Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
1-161160935-C-T p.Arg836Lys missense ADAMTS4 17 81436 2.08753E-4 40718 0 3.12338E-4
1-161160940-C-T p.Ala834Ala synonymous ADAMTS4 1 81566 1.226E-5 40783 0 2.4095E-5
1-161160941-G-A p.Ala834Val missense ADAMTS4 4 81572 4.90364E-5 40786 0 1.59246E-4
1-161160941-G-C p.Ala834Gly missense ADAMTS4 4 81572 4.90364E-5 40786 0 5.04032E-4
1-161160951-G-A p.Arg831Cys missense ADAMTS4 2 81854 2.44337E-5 40927 0 6.25E-4
1-161160953-C-T p.Arg830Gln missense ADAMTS4 2 82010 2.43873E-5 41005 0 3.1841E-5
1-161160954-G-A p.Arg830Trp missense ADAMTS4 3 82010 3.65809E-5 41005 0 9.36119E-6
1-161160956-C-T p.Arg829Gln missense ADAMTS4 115 82164 0.00139964 41082 1 0.00108266
1-161160960-G-A p.Leu828Phe missense ADAMTS4 2 82316 2.42966E-5 41158 0 9.23327E-6
1-161160974-T-C p.Gln823Arg missense ADAMTS4 5 82530 6.0584E-5 41265 0 5.04032E-4
1-161160983-C-T p.Arg820Gln missense ADAMTS4 10 82536 1.21159E-4 41268 0 6.69774E-4
1-161160993-A-T p.Trp817Arg missense ADAMTS4 1 82626 1.21027E-5 41313 0 3.18552E-5
1-161160998-T-A p.Gln815Leu missense ADAMTS4 1 82636 1.21013E-5 41318 0 NA
1-161161002-G-T p.Pro814Thr missense ADAMTS4 1 82656 1.20983E-5 41328 0 NA
1-161161003-A-G p.Thr813Thr synonymous ADAMTS4 1 82604 1.2106E-5 41302 0 1.20557E-5
1-161161004-G-A p.Thr813Ile missense ADAMTS4 3 82652 3.62968E-5 41326 0 8.02671E-5
1-161161010-C-T p.Arg811His missense ADAMTS4 2 82622 2.42066E-5 41311 0 8.03E-5
1-161161011-G-A p.Arg811Cys missense ADAMTS4 6 82670 7.25777E-5 41335 1 4.27226E-5
1-161161015-C-T p.Thr809Thr synonymous ADAMTS4 3 82660 3.62932E-5 41330 0 3.60378E-5
1-161161016-G-A p.Thr809Met missense ADAMTS4 136 82726 0.00164398 41363 0 0.0016717
1-161161027-C-T p.Pro805Pro synonymous ADAMTS4 3 82692 3.62792E-5 41346 0 0.001875
1-161161028-G-A p.Pro805Leu missense ADAMTS4 1 82720 1.2089E-5 41360 0 1.03909E-4
1-161161031-C-T p.Arg804Gln missense ADAMTS4 3 82738 3.6259E-5 41369 0 6.37471E-5
1-161161032-G-A p.Arg804Trp missense ADAMTS4 3 82782 3.62398E-5 41391 0 8.38054E-6
1-161161034-G-A p.Pro803Leu missense ADAMTS4 3 82810 3.62275E-5 41405 0 3.18593E-5
1-161161038-C-T p.Val802Met missense ADAMTS4 8 82804 9.66137E-5 41402 0 0.00100806
1-161161039-G-A p.Phe801Phe synonymous ADAMTS4 1 82838 1.20718E-5 41419 0 3.99112E-6
1-161161052-C-T p.Arg797Gln missense ADAMTS4 1 82842 1.20712E-5 41421 0 1.99518E-5
1-161161059-G-A p.Arg795Cys missense ADAMTS4 9 82858 1.0862E-4 41429 0 3.59092E-5
1-161161086-G-C p.Leu786Val missense ADAMTS4 2 82986 2.41005E-5 41493 0 1.65722E-5
1-161161097-G-T p.Thr782Lys missense ADAMTS4 2 82974 2.41039E-5 41487 0 9.93921E-5
1-161161104-G-A p.Pro780Ser missense ADAMTS4 1 82946 1.2056E-5 41473 0 3.98527E-6
1-161161105-C-T p.Gln779Gln synonymous ADAMTS4 1 82946 1.2056E-5 41473 0 NA
1-161161113-G-C p.Leu777Val missense ADAMTS4 1 82926 1.20589E-5 41463 0 1.19599E-5
1-161161116-G-A p.Pro776Ser missense ADAMTS4 1 82894 1.20636E-5 41447 0 4.96936E-5
1-161161153-C-A p.Gly763Gly synonymous ADAMTS4 2 82830 2.41458E-5 41415 0 NA
1-161161155-C-T p.Gly763Arg missense ADAMTS4 1 82826 1.20735E-5 41413 0 NA
1-161161156-G-A p.Ser762Ser synonymous ADAMTS4 1 82818 1.20747E-5 41409 0 4.96829E-5
1-161161164-G-A p.Arg760Cys missense ADAMTS4 2 82772 2.41628E-5 41386 0 0.0015121
1-161161167-A-G p.Leu759Leu synonymous ADAMTS4 1 82784 1.20796E-5 41392 0 NA
1-161161168-G-A p.Ser758Ser synonymous ADAMTS4 7 82790 8.45513E-5 41395 0 9.55353E-5
1-161161170-T-C p.Ser758Gly missense ADAMTS4 7 82814 8.45268E-5 41407 0 7.56942E-5
1-161161175-G-T p.Ala756Glu missense ADAMTS4 3 82810 3.62275E-5 41405 0 NA
1-161161184-A-C p.Leu753Arg missense ADAMTS4 1 82774 1.20811E-5 41387 0 NA
1-161161196-G-A p.Thr749Ile missense ADAMTS4 1 82840 1.20715E-5 41420 0 NA
1-161161201-G-T p.Ser747Ser synonymous ADAMTS4 1 82892 1.20639E-5 41446 0 NA
1-161161204-G-C p.Pro746Pro synonymous ADAMTS4 1 82890 1.20642E-5 41445 0 NA
1-161161206-G-T p.Pro746Thr missense ADAMTS4 3 82880 3.61969E-5 41440 0 NA
1-161161211-A-G p.Leu744Pro missense ADAMTS4 1 82888 1.20645E-5 41444 0 3.18613E-5
1-161161213-C-T p.Thr743Thr synonymous ADAMTS4 1 82868 1.20674E-5 41434 0 2.86843E-4
1-161161214-G-A p.Thr743Met missense ADAMTS4 3 82884 3.61952E-5 41442 0 5.04032E-4
1-161161226-T-C p.Asn739Ser missense ADAMTS4 1 82906 1.20619E-5 41453 0 NA
1-161161240-G-A p.Gly734Gly synonymous ADAMTS4 1 82860 1.20685E-5 41430 0 8.25369E-6
1-161161241-C-A p.Gly734Val missense ADAMTS4 1 82828 1.20732E-5 41414 0 NA
1-161161264-G-A p.Tyr726Tyr synonymous ADAMTS4 2 82698 2.41844E-5 41349 0 8.25668E-6
1-161161274-C-T p.Arg723Gln missense ADAMTS4 2 82436 2.42612E-5 41218 0 5.97633E-5
1-161161275-G-C p.Arg723Gly missense ADAMTS4 2 82402 2.42713E-5 41201 0 1.57056E-4
1-161161283-G-A p.Pro720Leu missense ADAMTS4 1 82234 1.21604E-5 41117 0 7.97232E-6
1-161161284-G-C p.Pro720Ala missense ADAMTS4 6824 81942 0.0832784 40971 321 0.1125
1-161161286-T-A p.Asn719Ile missense ADAMTS4 6 82140 7.3046E-5 41070 0 3.18715E-5
1-161161299-G-A p.Arg715Trp missense ADAMTS4 3 81618 3.67566E-5 40809 0 0.00100705
1-161161322-G-A p.Ala707Val missense ADAMTS4 2 80834 2.47421E-5 40417 0 NA
1-161161324-G-A p.Pro706Pro synonymous ADAMTS4 7 80790 8.66444E-5 40395 0 5.03525E-4
1-161161331-G-C p.Thr704Ser missense ADAMTS4 2 80468 2.48546E-5 40234 0 1.71789E-5
1-161161332-T-C p.Thr704Ala missense ADAMTS4 3 80396 3.73153E-5 40198 0 1.21448E-5
1-161161335-C-A p.Val703Phe missense ADAMTS4 1 80256 1.24601E-5 40128 0 0.00100705
1-161161350-C-T p.Gly698Arg missense ADAMTS4 2 79742 2.50809E-5 39871 0 2.07398E-5
1-161161351-G-A p.Tyr697Tyr synonymous ADAMTS4 38 79714 4.76704E-4 39857 0 0.001466
1-161161361-G-A c.2088-7C>T splice_region ADAMTS4 2 79440 2.51762E-5 39720 0 3.82708E-5
1-161161865-T-C p.Arg693Gly missense ADAMTS4 1 80022 1.24966E-5 40011 0 NA
1-161161872-G-T p.Gly690Gly synonymous ADAMTS4 1 80772 1.23805E-5 40386 0 NA
1-161161893-A-G p.Ser683Ser synonymous ADAMTS4 1 82234 1.21604E-5 41117 0 NA
1-161161898-C-T p.Gly682Ser missense ADAMTS4 2 82392 2.42742E-5 41196 0 5.97481E-5
1-161161899-G-A p.Asp681Asp synonymous ADAMTS4 5 82450 6.06428E-5 41225 0 5.03525E-4
1-161161899-G-T p.Asp681Glu missense ADAMTS4 3 82450 3.63857E-5 41225 0 3.98349E-6
1-161161902-C-T p.Gly680Gly synonymous ADAMTS4 2 82576 2.42201E-5 41288 0 3.31411E-5
1-161161903-C-G p.Gly680Ala missense ADAMTS4 2 82614 2.4209E-5 41307 0 NA
1-161161907-C-T p.Gly679Arg missense ADAMTS4 1 82718 1.20893E-5 41359 0 8.2802E-6
1-161161908-G-A p.Cys678Cys synonymous ADAMTS4 10 82724 1.20884E-4 41362 0 1.73858E-4
1-161161914-CATGCACT-C p.Lys674fs frameshift ADAMTS4 1 82918 1.20601E-5 41459 0 NA
1-161161916-T-C p.Met676Val missense ADAMTS4 3 82958 3.61629E-5 41479 0 9.55718E-5
1-161161922-T-C p.Lys674Glu missense ADAMTS4 1 82982 1.20508E-5 41491 0 NA
1-161161941-G-A p.Gly667Gly synonymous ADAMTS4 1 83074 1.20375E-5 41537 0 3.97716E-6
1-161161942-C-T p.Gly667Asp missense ADAMTS4 1 83060 1.20395E-5 41530 0 NA
1-161161943-C-T p.Gly667Ser missense ADAMTS4 2 83076 2.40743E-5 41538 1 NA
1-161161952-G-A p.Arg664Cys missense ADAMTS4 3 83116 3.60941E-5 41558 0 6.76073E-5
1-161161969-A-G p.Ile658Thr missense ADAMTS4 1 83138 1.20282E-5 41569 0 NA
1-161161991-C-G p.Val651Leu missense ADAMTS4 1 83174 1.2023E-5 41587 0 3.97788E-6
1-161161993-G-A p.Ser650Leu missense ADAMTS4 1 83168 1.20239E-5 41584 0 1.65082E-5
1-161161999-C-G p.Ser648Thr missense ADAMTS4 1 83168 1.20239E-5 41584 0 6.25E-4
1-161162004-C-T p.Pro646Pro synonymous ADAMTS4 1 83118 1.20311E-5 41559 0 3.9814E-5
1-161162005-G-A p.Pro646Leu missense ADAMTS4 1 83146 1.2027E-5 41573 0 7.9661E-6
1-161162008-G-A p.Ser645Phe missense ADAMTS4 1 83136 1.20285E-5 41568 0 NA
1-161162019-C-T p.Gly641Gly synonymous ADAMTS4 2 83006 2.40946E-5 41503 0 8.28089E-6
1-161162020-C-A p.Gly641Val missense ADAMTS4 1 82990 1.20496E-5 41495 0 NA
1-161162997-C-A c.1911+6G>T splice_region ADAMTS4 1 81032 1.23408E-5 40516 0 9.55365E-6
1-161163004-C-T p.Arg637Gln missense+splice_region ADAMTS4 4 81342 4.91751E-5 40671 0 5.04032E-4
1-161163021-G-A p.Tyr631Tyr synonymous ADAMTS4 37 81918 4.51671E-4 40959 0 0.0024881
1-161163034-G-A p.Ala627Val missense ADAMTS4 1 82108 1.21791E-5 41054 0 NA
1-161163035-C-T p.Ala627Thr missense ADAMTS4 3 82092 3.65444E-5 41046 0 3.99262E-6
1-161163037-T-C p.Gln626Arg missense ADAMTS4 49283 79978 0.616207 39989 15309 0.677923
1-161163037-TG-CA p.Gln626Trp missense ADAMTS4 2 82106 2.43588E-5 41053 0 NA
1-161163038-G-A p.Gln626* stop_gained ADAMTS4 1 82136 1.21749E-5 41068 0 9.12545E-5
1-161163042-C-G p.Gln624His missense ADAMTS4 1 82212 1.21637E-5 41106 0 NA
1-161163063-G-A p.Asp617Asp synonymous ADAMTS4 1 82382 1.21386E-5 41191 0 NA
1-161163067-T-TG p.Gln616fs frameshift ADAMTS4 2 82406 2.42701E-5 41203 0 NA
1-161163073-G-A p.Ala614Val missense ADAMTS4 1 82500 1.21212E-5 41250 0 NA
1-161163075-C-T p.Val613Val synonymous ADAMTS4 3 82504 3.63619E-5 41252 0 7.96508E-6
1-161163078-G-A p.Gly612Gly synonymous ADAMTS4 3 82520 3.63548E-5 41260 0 8.27253E-6
1-161163088-C-T p.Arg609His missense ADAMTS4 13 82650 1.5729E-4 41325 0 1.276E-4
1-161163089-G-A p.Arg609Cys missense ADAMTS4 9 82662 1.08877E-4 41331 0 0.00100806
1-161163098-A-T p.Trp606Arg missense ADAMTS4 1 82704 1.20913E-5 41352 0 3.18939E-5
1-161163103-A-C p.Met604Arg missense ADAMTS4 1 82748 1.20849E-5 41374 0 NA
1-161163108-C-T p.Gly602Gly synonymous ADAMTS4 6 82744 7.25128E-5 41372 0 0.00302725
1-161163121-T-C p.Lys598Arg missense ADAMTS4 1 82810 1.20758E-5 41405 0 1.65186E-5
1-161163132-G-A p.Thr594Thr synonymous ADAMTS4 1 82814 1.20753E-5 41407 0 1.99079E-5
1-161163135-G-A p.Arg593Arg synonymous ADAMTS4 2 82838 2.41435E-5 41419 0 1.65221E-5
1-161163136-C-T p.Arg593His missense ADAMTS4 1 82802 1.2077E-5 41401 0 3.19122E-5
1-161163137-G-A p.Arg593Cys missense ADAMTS4 1 82788 1.2079E-5 41394 0 3.19183E-5
1-161163144-G-A p.Tyr590Tyr synonymous ADAMTS4 2 82738 2.41727E-5 41369 0 3.19061E-5
1-161163164-C-T p.Glu584Lys missense ADAMTS4 7 82472 8.48773E-5 41236 0 6.38284E-5
1-161163165-G-C p.Arg583Arg synonymous ADAMTS4 62 82416 7.52281E-4 41208 0 5.74493E-4
1-161163165-G-A p.Arg583Arg synonymous ADAMTS4 5 82418 6.06664E-5 41209 0 5.07099E-4
1-161163166-C-T p.Arg583His missense ADAMTS4 2 82390 2.42748E-5 41195 0 2.79533E-5
1-161163167-G-A p.Arg583Cys missense ADAMTS4 1 82376 1.21395E-5 41188 0 8.30924E-6
1-161163185-G-C c.1736-7C>G splice_region ADAMTS4 1 81972 1.21993E-5 40986 0 NA
1-161163439-T-C p.Thr576Ala missense ADAMTS4 265 82702 0.00320428 41351 4 0.0125881
1-161163456-T-C p.Asn570Ser missense ADAMTS4 7 82792 8.45492E-5 41396 0 2.23186E-4
1-161163462-GA-G p.Ser568fs frameshift ADAMTS4 1 82870 1.20671E-5 41435 0 NA
1-161163465-C-T p.Arg567His missense ADAMTS4 4 82882 4.82614E-5 41441 0 9.20471E-5
1-161163465-C-A p.Arg567Leu missense ADAMTS4 1 82882 1.20653E-5 41441 0 NA
1-161163466-G-A p.Arg567Cys missense ADAMTS4 183 82940 0.00220641 41470 0 0.00567602
1-161163471-C-T p.Arg565His missense ADAMTS4 1 82954 1.20549E-5 41477 0 1.20096E-5
1-161163472-G-T p.Arg565Ser missense ADAMTS4 1 82990 1.20496E-5 41495 0 8.31573E-6
1-161163472-G-C p.Arg565Gly missense ADAMTS4 1 82990 1.20496E-5 41495 0 NA
1-161163477-C-T p.Arg563His missense ADAMTS4 22 82978 2.65131E-4 41489 0 3.509E-4
1-161163478-G-A p.Arg563Cys missense ADAMTS4 1 82984 1.20505E-5 41492 0 NA
1-161163480-C-T p.Arg562His missense ADAMTS4 2 82966 2.41063E-5 41483 0 6.38284E-5
1-161163481-G-A p.Arg562Cys missense ADAMTS4 14 83004 1.68667E-4 41502 0 6.38284E-5
1-161163507-C-T p.Arg553Gln missense ADAMTS4 1 83042 1.20421E-5 41521 0 2.47868E-5
1-161163509-G-A p.Pro552Pro synonymous ADAMTS4 1 83070 1.2038E-5 41535 0 3.9853E-6
1-161163514-C-G p.Val551Leu missense ADAMTS4 3 83080 3.61098E-5 41540 0 1.65224E-4
1-161163519-C-A p.Arg549Met missense ADAMTS4 1 83078 1.20369E-5 41539 0 NA
1-161163529-C-T p.Asp546Asn missense ADAMTS4 1 83084 1.2036E-5 41542 0 NA
1-161163531-C-T p.Arg545Gln missense ADAMTS4 2 83078 2.40738E-5 41539 0 3.19224E-5
1-161163531-C-A p.Arg545Leu missense ADAMTS4 1 83078 1.20369E-5 41539 0 NA
1-161163532-G-A p.Arg545* stop_gained ADAMTS4 1 83082 1.20363E-5 41541 0 3.98724E-6
1-161163539-G-A p.Phe542Phe synonymous ADAMTS4 10 83092 1.20349E-4 41546 0 9.56816E-5
1-161163546-AC-A p.Val540fs frameshift ADAMTS4 1 83050 1.20409E-5 41525 0 3.19448E-5
1-161163552-C-T p.Gly538Asp missense ADAMTS4 1 83096 1.20343E-5 41548 0 NA
1-161163560-G-A p.Thr535Thr synonymous ADAMTS4 1 83110 1.20322E-5 41555 0 NA
1-161163564-C-T p.Arg534Gln missense ADAMTS4 3 83096 3.61028E-5 41548 0 2.50522E-5
1-161163577-C-T p.Gly530Ser missense ADAMTS4 1 83082 1.20363E-5 41541 0 8.05938E-6
1-161163578-C-G p.Trp529Cys missense ADAMTS4 2 83082 2.40726E-5 41541 0 8.42545E-6
1-161163597-C-T p.Trp523* stop_gained ADAMTS4 4 83094 4.81383E-5 41547 0 8.52777E-6
1-161163620-CA-C c.1549-5delT splice_region ADAMTS4 1 83110 1.20322E-5 41555 0 NA
1-161163718-A-C c.1548+7T>G splice_region ADAMTS4 1 82222 1.21622E-5 41111 0 9.12392E-6
1-161163726-T-C p.Asn516Ser missense+splice_region ADAMTS4 3 82248 3.64751E-5 41124 0 9.14244E-5
1-161163731-G-A p.Asp514Asp synonymous ADAMTS4 1 82262 1.21563E-5 41131 0 1.82612E-5
1-161163754-G-A p.Leu507Phe missense ADAMTS4 9 82494 1.09099E-4 41247 0 1.70584E-4
1-161163759-C-T p.Arg505His missense ADAMTS4 12 82424 1.45589E-4 41212 0 5.03525E-4
1-161163760-G-A p.Arg505Cys missense ADAMTS4 1 82454 1.2128E-5 41227 0 2.67046E-5
1-161163769-T-C p.Met502Val missense ADAMTS4 3 82488 3.63689E-5 41244 0 5.03525E-4
1-161163782-G-A p.Pro497Pro synonymous ADAMTS4 1 82578 1.21098E-5 41289 0 5.17661E-5
1-161163786-C-G p.Gly496Ala missense ADAMTS4 20 82568 2.42225E-4 41284 0 2.23129E-4
1-161163787-C-T p.Gly496Arg missense ADAMTS4 4 82596 4.84285E-5 41298 0 6.37389E-5
1-161163788-G-A p.Cys495Cys synonymous ADAMTS4 477 82528 0.00577986 41264 7 0.01875
1-161163803-G-A p.Ala490Ala synonymous ADAMTS4 2 82652 2.41978E-5 41326 0 8.39081E-6
1-161163805-C-T p.Ala490Thr missense ADAMTS4 1 82710 1.20904E-5 41355 0 NA
1-161163812-C-A p.Ser487Ser synonymous ADAMTS4 1 82690 1.20934E-5 41345 0 NA
1-161163812-C-T p.Ser487Ser synonymous ADAMTS4 2 82690 2.41867E-5 41345 0 3.18654E-5
1-161163813-G-A p.Ser487Leu missense ADAMTS4 2 82738 2.41727E-5 41369 0 NA
1-161163824-C-G p.Gln483His missense ADAMTS4 1 82780 1.20802E-5 41390 0 NA
1-161163838-G-A p.His479Tyr missense ADAMTS4 1 82802 1.2077E-5 41401 0 3.98708E-6
1-161163846-A-C p.Leu476Arg missense ADAMTS4 1 82846 1.20706E-5 41423 0 NA
1-161163851-G-T p.Gly474Gly synonymous ADAMTS4 13 82868 1.56876E-4 41434 0 1.59286E-4
1-161163878-C-T p.Pro465Pro synonymous ADAMTS4 2 82964 2.41068E-5 41482 0 7.16384E-5
1-161163879-G-A p.Pro465Leu missense ADAMTS4 5 82974 6.02598E-5 41487 0 0.00100705
1-161163882-G-A p.Pro464Leu missense ADAMTS4 4 83010 4.8187E-5 41505 0 1.81848E-4
1-161163890-T-C p.Pro461Pro synonymous ADAMTS4 3 83032 3.61306E-5 41516 0 3.30447E-5
1-161163891-G-A p.Pro461Leu missense ADAMTS4 2 83042 2.40842E-5 41521 0 2.23115E-4
1-161163896-A-G p.His459His synonymous ADAMTS4 1 83038 1.20427E-5 41519 0 3.18613E-5
1-161163900-C-T p.Arg458His missense ADAMTS4 2 83024 2.40894E-5 41512 0 1.98919E-5
1-161163901-G-A p.Arg458Cys missense ADAMTS4 9 83022 1.08405E-4 41511 0 6.37267E-5
1-161163907-C-T p.Asp456Asn missense ADAMTS4 1 82996 1.20488E-5 41498 0 4.12773E-5
1-161163910-G-A p.Pro455Ser missense ADAMTS4 1 82994 1.20491E-5 41497 0 6.3743E-5
1-161163915-A-C p.Phe453Cys missense ADAMTS4 1 82990 1.20496E-5 41495 0 NA
1-161163923-C-T p.Gln450Gln synonymous ADAMTS4 7 82990 8.43475E-5 41495 0 0.001875
1-161163933-C-A p.Arg447Leu missense ADAMTS4 12 82906 1.44742E-4 41453 0 3.18776E-4
1-161163934-G-A p.Arg447Cys missense ADAMTS4 1 82920 1.20598E-5 41460 0 1.59242E-5
1-161163964-T-A p.Thr437Ser missense ADAMTS4 6 82550 7.26832E-5 41275 0 5.03525E-4
1-161163967-C-T p.Val436Met missense ADAMTS4 4 82522 4.84719E-5 41261 0 3.1988E-5
1-161163985-C-T p.Ala430Thr missense ADAMTS4 6 82062 7.31155E-5 41031 0 1.32968E-4
1-161164010-C-T p.Gly421Gly splice_region+synonymous ADAMTS4 2 81158 2.46433E-5 40579 0 8.41978E-6
1-161164015-G-A c.1262-4C>T splice_region ADAMTS4 1 81006 1.23448E-5 40503 0 3.18898E-5
1-161165263-T-C p.Asn418Ser missense ADAMTS4 59 83084 7.10125E-4 41542 0 6.25E-4
1-161165264-T-G p.Asn418His missense ADAMTS4 1 83098 1.2034E-5 41549 0 3.18715E-5
1-161165283-G-T p.Phe411Leu missense ADAMTS4 1 83222 1.20161E-5 41611 0 NA
1-161165288-G-A p.Arg410Cys missense ADAMTS4 4 83208 4.80723E-5 41604 0 6.25E-4
1-161165291-C-A p.Ala409Ser missense ADAMTS4 4 83222 4.80642E-5 41611 0 5.04541E-4
1-161165318-G-C p.Pro400Ala missense ADAMTS4 24 83212 2.8842E-4 41606 0 5.05051E-4
1-161165331-C-T p.Met395Ile missense ADAMTS4 4 83210 4.80711E-5 41605 0 3.18532E-5
1-161165337-A-G p.Pro393Pro synonymous ADAMTS4 1 83196 1.20198E-5 41598 0 1.19427E-5
1-161165340-G-C p.Ala392Ala synonymous ADAMTS4 1 83196 1.20198E-5 41598 0 6.37227E-5
1-161165353-C-T p.Arg388His missense ADAMTS4 14 83144 1.68383E-4 41572 0 1.15471E-4
1-161165354-G-A p.Arg388Cys missense ADAMTS4 10 83156 1.20256E-4 41578 0 1.91253E-4
1-161165369-G-T p.Pro383Thr missense ADAMTS4 2 83112 2.40639E-5 41556 0 1.99151E-5
1-161165413-T-C p.Asn368Ser missense ADAMTS4 1 83048 1.20412E-5 41524 0 4.01258E-6
1-161165414-T-C p.Asn368Asp missense ADAMTS4 1 83042 1.20421E-5 41521 0 NA
1-161165424-A-G p.Gly364Gly splice_region+synonymous ADAMTS4 552 82962 0.00665365 41481 9 0.0137781
1-161165962-C-G p.Leu363Leu splice_region+synonymous ADAMTS4 1 83088 1.20354E-5 41544 0 NA
1-161165963-A-T p.Leu363Gln missense+splice_region ADAMTS4 2 83038 2.40854E-5 41519 0 NA
1-161165968-A-G p.His361His synonymous ADAMTS4 1 83100 1.20337E-5 41550 0 NA
1-161166016-A-G p.Cys345Cys synonymous ADAMTS4 9 83152 1.08236E-4 41576 2 9.57732E-5
1-161166023-C-T p.Arg343Gln missense ADAMTS4 10 83092 1.20349E-4 41546 0 8.28432E-5
1-161166024-G-A p.Arg343Trp missense ADAMTS4 3 83090 3.61054E-5 41545 0 2.48455E-5
1-161166028-C-T p.Pro341Pro synonymous ADAMTS4 3 83102 3.61002E-5 41551 0 9.56999E-5
1-161166029-G-A p.Pro341Leu missense ADAMTS4 45 83108 5.41464E-4 41554 0 7.78171E-4
1-161166039-C-T p.Val338Ile missense ADAMTS4 3 83066 3.61159E-5 41533 0 5.03525E-4
1-161166040-G-A p.Thr337Thr synonymous ADAMTS4 2 83046 2.4083E-5 41523 0 9.5706E-5
1-161166040-G-C p.Thr337Thr synonymous ADAMTS4 1 83046 1.20415E-5 41523 0 8.28446E-6
1-161166045-C-T p.Gly336Ser missense ADAMTS4 2 83072 2.40755E-5 41536 0 NA
1-161166054-C-A p.Ala333Ser missense ADAMTS4 1 83074 1.20375E-5 41537 0 6.25E-4
1-161166057-T-C p.Met332Val missense ADAMTS4 1 83058 1.20398E-5 41529 0 NA
1-161166064-C-T p.Thr329Thr synonymous ADAMTS4 2 82974 2.41039E-5 41487 0 1.1997E-5
1-161166065-G-A p.Thr329Met missense ADAMTS4 1 82972 1.20523E-5 41486 0 3.18817E-5
1-161166069-C-T p.Asp328Asn missense ADAMTS4 1 82926 1.20589E-5 41463 0 3.18837E-5
1-161166070-G-A p.Cys327Cys synonymous ADAMTS4 6 82900 7.23764E-5 41450 0 1.60232E-5
1-161166070-G-C p.Cys327Trp missense ADAMTS4 1 82900 1.20627E-5 41450 0 NA
1-161166295-C-T p.Ala337Thr missense ADAMTS4 1 81882 1.22127E-5 40941 0 8.88415E-6
1-161166316-G-A p.His330Tyr missense ADAMTS4 10 82136 1.21749E-4 41068 0 6.25E-4
1-161166323-C-T p.Gln327Gln synonymous ADAMTS4 1 82228 1.21613E-5 41114 0 NA
1-161166325-G-T p.Gln327Lys missense ADAMTS4 1 82174 1.21693E-5 41087 0 NA
1-161166327-G-A p.Pro326Leu missense ADAMTS4 3 82172 3.65088E-5 41086 0 2.42675E-5
1-161166328-G-A p.Pro326Ser missense ADAMTS4 1 82194 1.21663E-5 41097 0 6.773E-5
1-161166333-G-C p.Ser324* stop_gained ADAMTS4 6 82220 7.29749E-5 41110 0 1.27429E-4
1-161166338-G-C p.Pro322Pro synonymous ADAMTS4 1122 82162 0.0136559 41081 13 0.043125
1-161166359-C-T p.Leu315Leu synonymous ADAMTS4 1 82302 1.21504E-5 41151 0 3.18613E-5
1-161166366-G-C p.Ala313Gly missense ADAMTS4 3 82262 3.64688E-5 41131 0 4.00798E-6
1-161166368-T-C p.Thr312Thr synonymous ADAMTS4 2 82286 2.43055E-5 41143 0 NA
1-161166370-T-C p.Thr312Ala missense ADAMTS4 1 82252 1.21578E-5 41126 0 2.4039E-5
1-161166382-C-G p.Asp308His missense ADAMTS4 12 82248 1.459E-4 41124 0 5.09781E-4
1-161166390-G-A p.Ser305Leu missense ADAMTS4 1 82176 1.2169E-5 41088 0 2.7996E-5
1-161166405-T-C p.Asn300Ser missense ADAMTS4 1 82128 1.21761E-5 41064 0 NA
1-161166410-G-T p.Gly298Gly synonymous ADAMTS4 1 82084 1.21826E-5 41042 0 3.99652E-6
1-161166426-C-T p.Cys293Tyr missense ADAMTS4 1 82188 1.21672E-5 41094 0 NA
1-161166426-C-G p.Cys293Ser missense ADAMTS4 1 82188 1.21672E-5 41094 0 3.18756E-5
1-161166433-T-C p.Ser291Gly missense ADAMTS4 2 82296 2.43025E-5 41148 0 1.64943E-5
1-161166449-A-G p.Ala285Ala synonymous ADAMTS4 2 82430 2.4263E-5 41215 0 4.12521E-5
1-161166455-G-A p.Pro283Pro synonymous ADAMTS4 5 82532 6.05826E-5 41266 0 1.19592E-5
1-161166472-C-G p.Gly278Arg missense ADAMTS4 1 82570 1.21109E-5 41285 0 NA
1-161166476-C-G p.Glu276Asp missense ADAMTS4 1 82666 1.20969E-5 41333 0 NA
1-161166496-C-T p.Val270Met missense ADAMTS4 1 83010 1.20467E-5 41505 0 3.98279E-6
1-161166501-C-T p.Arg268Gln missense ADAMTS4 3 83064 3.61167E-5 41532 0 8.253E-6
1-161166502-G-A p.Arg268Trp missense ADAMTS4 1 83060 1.20395E-5 41530 0 7.96648E-6
1-161166506-C-T p.Val266Val synonymous ADAMTS4 1 83082 1.20363E-5 41541 0 1.59291E-5
1-161166521-A-G p.Pro261Pro synonymous ADAMTS4 1 83186 1.20213E-5 41593 0 8.25382E-6
1-161166549-G-T p.Ala252Asp missense ADAMTS4 1 83196 1.20198E-5 41598 0 7.98155E-6
1-161166550-C-A p.Ala252Ser missense ADAMTS4 7 83192 8.41427E-5 41596 0 2.47713E-5
1-161166563-T-C p.Ala247Ala synonymous ADAMTS4 2 83234 2.40286E-5 41617 0 2.47782E-5
1-161166579-A-G p.Leu242Pro missense ADAMTS4 1 83238 1.20137E-5 41619 0 NA
1-161166581-G-A p.Tyr241Tyr synonymous ADAMTS4 4 83230 4.80596E-5 41615 0 6.25E-4
1-161166584-G-T p.Arg240Arg synonymous ADAMTS4 4 83222 4.80642E-5 41611 0 8.26638E-6
1-161166585-C-T p.Arg240His missense ADAMTS4 9 83214 1.08155E-4 41607 0 6.37186E-5
1-161166586-G-A p.Arg240Cys missense ADAMTS4 2 83214 2.40344E-5 41607 0 6.37064E-5
1-161166596-C-T p.Ala236Ala synonymous ADAMTS4 30 83196 3.60594E-4 41598 0 8.95E-4
1-161166601-C-G p.Gly235Arg missense ADAMTS4 1 83196 1.20198E-5 41598 0 NA
1-161166602-G-A p.His234His synonymous ADAMTS4 1 83184 1.20215E-5 41592 0 3.18634E-5
1-161166604-G-A p.His234Tyr missense ADAMTS4 1 83178 1.20224E-5 41589 0 4.02172E-6
1-161166610-C-T p.Ala232Thr missense ADAMTS4 47 83128 5.65393E-4 41564 0 4.71972E-4
1-161166611-G-A p.Ala231Ala synonymous ADAMTS4 2 83128 2.40593E-5 41564 0 1.66201E-5
1-161166612-G-A p.Ala231Val missense ADAMTS4 1 83122 1.20305E-5 41561 0 4.0347E-6
1-161166617-C-G p.Lys229Asn missense ADAMTS4 1 83122 1.20305E-5 41561 0 8.32667E-6
1-161166633-A-G p.Val224Ala missense ADAMTS4 11 82960 1.32594E-4 41480 0 6.37389E-5
1-161166649-A-G p.Phe219Leu missense ADAMTS4 1 82860 1.20685E-5 41430 0 8.20143E-6
1-161166670-G-A p.Arg212Cys missense+splice_region ADAMTS4 3 82502 3.63628E-5 41251 0 4.31306E-6
1-161167794-T-C p.Arg208Arg synonymous ADAMTS4 1 79570 1.25676E-5 39785 0 NA
1-161167795-C-T p.Arg208Gln missense ADAMTS4 1 79590 1.25644E-5 39795 0 3.19244E-5
1-161167797-G-A p.Pro207Pro synonymous ADAMTS4 1 79664 1.25527E-5 39832 0 NA
1-161167799-G-T p.Pro207Thr missense ADAMTS4 1 79692 1.25483E-5 39846 0 9.38606E-6
1-161167813-C-T p.Ser202Asn missense ADAMTS4 1 79932 1.25106E-5 39966 0 NA
1-161167826-C-T p.Ala198Thr missense ADAMTS4 1 80070 1.24891E-5 40035 0 2.67499E-5
1-161167832-C-T p.Val196Ile missense ADAMTS4 2 80150 2.49532E-5 40075 0 2.65825E-5
1-161167844-G-A p.Pro192Ser missense ADAMTS4 1 80304 1.24527E-5 40152 0 1.74186E-5
1-161167846-C-A p.Gly191Val missense ADAMTS4 1 80344 1.24465E-5 40172 0 8.68553E-6
1-161167853-C-T p.Gly189Ser missense ADAMTS4 1 80392 1.2439E-5 40196 0 3.19163E-5
1-161167854-G-A p.Ser188Ser synonymous ADAMTS4 3 80414 3.73069E-5 40207 0 1.70911E-5
1-161167867-T-C p.Lys184Arg missense ADAMTS4 3 80654 3.71959E-5 40327 0 8.40082E-5
1-161167870-C-T p.Arg183Gln missense ADAMTS4 1 80690 1.23931E-5 40345 0 6.25E-4
1-161167871-G-A p.Arg183Trp missense ADAMTS4 1 80694 1.23925E-5 40347 0 1.20858E-5
1-161167873-C-T p.Arg182His missense ADAMTS4 1 80738 1.23857E-5 40369 0 2.50694E-5
1-161167874-G-C p.Arg182Gly missense ADAMTS4 1 80854 1.2368E-5 40427 0 NA
1-161167891-G-C p.Pro176Arg missense ADAMTS4 2 81374 2.45779E-5 40687 0 NA
1-161167904-A-G p.Ser172Pro missense ADAMTS4 2 81624 2.45026E-5 40812 0 1.65645E-5
1-161167907-TA-T p.Asn171fs frameshift ADAMTS4 1 81666 1.2245E-5 40833 0 NA
1-161167915-C-T p.Gly168Asp missense ADAMTS4 1 81798 1.22252E-5 40899 0 NA
1-161167919-C-T p.Gly167Arg missense ADAMTS4 1 81892 1.22112E-5 40946 0 NA
1-161167925-G-A p.Leu165Leu synonymous ADAMTS4 1 81996 1.21957E-5 40998 0 8.27075E-6
1-161167933-A-C p.Leu162Arg missense ADAMTS4 2 82026 2.43825E-5 41013 0 NA
1-161167939-A-C p.Leu160Arg missense ADAMTS4 1 82070 1.21847E-5 41035 0 NA
1-161167945-G-GC p.Ala158fs frameshift ADAMTS4 1 82162 1.21711E-5 41081 0 4.01723E-6
1-161167946-C-T p.Ala158Thr missense ADAMTS4 2 82080 2.43665E-5 41040 0 1.60698E-5
1-161167951-C-T p.Arg156Gln missense ADAMTS4 1 82230 1.2161E-5 41115 0 2.81102E-5
1-161167959-T-C p.Leu153Leu synonymous ADAMTS4 1 82378 1.21392E-5 41189 0 8.2672E-6
1-161167962-C-T p.Val152Val synonymous ADAMTS4 1 82396 1.21365E-5 41198 0 NA
1-161167964-C-T p.Val152Met missense ADAMTS4 1 82364 1.21412E-5 41182 0 1.20417E-5
1-161167965-G-A p.Gly151Gly synonymous ADAMTS4 2 82330 2.42925E-5 41165 0 4.01442E-6
1-161167966-C-T p.Gly151Asp missense ADAMTS4 1 82332 1.21459E-5 41166 0 4.0141E-6
1-161167977-T-TC p.Ala148fs frameshift ADAMTS4 1 82202 1.21652E-5 41101 0 NA
1-161167977-TCC-T p.Gly147fs frameshift ADAMTS4 1 82202 1.21652E-5 41101 0 3.19795E-5
1-161167980-C-T p.Gly146Gly synonymous ADAMTS4 4 82184 4.86713E-5 41092 0 4.012E-6
1-161167981-C-T p.Gly146Glu missense ADAMTS4 172 82148 0.00209378 41074 2 0.005625
1-161167989-G-A p.His143His synonymous ADAMTS4 1793 82060 0.0218499 41030 21 0.0216516
1-161168004-C-T p.Ser138Ser synonymous ADAMTS4 20285 81366 0.249306 40683 2667 0.300604
1-161168005-G-A p.Ser138Leu missense ADAMTS4 1 81908 1.22088E-5 40954 0 8.29421E-6
1-161168011-G-A p.Pro136Leu missense ADAMTS4 3 81856 3.66497E-5 40928 0 8.01353E-6
1-161168012-G-A p.Pro136Ser missense ADAMTS4 1 81832 1.22202E-5 40916 0 NA
1-161168020-T-C p.Asn133Ser missense ADAMTS4 5 81810 6.11172E-5 40905 0 2.49112E-5
1-161168028-G-T p.Gly130Gly synonymous ADAMTS4 2 81644 2.44966E-5 40822 0 9.56816E-5
1-161168029-C-A p.Gly130Val missense ADAMTS4 1 81632 1.22501E-5 40816 0 6.37836E-5
1-161168033-T-C p.Thr129Ala missense ADAMTS4 5 81640 6.12445E-5 40820 0 5.03525E-4
1-161168042-T-C p.Thr126Ala missense ADAMTS4 1 81390 1.22865E-5 40695 0 NA
1-161168043-GC-G p.Gly125fs frameshift ADAMTS4 1 81380 1.2288E-5 40690 0 NA
1-161168050-T-G p.Glu123Ala missense ADAMTS4 1 81244 1.23086E-5 40622 0 NA
1-161168056-C-T p.Gly121Glu missense ADAMTS4 3 80986 3.70434E-5 40493 0 5.03525E-4
1-161168059-C-T p.Gly120Asp missense ADAMTS4 1 80936 1.23554E-5 40468 0 NA
1-161168059-C-G p.Gly120Ala missense ADAMTS4 1 80936 1.23554E-5 40468 0 NA
1-161168074-G-A p.Ala115Val missense ADAMTS4 7 80284 8.71905E-5 40142 0 6.41596E-5
1-161168075-C-A p.Ala115Ser missense ADAMTS4 1 80326 1.24493E-5 40163 0 4.00715E-6
1-161168102-C-G p.Gly106Arg missense ADAMTS4 1 79680 1.25502E-5 39840 0 8.03632E-6
1-161168105-C-T p.Glu105Lys missense ADAMTS4 5 79494 6.28978E-5 39747 0 2.63207E-4
1-161168106-G-A p.Val104Val synonymous ADAMTS4 1 79434 1.25891E-5 39717 0 8.49863E-6
1-161168108-C-T p.Val104Ile missense ADAMTS4 5 79554 6.28504E-5 39777 0 6.37836E-5
1-161168116-C-G p.Gly101Ala missense ADAMTS4 1 79442 1.25878E-5 39721 0 6.25E-4
1-161168117-C-T p.Gly101Ser missense ADAMTS4 1 79384 1.2597E-5 39692 0 1.20875E-5
1-161168120-A-G p.Ser100Pro missense ADAMTS4 96 79352 0.0012098 39676 0 9.03941E-4
1-161168125-T-C p.Gln98Arg missense ADAMTS4 3 79458 3.77558E-5 39729 0 1.20922E-5
1-161168135-C-T p.Glu95Lys missense ADAMTS4 6 79562 7.54129E-5 39781 0 9.56267E-5
1-161168145-C-A p.Thr91Thr synonymous ADAMTS4 1 79552 1.25704E-5 39776 0 NA
1-161168145-C-T p.Thr91Thr synonymous ADAMTS4 2 79552 2.51408E-5 39776 0 9.03783E-6
1-161168147-T-C p.Thr91Ala missense ADAMTS4 384 79570 0.00482594 39785 0 0.00436946
1-161168167-C-T p.Arg84His missense ADAMTS4 13 80042 1.62415E-4 40021 0 1.43214E-4
1-161168168-G-A p.Arg84Cys missense ADAMTS4 3 80070 3.74672E-5 40035 0 9.56755E-5
1-161168186-G-T p.Pro78Thr missense ADAMTS4 1 80170 1.24735E-5 40085 0 2.45694E-5
1-161168187-G-A p.Ala77Ala synonymous ADAMTS4 1 80098 1.24847E-5 40049 0 2.45954E-5
1-161168188-G-A p.Ala77Val missense ADAMTS4 27 79972 3.37618E-4 39986 0 3.4711E-4
1-161168189-C-T p.Ala77Thr missense ADAMTS4 5925 79598 0.0744365 39799 283 0.107386
1-161168190-G-A p.Gly76Gly synonymous ADAMTS4 3 79898 3.75479E-5 39949 0 6.25E-4
1-161168191-C-T p.Gly76Asp missense ADAMTS4 14 80068 1.74851E-4 40034 0 4.14356E-4
1-161168193-C-T p.Ser75Ser synonymous ADAMTS4 5 80078 6.24391E-5 40039 0 6.25E-4
1-161168199-A-T p.Pro73Pro synonymous ADAMTS4 1 80294 1.24542E-5 40147 0 NA
1-161168201-G-C p.Pro73Ala missense ADAMTS4 2 80378 2.48824E-5 40189 0 3.18735E-5
1-161168210-T-TGCC p.Gly69dup conservative_inframe_insertion ADAMTS4 3 80532 3.72523E-5 40266 0 9.038E-5
1-161168211-G-A p.Gly69Gly synonymous ADAMTS4 2 80552 2.48287E-5 40276 0 3.18634E-5
1-161168212-C-A p.Gly69Val missense ADAMTS4 2 80556 2.48275E-5 40278 0 1.87126E-5
1-161168213-C-T p.Gly69Ser missense ADAMTS4 3 80576 3.72319E-5 40288 0 6.37267E-5
1-161168214-G-A p.Asn68Asn synonymous ADAMTS4 3 80600 3.72208E-5 40300 0 1.94833E-5
1-161168217-G-A p.Leu67Leu synonymous ADAMTS4 1 80718 1.23888E-5 40359 0 NA
1-161168222-T-TCTCTGGAAA p.Glu65_Lys66insPheProGlu conservative_inframe_insertion ADAMTS4 1 80644 1.24002E-5 40322 0 9.5706E-5
1-161168229-A-G p.Phe63Phe synonymous ADAMTS4 1 80620 1.24039E-5 40310 0 NA
1-161168240-C-G p.Glu60Gln missense ADAMTS4 1 80446 1.24307E-5 40223 0 5.40845E-6
1-161168249-G-C p.Arg57Gly missense ADAMTS4 2 80518 2.48392E-5 40259 0 3.18776E-5
1-161168251-G-A p.Pro56Leu missense ADAMTS4 4 80504 4.9687E-5 40252 0 6.81199E-5
1-161168269-C-T p.Arg50Gln missense ADAMTS4 1 80234 1.24635E-5 40117 0 6.31961E-4
1-161168269-C-G p.Arg50Pro missense ADAMTS4 1 80234 1.24635E-5 40117 0 5.68654E-6
1-161168270-G-A p.Arg50Trp missense ADAMTS4 20 80374 2.48837E-4 40187 0 0.00538731
1-161168270-G-T p.Arg50Arg synonymous ADAMTS4 2 80376 2.4883E-5 40188 0 3.4058E-5
1-161168270-G-C p.Arg50Gly missense ADAMTS4 1 80376 1.24415E-5 40188 0 3.96888E-5
1-161168271-G-C p.Ala49Ala synonymous ADAMTS4 2 80360 2.4888E-5 40180 0 NA
1-161168289-G-T p.Ala43Ala synonymous ADAMTS4 8 80186 9.9768E-5 40093 0 1.91253E-4
1-161168315-C-T p.Val35Met missense ADAMTS4 1 80024 1.24963E-5 40012 0 3.2116E-4
1-161168318-G-A p.Leu34Leu synonymous ADAMTS4 1 79988 1.25019E-5 39994 0 5.76097E-6
1-161168321-AGGAGAGCGGCACAATGG-A p.Pro27fs frameshift ADAMTS4 2 79940 2.50188E-5 39970 0 NA
1-161168321-A-G p.Trp33Arg missense ADAMTS4 1 79940 1.25094E-5 39970 0 5.75043E-6
1-161168328-C-T p.Pro30Pro synonymous ADAMTS4 1 79694 1.2548E-5 39847 0 3.18654E-5
1-161168359-G-A p.Ala20Val missense ADAMTS4 1 78494 1.27398E-5 39247 0 NA
1-161168365-C-G p.Trp18Ser missense ADAMTS4 5 78554 6.36505E-5 39277 0 1.29742E-5
1-161168374-C-T p.Arg15His missense ADAMTS4 1 77592 1.28879E-5 38796 0 1.37929E-5
1-161168375-G-A p.Arg15Cys missense ADAMTS4 3 77172 3.88742E-5 38586 0 NA
1-161168377-C-T p.Gly14Glu missense ADAMTS4 1 77684 1.28727E-5 38842 0 6.90846E-6
1-161168380-G-A p.Ala13Val missense ADAMTS4 1 77322 1.29329E-5 38661 0 NA
1-161168385-G-A p.Gly11Gly synonymous ADAMTS4 1 77876 1.28409E-5 38938 0 6.53902E-6
1-161168393-C-T p.Gly9Arg missense ADAMTS4 11 77348 1.42214E-4 38674 0 0.00254323
1-161168397-A-T p.His7Gln missense ADAMTS4 1 76842 1.30137E-5 38421 0 NA
1-161168398-T-C p.His7Arg missense ADAMTS4 10 76692 1.30392E-4 38346 0 2.86734E-4
1-161168400-C-T p.Ser6Ser synonymous ADAMTS4 2 76200 2.62467E-5 38100 0 8.81523E-5
1-161168422-C-T c.-5G>A 5_prime_UTR_premature_start_codon_gain ADAMTS4 1 72378 1.38164E-5 36189 0 NA
1-161168452-G-A c.-35C>T 5_prime_UTR_premature_start_codon_gain ADAMTS4 4 64782 6.17455E-5 32391 0 3.80518E-4
1-161168462-C-T c.-45G>A 5_prime_UTR_premature_start_codon_gain ADAMTS4 2 62302 3.21017E-5 31151 0 9.55353E-5
1-161168474-C-T c.-57G>A 5_prime_UTR_premature_start_codon_gain ADAMTS4 3 59906 5.00785E-5 29953 0 6.25782E-4
1-161168487-G-C c.-70C>G 5_prime_UTR_premature_start_codon_gain ADAMTS4 1 56078 1.78323E-5 28039 0 NA
1-161168534-G-A c.-117C>T 5_prime_UTR_premature_start_codon_gain ADAMTS4 1 41300 2.42131E-5 20650 0 NA
1-161168564-G-A c.-147C>T 5_prime_UTR_premature_start_codon_gain ADAMTS4 4 33206 1.2046E-4 16603 0 NA
1-161168631-A-G c.-214T>C 5_prime_UTR_premature_start_codon_gain ADAMTS4 3 17262 1.73792E-4 8631 0 3.19244E-5
1-161168714-T-C c.-297A>G 5_prime_UTR_premature_start_codon_gain ADAMTS4 3 5404 5.55144E-4 2702 1 3.18532E-5