5 41585 0 3.18471E-5
1-82432213-G-A p.Val753Ile missense LPHN2 1 83172 1.20233E-5 41586 0 NA
1-82432216-A-G p.Ile754Val missense LPHN2 6 83188 7.21258E-5 41594 0 NA
1-82432221-A-G p.Ser755Ser synonymous LPHN2 65 83202 7.81231E-4 41601 0 8.73132E-4
1-82432239-G-A p.Glu761Glu synonymous LPHN2 37 83214 4.44637E-4 41607 0 6.37227E-5
1-82432242-C-T p.Ser762Ser synonymous LPHN2 116 83220 0.0013939 41610 0 0.00137021
1-82432247-G-A p.Arg764Gln missense LPHN2 6 83214 7.21032E-5 41607 0 1.27445E-4
1-82432254-C-T p.Tyr766Tyr synonymous LPHN2 3 83210 3.60534E-5 41605 0 6.37105E-5
1-82432269-G-T p.Val771Val synonymous LPHN2 1 83204 1.20187E-5 41602 0 3.18431E-5
1-82432288-A-T p.Ile778Phe missense LPHN2 1 83158 1.20253E-5 41579 0 NA
1-82432292-A-G p.Asp779Gly missense+splice_region LPHN2 1 83154 1.20259E-5 41577 0 NA
1-82433707-C-T c.2338-3C>T splice_region LPHN2 2 83126 2.40599E-5 41563 0 NA
1-82433707-C-A c.2338-3C>A splice_region LPHN2 1 83126 1.20299E-5 41563 0 NA
1-82433728-G-A p.Ala786Thr missense LPHN2 4 83150 4.81058E-5 41575 0 NA
1-82433730-A-G p.Ala786Ala synonymous LPHN2 3 83164 3.60733E-5 41582 0 7.41974E-5
1-82433736-C-T p.Cys788Cys synonymous LPHN2 1 83172 1.20233E-5 41586 0 2.4726E-5
1-82433751-C-T p.Tyr793Tyr synonymous LPHN2 3 83180 3.60664E-5 41590 0 3.1837E-5
1-82433801-T-C p.Val810Ala missense LPHN2 1 83182 1.20218E-5 41591 0 1.35756E-4
1-82433803-G-T p.Asp811Tyr missense LPHN2 5 83176 6.01135E-5 41588 0 3.9939E-6
1-82433817-T-C p.Thr815Thr synonymous LPHN2 1 83164 1.20244E-5 41582 0 NA
1-82433819-G-A p.Arg816Gln missense LPHN2 22 83156 2.64563E-4 41578 0 4.03737E-4
1-82433819-G-GAACAAC p.Thr818_Cys819insThrThr disruptive_inframe_insertion LPHN2 3 83156 3.60768E-5 41578 0 8.23954E-6
1-82433824-A-G p.Thr818Ala missense LPHN2 1 83146 1.2027E-5 41573 0 NA
1-82433825-C-T p.Thr818Met missense LPHN2 3 83146 3.60811E-5 41573 0 9.55353E-5
1-82433826-G-A p.Thr818Thr synonymous LPHN2 1 83138 1.20282E-5 41569 0 1.73042E-4
1-82433840-A-T p.His823Leu missense LPHN2 1 83118 1.20311E-5 41559 0 NA
1-82433862-C-T p.Leu830Leu synonymous LPHN2 1 83008 1.2047E-5 41504 0 NA
1-82433863-A-G p.Met831Val missense LPHN2 1 83002 1.20479E-5 41501 0 NA
1-82433879-T-C p.Ile836Thr missense LPHN2 1 82866 1.20677E-5 41433 0 NA
1-82434868-G-T p.Asp840Tyr missense LPHN2 2 83240 2.40269E-5 41620 0 7.96407E-6
1-82434873-C-T p.Gly841Gly synonymous LPHN2 4 83244 4.80515E-5 41622 0 3.98206E-5
1-82434874-G-A p.Val842Ile missense LPHN2 33 83250 3.96396E-4 41625 0 8.92061E-4
1-82434893-C-G p.Thr848Arg missense LPHN2 2 83298 2.40102E-5 41649 0 NA
1-82434893-C-T p.Thr848Ile missense LPHN2 5 83298 6.00254E-5 41649 0 1.19358E-5
1-82434901-A-T p.Thr851Ser missense LPHN2 2 83296 2.40108E-5 41648 0 3.29516E-5
1-82434902-C-A p.Thr851Asn missense LPHN2 1 83292 1.2006E-5 41646 0 8.23818E-6
1-82434903-C-A p.Thr851Thr synonymous LPHN2 1 83300 1.20048E-5 41650 0 2.7845E-5
1-82434903-C-G p.Thr851Thr synonymous LPHN2 1 83300 1.20048E-5 41650 0 3.97785E-6
1-82434925-C-T p.Leu859Phe missense LPHN2 1 83314 1.20028E-5 41657 0 8.2371E-6
1-82434944-G-A p.Cys865Tyr missense LPHN2 1 83314 1.20028E-5 41657 0 3.18532E-5
1-82434945-C-T p.Cys865Cys synonymous LPHN2 2 83300 2.40096E-5 41650 0 4.37536E-5
1-82434946-A-G p.Ile866Val missense LPHN2 2 83306 2.40079E-5 41653 0 3.97769E-6
1-82434946-A-T p.Ile866Phe missense LPHN2 1 83306 1.20039E-5 41653 0 NA
1-82434953-C-G p.Thr868Ser missense LPHN2 1 83310 1.20034E-5 41655 0 NA
1-82434968-G-A p.Arg873His missense LPHN2 1 83284 1.20071E-5 41642 0 1.27421E-4
1-82434980-G-A p.Ser877Asn missense LPHN2 1 83268 1.20094E-5 41634 0 8.23683E-6
1-82434986-G-A p.Arg879Gln missense LPHN2 2 83258 2.40217E-5 41629 0 9.55597E-5
1-82434994-A-G p.Ile882Val missense LPHN2 1 83262 1.20103E-5 41631 0 NA
1-82434996-T-A p.Ile882Ile synonymous LPHN2 1 83264 1.201E-5 41632 0 3.97867E-6
1-82434999-C-G p.His883Gln missense LPHN2 3 83260 3.60317E-5 41630 0 2.38739E-5
1-82435024-A-G p.Ile892Val missense LPHN2 1 83232 1.20146E-5 41616 0 NA
1-82435036-A-G p.Ile896Val missense LPHN2 1 83184 1.20215E-5 41592 0 8.24253E-6
1-82435043-T-C p.Leu898Pro missense LPHN2 1 83174 1.2023E-5 41587 0 3.18408E-5
1-82435044-A-G p.Leu898Leu synonymous LPHN2 1 83170 1.20236E-5 41585 0 8.2447E-6
1-82435051-A-G p.Ile901Val missense LPHN2 1 83136 1.20285E-5 41568 0 3.18492E-5
1-82435068-T-C p.Tyr906Tyr synonymous LPHN2 3 83088 3.61063E-5 41544 0 6.36821E-5
1-82435070-C-T p.Ala907Val missense+splice_region LPHN2 1 83078 1.20369E-5 41539 0 0.00100705
1-82435071-G-A p.Ala907Ala splice_region+synonymous LPHN2 47 83070 5.65788E-4 41535 0 4.50486E-4
1-82435079-C-T c.2721+8C>T splice_region LPHN2 14 83018 1.68638E-4 41509 0 0.00108164
1-82435993-C-T c.2722-5C>T splice_region LPHN2 26 83004 3.13238E-4 41502 0 8.60585E-4
1-82435993-C-A c.2722-5C>A splice_region LPHN2 4 83008 4.81881E-5 41504 0 NA
1-82435994-G-A c.2722-4G>A splice_region LPHN2 4 83018 4.81823E-5 41509 0 1.91424E-4
1-82436000-T-G p.Ile908Met missense+splice_region LPHN2 1 83138 1.20282E-5 41569 0 3.18492E-5
1-82436011-T-C p.Ile912Thr missense LPHN2 7 83174 8.41609E-5 41587 0 3.18593E-5
1-82436012-A-G p.Ile912Met missense LPHN2 1 83180 1.20221E-5 41590 0 3.18735E-5
1-82436030-C-G p.His918Gln missense LPHN2 1 83226 1.20155E-5 41613 0 8.3167E-6
1-82436046-G-A p.Ala924Thr missense LPHN2 2 83220 2.40327E-5 41610 0 4.2676E-6
1-82436062-G-T p.Cys929Phe missense LPHN2 3 83232 3.60438E-5 41616 0 NA
1-82436072-T-G p.Gly932Gly synonymous LPHN2 1 83212 1.20175E-5 41606 0 3.18573E-5
1-82436073-G-A p.Val933Met missense LPHN2 1 83206 1.20184E-5 41603 0 NA
1-82436081-C-G p.Leu935Leu synonymous LPHN2 2 83234 2.40286E-5 41617 0 NA
1-82436087-A-G p.Leu937Leu synonymous LPHN2 1 83198 1.20195E-5 41599 0 NA
1-82436139-G-A p.Val955Ile missense LPHN2 2 83158 2.40506E-5 41579 0 1.73208E-5
1-82436150-C-T p.Tyr958Tyr synonymous LPHN2 1 83148 1.20267E-5 41574 0 3.18613E-5
1-82436169-G-A p.Val965Ile missense LPHN2 2 83104 2.40662E-5 41552 0 3.64804E-5
1-82436204-T-C p.Tyr976Tyr synonymous LPHN2 5 82914 6.03034E-5 41457 0 1.27421E-4
1-82436214-A-G p.Lys980Glu missense LPHN2 1 82746 1.20852E-5 41373 0 8.40082E-6
1-82436217-G-A p.Ala981Thr missense+splice_region LPHN2 3 82676 3.62862E-5 41338 0 1.68002E-5
1-82436218-C-T p.Ala981Val missense+splice_region LPHN2 7 82638 8.47068E-5 41319 0 4.51334E-5
1-82437539-C-T p.Cys982Cys synonymous LPHN2 17 82414 2.06276E-4 41207 0 6.37389E-4
1-82437547-A-G p.His985Arg missense LPHN2 3 82508 3.63601E-5 41254 0 6.37146E-5
1-82437553-A-G p.Asp987Gly missense LPHN2 1 82578 1.21098E-5 41289 0 NA
1-82437577-T-C p.Ile995Thr missense LPHN2 2 82626 2.42055E-5 41313 0 3.35267E-5
1-82437580-G-T p.Gly996Val missense LPHN2 2 82618 2.42078E-5 41309 0 8.38757E-6
1-82437580-G-C p.Gly996Ala missense LPHN2 1 82618 1.21039E-5 41309 0 9.56145E-5
1-82437589-C-A p.Thr999Asn missense LPHN2 1 82598 1.21068E-5 41299 0 8.41708E-6
1-82445550-C-T c.3010-3C>T splice_region LPHN2 1 81206 1.23144E-5 40603 0 NA
1-82445559-A-T p.Ile1006Phe missense LPHN2 1 81526 1.2266E-5 40763 0 NA
1-82445565-T-G p.Phe1008Val missense LPHN2 1 81644 1.22483E-5 40822 0 NA
1-82445582-G-C p.Leu1013Phe missense LPHN2 1 81786 1.2227E-5 40893 0 NA
1-82445589-A-AT p.Met1016fs frameshift LPHN2 1 81806 1.2224E-5 40903 0 3.1902E-5
1-82445591-G-T p.Met1016Ile missense LPHN2 1 81800 1.22249E-5 40900 0 NA
1-82445611-T-C p.Leu1023Ser missense LPHN2 2 81628 2.45014E-5 40814 0 3.1904E-5
1-82445625-A-G p.Ser1028Gly missense LPHN2 2 81466 2.45501E-5 40733 0 NA
1-82445626-G-C p.Ser1028Thr missense LPHN2 2 81408 2.45676E-5 40704 0 1.68862E-5
1-82445640-A-G p.Ile1033Val missense LPHN2 1 81024 1.2342E-5 40512 0 8.86635E-6
1-82446477-A-G c.3102-2A>G splice_acceptor LPHN2 1 49556 2.01792E-5 24778 0 8.81236E-6
1-82446479-T-C p.Asn1034Asn splice_region+synonymous LPHN2 1 49562 2.01767E-5 24781 0 4.40234E-6
1-82446487-G-A p.Arg1037His missense LPHN2 1 49596 2.01629E-5 24798 0 1.75024E-5
1-82446489-G-A p.Val1038Ile missense LPHN2 1 49736 2.01062E-5 24868 0 NA
1-82446496-A-G p.Asp1040Gly missense LPHN2 1 49922 2.00312E-5 24961 0 8.74722E-6
1-82446497-T-C p.Asp1040Asp synonymous LPHN2 1 49964 2.00144E-5 24982 0 8.74707E-6
1-82446511-C-T p.Thr1045Met missense LPHN2 3 50182 5.97824E-5 25091 0 2.62375E-5
1-82446518-A-G p.Leu1047Leu synonymous LPHN2 3 49992 6.00096E-5 24996 0 3.19734E-5
1-82446518-A-T p.Leu1047Phe missense LPHN2 1 49992 2.00032E-5 24996 0 NA
1-82446809-T-A p.Tyr917Asn missense+splice_region LPHN2 1 48100 2.079E-5 24050 0 7.77774E-6
1-82446821-A-G p.Lys921Glu missense LPHN2 1 48118 2.07822E-5 24059 0 9.57793E-5
1-82447488-C-G c.3147-4C>G splice_region LPHN2 1 83016 1.20459E-5 41508 0 NA
1-82447507-C-T p.Gly1054Gly synonymous LPHN2 4 83086 4.81429E-5 41543 0 4.1216E-5
1-82447513-C-T p.Phe1056Phe synonymous LPHN2 30 83086 3.61072E-4 41543 0 5.04032E-4
1-82447517-C-T p.Leu1058Phe missense LPHN2 1 83108 1.20325E-5 41554 0 1.64832E-5
1-82447522-G-T p.Leu1059Leu synonymous LPHN2 1 83120 1.20308E-5 41560 0 NA
1-82447569-A-G p.Glu1075Gly missense LPHN2 1 82930 1.20584E-5 41465 0 3.19061E-5
1-82447577-A-G p.Ile1078Val missense LPHN2 1 82886 1.20648E-5 41443 0 7.97964E-6
1-82447586-G-A p.Ala1081Thr missense LPHN2 9 82788 1.08711E-4 41394 0 5.18809E-5
1-82447588-A-C p.Ala1081Ala synonymous LPHN2 1 82778 1.20805E-5 41389 0 NA
1-82447590-A-G p.Tyr1082Cys missense LPHN2 2 82760 2.41663E-5 41380 0 8.25518E-6
1-82447622-G-A p.Val1093Met missense LPHN2 1 82552 1.21136E-5 41276 0 NA
1-82447628-A-G p.Ile1095Val missense LPHN2 3 82532 3.63495E-5 41266 0 1.19828E-5
1-82447641-A-T p.His1099Leu missense LPHN2 1 82374 1.21398E-5 41187 0 NA
1-82447644-G-A p.Cys1100Tyr missense LPHN2 3 82322 3.64423E-5 41161 0 3.99923E-6
1-82447647-C-T p.Ala1101Val missense LPHN2 1 82248 1.21584E-5 41124 0 5.06073E-4
1-82447656-A-G p.Lys1104Arg missense LPHN2 1 82100 1.21803E-5 41050 0 NA
1-82450269-A-G p.Val1106Val splice_region+synonymous LPHN2 1 82212 1.21637E-5 41106 0 NA
1-82450271-G-A p.Arg1107Gln missense LPHN2 2 82234 2.43208E-5 41117 0 2.80879E-5
1-82450272-A-T p.Arg1107Arg synonymous LPHN2 1 82276 1.21542E-5 41138 0 NA
1-82450297-C-T p.His1116Tyr missense LPHN2 3 82592 3.63231E-5 41296 0 4.125E-5
1-82450313-G-A p.Gly1121Glu missense LPHN2 1 82700 1.20919E-5 41350 0 3.98721E-6
1-82450315-G-A p.Gly1122Ser missense LPHN2 1 82708 1.20907E-5 41354 0 3.98705E-6
1-82450324-A-G p.Thr1125Ala missense LPHN2 1 82756 1.20837E-5 41378 0 3.18715E-5
1-82450329-G-A p.Glu1126Glu synonymous LPHN2 1 82784 1.20796E-5 41392 0 NA
1-82450330-A-G p.Ser1127Gly missense LPHN2 1 82768 1.2082E-5 41384 0 NA
1-82450334-C-T p.Pro1128Leu missense LPHN2 2 82790 2.41575E-5 41395 0 1.27502E-4
1-82450337-A-G p.His1129Arg missense LPHN2 3 82796 3.62336E-5 41398 0 NA
1-82450350-G-A p.Lys1133Lys synonymous LPHN2 1 82818 1.20747E-5 41409 0 3.98527E-6
1-82450351-G-A p.Ala1134Thr missense LPHN2 2 82814 2.41505E-5 41407 0 NA
1-82450362-C-A p.Thr1137Thr synonymous LPHN2 2 82798 2.41552E-5 41399 0 5.03525E-4
1-82450365-A-G p.Arg1138Arg synonymous LPHN2 1720 82748 0.020786 41374 32 0.0239132
1-82450382-C-A p.Ser1144Tyr missense LPHN2 27 82734 3.26347E-4 41367 0 1.43538E-4
1-82450385-C-G p.Ser1145Cys missense LPHN2 1 82732 1.20872E-5 41366 0 3.98702E-6
1-82450388-G-C p.Gly1146Ala missense LPHN2 4 82696 4.83699E-5 41348 0 6.25E-4
1-82450388-G-A p.Gly1146Asp missense LPHN2 1 82696 1.20925E-5 41348 0 NA
1-82450389-C-A p.Gly1146Gly synonymous LPHN2 32 82684 3.87016E-4 41342 0 0.0075
1-82450945-T-C p.Ser1149Ser splice_region+synonymous LPHN2 1 80864 1.23664E-5 40432 0 NA
1-82450947-G-A p.Arg1150His missense LPHN2 3 80934 3.70672E-5 40467 0 1.67774E-5
1-82450965-A-G p.Asn1156Ser missense LPHN2 1 81584 1.22573E-5 40792 0 NA
1-82450979-AAAC-A p.Gln1162del conservative_inframe_deletion LPHN2 1 81830 1.22205E-5 40915 0 NA
1-82450990-A-G p.Glu1164Glu synonymous LPHN2 4 81850 4.88699E-5 40925 0 5.04541E-4
1-82450996-T-C p.Ser1166Ser synonymous LPHN2 1 81884 1.22124E-5 40942 0 3.18654E-5
1-82451008-T-C p.Gly1170Gly synonymous LPHN2 1 81930 1.22055E-5 40965 0 4.01726E-6
1-82451010-A-C p.Asp1171Ala missense LPHN2 1 81882 1.22127E-5 40941 0 1.20693E-5
1-82451011-C-T p.Asp1171Asp synonymous LPHN2 1 81878 1.22133E-5 40939 0 4.02473E-6
1-82451016-A-G p.Asn1173Ser missense LPHN2 3 81864 3.66461E-5 40932 0 2.41309E-5
1-82451019-G-A p.Ser1174Asn missense LPHN2 1 81868 1.22148E-5 40934 0 4.03093E-6
1-82451020-C-T p.Ser1174Ser synonymous LPHN2 7 81862 8.55098E-5 40931 0 0.0015121
1-82451047-A-G c.3541+8A>G splice_region LPHN2 73 81110 9.00012E-4 40555 0 0.00127421
1-82451091-GT-G n.546delT splice_region LPHN2 4 78210 5.11444E-5 39105 0 9.5645E-5
1-82452577-T-A c.3542-8T>A splice_region LPHN2 1 76360 1.30959E-5 38180 0 9.01079E-6
1-82452578-A-T c.3542-7A>T splice_region LPHN2 2 76126 2.62722E-5 38063 0 5.41321E-4
1-82452579-C-T c.3542-6C>T splice_region LPHN2 4 76150 5.25279E-5 38075 0 3.85667E-4
1-82452579-C-CTTT c.3542-6_3542-5insTTT splice_region LPHN2 1 76244 1.31158E-5 38122 0 NA
1-82452588-T-C p.Met1182Thr missense LPHN2 1 76830 1.30157E-5 38415 0 3.50619E-5
1-82452617-C-A p.Leu1192Ile missense LPHN2 1 77304 1.29359E-5 38652 0 NA
1-82452624-G-A p.Arg1194Gln missense LPHN2 1 77416 1.29172E-5 38708 0 3.31631E-5
1-82452631-C-T p.His1196His synonymous LPHN2 2 77496 2.58078E-5 38748 0 3.49296E-5
1-82452632-G-A p.Gly1197Ser missense LPHN2 1 77514 1.29009E-5 38757 0 NA
1-82452648-A-G p.Tyr1202Cys missense LPHN2 1 77612 1.28846E-5 38806 0 NA
1-82452661-C-A p.Leu1206Leu synonymous LPHN2 2 77662 2.57526E-5 38831 0 NA
1-82452661-C-G p.Leu1206Leu synonymous LPHN2 1 77662 1.28763E-5 38831 0 8.72098E-6
1-82452662-G-A p.Ala1207Thr missense LPHN2 5 77662 6.43816E-5 38831 0 7.46646E-5
1-82452674-G-T p.Val1211Leu missense LPHN2 1 77690 1.28717E-5 38845 0 6.41684E-5
1-82452675-T-C p.Val1211Ala missense LPHN2 1 77696 1.28707E-5 38848 0 NA
1-82452681-A-G p.Asn1213Ser missense LPHN2 32 77696 4.11862E-4 38848 0 0.00168418
1-82452682-T-C p.Asn1213Asn synonymous LPHN2 1 77688 1.2872E-5 38844 0 4.15072E-6
1-82452685-C-T p.Ala1214Ala synonymous LPHN2 26 77690 3.34663E-4 38845 0 NA
1-82452686-C-T p.Pro1215Ser missense LPHN2 1 77696 1.28707E-5 38848 0 NA
1-82452694-T-G p.Ala1217Ala synonymous LPHN2 5 77668 6.43766E-5 38834 0 4.36765E-5
1-82452702-T-G p.Phe1220Cys missense LPHN2 1 77656 1.28773E-5 38828 0 NA
1-82452711-C-A p.Pro1223Gln missense+splice_region LPHN2 1 77646 1.2879E-5 38823 0 1.75205E-5
1-82452946-G-A n.353G>A splice_region LPHN2 1 75720 1.32066E-5 37860 0 2.43588E-5
1-82452984-C-A p.His1157Asn missense LPHN2 2 76242 2.62323E-5 38121 0 3.19061E-5
1-82452985-A-T p.His1157Leu missense LPHN2 1 76252 1.31144E-5 38126 0 NA
1-82453012-T-C p.Leu1166Ser missense LPHN2 1 75986 1.31603E-5 37993 0 NA
1-82453022-A-G p.Leu1169Leu synonymous LPHN2 653 75814 0.00861319 37907 6 0.00916821
1-82453031-C-T c.3510+6C>T splice_region LPHN2 1 75496 1.32457E-5 37748 0 NA
1-82453033-A-G c.3510+8A>G splice_region LPHN2 1 75380 1.32661E-5 37690 0 NA
1-82453547-C-G c.641-6C>G splice_region LPHN2 1 48682 2.05415E-5 24341 0 NA
1-82453556-C-A p.Thr215Asn missense LPHN2 53 48258 0.00109826 24129 0 0.00166511
1-82453566-G-A p.Glu218Glu synonymous LPHN2 1 47978 2.08429E-5 23989 0 NA
1-82455334-A-G c.3511-7A>G splice_region LPHN2 4 76262 5.24508E-5 38131 0 5.22184E-5
1-82455340-G-A c.3511-1G>A splice_acceptor LPHN2 2 76316 2.62068E-5 38158 0 1.73986E-5
1-82455344-C-CTA p.Leu1173fs frameshift LPHN2 3 76362 3.92866E-5 38181 0 3.18492E-5
1-82456071-T-G c.3542-4T>G splice_region LPHN2 1 82864 1.2068E-5 41432 0 NA
1-82456072-C-T c.3542-3C>T splice_region LPHN2 3 82880 3.61969E-5 41440 0 6.36902E-5
1-82456103-A-T p.Thr1190Thr synonymous LPHN2 1 82906 1.20619E-5 41453 0 3.98718E-5
1-82456107-G-C p.Ala1192Pro missense LPHN2 350 82886 0.00422267 41443 1 0.00414013
1-82456117-C-T p.Thr1195Ile missense LPHN2 1 82922 1.20595E-5 41461 0 1.19519E-5
1-82456123-C-T p.Pro1197Leu missense LPHN2 4 82936 4.823E-5 41468 0 3.18679E-5
1-82456124-G-A p.Pro1197Pro synonymous LPHN2 9 82916 1.08544E-4 41458 0 6.25E-4
1-82456128-A-G p.Asn1199Asp missense LPHN2 1 82942 1.20566E-5 41471 0 NA
1-82456145-C-T p.Asn1204Asn synonymous LPHN2 64 82954 7.71512E-4 41477 0 0.00159256
1-82456146-A-G p.Ser1205Gly missense LPHN2 3 82960 3.6162E-5 41480 0 8.2409E-6
1-82456153-C-T p.Ser1207Leu missense LPHN2 1 82942 1.20566E-5 41471 0 1.64813E-5
1-82456154-G-A p.Ser1207Ser synonymous LPHN2 75 82936 9.04312E-4 41468 0 0.00162358
1-82456154-G-C p.Ser1207Ser synonymous LPHN2 3 82936 3.61725E-5 41468 0 NA
1-82456158-C-A p.His1209Asn missense LPHN2 1 82956 1.20546E-5 41478 0 NA
1-82456164-G-C p.Gly1211Arg missense LPHN2 1 82960 1.2054E-5 41480 0 NA
1-82456165-G-T p.Gly1211Val missense LPHN2 169 82962 0.00203708 41481 3 0.0175
1-82456172-T-C p.Tyr1213Tyr synonymous LPHN2 1 82966 1.20531E-5 41483 0 5.03525E-4
1-82456174-A-G p.Asn1214Ser missense LPHN2 1 82974 1.2052E-5 41487 0 3.98168E-6
1-82456182-G-A p.Val1217Met missense LPHN2 43 82942 5.18435E-4 41471 0 5.03525E-4
1-82456197-T-C p.Cys1222Arg missense LPHN2 2 82922 2.41191E-5 41461 0 9.06379E-5
1-82456198-G-A p.Cys1222Tyr missense LPHN2 1 82918 1.20601E-5 41459 0 NA
1-82456209-C-A p.Leu1226Met missense LPHN2 3 82908 3.61847E-5 41454 0 1.91058E-4
1-82456226-T-A p.Phe1231Leu missense LPHN2 1 82862 1.20683E-5 41431 0 8.76333E-5
1-82456229-G-GA p.Met1234fs frameshift LPHN2 3 82836 3.62161E-5 41418 0 3.1841E-5
1-82456238-C-T p.Ile1235Ile synonymous LPHN2 1 82822 1.20741E-5 41411 0 3.98343E-6
1-82456239-A-G p.Ile1236Val missense LPHN2 1 82812 1.20755E-5 41406 0 NA
1-82456256-C-G p.His1241Gln missense LPHN2 1 82826 1.20735E-5 41413 0 3.98397E-6
1-82456258-A-G p.Asn1242Ser missense LPHN2 1 82826 1.20735E-5 41413 0 8.24253E-6
1-82456266-C-CG p.Ser1247fs frameshift LPHN2 1 82814 1.20753E-5 41407 0 NA
1-82456266-C-A p.Arg1245Arg synonymous LPHN2 2 82814 2.41505E-5 41407 0 3.9846E-6
1-82456266-C-T p.Arg1245Trp missense LPHN2 1 82814 1.20753E-5 41407 0 3.9846E-6
1-82456270-G-T p.Gly1246Val missense LPHN2 1 82812 1.20755E-5 41406 0 NA
1-82456271-C-T p.Gly1246Gly synonymous LPHN2 1 82816 1.2075E-5 41408 0 NA
1-82456274-C-G p.Ser1247Arg missense LPHN2 2 82812 2.41511E-5 41406 0 NA
1-82456276-G-A p.Ser1248Asn missense LPHN2 18 82800 2.17391E-4 41400 2 0.00151057
1-82456278-A-C p.Lys1249Gln missense LPHN2 2 82802 2.4154E-5 41401 0 3.1841E-5
1-82456291-T-G p.Leu1253Arg missense LPHN2 2 82816 2.41499E-5 41408 0 NA
1-82456292-C-T p.Leu1253Leu synonymous LPHN2 1 82816 1.2075E-5 41408 0 1.64829E-5
1-82456293-G-A p.Glu1254Lys missense LPHN2 2 82808 2.41523E-5 41404 0 1.64834E-5
1-82456296-C-T p.Leu1255Phe missense LPHN2 2 82804 2.41534E-5 41402 1 3.98305E-6
1-82456296-C-CTCA p.Leu1255_Thr1256insIle disruptive_inframe_insertion LPHN2 1 82804 1.20767E-5 41402 0 1.64815E-5
1-82456297-T-C p.Leu1255Pro missense LPHN2 1 82804 1.20767E-5 41402 0 7.96641E-6
1-82456300-C-G p.Thr1256Arg missense LPHN2 2 82798 2.41552E-5 41399 0 3.98368E-6
1-82456301-G-A p.Thr1256Thr synonymous LPHN2 765 82776 0.00924181 41388 15 0.0185067
1-82456308-G-A p.Val1259Ile missense LPHN2 105 82756 0.00126879 41378 0 0.00315327
1-82456309-T-G p.Val1259Gly missense LPHN2 2 82752 2.41686E-5 41376 0 8.24063E-6
1-82456331-C-T p.Ser1266Ser synonymous LPHN2 1 82610 1.21051E-5 41305 0 2.78916E-5
1-82456332-A-G p.Ser1267Gly missense LPHN2 15 82604 1.81589E-4 41302 0 9.97099E-4
1-82456341-G-A p.Asp1270Asn missense LPHN2 13 82516 1.57545E-4 41258 0 9.88826E-5
1-82456351-T-C p.Ile1273Thr missense LPHN2 2 82488 2.4246E-5 41244 0 8.23954E-6
1-82456360-A-G p.Asp1276Gly missense LPHN2 1 82430 1.21315E-5 41215 0 NA
1-82456362-GC-G p.Ala1277fs frameshift LPHN2 1 82414 1.21339E-5 41207 0 NA
1-82456375-T-C p.Met1281Thr missense LPHN2 2 82418 2.42665E-5 41209 0 3.98518E-6
1-82456381-G-A p.Ser1283Asn missense LPHN2 28 82384 3.39872E-4 41192 0 0.00173877
1-82456382-C-T p.Ser1283Ser synonymous LPHN2 6 82378 7.2835E-5 41189 0 4.78259E-5
1-82456383-G-A p.Asp1284Asn missense LPHN2 1 82414 1.21339E-5 41207 0 1.64823E-5
1-82456396-T-A p.Leu1288Gln missense LPHN2 5 82456 6.06384E-5 41228 0 1.59394E-5
1-82456403-C-G p.Leu1290Leu synonymous LPHN2 1 82504 1.21206E-5 41252 0 3.18593E-5
1-82456405-A-G p.His1291Arg missense LPHN2 1 82562 1.21121E-5 41281 0 3.98394E-6
1-82456406-T-A p.His1291Gln missense LPHN2 1 82564 1.21118E-5 41282 0 3.18573E-5
1-82456418-C-T p.Leu1295Leu synonymous LPHN2 1 82624 1.2103E-5 41312 0 NA
1-82456419-G-A p.Glu1296Lys missense LPHN2 15 82642 1.81506E-4 41321 1 0.0040282
1-82456428-C-G p.Leu1299Val missense LPHN2 13 82694 1.57206E-4 41347 0 2.47255E-5
1-82456432-T-C p.Ile1300Thr missense LPHN2 55 82686 6.65167E-4 41343 0 0.00152993
1-82456440-C-T p.Arg1303Trp missense LPHN2 1 82638 1.2101E-5 41319 0 1.64848E-5
1-82456441-G-A p.Arg1303Gln missense LPHN2 4 82656 4.83933E-5 41328 0 5.03525E-4
1-82456451-C-T p.Ser1306Ser synonymous LPHN2 2 82668 2.41932E-5 41334 0 6.37389E-5
1-82456457-G-A p.Leu1308Leu synonymous LPHN2 14 82658 1.69373E-4 41329 0 2.231E-4
1-82456473-A-G p.Lys1314Glu missense LPHN2 2 82598 2.42137E-5 41299 0 NA
1-82456482-T-A p.Ser1317Thr missense LPHN2 1 82556 1.2113E-5 41278 0 2.47345E-5
1-82456484-C-T p.Ser1317Ser synonymous LPHN2 7 82510 8.48382E-5 41255 0 6.25E-4
1-82456485-G-A p.Glu1318Lys missense LPHN2 19 82524 2.30236E-4 41262 0 1.48417E-4
1-82456496-C-A p.Asp1321Glu missense LPHN2 1 82468 1.21259E-5 41234 0 NA
1-82456496-C-T p.Asp1321Asp synonymous LPHN2 1 82468 1.21259E-5 41234 0 NA
1-82456501-A-G p.Tyr1323Cys missense LPHN2 258 82482 0.00312796 41241 1 0.0060423
1-82456502-T-C p.Tyr1323Tyr synonymous LPHN2 1 82478 1.21244E-5 41239 0 NA
1-82456516-C-T p.Thr1328Ile missense LPHN2 3 82448 3.63866E-5 41224 0 3.29766E-5
1-82456537-T-C p.Leu1335Pro missense LPHN2 1 82438 1.21303E-5 41219 0 4.38565E-5
1-82456543-C-T p.Ser1337Phe missense LPHN2 2 82410 2.42689E-5 41205 0 NA
1-82456544-C-A p.Ser1337Ser synonymous LPHN2 2 82404 2.42707E-5 41202 0 6.25E-4
1-82456552-G-A p.Arg1340Lys missense LPHN2 2 82386 2.4276E-5 41193 0 3.98743E-6
1-82456555-A-G p.Asp1341Gly missense LPHN2 1 82358 1.21421E-5 41179 0 7.97531E-6
1-82456556-C-A p.Asp1341Glu missense LPHN2 9 82368 1.09266E-4 41184 0 6.59511E-5
1-82456559-T-C p.Ser1342Ser synonymous LPHN2 3 82356 3.64272E-5 41178 0 3.98769E-5
1-82456560-C-G p.Leu1343Val missense LPHN2 1 82364 1.21412E-5 41182 0 3.98807E-6
1-82456579-A-G p.Asn1349Ser missense LPHN2 1 82306 1.21498E-5 41153 0 3.98931E-6
1-82456581-C-G p.Leu1350Val missense LPHN2 1 82308 1.21495E-5 41154 0 NA
1-82456585-G-A p.Arg1351Lys missense LPHN2 2943 82230 0.0357899 41115 67 0.050856
1-82456586-AGACTCTCCCTATCCG-A p.Asp1352_Pro1356del disruptive_inframe_deletion LPHN2 12 82286 1.45833E-4 41143 0 4.38894E-5
1-82456588-A-G p.Asp1352Gly missense LPHN2 1 82262 1.21563E-5 41131 0 NA
1-82456591-C-T p.Ser1353Phe missense LPHN2 1 82248 1.21584E-5 41124 0 NA
1-82456597-A-C p.Tyr1355Ser missense LPHN2 1 82210 1.2164E-5 41105 0 NA
1-82456597-A-G p.Tyr1355Cys missense LPHN2 2 82210 2.43279E-5 41105 0 NA
1-82456599-C-G p.Pro1356Ala missense LPHN2 146 82186 0.00177646 41093 1 0.014375
1-82456600-C-T p.Pro1356Leu missense LPHN2 8 82176 9.7352E-5 41088 0 9.56023E-5
1-82456601-G-A p.Pro1356Pro synonymous LPHN2 10 82178 1.21687E-4 41089 0 3.18735E-4
1-82456602-G-C p.Glu1357Gln missense LPHN2 1 82162 1.21711E-5 41081 0 6.37227E-5
1-82456611-C-A p.Pro1360Thr missense LPHN2 2 82158 2.43433E-5 41079 0 NA
1-82456635-C-G p.Pro1368Ala missense LPHN2 1 82050 1.21877E-5 41025 0 NA
1-82456642-G-A p.Arg1370Lys missense LPHN2 2 82064 2.43712E-5 41032 0 4.80854E-5
1-82456646-G-C p.Arg1371Ser missense LPHN2 1 82050 1.21877E-5 41025 0 NA
1-82456652-G-T p.Glu1373Asp missense LPHN2 1 82058 1.21865E-5 41029 0 3.18532E-5
1-82456669-A-G p.Tyr1379Cys missense LPHN2 1 82124 1.21767E-5 41062 0 NA
1-82456688-T-A p.Leu1385Leu synonymous LPHN2 1 82204 1.21649E-5 41102 0 NA
1-82456694-T-C p.Ala1387Ala synonymous LPHN2 1 82222 1.21622E-5 41111 0 NA
1-82456699-A-G p.His1389Arg missense LPHN2 1 82278 1.21539E-5 41139 0 NA
1-82456702-A-G p.Gln1390Arg missense LPHN2 2 82302 2.43007E-5 41151 0 NA
1-82456719-C-G p.Gln1396Glu missense LPHN2 2 82412 2.42683E-5 41206 0 NA
1-82456723-T-G p.Ile1397Ser missense LPHN2 1 82468 1.21259E-5 41234 0 NA
1-82456738-G-A p.Ser1402Asn missense LPHN2 2 82502 2.42418E-5 41251 0 8.40887E-6
1-82456749-A-G p.Ile1406Val missense LPHN2 2 82346 2.42878E-5 41173 0 2.00932E-5
1-82456762-A-C p.Asn1410Thr missense LPHN2 1 82042 1.21889E-5 41021 0 3.18431E-5
1-82456763-C-T p.Asn1410Asn synonymous LPHN2 3 82028 3.65729E-5 41014 0 3.40524E-5
1-82456770-G-A p.Gly1413Arg missense LPHN2 1 81892 1.22112E-5 40946 0 8.54642E-6
1-82456773-T-C p.Cys1414Arg missense LPHN2 1 81770 1.22294E-5 40885 0 NA
1-82456778-T-G p.Ile1415Met missense LPHN2 1 81654 1.22468E-5 40827 0 NA
1-82456786-G-T p.Gly1418Val missense LPHN2 2 81518 2.45345E-5 40759 0 8.09147E-6
1-82456787-A-T p.Gly1418Gly synonymous LPHN2 1 81486 1.2272E-5 40743 0 6.3678E-5
1-82456807-T-G p.Met1425Arg missense LPHN2 1 81268 1.2305E-5 40634 0 8.77932E-6
1-82456816-T-C p.Val1428Ala missense LPHN2 1 81206 1.23144E-5 40603 0 4.10028E-6
1-82458104-A-G c.*1275A>G splice_region LPHN2 1 44084 2.2684E-5 22042 0 NA
1-82458120-A-T n.3151A>T splice_region LPHN2 12 43978 2.72864E-4 21989 0 2.2293E-4