Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
21-28296374-AAC-A p.Cys930fs frameshift ADAMTS5 1 81796 1.22255E-5 40898 0 NA
21-28296387-C-G p.Leu926Phe missense ADAMTS5 1 82188 1.21672E-5 41094 0 NA
21-28296389-A-G p.Leu926Leu synonymous ADAMTS5 1969 82164 0.0239643 41082 19 0.0575
21-28296402-C-T p.Ala921Ala synonymous ADAMTS5 17 82498 2.06066E-4 41249 0 1.34905E-4
21-28296403-G-A p.Ala921Val missense ADAMTS5 3 82498 3.63645E-5 41249 0 9.55171E-5
21-28296414-T-C p.Gln917Gln synonymous ADAMTS5 11 82626 1.3313E-4 41313 0 3.9901E-6
21-28296425-G-A p.Pro914Ser missense ADAMTS5 1 82680 1.20948E-5 41340 0 3.18451E-5
21-28296426-A-G p.Cys913Cys synonymous ADAMTS5 1 82692 1.20931E-5 41346 0 3.98613E-6
21-28296433-T-C p.Lys911Arg missense ADAMTS5 35 82724 4.23094E-4 41362 0 3.18492E-5
21-28296435-T-C p.Ala910Ala synonymous ADAMTS5 1 82734 1.20869E-5 41367 0 8.26351E-6
21-28296445-C-T p.Arg907Gln missense ADAMTS5 3 82742 3.62573E-5 41371 0 5.03525E-4
21-28296446-G-A p.Arg907Trp missense ADAMTS5 5 82748 6.04244E-5 41374 0 0.001875
21-28296448-T-G p.Asn906Thr missense ADAMTS5 3 82756 3.62511E-5 41378 0 6.36821E-5
21-28296456-C-T p.Gln903Gln synonymous ADAMTS5 1 82742 1.20858E-5 41371 0 3.1835E-5
21-28296457-T-C p.Gln903Arg missense ADAMTS5 1 82736 1.20866E-5 41368 0 2.47321E-5
21-28296467-C-T p.Val900Met missense ADAMTS5 4 82690 4.83734E-5 41345 0 3.1835E-5
21-28296469-G-A p.Thr899Met missense ADAMTS5 5 82684 6.04712E-5 41342 0 9.55231E-5
21-28296477-G-A p.His896His synonymous ADAMTS5 2 82672 2.4192E-5 41336 0 NA
21-28296484-C-T p.Gly894Asp missense ADAMTS5 4 82684 4.8377E-5 41342 0 9.55049E-5
21-28296487-G-A p.Thr893Ile missense ADAMTS5 3 82704 3.62739E-5 41352 0 NA
21-28296487-G-C p.Thr893Arg missense ADAMTS5 1 82704 1.20913E-5 41352 0 NA
21-28296495-G-A p.Thr890Thr synonymous ADAMTS5 1 82662 1.20975E-5 41331 0 NA
21-28296501-A-C p.Ser888Ser synonymous ADAMTS5 4 82668 4.83863E-5 41334 0 1.48351E-4
21-28296504-G-A p.Cys887Cys synonymous ADAMTS5 1 82672 1.2096E-5 41336 0 NA
21-28296509-C-A p.Ala886Ser missense ADAMTS5 2 82652 2.41978E-5 41326 0 NA
21-28296510-G-T p.Leu885Leu synonymous ADAMTS5 2 82682 2.41891E-5 41341 0 NA
21-28296518-G-A p.Pro883Ser missense ADAMTS5 1 82702 1.20916E-5 41351 0 3.98298E-6
21-28296522-C-T p.Thr881Thr synonymous ADAMTS5 2 82712 2.41803E-5 41356 0 1.64796E-4
21-28296523-G-A p.Thr881Met missense ADAMTS5 2 82716 2.41791E-5 41358 0 8.23981E-6
21-28296524-T-A p.Thr881Ser missense ADAMTS5 4 82724 4.83536E-5 41362 0 3.1839E-5
21-28296525-G-T p.Val880Val synonymous ADAMTS5 2 82720 2.41779E-5 41360 0 NA
21-28296534-C-T p.Pro877Pro synonymous ADAMTS5 3 82742 3.62573E-5 41371 0 3.29571E-5
21-28296535-G-A p.Pro877Leu missense ADAMTS5 4 82748 4.83395E-5 41374 0 6.36902E-5
21-28296540-C-T p.Ser875Ser synonymous ADAMTS5 2 82790 2.41575E-5 41395 0 5.03525E-4
21-28296541-G-A p.Ser875Leu missense ADAMTS5 3 82796 3.62336E-5 41398 0 0.00125
21-28296545-T-C p.Thr874Ala missense ADAMTS5 1 82834 1.20723E-5 41417 0 NA
21-28296550-G-T p.Ser872* stop_gained ADAMTS5 1 82844 1.20709E-5 41422 0 1.59256E-4
21-28296552-T-C p.Gly871Gly synonymous ADAMTS5 2 82840 2.41429E-5 41420 0 1.64761E-5
21-28296559-T-A p.Lys869Ile missense ADAMTS5 4 82854 4.82777E-5 41427 0 1.91192E-4
21-28296570-A-G p.His865His synonymous ADAMTS5 5 82854 6.03471E-5 41427 0 1.23563E-4
21-28296601-G-A p.Ser855Phe missense ADAMTS5 3 82836 3.62161E-5 41418 0 1.59261E-5
21-28296610-G-C p.Pro852Arg missense ADAMTS5 1 82806 1.20764E-5 41403 0 NA
21-28296633-A-C p.Asp844Glu missense ADAMTS5 1 82782 1.20799E-5 41391 0 NA
21-28296640-G-T p.Pro842Gln missense ADAMTS5 2 82794 2.41563E-5 41397 0 NA
21-28296677-G-A p.Leu830Leu synonymous ADAMTS5 228 82856 0.00275176 41428 0 0.00534793
21-28296688-G-A p.Thr826Met missense ADAMTS5 3 82904 3.61864E-5 41452 0 3.58346E-5
21-28296700-C-T p.Gly822Asp missense ADAMTS5 2 82926 2.41179E-5 41463 0 NA
21-28296714-G-T p.Phe817Leu missense ADAMTS5 1 82974 1.2052E-5 41487 0 7.96299E-6
21-28296723-C-G p.Arg814Ser missense ADAMTS5 45 82994 5.42208E-4 41497 1 4.20133E-4
21-28296737-C-T p.Gly810Ser missense ADAMTS5 1 83022 1.2045E-5 41511 0 3.18431E-5
21-28296738-G-A p.Ser809Ser synonymous ADAMTS5 301 83022 0.00362554 41511 5 0.00557289
21-28296760-T-C p.Asn802Ser missense ADAMTS5 1 83096 1.20343E-5 41548 0 8.23723E-6
21-28296764-T-G p.Ile801Leu missense ADAMTS5 1 83098 1.2034E-5 41549 0 3.1839E-5
21-28296766-T-C p.Asp800Gly missense ADAMTS5 2 83102 2.40668E-5 41551 0 NA
21-28296769-A-G p.Ile799Thr missense ADAMTS5 2 83116 2.40628E-5 41558 0 NA
21-28296771-G-T p.Ile798Ile synonymous ADAMTS5 1 83118 1.20311E-5 41559 0 NA
21-28296822-G-A p.Asn781Asn synonymous ADAMTS5 2 83138 2.40564E-5 41569 0 3.97947E-6
21-28296831-T-C p.Lys778Lys synonymous ADAMTS5 1 83154 1.20259E-5 41577 0 8.23696E-6
21-28296833-T-C p.Lys778Glu missense ADAMTS5 1 83140 1.20279E-5 41570 0 NA
21-28296863-G-A p.Gln768* stop_gained ADAMTS5 1 83112 1.2032E-5 41556 0 NA
21-28296878-A-G p.Phe763Leu missense ADAMTS5 1 83096 1.20343E-5 41548 0 3.98134E-6
21-28296883-C-T p.Arg761Gln missense ADAMTS5 1 83092 1.20349E-5 41546 0 NA
21-28296892-A-T p.Ile758Lys missense ADAMTS5 1 83076 1.20372E-5 41538 0 NA
21-28296897-G-C p.Thr756Thr synonymous ADAMTS5 1 83078 1.20369E-5 41539 0 NA
21-28296921-C-T p.Val748Val synonymous ADAMTS5 1 83006 1.20473E-5 41503 0 3.18674E-5
21-28296924-G-A p.Asp747Asp synonymous ADAMTS5 41 83008 4.93928E-4 41504 0 8.28236E-4
21-28296935-C-T p.Gly744Ser missense ADAMTS5 1 82948 1.20557E-5 41474 0 NA
21-28296947-T-G c.2226-8A>C splice_region ADAMTS5 1 82794 1.20782E-5 41397 0 1.7183E-5
21-28302229-A-G p.Ile734Thr missense ADAMTS5 3 83076 3.61115E-5 41538 0 1.994E-5
21-28302240-G-C p.Ser730Arg missense ADAMTS5 6 83112 7.21917E-5 41556 0 NA
21-28302242-T-C p.Ser730Gly missense ADAMTS5 1 83128 1.20296E-5 41564 0 NA
21-28302261-T-C p.Val723Val synonymous ADAMTS5 2 83166 2.40483E-5 41583 0 1.19384E-5
21-28302264-T-A p.Gly722Gly synonymous ADAMTS5 1 83174 1.2023E-5 41587 0 NA
21-28302266-C-T p.Gly722Arg missense ADAMTS5 3 83180 3.60664E-5 41590 0 6.25E-4
21-28302267-G-A p.Cys721Cys synonymous ADAMTS5 5 83160 6.01251E-5 41580 0 6.37999E-5
21-28302270-C-G p.Lys720Asn missense ADAMTS5 1 83192 1.20204E-5 41596 0 3.97852E-6
21-28302276-A-G p.Tyr718Tyr synonymous ADAMTS5 1 83202 1.20189E-5 41601 0 3.29478E-5
21-28302291-G-T p.Gly713Gly synonymous ADAMTS5 7 83194 8.41407E-5 41597 0 1.91241E-4
21-28302292-C-T p.Gly713Asp missense ADAMTS5 1 83192 1.20204E-5 41596 0 8.23669E-6
21-28302303-G-A p.Asp709Asp synonymous ADAMTS5 3 83184 3.60646E-5 41592 0 6.37836E-5
21-28302326-T-TC p.Lys702fs frameshift ADAMTS5 1 83066 1.20386E-5 41533 0 NA
21-28302331-C-T p.Arg700Gln missense ADAMTS5 2 83040 2.40848E-5 41520 0 3.58289E-5
21-28302332-G-T p.Arg700Arg synonymous ADAMTS5 3 83028 3.61324E-5 41514 0 3.19428E-5
21-28302332-G-A p.Arg700Trp missense ADAMTS5 1 83028 1.20441E-5 41514 0 6.38855E-5
21-28302334-A-G p.Val699Ala missense ADAMTS5 1 83016 1.20459E-5 41508 0 NA
21-28302335-C-T p.Val699Ile missense ADAMTS5 7 83002 8.43353E-5 41501 0 9.55399E-5
21-28302336-G-A p.Cys698Cys synonymous ADAMTS5 4 82988 4.81997E-5 41494 0 0.00125
21-28302341-C-G p.Val697Leu missense ADAMTS5 1 82970 1.20525E-5 41485 0 3.98092E-6
21-28302341-C-T p.Val697Ile missense ADAMTS5 1 82970 1.20525E-5 41485 0 1.64745E-5
21-28302342-G-A p.Ser696Ser synonymous ADAMTS5 5 82950 6.02773E-5 41475 0 5.03525E-4
21-28302352-T-G p.Tyr693Ser missense ADAMTS5 1 82908 1.20616E-5 41454 0 NA
21-28302354-C-T p.Leu692Leu synonymous ADAMTS5 220 82882 0.00265438 41441 3 0.00583509
21-28302354-CA-TG p.Leu692Pro missense ADAMTS5 13 82886 1.56842E-4 41443 2 NA
21-28302355-A-G p.Leu692Pro missense ADAMTS5 69501 79350 0.875879 39675 30653 0.891742
21-28302372-A-G p.Asp686Asp synonymous ADAMTS5 2 82676 2.41908E-5 41338 0 NA
21-28302374-C-T p.Asp686Asn missense ADAMTS5 1 82610 1.21051E-5 41305 0 3.59327E-5
21-28302375-G-A p.Thr685Thr synonymous ADAMTS5 11 82558 1.3324E-4 41279 0 0.001875
21-28304320-T-C c.2049+3A>G splice_region ADAMTS5 1 83140 1.20279E-5 41570 0 NA
21-28304333-A-C p.Phe680Cys missense ADAMTS5 1 83200 1.20192E-5 41600 0 NA
21-28304341-A-C p.Tyr677* stop_gained ADAMTS5 1 83226 1.20155E-5 41613 0 NA
21-28304386-C-T p.Ala662Ala synonymous ADAMTS5 2 83276 2.40165E-5 41638 0 1.98918E-5
21-28304387-G-A p.Ala662Val missense ADAMTS5 1 83272 1.20088E-5 41636 0 3.58098E-5
21-28304390-G-A p.Pro661Leu missense ADAMTS5 1 83270 1.20091E-5 41635 0 NA
21-28304407-T-C p.Lys655Lys synonymous ADAMTS5 1 83276 1.20083E-5 41638 0 1.64815E-5
21-28304409-TG-T p.Lys655fs frameshift ADAMTS5 2 83272 2.40177E-5 41636 0 3.97798E-6
21-28304410-G-A p.Pro654Pro synonymous ADAMTS5 3 83272 3.60265E-5 41636 0 1.19351E-5
21-28304435-A-T p.Val646Asp missense ADAMTS5 2 83256 2.40223E-5 41628 0 NA
21-28304443-T-C p.Ala643Ala synonymous ADAMTS5 1 83248 1.20123E-5 41624 0 NA
21-28304446-A-G p.Asp642Asp synonymous ADAMTS5 1 83228 1.20152E-5 41614 0 3.18492E-5
21-28304451-A-G p.Ser641Pro missense ADAMTS5 1 83224 1.20158E-5 41612 0 NA
21-28304459-C-T p.Gly638Asp missense ADAMTS5 1 83208 1.20181E-5 41604 0 8.24987E-6
21-28304469-C-T p.Ala635Thr missense ADAMTS5 1 83184 1.20215E-5 41592 0 NA
21-28304476-C-CTCCTGACCTTGTGATCCACCCTCCTCGGCCCCCTAAAG p.Gln632fs frameshift ADAMTS5 1 83174 1.2023E-5 41587 0 NA
21-28304483-T-C p.His630Arg missense ADAMTS5 1 83154 1.20259E-5 41577 0 6.25E-4
21-28304486-C-T p.Arg629His missense ADAMTS5 8 83128 9.62371E-5 41564 0 3.56006E-4
21-28304494-T-C p.Lys626Lys synonymous ADAMTS5 1 83096 1.20343E-5 41548 0 4.00663E-6
21-28305175-C-T c.1873+5G>A splice_region ADAMTS5 2 82706 2.4182E-5 41353 0 6.37064E-5
21-28305176-G-A c.1873+4C>T splice_region ADAMTS5 6 82734 7.25216E-5 41367 0 0.00125
21-28305180-C-T p.Gly625Ser missense+splice_region ADAMTS5 1 82822 1.20741E-5 41411 0 NA
21-28305185-G-T p.Pro623His missense ADAMTS5 1 82816 1.2075E-5 41408 0 NA
21-28305189-G-C p.Pro622Ala missense ADAMTS5 1 82858 1.20688E-5 41429 0 NA
21-28305194-G-A p.Pro620Leu missense ADAMTS5 1 82882 1.20653E-5 41441 0 NA
21-28305195-G-A p.Pro620Ser missense ADAMTS5 5 82872 6.0334E-5 41436 0 1.00746E-4
21-28305199-G-A p.Leu618Leu synonymous ADAMTS5 6 82936 7.23449E-5 41468 0 2.50941E-5
21-28305202-A-G p.Ser617Ser synonymous ADAMTS5 1593 82892 0.0192178 41446 26 0.0194772
21-28305212-C-T p.Arg614His missense ADAMTS5 11331 82586 0.137202 41293 787 0.138105
21-28305213-G-A p.Arg614Cys missense ADAMTS5 2 82968 2.41057E-5 41484 0 8.28144E-6
21-28305235-G-A p.Cys606Cys synonymous ADAMTS5 2 82996 2.40975E-5 41498 0 3.18532E-5
21-28305242-C-T p.Arg604His missense ADAMTS5 1 82980 1.20511E-5 41490 0 5.7835E-5
21-28305243-G-A p.Arg604Cys missense ADAMTS5 2 82990 2.40993E-5 41495 0 5.97248E-5
21-28305247-G-A p.Asn602Asn synonymous ADAMTS5 8 83002 9.63832E-5 41501 0 1.32194E-4
21-28305267-T-A p.Asn596Tyr missense ADAMTS5 3 83042 3.61263E-5 41521 0 1.90451E-4
21-28305278-C-T p.Arg592His missense ADAMTS5 1 83070 1.2038E-5 41535 0 3.98314E-6
21-28305291-G-T p.Gln588Lys missense ADAMTS5 1 83082 1.20363E-5 41541 0 NA
21-28305299-C-T p.Gly585Glu missense ADAMTS5 1 83098 1.2034E-5 41549 0 NA
21-28305311-C-T p.Arg581His missense ADAMTS5 1 83092 1.20349E-5 41546 0 1.67286E-5
21-28305312-G-A p.Arg581Cys missense ADAMTS5 3 83100 3.61011E-5 41550 0 6.37267E-5
21-28305315-A-C p.Ser580Ala missense ADAMTS5 6 83098 7.22039E-5 41549 0 6.37552E-5
21-28305322-G-C p.Gly577Gly synonymous ADAMTS5 4 83098 4.81359E-5 41549 0 3.18674E-5
21-28305324-C-T p.Gly577Ser missense ADAMTS5 1563 83072 0.018815 41536 30 0.044375
21-28305339-A-G p.Ser572Pro missense ADAMTS5 1 83080 1.20366E-5 41540 0 4.00195E-6
21-28305351-C-T p.Gly568Ser missense ADAMTS5 1 83048 1.20412E-5 41524 0 4.01674E-6
21-28305355-G-A p.Ser566Ser synonymous ADAMTS5 1 83014 1.20462E-5 41507 0 4.03314E-5
21-28305359-G-C p.Ser565* stop_gained ADAMTS5 1 82984 1.20505E-5 41492 0 NA
21-28305361-C-T p.Thr564Thr splice_region+synonymous ADAMTS5 4 82958 4.82172E-5 41479 0 5.03525E-4
21-28305362-G-A p.Thr564Met missense+splice_region ADAMTS5 4 82958 4.82172E-5 41479 0 2.87947E-5
21-28305368-A-G c.1690-5T>C splice_region ADAMTS5 1 82926 1.20589E-5 41463 0 NA
21-28306779-A-G c.1689+6T>C splice_region ADAMTS5 2 82696 2.4185E-5 41348 0 NA
21-28306788-A-G p.Tyr562Tyr synonymous ADAMTS5 1 82796 1.20779E-5 41398 0 NA
21-28306791-A-G p.Tyr561Tyr synonymous ADAMTS5 2 82864 2.41359E-5 41432 0 NA
21-28306837-C-A p.Arg546Ile missense ADAMTS5 3 83098 3.6102E-5 41549 0 1.19386E-5
21-28306849-C-T p.Cys542Tyr missense ADAMTS5 1 83134 1.20288E-5 41567 0 NA
21-28306851-A-G p.Pro541Pro synonymous ADAMTS5 1 83136 1.20285E-5 41568 0 2.47121E-5
21-28306853-G-T p.Pro541Thr missense ADAMTS5 2 83134 2.40575E-5 41567 0 1.64756E-5
21-28306854-C-T p.Thr540Thr synonymous ADAMTS5 9 83140 1.08251E-4 41570 0 6.25E-4
21-28306855-G-A p.Thr540Met missense ADAMTS5 3 83138 3.60846E-5 41569 0 6.37064E-5
21-28306857-C-T p.Gly539Gly synonymous ADAMTS5 2 83154 2.40518E-5 41577 0 1.19373E-5
21-28306866-C-T p.Ala536Ala synonymous ADAMTS5 4 83156 4.81024E-5 41578 0 5.03525E-4
21-28306867-G-A p.Ala536Val missense ADAMTS5 2 83154 2.40518E-5 41577 0 6.37552E-5
21-28306869-A-C p.Pro535Pro synonymous ADAMTS5 1 83160 1.2025E-5 41580 0 NA
21-28306886-G-A p.Leu530Leu synonymous ADAMTS5 23 83120 2.76708E-4 41560 0 6.37186E-4
21-28306893-C-G p.Met527Ile missense ADAMTS5 1 83114 1.20317E-5 41557 0 NA
21-28306899-G-T p.Gly525Gly synonymous ADAMTS5 2 83074 2.40749E-5 41537 0 NA
21-28306907-G-A p.Arg523Cys missense ADAMTS5 2 83022 2.409E-5 41511 0 1.64799E-5
21-28306914-AG-A p.Ala520fs frameshift ADAMTS5 4 83004 4.81904E-5 41502 0 3.98051E-6
21-28306919-A-G p.Cys519Arg missense ADAMTS5 3 82978 3.61542E-5 41489 0 1.59228E-5
21-28306937-C-T p.Val513Ile missense ADAMTS5 4 82844 4.82835E-5 41422 0 NA
21-28306946-C-T p.Gly510Ser missense ADAMTS5 2 82818 2.41493E-5 41409 0 2.47264E-5
21-28306947-G-A p.Pro509Pro synonymous ADAMTS5 2 82802 2.4154E-5 41401 0 4.38223E-5
21-28306947-G-T p.Pro509Pro synonymous ADAMTS5 1 82802 1.2077E-5 41401 0 3.29788E-5
21-28306955-C-T p.Val507Met missense ADAMTS5 2 82770 2.41633E-5 41385 0 6.36943E-5
21-28306955-C-G p.Val507Leu missense ADAMTS5 1 82770 1.20817E-5 41385 0 3.18471E-5
21-28306962-C-T p.Glu504Glu synonymous ADAMTS5 2 82756 2.41674E-5 41378 0 7.96578E-6
21-28306971-G-A p.Phe501Phe synonymous ADAMTS5 8 82758 9.66674E-5 41379 0 6.37064E-5
21-28306977-C-T p.Leu499Leu synonymous ADAMTS5 1 82798 1.20776E-5 41399 0 1.19474E-5
21-28306993-G-A p.Thr494Ile missense ADAMTS5 3 82836 3.62161E-5 41418 0 3.18451E-5
21-28306997-C-G p.Ala493Pro missense ADAMTS5 2 82860 2.41371E-5 41430 0 1.59284E-5
21-28307000-C-T p.Asp492Asn missense ADAMTS5 7 82876 8.44635E-5 41438 0 0.00125
21-28307024-C-T p.Glu484Lys missense ADAMTS5 2 82934 2.41156E-5 41467 0 4.12058E-5
21-28307025-G-A p.Pro483Pro synonymous ADAMTS5 7 82928 8.44106E-5 41464 0 3.29658E-5
21-28307044-C-T p.Arg477Gln missense ADAMTS5 4 82982 4.82032E-5 41491 0 3.18492E-5
21-28315691-A-G c.1405+8T>C splice_region ADAMTS5 1 82708 1.20907E-5 41354 0 NA
21-28315699-C-T p.Gly469Ser missense+splice_region ADAMTS5 1 82802 1.2077E-5 41401 0 NA
21-28315708-C-T p.Asp466Asn missense ADAMTS5 2 82892 2.41278E-5 41446 0 NA
21-28315751-G-T p.Pro451Pro synonymous ADAMTS5 1 83072 1.20378E-5 41536 0 8.32265E-6
21-28315754-C-T p.Lys450Lys synonymous ADAMTS5 9 83034 1.08389E-4 41517 0 2.42102E-4
21-28315761-G-A p.Ala448Val missense ADAMTS5 434 83066 0.00522476 41533 6 0.0108287
21-28315764-T-A p.Asp447Val missense ADAMTS5 1 83082 1.20363E-5 41541 0 6.25E-4
21-28315767-A-G p.Ile446Thr missense ADAMTS5 6 83084 7.22161E-5 41542 0 0.00100705
21-28315790-T-C p.Leu438Leu synonymous ADAMTS5 1 83108 1.20325E-5 41554 0 NA
21-28315794-C-T p.Arg437His missense ADAMTS5 1 83116 1.20314E-5 41558 0 3.18471E-5
21-28315795-G-A p.Arg437Cys missense ADAMTS5 1 83122 1.20305E-5 41561 0 0.00100705
21-28315801-C-A p.Asp435Tyr missense ADAMTS5 1 83134 1.20288E-5 41567 0 NA
21-28315817-G-A p.Thr429Thr synonymous ADAMTS5 1 83116 1.20314E-5 41558 0 NA
21-28315822-C-T p.Glu428Lys missense ADAMTS5 1 83098 1.2034E-5 41549 0 NA
21-28315841-G-A p.Asp421Asp synonymous ADAMTS5 2073 83064 0.0249567 41532 100 0.0417925
21-28315852-G-A p.Leu418Phe missense ADAMTS5 1 83080 1.20366E-5 41540 0 NA
21-28315863-T-C p.His414Arg missense ADAMTS5 1 83048 1.20412E-5 41524 0 2.54777E-4
21-28327058-C-G p.Gly413Arg missense+splice_region ADAMTS5 1 83180 1.20221E-5 41590 0 1.65022E-5
21-28327064-C-T p.Glu411Lys missense ADAMTS5 2 83210 2.40356E-5 41605 0 6.3674E-5
21-28327082-C-T p.Ala405Thr missense ADAMTS5 1 83204 1.20187E-5 41602 0 8.24212E-6
21-28327084-G-C p.Ala404Gly missense ADAMTS5 1 83204 1.20187E-5 41602 0 NA
21-28327085-C-T p.Ala404Thr missense ADAMTS5 1 83200 1.20192E-5 41600 0 1.64845E-5
21-28327086-G-A p.His403His synonymous ADAMTS5 1 83202 1.20189E-5 41601 0 1.64834E-5
21-28327087-T-G p.His403Pro missense ADAMTS5 1 83208 1.20181E-5 41604 0 NA
21-28327093-C-A p.Gly401Val missense ADAMTS5 1 83192 1.20204E-5 41596 0 NA
21-28327095-A-G p.Asp400Asp synonymous ADAMTS5 39 83194 4.68784E-4 41597 0 2.8664E-4
21-28327098-G-A p.Asp399Asp synonymous ADAMTS5 5 83194 6.01005E-5 41597 0 3.1839E-5
21-28327106-T-A p.Ile397Phe missense ADAMTS5 1 83212 1.20175E-5 41606 0 3.18471E-5
21-28327108-A-G p.Val396Ala missense ADAMTS5 9 83222 1.08144E-4 41611 0 4.12045E-5
21-28327120-C-T p.Arg392His missense ADAMTS5 8 83206 9.61469E-5 41603 0 2.786E-5
21-28327121-G-A p.Arg392Cys missense ADAMTS5 8 83214 9.61377E-5 41607 0 6.36821E-5
21-28327127-G-C p.Pro390Ala missense ADAMTS5 1 83220 1.20163E-5 41610 0 NA
21-28327130-A-G p.Ser389Pro missense ADAMTS5 1 83220 1.20163E-5 41610 0 3.97991E-6
21-28327137-G-A p.Thr386Thr synonymous ADAMTS5 2 83240 2.40269E-5 41620 0 NA
21-28327143-A-G p.Val384Val synonymous ADAMTS5 2 83232 2.40292E-5 41616 0 3.18512E-5
21-28327144-A-G p.Val384Ala missense ADAMTS5 1 83230 1.20149E-5 41615 0 3.97975E-6
21-28327145-C-T p.Val384Ile missense ADAMTS5 1 83230 1.20149E-5 41615 0 2.47627E-5
21-28327145-C-G p.Val384Leu missense ADAMTS5 1 83230 1.20149E-5 41615 0 NA
21-28327146-G-A p.Asp383Asp synonymous ADAMTS5 1 83228 1.20152E-5 41614 0 3.98004E-6
21-28327171-G-C p.Ser375* stop_gained ADAMTS5 1 83196 1.20198E-5 41598 0 3.98187E-6
21-28327175-G-A p.His374Tyr missense ADAMTS5 2 83188 2.40419E-5 41594 0 NA
21-28327179-C-T p.Gly372Gly synonymous ADAMTS5 5 83180 6.01106E-5 41590 0 1.91168E-4
21-28337607-C-A p.Glu368Asp missense+splice_region ADAMTS5 1 82614 1.21045E-5 41307 0 NA
21-28337609-C-T p.Glu368Lys missense+splice_region ADAMTS5 3 82652 3.62968E-5 41326 0 6.36862E-5
21-28337611-C-T p.Arg367Gln missense ADAMTS5 1 82662 1.20975E-5 41331 0 8.58457E-6
21-28337671-T-C p.Gln347Arg missense ADAMTS5 1 83218 1.20166E-5 41609 0 NA
21-28337676-C-T p.Gln345Gln synonymous ADAMTS5 1 83220 1.20163E-5 41610 0 NA
21-28337691-G-A p.Asn340Asn synonymous ADAMTS5 1 83242 1.20132E-5 41621 0 2.47158E-5
21-28337701-G-A p.Thr337Ile missense ADAMTS5 3 83234 3.6043E-5 41617 0 1.64756E-5
21-28337705-T-C p.Thr336Ala missense ADAMTS5 2 83228 2.40304E-5 41614 0 6.36862E-5
21-28337708-C-T p.Ala335Thr missense ADAMTS5 2 83214 2.40344E-5 41607 0 NA
21-28337719-C-G p.Ser331Thr missense ADAMTS5 1 83226 1.20155E-5 41613 0 NA
21-28337721-C-T p.Val330Val synonymous ADAMTS5 2 83230 2.40298E-5 41615 0 3.18329E-5
21-28337723-C-T p.Val330Met missense ADAMTS5 2 83228 2.40304E-5 41614 0 5.03525E-4
21-28337725-T-G p.Glu329Ala missense ADAMTS5 2 83230 2.40298E-5 41615 0 8.2371E-6
21-28337726-C-T p.Glu329Lys missense ADAMTS5 14 83234 1.682E-4 41617 0 1.23556E-4
21-28337731-C-T p.Ser327Asn missense ADAMTS5 1 83226 1.20155E-5 41613 0 3.97652E-6
21-28337732-T-C p.Ser327Gly missense ADAMTS5 1 83220 1.20163E-5 41610 0 3.97646E-6
21-28337736-G-C p.Asp325Glu missense ADAMTS5 1 83208 1.20181E-5 41604 0 1.64747E-5
21-28337757-C-G p.Val318Val synonymous ADAMTS5 1 83080 1.20366E-5 41540 0 NA
21-28337769-G-C p.Ala314Ala synonymous ADAMTS5 41 82964 4.9419E-4 41482 0 2.71882E-4
21-28337776-C-A p.Arg312Leu missense ADAMTS5 13 82872 1.56868E-4 41436 0 6.25E-4
21-28337783-G-A p.His310Tyr missense ADAMTS5 676 82782 0.00816603 41391 15 0.0176103
21-28337789-C-G p.Glu308Gln missense ADAMTS5 3 82664 3.62915E-5 41332 0 3.97839E-6
21-28337795-T-C p.Ser306Gly missense ADAMTS5 2 82504 2.42412E-5 41252 0 NA
21-28337807-AC-A p.Tyr302fs frameshift ADAMTS5 1 82092 1.21815E-5 41046 0 NA
21-28337819-C-A p.Ala298Ser missense ADAMTS5 1 81360 1.22911E-5 40680 0 NA
21-28337821-A-T p.Ile297Asn missense ADAMTS5 1 81258 1.23065E-5 40629 0 3.98575E-6
21-28337828-C-T p.Ala295Thr missense ADAMTS5 4 80760 4.95295E-5 40380 0 1.71648E-4
21-28337833-G-T p.Thr293Asn missense ADAMTS5 2 80318 2.4901E-5 40159 0 NA
21-28337840-G-A p.Leu291Leu synonymous ADAMTS5 29 79574 3.64441E-4 39787 1 0.00151057
21-28337859-G-A p.Gly284Gly synonymous ADAMTS5 210 76416 0.00274812 38208 0 0.00541298
21-28337867-A-G p.Leu282Leu synonymous ADAMTS5 1 75316 1.32774E-5 37658 0 NA
21-28337869-C-T p.Arg281Gln missense ADAMTS5 2 74932 2.66909E-5 37466 0 3.18451E-5
21-28337870-G-A p.Arg281Trp missense ADAMTS5 6 74458 8.05823E-5 37229 0 6.36943E-5
21-28337871-C-A p.Ala280Ala synonymous ADAMTS5 54 74250 7.27273E-4 37125 0 0.00270666
21-28337900-G-A p.Leu271Leu synonymous ADAMTS5 1 68264 1.4649E-5 34132 0 NA
21-28337905-A-G p.Val269Ala missense ADAMTS5 1 67174 1.48867E-5 33587 0 4.53793E-5
21-28337911-C-T p.Arg267His missense ADAMTS5 1 65594 1.52453E-5 32797 0 8.83869E-5
21-28337912-G-T p.Arg267Ser missense ADAMTS5 5 65536 7.62939E-5 32768 0 2.79228E-4
21-28337913-G-C p.Ala266Ala synonymous ADAMTS5 1 65322 1.53088E-5 32661 0 NA
21-28337918-G-A p.Arg265Trp missense ADAMTS5 2 64422 3.10453E-5 32211 0 4.48234E-6
21-28337928-G-T p.Arg261Arg synonymous ADAMTS5 6 62224 9.64258E-5 31112 0 3.23421E-5
21-28337934-C-G p.Arg259Arg synonymous ADAMTS5 1 60840 1.64366E-5 30420 0 1.91144E-4
21-28337937-C-A p.Arg258Arg synonymous ADAMTS5 1 60574 1.65087E-5 30287 0 9.41868E-6
21-28337942-G-A p.Arg257Trp missense ADAMTS5 2 59980 3.33444E-5 29990 0 4.69885E-6
21-28337942-G-T p.Arg257Arg synonymous ADAMTS5 2 59980 3.33444E-5 29990 0 NA
21-28337948-A-G p.Trp255Arg missense ADAMTS5 1 60068 1.66478E-5 30034 0 4.64152E-5
21-28337949-C-A p.Thr254Thr synonymous ADAMTS5 1 59962 1.66772E-5 29981 0 3.12451E-5
21-28337961-T-G p.Ser250Ser synonymous ADAMTS5 24 59052 4.06421E-4 29526 0 0.00457317
21-28337964-G-T p.Gly249Gly synonymous ADAMTS5 1 58504 1.70928E-5 29252 0 1.68936E-5
21-28337964-G-C p.Gly249Gly synonymous ADAMTS5 1 58504 1.70928E-5 29252 0 NA
21-28337965-C-T p.Gly249Asp missense ADAMTS5 2 58486 3.41962E-5 29243 0 3.38696E-5
21-28337973-G-A p.Pro246Pro synonymous ADAMTS5 2 57828 3.45853E-5 28914 0 1.47511E-5
21-28337973-G-T p.Pro246Pro synonymous ADAMTS5 1 57826 1.72933E-5 28913 0 3.18634E-5
21-28337979-G-C p.Leu244Leu synonymous ADAMTS5 1 57776 1.73082E-5 28888 0 NA
21-28337981-G-A p.Leu244Phe missense ADAMTS5 411 57652 0.00712898 28826 12 0.0194367
21-28337990-G-T p.Gln241Lys missense ADAMTS5 2 57178 3.49785E-5 28589 0 1.53659E-5
21-28337991-G-T p.Asp240Glu missense ADAMTS5 8 57206 1.39845E-4 28603 0 0.001875
21-28337996-A-G p.Leu239Leu synonymous ADAMTS5 1 57266 1.74624E-5 28633 0 NA
21-28338000-C-T p.Gln237Gln synonymous ADAMTS5 1 57162 1.74941E-5 28581 0 5.27398E-6
21-28338002-G-T p.Gln237Lys missense ADAMTS5 1 56942 1.75617E-5 28471 0 NA
21-28338024-G-T p.Ser229Arg missense ADAMTS5 3 58022 5.17045E-5 29011 0 NA
21-28338028-G-C p.Pro228Arg missense ADAMTS5 1 58916 1.69733E-5 29458 0 5.09165E-4
21-28338031-T-A p.Asn227Ile missense ADAMTS5 11 59638 1.84446E-4 29819 0 1.57878E-4
21-28338036-G-A p.His225His synonymous ADAMTS5 1 60212 1.6608E-5 30106 0 NA
21-28338038-G-A p.His225Tyr missense ADAMTS5 2 60154 3.3248E-5 30077 0 NA
21-28338039-C-T p.Ala224Ala synonymous ADAMTS5 10 60080 1.66445E-4 30040 0 0.00180505
21-28338041-C-T p.Ala224Thr missense ADAMTS5 2 60396 3.31148E-5 30198 0 8.80592E-5
21-28338042-C-T p.Pro223Pro synonymous ADAMTS5 2 60618 3.29935E-5 30309 0 2.54331E-5
21-28338044-G-A p.Pro223Ser missense ADAMTS5 1 61232 1.63313E-5 30616 0 3.18512E-5
21-28338045-A-T p.Ala222Ala synonymous ADAMTS5 68 61296 0.00110937 30648 0 0.00815494
21-28338053-C-T p.Glu220Lys missense ADAMTS5 2 62410 3.20461E-5 31205 0 NA
21-28338057-G-A p.Ala218Ala synonymous ADAMTS5 3 62992 4.76251E-5 31496 0 2.86789E-4
21-28338065-G-A p.Pro216Ser missense ADAMTS5 1 64292 1.5554E-5 32146 0 NA
21-28338067-G-C p.Thr215Arg missense ADAMTS5 1 64464 1.55125E-5 32232 0 NA
21-28338069-G-T p.Ser214Ser synonymous ADAMTS5 1 64688 1.54588E-5 32344 0 NA
21-28338074-C-A p.Ala213Ser missense ADAMTS5 2 65066 3.0738E-5 32533 0 6.37024E-5
21-28338078-G-A p.Thr211Thr synonymous ADAMTS5 1 66134 1.51208E-5 33067 0 4.63293E-6
21-28338084-G-C p.Cys209Trp missense ADAMTS5 1 66688 1.49952E-5 33344 0 5.07614E-4
21-28338089-T-C p.Ser208Gly missense ADAMTS5 1 67876 1.47327E-5 33938 0 NA
21-28338090-G-A p.Ala207Ala synonymous ADAMTS5 1 67912 1.47249E-5 33956 0 6.37146E-5
21-28338095-G-A p.Arg206Cys missense ADAMTS5 2 67884 2.9462E-5 33942 0 0.00152284
21-28338110-C-G p.Glu201Gln missense ADAMTS5 1 71184 1.40481E-5 35592 0 NA
21-28338116-T-C p.Ser199Gly missense ADAMTS5 5 72744 6.87342E-5 36372 0 0.00151822
21-28338120-G-C p.Gly197Gly synonymous ADAMTS5 28 73244 3.82284E-4 36622 0 0.00404858
21-28338122-C-T p.Gly197Ser missense ADAMTS5 2 73692 2.714E-5 36846 0 3.18593E-5
21-28338126-G-C p.Arg195Arg synonymous ADAMTS5 1 73572 1.35921E-5 36786 0 NA
21-28338127-C-T p.Arg195His missense ADAMTS5 2 74016 2.70212E-5 37008 0 NA
21-28338148-C-T p.Arg188Gln missense ADAMTS5 1 77212 1.29514E-5 38606 0 3.18634E-5
21-28338149-G-A p.Arg188Trp missense ADAMTS5 2 77328 2.58639E-5 38664 0 5.06073E-4
21-28338161-C-A p.Asp184Tyr missense ADAMTS5 18 79210 2.27244E-4 39605 0 9.56084E-5
21-28338161-C-T p.Asp184Asn missense ADAMTS5 1 79212 1.26243E-5 39606 0 6.37389E-5
21-28338166-T-C p.Tyr182Cys missense ADAMTS5 3 79700 3.76412E-5 39850 0 8.22883E-6
21-28338195-G-A p.Pro172Pro synonymous ADAMTS5 1 81636 1.22495E-5 40818 0 NA
21-28338203-G-C p.Arg170Gly missense ADAMTS5 1 81776 1.22285E-5 40888 0 6.25E-4
21-28338227-G-T p.Arg162Ser missense ADAMTS5 1 82310 1.21492E-5 41155 0 4.35244E-5
21-28338230-C-T p.Ala161Thr missense ADAMTS5 3 82350 3.64299E-5 41175 0 1.73847E-4
21-28338234-C-T p.Lys159Lys synonymous ADAMTS5 6 82424 7.27943E-5 41212 0 6.25E-4
21-28338255-G-A p.Leu152Leu synonymous ADAMTS5 9 82274 1.09391E-4 41137 0 3.18674E-5
21-28338259-C-A p.Gly151Val missense ADAMTS5 2 82260 2.43132E-5 41130 0 NA
21-28338264-A-C p.Cys149Trp missense ADAMTS5 1 82228 1.21613E-5 41114 0 NA
21-28338269-G-A p.Leu148Phe missense ADAMTS5 1 82132 1.21755E-5 41066 0 1.71374E-5
21-28338281-C-A p.Ala144Ser missense ADAMTS5 1 81920 1.2207E-5 40960 0 NA
21-28338289-C-A p.Arg141Leu missense ADAMTS5 2 81740 2.44678E-5 40870 0 8.56458E-6
21-28338298-C-G p.Gly138Ala missense ADAMTS5 13002 81338 0.159851 40669 1157 0.156681
21-28338299-C-G p.Gly138Arg missense ADAMTS5 3 81510 3.68053E-5 40755 0 5.04032E-4
21-28338307-G-T p.Thr135Lys missense ADAMTS5 228 81472 0.00279851 40736 0 0.00352467
21-28338308-T-A p.Thr135Ser missense ADAMTS5 1 81450 1.22775E-5 40725 0 NA
21-28338313-C-G p.Arg133Pro missense ADAMTS5 2 81418 2.45646E-5 40709 0 NA
21-28338313-C-T p.Arg133Gln missense ADAMTS5 1 81418 1.22823E-5 40709 0 4.26694E-5
21-28338314-G-T p.Arg133Arg synonymous ADAMTS5 35 81400 4.29975E-4 40700 0 0.00251762
21-28338314-G-A p.Arg133Trp missense ADAMTS5 6 81400 7.37101E-5 40700 0 6.82722E-5
21-28338336-G-A p.Arg125Arg synonymous ADAMTS5 6 80852 7.42097E-5 40426 0 6.0024E-5
21-28338338-G-T p.Arg125Ser missense ADAMTS5 5 80838 6.18521E-5 40419 0 8.57236E-5
21-28338345-C-A p.Ala122Ala synonymous ADAMTS5 5 80740 6.19272E-5 40370 0 0.00302115
21-28338346-G-A p.Ala122Val missense ADAMTS5 1 80712 1.23897E-5 40356 0 NA
21-28338346-G-T p.Ala122Glu missense ADAMTS5 2 80712 2.47795E-5 40356 0 4.04102E-6
21-28338348-A-C p.Ser121Arg missense ADAMTS5 7 80690 8.67518E-5 40345 0 2.55395E-4
21-28338351-C-T p.Thr120Thr synonymous ADAMTS5 2 80810 2.47494E-5 40405 0 3.18776E-5
21-28338365-C-T p.Ala116Thr missense ADAMTS5 1 80816 1.23738E-5 40408 0 8.54248E-6
21-28338378-A-G p.Ala111Ala synonymous ADAMTS5 2 80866 2.47323E-5 40433 0 2.23115E-4
21-28338380-C-T p.Ala111Thr missense ADAMTS5 3 80878 3.70929E-5 40439 0 NA
21-28338381-A-C p.Ile110Met missense ADAMTS5 2 80888 2.47255E-5 40444 0 NA
21-28338388-A-G p.Val108Ala missense ADAMTS5 1 80820 1.23732E-5 40410 0 4.02658E-6
21-28338397-T-A p.Asp105Val missense ADAMTS5 10 80680 1.23946E-4 40340 0 5.03525E-4
21-28338400-C-T p.Arg104Gln missense ADAMTS5 2 80762 2.47641E-5 40381 0 4.0333E-6
21-28338405-C-T p.Leu102Leu synonymous ADAMTS5 1 80726 1.23876E-5 40363 0 NA
21-28338408-G-A p.Asp101Asp synonymous ADAMTS5 15 80716 1.85837E-4 40358 0 0.00125
21-28338411-C-A p.Leu100Phe missense ADAMTS5 1 80716 1.23891E-5 40358 0 NA
21-28338417-G-T p.Phe98Leu missense ADAMTS5 1 80520 1.24193E-5 40260 0 1.59266E-4
21-28338421-CTC-TTG p.ArgArg96ArgLys missense ADAMTS5 1 80406 1.24369E-5 40203 0 NA
21-28338423-C-G p.Arg96Arg synonymous ADAMTS5 13114 79442 0.165076 39721 1076 0.184716
21-28338425-G-A p.Arg96Trp missense ADAMTS5 1655 80160 0.0206462 40080 13 0.019375
21-28338425-G-C p.Arg96Gly missense ADAMTS5 2 80238 2.49258E-5 40119 0 3.18756E-5
21-28338427-C-T p.Gly95Asp missense ADAMTS5 1 80170 1.24735E-5 40085 0 NA
21-28338429-G-T p.Gly94Gly synonymous ADAMTS5 3 80098 3.74541E-5 40049 0 3.18776E-5
21-28338440-C-A p.Val91Phe missense ADAMTS5 2 79888 2.5035E-5 39944 0 8.66386E-6
21-28338441-G-A p.Leu90Leu synonymous ADAMTS5 2 79796 2.50639E-5 39898 0 9.56023E-5
21-28338441-G-T p.Leu90Leu synonymous ADAMTS5 1 79796 1.2532E-5 39898 0 8.66536E-6
21-28338448-C-T p.Gly88Asp missense ADAMTS5 4 79452 5.03449E-5 39726 0 4.36133E-5
21-28338449-C-A p.Gly88Cys missense ADAMTS5 3 79414 3.77767E-5 39707 0 9.56206E-5
21-28338450-C-T p.Val87Val synonymous ADAMTS5 1 79406 1.25935E-5 39703 0 5.03525E-4
21-28338451-A-T p.Val87Glu missense ADAMTS5 5 79272 6.3074E-5 39636 0 1.26586E-4
21-28338457-CC-AA p.Gly85Phe missense ADAMTS5 10 78860 1.26807E-4 39430 0 NA
21-28338458-C-A p.Gly85Cys missense ADAMTS5 2 78770 2.53904E-5 39385 0 3.6811E-5
21-28338474-T-C p.Gln79Gln synonymous ADAMTS5 5 77348 6.46429E-5 38674 0 2.66709E-5
21-28338488-G-C p.Gln75Glu missense ADAMTS5 10 75086 1.33181E-4 37543 0 6.32223E-5
21-28338494-G-A p.Leu73Leu synonymous ADAMTS5 1 74062 1.35022E-5 37031 0 9.03685E-6
21-28338498-C-A p.Lys71Asn missense ADAMTS5 14 73320 1.90944E-4 36660 0 1.27413E-4
21-28338508-C-T p.Arg68His missense ADAMTS5 1 70728 1.41387E-5 35364 0 NA
21-28338511-C-A p.Arg67Leu missense ADAMTS5 5 70032 7.13959E-5 35016 0 5.04032E-4
21-28338517-G-T p.Ala65Glu missense ADAMTS5 1 68960 1.45012E-5 34480 0 8.93935E-6
21-28338522-G-T p.Pro63Pro synonymous ADAMTS5 1 68770 1.45412E-5 34385 0 4.46684E-5
21-28338524-G-T p.Pro63Thr missense ADAMTS5 6 68406 8.77116E-5 34203 0 1.1458E-4
21-28338525-G-T p.His62Gln missense ADAMTS5 4 68328 5.85412E-5 34164 0 9.54891E-6
21-28338526-T-C p.His62Arg missense ADAMTS5 14 68026 2.05804E-4 34013 0 1.27845E-4
21-28338529-G-C p.Pro61Arg missense ADAMTS5 19 67410 2.81857E-4 33705 0 0.00151057
21-28338531-G-C p.His60Gln missense ADAMTS5 1 67154 1.48911E-5 33577 0 0.00125
21-28338534-G-A p.Gly59Gly synonymous ADAMTS5 1 66226 1.50998E-5 33113 0 9.8147E-6
21-28338536-C-T p.Gly59Ser missense ADAMTS5 1 65630 1.52369E-5 32815 0 NA
21-28338550-C-T p.Arg54Gln missense ADAMTS5 3 62602 4.79218E-5 31301 0 1.08291E-5
21-28338550-C-A p.Arg54Leu missense ADAMTS5 3 62602 4.79218E-5 31301 0 3.24872E-5
21-28338551-G-T p.Arg54Arg synonymous ADAMTS5 1 62044 1.61176E-5 31022 0 NA
21-28338554-C-A p.Glu53* stop_gained ADAMTS5 2 62094 3.22092E-5 31047 0 NA
21-28338555-C-T p.Gln52Gln synonymous ADAMTS5 2 61944 3.22872E-5 30972 0 9.8871E-4
21-28338560-C-T p.Val51Met missense ADAMTS5 1 60852 1.64333E-5 30426 0 2.42207E-5
21-28338561-C-T p.Glu50Glu synonymous ADAMTS5 35 60736 5.76265E-4 30368 0 4.30935E-4
21-28338561-C-G p.Glu50Asp missense ADAMTS5 3 60742 4.93892E-5 30371 0 2.42371E-5
21-28338569-C-G p.Gly48Arg missense ADAMTS5 1 59676 1.67572E-5 29838 0 3.1902E-5
21-28338574-C-G p.Arg46Pro missense ADAMTS5 1 57878 1.72777E-5 28939 0 NA
21-28338578-G-A p.Arg45Trp missense ADAMTS5 1 57352 1.74362E-5 28676 0 1.01531E-4
21-28338581-G-T p.Arg44Ser missense ADAMTS5 1990 56796 0.0350377 28398 51 0.0791503
21-28338583-G-C p.Pro43Arg missense ADAMTS5 1 56658 1.76498E-5 28329 0 NA
21-28338590-C-A p.Ala41Ser missense ADAMTS5 3 54716 5.48286E-5 27358 0 9.58834E-5
21-28338594-T-G p.Ala39Ala synonymous ADAMTS5 1 54328 1.84067E-5 27164 0 NA
21-28338606-C-G p.Pro35Pro synonymous ADAMTS5 1 51860 1.92827E-5 25930 0 NA
21-28338607-G-A p.Pro35Leu missense ADAMTS5 1 51724 1.93334E-5 25862 0 6.82277E-6
21-28338609-A-C p.Pro34Pro synonymous ADAMTS5 4 51478 7.77031E-5 25739 0 5.17277E-5
21-28338617-C-G p.Gly32Arg missense ADAMTS5 1 49992 2.00032E-5 24996 0 7.63149E-6
21-28338617-C-T p.Gly32Arg missense ADAMTS5 1 49992 2.00032E-5 24996 0 6.39018E-5
21-28338618-G-C p.Ala31Ala synonymous ADAMTS5 4 49956 8.00705E-5 24978 0 5.69152E-4
21-28338627-C-T p.Gln28Gln synonymous ADAMTS5 2 49316 4.05548E-5 24658 0 NA
21-28338647-G-A p.Pro22Ser missense ADAMTS5 3 46978 6.38597E-5 23489 1 0.00114416
21-28338650-C-G p.Gly21Arg missense ADAMTS5 2 46060 4.34216E-5 23030 0 3.19509E-5
21-28338654-C-A p.Ala19Ala synonymous ADAMTS5 2 46046 4.34348E-5 23023 0 1.3957E-4
21-28338665-G-A p.Pro16Ser missense ADAMTS5 1 46260 2.16169E-5 23130 0 NA
21-28338666-C-T p.Leu15Leu synonymous ADAMTS5 1 46014 2.17325E-5 23007 0 NA
21-28338669-G-A p.Arg14Arg synonymous ADAMTS5 3 45810 6.54879E-5 22905 1 2.09026E-5
21-28338678-G-A p.Cys11Cys synonymous ADAMTS5 1 45224 2.21122E-5 22612 0 4.26749E-5
21-28338681-C-T p.Leu10Leu synonymous ADAMTS5 2 45376 4.40762E-5 22688 0 3.19448E-5
21-28338686-G-A p.Leu9Leu synonymous ADAMTS5 2 45284 4.41657E-5 22642 0 6.67097E-5
21-28338687-C-G p.Leu8Leu synonymous ADAMTS5 1 45234 2.21073E-5 22617 0 NA
21-28338692-A-C p.Ser7Ala missense ADAMTS5 2 45004 4.44405E-5 22502 0 NA
21-28338693-C-G p.Ala6Ala synonymous ADAMTS5 3 44872 6.68568E-5 22436 0 3.1953E-5
21-28338697-C-A p.Trp5Leu missense ADAMTS5 1 44956 2.2244E-5 22478 0 NA
21-28338701-C-T p.Gly4Arg missense ADAMTS5 1 44810 2.23164E-5 22405 0 1.42914E-5
21-28338806-C-G c.-96G>C 5_prime_UTR_premature_start_codon_gain ADAMTS5 1 36934 2.70753E-5 18467 0 NA