Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
11-130318882-G-A p.Gly5Asp missense ADAMTS15 1 80774 1.23802E-5 40387 0 NA
11-130318885-TC-AA p.Ile6Lys missense ADAMTS15 1 81192 1.23165E-5 40596 0 NA
11-130318895-G-A p.Leu9Leu synonymous ADAMTS15 1 81902 1.22097E-5 40951 0 NA
11-130318909-G-C p.Arg14Pro missense ADAMTS15 8 82320 9.71817E-5 41160 0 2.54956E-4
11-130318913-C-T p.Thr15Thr synonymous ADAMTS15 1 82454 1.2128E-5 41227 0 NA
11-130318914-G-T p.Ala16Ser missense ADAMTS15 1 82480 1.21242E-5 41240 0 3.84394E-5
11-130318916-T-C p.Ala16Ala synonymous ADAMTS15 340 82580 0.00411722 41290 2 0.00705645
11-130318917-G-A p.Gly17Arg missense ADAMTS15 1 82608 1.21054E-5 41304 0 3.18735E-5
11-130318922-C-G p.Gly18Gly synonymous ADAMTS15 2 82746 2.41704E-5 41373 0 NA
11-130318930-C-T p.Pro21Leu missense ADAMTS15 2 82842 2.41423E-5 41421 0 9.55901E-5
11-130318935-C-A p.Arg23Arg synonymous ADAMTS15 87 82886 0.00104963 41443 0 0.00334736
11-130318951-C-G p.Pro28Arg missense ADAMTS15 1 83098 1.2034E-5 41549 0 9.35183E-6
11-130318953-A-G p.Ile29Val missense ADAMTS15 1 83112 1.2032E-5 41556 0 NA
11-130318967-G-A p.Pro33Pro synonymous ADAMTS15 1 83160 1.2025E-5 41580 0 NA
11-130318970-C-T p.Asp34Asp synonymous ADAMTS15 2 83158 2.40506E-5 41579 0 9.00398E-6
11-130318973-T-C p.Ile35Ile synonymous ADAMTS15 2 83176 2.40454E-5 41588 0 8.99167E-6
11-130318999-GTCCC-G p.Pro45fs frameshift ADAMTS15 1 83086 1.20357E-5 41543 0 NA
11-130319004-G-C p.Glu46Gln missense ADAMTS15 3 82862 3.62048E-5 41431 0 0.00151057
11-130319008-A-G p.Asp47Gly missense ADAMTS15 6 82984 7.23031E-5 41492 0 5.2997E-5
11-130319011-C-T p.Ser48Phe missense ADAMTS15 1 83078 1.20369E-5 41539 0 NA
11-130319018-T-C p.Asp50Asp synonymous ADAMTS15 1 83116 1.20314E-5 41558 0 NA
11-130319033-T-C p.Phe55Phe synonymous ADAMTS15 7 83234 8.41002E-5 41617 0 5.03525E-4
11-130319052-G-A p.Glu62Lys missense ADAMTS15 7 83252 8.40821E-5 41626 0 3.61539E-5
11-130319063-C-G p.Tyr65* stop_gained ADAMTS15 2 83250 2.4024E-5 41625 0 3.99374E-6
11-130319068-A-G p.His67Arg missense ADAMTS15 17 83230 2.04253E-4 41615 0 3.9931E-5
11-130319083-C-A p.Ala72Asp missense ADAMTS15 3 83202 3.60568E-5 41601 0 7.98301E-6
11-130319106-T-G p.Ser80Ala missense ADAMTS15 891 83096 0.0107225 41548 35 0.0216837
11-130319112-G-C p.Glu82Gln missense ADAMTS15 8 83054 9.63229E-5 41527 0 5.03525E-4
11-130319112-G-A p.Glu82Lys missense ADAMTS15 1 83054 1.20404E-5 41527 0 3.99709E-6
11-130319123-C-T p.Gly85Gly synonymous ADAMTS15 1 82866 1.20677E-5 41433 0 3.33356E-5
11-130319124-G-A p.Val86Ile missense ADAMTS15 1 82890 1.20642E-5 41445 0 NA
11-130319134-A-C p.Gln89Pro missense ADAMTS15 1 82898 1.2063E-5 41449 0 NA
11-130319139-C-G p.Leu91Val missense ADAMTS15 1 82852 1.20697E-5 41426 0 NA
11-130319143-C-G p.Thr92Ser missense ADAMTS15 1 82784 1.20796E-5 41392 0 4.00712E-6
11-130319145-G-C p.Gly93Arg missense ADAMTS15 21 82756 2.53758E-4 41378 0 9.56389E-4
11-130319147-G-C p.Gly93Gly synonymous ADAMTS15 9 82726 1.08793E-4 41363 0 2.80741E-5
11-130319147-G-A p.Gly93Gly synonymous ADAMTS15 1 82726 1.20881E-5 41363 0 8.37872E-6
11-130319152-C-T p.Ser95Phe missense ADAMTS15 1 82714 1.20899E-5 41357 0 NA
11-130319153-T-G p.Ser95Ser synonymous ADAMTS15 1 82712 1.20901E-5 41356 0 NA
11-130319157-G-C p.Asp97His missense ADAMTS15 1 82650 1.20992E-5 41325 0 1.67839E-5
11-130319163-C-A p.Arg99Arg synonymous ADAMTS15 1 82512 1.21194E-5 41256 0 NA
11-130319186-C-T p.Asp106Asp synonymous ADAMTS15 1 81962 1.22008E-5 40981 0 NA
11-130319187-G-T p.Val107Leu missense ADAMTS15 2 81974 2.4398E-5 40987 0 NA
11-130319193-G-A p.Ala109Thr missense ADAMTS15 1 81630 1.22504E-5 40815 0 8.47501E-6
11-130319196-G-A p.Glu110Lys missense ADAMTS15 1 81626 1.2251E-5 40813 0 1.21559E-5
11-130319200-C-T p.Pro111Leu missense ADAMTS15 2 81514 2.45357E-5 40757 0 NA
11-130319201-G-A p.Pro111Pro synonymous ADAMTS15 4 81546 4.90521E-5 40773 0 9.56511E-5
11-130319201-G-T p.Pro111Pro synonymous ADAMTS15 1 81546 1.2263E-5 40773 0 4.05897E-6
11-130319203-A-C p.Asp112Ala missense ADAMTS15 1 81484 1.22723E-5 40742 0 NA
11-130319204-C-A p.Asp112Glu missense ADAMTS15 1 81494 1.22708E-5 40747 0 8.50962E-6
11-130319207-G-A p.Ser113Ser synonymous ADAMTS15 1 81304 1.22995E-5 40652 0 4.06693E-6
11-130319210-C-T p.Phe114Phe synonymous ADAMTS15 1 81236 1.23098E-5 40618 0 1.21956E-5
11-130319216-T-G p.Ala116Ala synonymous ADAMTS15 3 81128 3.69786E-5 40564 0 1.71309E-5
11-130319234-G-A p.Gly122Gly synonymous ADAMTS15 2 80068 2.49788E-5 40034 0 NA
11-130319246-C-A p.Ala126Ala synonymous ADAMTS15 1 79606 1.25619E-5 39803 0 8.28253E-6
11-130319261-C-G p.Gly131Gly synonymous ADAMTS15 1 77758 1.28604E-5 38879 0 NA
11-130319261-C-T p.Gly131Gly synonymous ADAMTS15 24 77756 3.08658E-4 38878 0 1.84026E-4
11-130319265-G-C p.Glu133Gln missense ADAMTS15 56 77558 7.2204E-4 38779 3 0.00304114
11-130319265-G-A p.Glu133Lys missense ADAMTS15 2 77560 2.57865E-5 38780 0 1.05955E-4
11-130319281-C-T p.Pro138Leu missense ADAMTS15 4 75290 5.31279E-5 37645 0 3.18735E-5
11-130319281-C-G p.Pro138Arg missense ADAMTS15 1 75290 1.3282E-5 37645 0 2.23115E-4
11-130319290-A-G p.Asn141Ser missense ADAMTS15 33 74014 4.45862E-4 37007 0 9.24686E-4
11-130319291-T-G p.Asn141Lys missense ADAMTS15 1 73932 1.35259E-5 36966 0 NA
11-130319302-C-A p.Pro145Gln missense ADAMTS15 1 71378 1.40099E-5 35689 0 NA
11-130319306-G-GGCGCA p.Asn150fs frameshift ADAMTS15 1 70618 1.41607E-5 35309 0 4.34998E-6
11-130319307-GC-AA p.Ala147Lys missense ADAMTS15 2 70434 2.83954E-5 35217 0 NA
11-130319314-G-C p.Arg149Pro missense ADAMTS15 2 69326 2.88492E-5 34663 0 NA
11-130319315-C-T p.Arg149Arg synonymous ADAMTS15 6 69386 8.64728E-5 34693 0 3.50382E-5
11-130319317-A-G p.Asn150Ser missense ADAMTS15 1 69360 1.44175E-5 34680 0 4.38516E-6
11-130319322-C-A p.Gln152Lys missense ADAMTS15 1 68788 1.45374E-5 34394 0 4.40987E-6
11-130319332-A-G p.His155Arg missense ADAMTS15 1 67674 1.47767E-5 33837 0 4.47063E-6
11-130319340-C-T p.Gln158* stop_gained ADAMTS15 1 67130 1.48965E-5 33565 0 NA
11-130319342-G-A p.Gln158Gln synonymous ADAMTS15 1 66602 1.50146E-5 33301 0 1.07968E-5
11-130319346-C-T p.Arg160Trp missense ADAMTS15 2 66240 3.01932E-5 33120 0 NA
11-130319347-G-C p.Arg160Pro missense ADAMTS15 1 66476 1.5043E-5 33238 0 NA
11-130319348-G-C p.Arg160Arg synonymous ADAMTS15 1 66496 1.50385E-5 33248 0 3.36814E-5
11-130319354-T-G p.Val162Val synonymous ADAMTS15 1 66308 1.50811E-5 33154 0 NA
11-130319358-G-A p.Gly164Ser missense ADAMTS15 1 66154 1.51162E-5 33077 0 NA
11-130319359-G-C p.Gly164Ala missense ADAMTS15 1 66004 1.51506E-5 33002 0 4.71642E-5
11-130319360-C-A p.Gly164Gly synonymous ADAMTS15 1 65804 1.51966E-5 32902 0 NA
11-130319362-G-A p.Gly165Glu missense ADAMTS15 2 66104 3.02554E-5 33052 0 NA
11-130319363-G-A p.Gly165Gly synonymous ADAMTS15 1 66004 1.51506E-5 33002 0 6.09088E-5
11-130319370-G-A p.Gly168Arg missense ADAMTS15 1 66042 1.51419E-5 33021 0 NA
11-130319372-A-G p.Gly168Gly synonymous ADAMTS15 2 66104 3.02554E-5 33052 0 3.18817E-5
11-130319378-C-T p.Pro170Pro synonymous ADAMTS15 1 66414 1.50571E-5 33207 0 NA
11-130319385-C-T p.Arg173Cys missense ADAMTS15 4 66324 6.031E-5 33162 0 2.66773E-5
11-130319385-C-G p.Arg173Gly missense ADAMTS15 1 66324 1.50775E-5 33162 0 NA
11-130319398-C-G p.Ala177Gly missense ADAMTS15 1 66538 1.5029E-5 33269 0 NA
11-130319399-C-T p.Ala177Ala synonymous ADAMTS15 1 66652 1.50033E-5 33326 0 6.37471E-5
11-130319404-G-T p.Gly179Val missense ADAMTS15 1 66958 1.49347E-5 33479 0 NA
11-130319452-G-C p.Arg195Pro missense ADAMTS15 1 69916 1.43029E-5 34958 0 NA
11-130319465-G-T p.Gly199Gly synonymous ADAMTS15 1 70746 1.41351E-5 35373 0 1.41539E-5
11-130319467-A-G p.Glu200Gly missense ADAMTS15 1 69602 1.43674E-5 34801 0 NA
11-130319477-C-G p.Ser203Arg missense ADAMTS15 1 71438 1.39982E-5 35719 0 NA
11-130319479-G-A p.Arg204Gln missense ADAMTS15 2 71758 2.78715E-5 35879 0 1.39187E-5
11-130319488-C-T p.Ser207Phe missense ADAMTS15 2 73686 2.71422E-5 36843 0 NA
11-130319502-C-A p.Arg212Ser missense ADAMTS15 2 76192 2.62495E-5 38096 0 NA
11-130319507-C-T p.Phe213Phe synonymous ADAMTS15 1 77414 1.29176E-5 38707 0 NA
11-130319515-T-A p.Ile216Asn missense ADAMTS15 7 78588 8.90721E-5 39294 0 0.00202429
11-130319517-C-A p.Pro217Thr missense ADAMTS15 1 78796 1.2691E-5 39398 0 NA
11-130319536-T-A p.Leu223Gln missense ADAMTS15 1 80450 1.24301E-5 40225 0 2.78753E-5
11-130319540-G-A p.Val224Val synonymous ADAMTS15 2 80680 2.47893E-5 40340 0 NA
11-130319555-A-C p.Ser229Ser synonymous ADAMTS15 2 81764 2.44606E-5 40882 0 1.40123E-5
11-130319569-A-G p.His234Arg missense ADAMTS15 1 82142 1.2174E-5 41071 0 3.18898E-5
11-130319571-G-A p.Gly235Ser missense ADAMTS15 254 82162 0.00309145 41081 8 0.00726716
11-130319572-G-A p.Gly235Asp missense ADAMTS15 1 82180 1.21684E-5 41090 0 8.86266E-6
11-130319579-C-T p.Asp237Asp synonymous ADAMTS15 1 82360 1.21418E-5 41180 0 6.37796E-5
11-130319601-C-T p.Leu245Leu synonymous ADAMTS15 2 82678 2.41902E-5 41339 0 1.15714E-5
11-130319615-G-T p.Ala249Ala synonymous ADAMTS15 95 82674 0.00114909 41337 0 0.00554995
11-130319626-A-T p.Tyr253Phe missense ADAMTS15 1 82736 1.20866E-5 41368 0 2.41754E-5
11-130319629-G-T p.Arg254Leu missense ADAMTS15 1 82730 1.20875E-5 41365 0 9.59822E-6
11-130319634-C-T p.Pro256Ser missense ADAMTS15 1 82808 1.20761E-5 41404 0 NA
11-130319634-C-A p.Pro256Thr missense ADAMTS15 2 82808 2.41523E-5 41404 0 NA
11-130319637-A-G p.Ser257Gly missense ADAMTS15 9 82816 1.08675E-4 41408 0 1.27445E-4
11-130319653-T-A p.Ile262Asn missense ADAMTS15 1 82864 1.2068E-5 41432 0 NA
11-130319662-T-C p.Val265Ala missense ADAMTS15 1 82884 1.20651E-5 41442 0 NA
11-130319672-G-A p.Lys268Lys synonymous ADAMTS15 1 82910 1.20613E-5 41455 0 NA
11-130319688-G-A p.Asp274Asn missense ADAMTS15 1 82936 1.20575E-5 41468 0 NA
11-130319689-A-C p.Asp274Ala missense ADAMTS15 1 82934 1.20578E-5 41467 0 NA
11-130319690-T-A p.Asp274Glu missense ADAMTS15 4 82928 4.82346E-5 41464 0 4.00651E-6
11-130319691-C-T p.Arg275Cys missense ADAMTS15 1 82938 1.20572E-5 41469 0 NA
11-130319698-C-A p.Ser277Tyr missense ADAMTS15 1 82924 1.20592E-5 41462 0 NA
11-130319726-C-T p.Ala286Ala synonymous ADAMTS15 1 83024 1.20447E-5 41512 0 2.02344E-5
11-130319732-G-T p.Thr288Thr synonymous ADAMTS15 11 82980 1.32562E-4 41490 0 5.4324E-4
11-130319744-C-A p.Phe292Leu missense ADAMTS15 1 83048 1.20412E-5 41524 0 NA
11-130319751-T-C p.Trp295Arg missense ADAMTS15 2 83040 2.40848E-5 41520 0 6.69378E-5
11-130319754-C-T p.Gln296* stop_gained ADAMTS15 1 83020 1.20453E-5 41510 0 8.37128E-6
11-130319770-A-AAGTG p.Asp304fs frameshift ADAMTS15 1 83016 1.20459E-5 41508 0 4.12814E-6
11-130319789-C-G p.Pro307Pro synonymous ADAMTS15 4 82968 4.82114E-5 41484 0 6.36983E-5
11-130319790-G-A p.Glu308Lys missense ADAMTS15 12 82980 1.44613E-4 41490 0 1.43407E-4
11-130319790-G-C p.Glu308Gln missense ADAMTS15 1 82980 1.20511E-5 41490 0 NA
11-130319808-A-T p.Ile314Phe missense ADAMTS15 1 82868 1.20674E-5 41434 0 NA
11-130319810-C-G p.Ile314Met missense ADAMTS15 1 82842 1.20712E-5 41421 0 8.48666E-6
11-130319811-C-T p.Leu315Phe missense ADAMTS15 1 82854 1.20694E-5 41427 0 3.1841E-5
11-130319819-C-T p.Thr317Thr synonymous ADAMTS15 3 82742 3.62573E-5 41371 0 3.18471E-5
11-130319820-A-T p.Arg318Trp missense ADAMTS15 1 82742 1.20858E-5 41371 0 NA
11-130319822-G-A p.Arg318Arg synonymous ADAMTS15 1 82676 1.20954E-5 41338 0 5.03525E-4
11-130319822-G-C p.Arg318Ser missense ADAMTS15 1 82674 1.20957E-5 41337 0 NA
11-130319833-G-C c.957+8G>C splice_region ADAMTS15 2 82498 2.4243E-5 41249 0 NA
11-130331377-C-T c.958-7C>T splice_region ADAMTS15 6 83196 7.21189E-5 41598 0 1.81398E-4
11-130331378-C-T c.958-6C>T splice_region ADAMTS15 5 83198 6.00976E-5 41599 0 1.97876E-4
11-130331379-G-A c.958-5G>A splice_region ADAMTS15 3 83192 3.60612E-5 41596 0 9.5584E-5
11-130331384-G-A p.Asp320Asn missense+splice_region ADAMTS15 3 83200 3.60577E-5 41600 0 3.18552E-5
11-130331437-C-A p.Thr337Thr synonymous ADAMTS15 3 83210 3.60534E-5 41605 0 NA
11-130331447-C-T p.Pro341Ser missense ADAMTS15 1 83190 1.20207E-5 41595 0 6.59217E-5
11-130331448-C-T p.Pro341Leu missense ADAMTS15 1 83196 1.20198E-5 41598 0 3.18715E-5
11-130331475-A-G p.Asp350Gly missense ADAMTS15 1 83062 1.20392E-5 41531 0 NA
11-130331476-C-T p.Asp350Asp synonymous ADAMTS15 2 83050 2.40819E-5 41525 0 5.03525E-4
11-130331488-A-G p.Pro354Pro synonymous ADAMTS15 2 82894 2.41272E-5 41447 0 1.649E-5
11-130331504-G-A p.Ala360Thr missense ADAMTS15 2 82584 2.42178E-5 41292 0 1.1937E-5
11-130331509-C-T p.His361His synonymous ADAMTS15 10 82428 1.21318E-4 41214 0 7.43408E-5
11-130331510-G-A p.Glu362Lys missense ADAMTS15 2 82352 2.4286E-5 41176 0 3.18451E-5
11-130331515-G-C p.Leu363Leu splice_region+synonymous ADAMTS15 1 82120 1.21773E-5 41060 0 6.37024E-5
11-130331516-G-A p.Gly364Ser missense+splice_region ADAMTS15 1 82086 1.21823E-5 41043 0 8.2776E-6
11-130331521-G-C c.1090+5G>C splice_region ADAMTS15 3 81732 3.67053E-5 40866 0 7.96584E-5
11-130331522-G-A c.1090+6G>A splice_region ADAMTS15 1 81654 1.22468E-5 40827 0 1.6605E-5
11-130331986-C-T p.His365His synonymous ADAMTS15 1 82968 1.20528E-5 41484 0 NA
11-130331987-G-A p.Val366Met missense ADAMTS15 2 82996 2.40975E-5 41498 0 3.19244E-5
11-130331992-C-T p.Phe367Phe synonymous ADAMTS15 3 83062 3.61176E-5 41531 0 NA
11-130331996-A-G p.Met369Val missense ADAMTS15 1 83118 1.20311E-5 41559 0 3.19081E-5
11-130332009-A-T p.Asn373Ile missense ADAMTS15 1 83150 1.20265E-5 41575 0 1.19388E-5
11-130332011-G-A p.Val374Met missense ADAMTS15 4 83156 4.81024E-5 41578 0 1.19374E-5
11-130332014-A-G p.Lys375Glu missense ADAMTS15 1 83152 1.20262E-5 41576 0 NA
11-130332045-G-A p.Arg385Gln missense ADAMTS15 1 82972 1.20523E-5 41486 0 NA
11-130332056-A-G p.Met389Val missense ADAMTS15 1 82870 1.20671E-5 41435 0 1.98907E-5
11-130332066-C-T p.Pro392Leu missense ADAMTS15 1 82750 1.20846E-5 41375 0 6.37105E-5
11-130332067-G-A p.Pro392Pro synonymous ADAMTS15 5 82738 6.04317E-5 41369 0 0.00100705
11-130332076-C-G p.Ile395Met missense ADAMTS15 1 82668 1.20966E-5 41334 0 3.97953E-6
11-130332082-C-T p.Ile397Ile synonymous ADAMTS15 2 82472 2.42507E-5 41236 0 8.24715E-6
11-130332087-G-A p.Arg399His missense ADAMTS15 1 82324 1.21471E-5 41162 0 1.19451E-5
11-130332091-C-T p.Ala400Ala synonymous ADAMTS15 3 82264 3.6468E-5 41132 0 6.36902E-5
11-130332104-G-A p.Ala405Thr missense ADAMTS15 1 82012 1.21933E-5 41006 0 5.03525E-4
11-130332118-C-T p.Ala409Ala synonymous ADAMTS15 1 81698 1.22402E-5 40849 0 8.30096E-6
11-130332127-C-T p.Thr412Thr synonymous ADAMTS15 2 81382 2.45755E-5 40691 0 5.01128E-5
11-130332128-G-A p.Asp413Asn missense ADAMTS15 1 81300 1.23001E-5 40650 0 1.19944E-5
11-130332140-A-T p.Ser417Cys missense ADAMTS15 2 80958 2.47042E-5 40479 0 8.60082E-6
11-130332142-C-T p.Ser417Ser synonymous ADAMTS15 6 80746 7.43071E-5 40373 0 6.43087E-5
11-130332143-G-A p.Gly418Arg missense ADAMTS15 21 80694 2.60242E-4 40347 0 5.73358E-4
11-130332148-C-T p.His419His splice_region+synonymous ADAMTS15 2 80348 2.48917E-5 40174 0 2.64382E-5
11-130332149-G-A p.Gly420Ser missense+splice_region ADAMTS15 5 80238 6.23146E-5 40119 0 8.01211E-5
11-130332395-A-C p.Asp421Ala missense ADAMTS15 1 80946 1.23539E-5 40473 0 9.26097E-6
11-130332416-G-A p.Ser428Asn missense ADAMTS15 1 81060 1.23365E-5 40530 0 NA
11-130332417-C-A p.Ser428Arg missense ADAMTS15 1 81052 1.23378E-5 40526 0 8.99038E-6
11-130332435-C-T p.Pro434Pro synonymous ADAMTS15 2 81240 2.46184E-5 40620 0 6.25E-4
11-130332436-G-A p.Glu435Lys missense ADAMTS15 1 81258 1.23065E-5 40629 0 2.6111E-5
11-130332447-G-C p.Pro438Pro synonymous ADAMTS15 1 81406 1.22841E-5 40703 0 NA
11-130332450-C-T p.Gly439Gly synonymous ADAMTS15 16 81398 1.96565E-4 40699 0 5.03525E-4
11-130332451-G-A p.Ala440Thr missense ADAMTS15 1 81428 1.22808E-5 40714 0 8.57456E-6
11-130332455-G-C p.Ser441Thr missense ADAMTS15 2 81562 2.45212E-5 40781 0 NA
11-130332457-T-C p.Tyr442His missense ADAMTS15 1265 81566 0.0155089 40783 55 0.0256638
11-130332468-C-A p.Ser445Arg missense ADAMTS15 1 81802 1.22246E-5 40901 0 NA
11-130332477-C-T p.Cys448Cys synonymous ADAMTS15 2 82004 2.43891E-5 41002 0 2.53169E-5
11-130332478-G-A p.Glu449Lys missense ADAMTS15 1 82098 1.21806E-5 41049 0 1.68594E-5
11-130332484-G-A p.Ala451Thr missense ADAMTS15 3 82288 3.64573E-5 41144 1 3.18634E-5
11-130332490-G-A p.Gly453Ser missense ADAMTS15 1 82444 1.21294E-5 41222 0 NA
11-130332492-C-T p.Gly453Gly synonymous ADAMTS15 1 82444 1.21294E-5 41222 0 1.67904E-5
11-130332493-G-C p.Val454Leu missense ADAMTS15 6 82496 7.27308E-5 41248 0 8.38518E-6
11-130332493-G-A p.Val454Met missense ADAMTS15 5 82496 6.0609E-5 41248 0 6.25E-4
11-130332518-T-C p.Met462Thr missense ADAMTS15 1 82894 1.20636E-5 41447 0 3.9833E-6
11-130332529-A-G p.Thr466Ala missense ADAMTS15 1 82858 1.20688E-5 41429 0 3.98295E-6
11-130332537-G-A p.Leu468Leu synonymous ADAMTS15 1 82814 1.20753E-5 41407 0 3.18695E-5
11-130332545-C-A p.Thr471Asn missense ADAMTS15 1 82776 1.20808E-5 41388 0 1.66074E-5
11-130332546-C-T p.Thr471Thr synonymous ADAMTS15 2 82762 2.41657E-5 41381 0 1.11647E-4
11-130332547-G-A p.Gly472Arg missense ADAMTS15 5 82790 6.03938E-5 41395 0 0.00125
11-130332558-G-A p.Lys475Lys synonymous ADAMTS15 1 82670 1.20963E-5 41335 0 7.97423E-6
11-130332560-G-A p.Gly476Glu missense ADAMTS15 1 82596 1.21071E-5 41298 0 NA
11-130332566-T-C p.Met478Thr missense ADAMTS15 2 82462 2.42536E-5 41231 0 NA
11-130332578-C-T p.Thr482Ile missense ADAMTS15 5 82792 6.03923E-5 41396 0 7.57292E-5
11-130332580-C-T p.Arg483Cys missense ADAMTS15 31 83006 3.73467E-4 41503 0 1.82297E-4
11-130332581-G-A p.Arg483His missense ADAMTS15 20 83020 2.40906E-4 41510 0 3.10589E-4
11-130332597-C-T p.Ala488Ala synonymous ADAMTS15 7 83034 8.43028E-5 41517 0 8.28624E-5
11-130332607-A-G p.Ser492Gly missense ADAMTS15 4 83030 4.81754E-5 41515 0 2.39095E-5
11-130332615-C-T p.Gly494Gly synonymous ADAMTS15 28 82944 3.37577E-4 41472 0 2.23371E-4
11-130332621-C-T p.Gly496Gly synonymous ADAMTS15 1 82950 1.20555E-5 41475 0 8.34794E-6
11-130332624-G-T p.Lys497Asn missense ADAMTS15 2 82914 2.41214E-5 41457 0 3.19351E-5
11-130332632-T-G p.Leu500Arg missense ADAMTS15 1 82860 1.20685E-5 41430 0 3.18654E-5
11-130332636-A-G p.Lys501Lys synonymous ADAMTS15 13 82842 1.56925E-4 41421 0 1.01194E-4
11-130332640-G-A p.Ala503Thr missense ADAMTS15 4 82780 4.83208E-5 41390 0 4.40677E-5
11-130332645-C-T p.Cys504Cys synonymous ADAMTS15 1 82694 1.20928E-5 41347 0 8.51644E-6
11-130332646-G-A p.Val505Met missense ADAMTS15 2 82696 2.4185E-5 41348 0 4.0202E-6
11-130332665-A-G p.Asn511Ser missense ADAMTS15 454 82334 0.00551413 41167 5 0.0148455
11-130332672-C-A p.His513Gln missense ADAMTS15 1 82224 1.21619E-5 41112 0 NA
11-130332675-GGTGA-G c.1542+1_1542+4delGTGA splice_donor ADAMTS15 1 82126 1.21764E-5 41063 0 8.70777E-6
11-130332676-G-T c.1542+1G>T splice_donor ADAMTS15 2 82114 2.43564E-5 41057 0 4.15721E-6
11-130339157-G-T p.Val515Leu missense+splice_region ADAMTS15 1 78548 1.27311E-5 39274 0 NA
11-130339158-T-A p.Val515Glu missense+splice_region ADAMTS15 1 78512 1.27369E-5 39256 0 7.89366E-6
11-130339161-A-G p.Asp516Gly missense ADAMTS15 1 78502 1.27385E-5 39251 0 1.27445E-4
11-130339163-G-A p.Gly517Ser missense ADAMTS15 1 78534 1.27333E-5 39267 0 NA
11-130339173-C-G p.Ala520Gly missense ADAMTS15 3 78668 3.81349E-5 39334 0 2.73693E-5
11-130339175-A-G p.Lys521Glu missense ADAMTS15 5 78708 6.35259E-5 39354 0 3.18573E-5
11-130339176-A-C p.Lys521Thr missense ADAMTS15 1 78766 1.26958E-5 39383 0 NA
11-130339181-G-T p.Asp523Tyr missense ADAMTS15 1 78700 1.27065E-5 39350 0 9.12575E-6
11-130339185-C-G p.Pro524Arg missense ADAMTS15 2 78694 2.54149E-5 39347 0 NA
11-130339194-C-T p.Pro527Leu missense ADAMTS15 2 78680 2.54194E-5 39340 0 NA
11-130339200-C-T p.Ser529Leu missense ADAMTS15 6 78610 7.63262E-5 39305 0 3.18613E-5
11-130339201-G-A p.Ser529Ser synonymous ADAMTS15 7 78488 8.91856E-5 39244 0 0.00151362
11-130339203-G-A p.Arg530His missense ADAMTS15 1 78434 1.27496E-5 39217 0 7.90002E-6
11-130339204-C-T p.Arg530Arg synonymous ADAMTS15 7 78498 8.91742E-5 39249 0 3.18512E-5
11-130339207-A-G p.Thr531Thr synonymous ADAMTS15 1 78508 1.27376E-5 39254 0 1.58E-5
11-130339218-G-A p.Gly535Asp missense ADAMTS15 1 78272 1.2776E-5 39136 0 NA
11-130339220-G-A p.Val536Met missense ADAMTS15 171 78070 0.00219034 39035 0 0.00280044
11-130339226-C-T p.Leu538Leu synonymous ADAMTS15 1 77710 1.28684E-5 38855 0 6.37349E-5
11-130339236-G-A p.Arg541Lys missense ADAMTS15 2 77398 2.58405E-5 38699 0 3.18552E-5
11-130339245-C-T p.Thr544Ile missense ADAMTS15 1 76980 1.29904E-5 38490 0 NA
11-130339251-C-T p.Pro546Leu missense ADAMTS15 1 76830 1.30157E-5 38415 0 1.63367E-5
11-130339264-C-T p.Asn550Asn synonymous ADAMTS15 4 77086 5.18901E-5 38543 0 6.42862E-5
11-130339265-G-A p.Gly551Arg missense ADAMTS15 1 77106 1.29692E-5 38553 0 6.25E-4
11-130339271-A-G p.Lys553Glu missense ADAMTS15 1 77178 1.29571E-5 38589 0 NA
11-130339279-C-T p.Cys555Cys synonymous ADAMTS15 3 76712 3.91073E-5 38356 0 9.5584E-5
11-130339281-A-G p.Glu556Gly missense ADAMTS15 1 76860 1.30107E-5 38430 0 NA
11-130339294-G-A p.Val560Val synonymous ADAMTS15 1 76038 1.31513E-5 38019 0 1.85017E-5
11-130339301-C-T p.Arg563* stop_gained ADAMTS15 2 75708 2.64173E-5 37854 0 NA
11-130339302-G-A p.Arg563Gln missense ADAMTS15 1 75714 1.32076E-5 37857 0 1.3033E-4
11-130339306-C-T p.Ser564Ser synonymous ADAMTS15 1 75584 1.32303E-5 37792 0 2.46804E-5
11-130339309-C-T p.Cys565Cys synonymous ADAMTS15 1 75442 1.32552E-5 37721 0 NA
11-130339312-T-C p.Asn566Asn synonymous ADAMTS15 43980 73704 0.596711 36852 13484 0.642629
11-130339313-C-T p.Leu567Leu synonymous ADAMTS15 1 75344 1.32725E-5 37672 0 NA
11-130339316-G-A p.Glu568Lys missense ADAMTS15 2 75118 2.66248E-5 37559 0 3.18471E-5
11-130339319-C-A p.Pro569Thr missense ADAMTS15 26 74994 3.46694E-4 37497 0 0.00202634
11-130339326-C-T p.Pro571Leu missense ADAMTS15 1 74672 1.33919E-5 37336 0 NA
11-130339335-G-A c.1720+1G>A splice_donor ADAMTS15 1 74124 1.34909E-5 37062 0 NA
11-130339341-T-C c.1720+7T>C splice_region ADAMTS15 2 73630 2.71628E-5 36815 0 NA
11-130340807-C-T c.1721-8C>T splice_region ADAMTS15 2 82754 2.4168E-5 41377 0 NA
11-130340817-T-G p.Ser575Ala missense+splice_region ADAMTS15 56 82886 6.75627E-4 41443 0 0.00250313
11-130340818-C-A p.Ser575Tyr missense ADAMTS15 4 82902 4.82497E-5 41451 0 1.72604E-5
11-130340819-C-T p.Ser575Ser synonymous ADAMTS15 2 82918 2.41202E-5 41459 0 6.37186E-5
11-130340820-G-A p.Gly576Arg missense ADAMTS15 4 82922 4.82381E-5 41461 0 9.55962E-5
11-130340832-C-T p.Arg580Trp missense ADAMTS15 3 83020 3.61359E-5 41510 0 3.39864E-5
11-130340836-A-G p.Glu581Gly missense ADAMTS15 2 83052 2.40813E-5 41526 0 1.69059E-5
11-130340838-G-A p.Glu582Lys missense ADAMTS15 1 83058 1.20398E-5 41529 0 NA
11-130340839-A-G p.Glu582Gly missense ADAMTS15 1 83054 1.20404E-5 41527 0 1.2751E-4
11-130340840-G-A p.Glu582Glu synonymous ADAMTS15 1 83078 1.20369E-5 41539 0 NA
11-130340858-C-T p.Asn588Asn synonymous ADAMTS15 7 83164 8.4171E-5 41582 0 6.25E-4
11-130340859-G-A p.Gly589Ser missense ADAMTS15 3 83164 3.60733E-5 41582 0 1.67163E-5
11-130340869-A-G p.His592Arg missense ADAMTS15 1 83172 1.20233E-5 41586 0 3.98286E-6
11-130340881-G-A p.Arg596Gln missense ADAMTS15 1 83132 1.20291E-5 41566 0 1.66569E-5
11-130340891-C-T p.Leu599Leu synonymous ADAMTS15 4 83140 4.81116E-5 41570 0 1.59275E-5
11-130340892-G-A p.Ala600Thr missense ADAMTS15 2 83134 2.40575E-5 41567 0 6.25E-4
11-130340912-G-A p.Lys606Lys synonymous ADAMTS15 78 83134 9.38244E-4 41567 1 0.00117812
11-130340918-C-T p.Ser608Ser synonymous ADAMTS15 3 83110 3.60967E-5 41555 0 1.32859E-4
11-130340919-G-A p.Gly609Ser missense ADAMTS15 3 83116 3.60941E-5 41558 0 7.56375E-5
11-130340921-C-T p.Gly609Gly synonymous ADAMTS15 2 83076 2.40743E-5 41538 0 2.49161E-5
11-130340931-C-T p.Arg613Trp missense ADAMTS15 5 83072 6.01888E-5 41536 0 0.00100705
11-130340941-G-A p.Cys616Tyr missense ADAMTS15 1 83006 1.20473E-5 41503 0 8.3102E-6
11-130340953-G-T p.Cys620Phe missense ADAMTS15 1 82898 1.2063E-5 41449 0 NA
11-130340955-C-T p.Arg621* stop_gained ADAMTS15 2 82900 2.41255E-5 41450 0 3.18674E-5
11-130340962-A-G p.Asn623Ser missense ADAMTS15 1420 83080 0.017092 41540 84 0.0417633
11-130340973-T-A p.Tyr627Asn missense ADAMTS15 1 83086 1.20357E-5 41543 0 NA
11-130340976-T-G p.Phe628Val missense ADAMTS15 3 83062 3.61176E-5 41531 0 NA
11-130340980-A-G p.Tyr629Cys missense ADAMTS15 1 83038 1.20427E-5 41519 0 8.42261E-6
11-130340984-G-T p.Val630Val synonymous ADAMTS15 3 83004 3.61428E-5 41502 0 3.1837E-5
11-130340991-C-G p.Pro633Ala missense ADAMTS15 2 82990 2.40993E-5 41495 0 NA
11-130340992-C-T p.Pro633Leu missense ADAMTS15 1 82984 1.20505E-5 41492 0 NA
11-130340995-A-T p.Lys634Met missense+splice_region ADAMTS15 1 82992 1.20494E-5 41496 0 1.20509E-5
11-130341096-G-A c.1903-7G>A splice_region ADAMTS15 4 83114 4.81267E-5 41557 0 NA
11-130341108-G-A p.Val636Val synonymous ADAMTS15 1 83098 1.2034E-5 41549 0 NA
11-130341111-C-T p.Asp637Asp synonymous ADAMTS15 2 83084 2.4072E-5 41542 0 3.46099E-5
11-130341112-G-A p.Gly638Ser missense ADAMTS15 2 83082 2.40726E-5 41541 0 2.58835E-5
11-130341117-G-A p.Thr639Thr synonymous ADAMTS15 1 83108 1.20325E-5 41554 0 NA
11-130341123-C-T p.Cys641Cys synonymous ADAMTS15 2 83142 2.40552E-5 41571 0 6.36862E-5
11-130341141-C-T p.Ser647Ser synonymous ADAMTS15 2 83194 2.40402E-5 41597 0 2.43942E-5
11-130341142-G-A p.Val648Ile missense ADAMTS15 1 83198 1.20195E-5 41599 0 3.18431E-5
11-130341148-G-C p.Val650Leu missense ADAMTS15 1 83222 1.20161E-5 41611 0 4.01188E-6
11-130341170-C-G p.Ala657Gly missense ADAMTS15 5 83258 6.00543E-5 41629 0 9.55231E-5
11-130341170-C-T p.Ala657Val missense ADAMTS15 1 83258 1.20109E-5 41629 0 NA
11-130341176-G-C p.Cys659Ser missense ADAMTS15 1 83260 1.20106E-5 41630 0 NA
11-130341184-A-C p.Asn662His missense ADAMTS15 10 83222 1.20161E-4 41611 1 1.83727E-4
11-130341191-G-T p.Gly664Val missense ADAMTS15 16 83226 1.92248E-4 41613 0 0.00125156
11-130341205-T-C p.Phe669Leu missense ADAMTS15 3 83204 3.6056E-5 41602 0 1.65183E-5
11-130341207-C-T p.Phe669Phe synonymous ADAMTS15 71 83188 8.53489E-4 41594 1 0.00162524
11-130341208-G-A p.Asp670Asn missense ADAMTS15 3 83182 3.60655E-5 41591 0 1.59889E-5
11-130341210-C-T p.Asp670Asp synonymous ADAMTS15 1 83184 1.20215E-5 41592 0 3.99636E-6
11-130341217-G-C p.Gly673Arg missense ADAMTS15 1 83144 1.20273E-5 41572 0 8.00109E-6
11-130341220-G-C p.Val674Leu missense ADAMTS15 1 83126 1.20299E-5 41563 0 2.47778E-5
11-130341227-G-A p.Gly676Glu missense ADAMTS15 1 83084 1.2036E-5 41542 0 NA
11-130341232-G-A p.Asp678Asn missense ADAMTS15 3 83062 3.61176E-5 41531 0 3.18715E-5
11-130341237-T-G p.Asn679Lys missense ADAMTS15 1 83048 1.20412E-5 41524 0 NA
11-130341246-C-T p.Cys682Cys synonymous ADAMTS15 1 82884 1.20651E-5 41442 0 NA
11-130341269-C-T p.Thr690Ile missense ADAMTS15 3 82400 3.64078E-5 41200 0 3.23069E-4
11-130341270-C-G p.Thr690Thr synonymous ADAMTS15 1 82392 1.21371E-5 41196 0 3.18837E-5
11-130341281-G-A c.2078+3G>A splice_region ADAMTS15 2 82036 2.43795E-5 41018 0 3.18654E-5
11-130342936-C-T c.2079-6C>T splice_region ADAMTS15 3 82016 3.65782E-5 41008 0 3.1839E-5
11-130342937-G-A c.2079-5G>A splice_region ADAMTS15 12 81884 1.46549E-4 40942 0 1.27397E-4
11-130342946-G-C p.Gly695Arg missense ADAMTS15 1 82184 1.21678E-5 41092 0 NA
11-130342953-A-G p.Asn697Ser missense ADAMTS15 2 82224 2.43238E-5 41112 0 1.20136E-5
11-130342957-C-T p.Phe698Phe synonymous ADAMTS15 1 82198 1.21657E-5 41099 0 2.80473E-5
11-130342958-G-A p.Val699Met missense ADAMTS15 1 82210 1.2164E-5 41105 0 4.00612E-6
11-130342964-G-T p.Ala701Ser missense ADAMTS15 1 82264 1.2156E-5 41132 0 NA
11-130342964-G-A p.Ala701Thr missense ADAMTS15 1 82264 1.2156E-5 41132 0 3.34113E-5
11-130342965-C-A p.Ala701Asp missense ADAMTS15 1 82228 1.21613E-5 41114 0 4.00619E-6
11-130342972-C-G p.Pro703Pro synonymous ADAMTS15 1 82456 1.21277E-5 41228 0 8.33319E-6
11-130342973-G-A p.Ala704Thr missense ADAMTS15 1 82416 1.21336E-5 41208 0 4.16569E-5
11-130342978-C-T p.Gly705Gly synonymous ADAMTS15 9 82560 1.09012E-4 41280 0 6.25E-4
11-130342979-G-A p.Ala706Thr missense ADAMTS15 1 82598 1.21068E-5 41299 0 8.3051E-6
11-130342981-C-T p.Ala706Ala synonymous ADAMTS15 1 82682 1.20945E-5 41341 0 NA
11-130342990-C-T p.Ile709Ile synonymous ADAMTS15 3 82874 3.61995E-5 41437 0 0.00100705
11-130342993-C-T p.Asp710Asp synonymous ADAMTS15 130 82926 0.00156766 41463 1 0.00331168
11-130342994-A-G p.Ile711Val missense ADAMTS15 2 82948 2.41115E-5 41474 0 NA
11-130342997-C-T p.Arg712Cys missense ADAMTS15 1 83010 1.20467E-5 41505 0 2.48258E-5
11-130342997-C-G p.Arg712Gly missense ADAMTS15 1 83010 1.20467E-5 41505 0 1.27389E-4
11-130342998-G-A p.Arg712His missense ADAMTS15 1 83014 1.20462E-5 41507 0 NA
11-130343003-C-T p.Arg714Cys missense ADAMTS15 1 83056 1.20401E-5 41528 0 8.26829E-6
11-130343011-C-T p.Tyr716Tyr synonymous ADAMTS15 2 83112 2.40639E-5 41556 0 8.25887E-6
11-130343023-C-T p.Ile720Ile synonymous ADAMTS15 788 83136 0.00947845 41568 9 0.0236657
11-130343029-T-C p.Asp722Asp synonymous ADAMTS15 32 83166 3.84773E-4 41583 0 2.74452E-4
11-130343039-C-T p.Leu726Leu synonymous ADAMTS15 2 83164 2.40489E-5 41582 0 1.64997E-5
11-130343056-C-T p.Ser731Ser synonymous ADAMTS15 1 83148 1.20267E-5 41574 0 NA
11-130343077-C-T p.Asn738Asn synonymous ADAMTS15 5 83098 6.01699E-5 41549 0 5.03525E-4
11-130343087-G-A p.Val742Met missense ADAMTS15 4 83028 4.81765E-5 41514 0 7.95729E-6
11-130343087-G-C p.Val742Leu missense ADAMTS15 1 83028 1.20441E-5 41514 0 8.25737E-6
11-130343088-T-C p.Val742Ala missense ADAMTS15 1 83006 1.20473E-5 41503 0 8.25818E-6
11-130343094-C-T p.Ser744Leu missense ADAMTS15 11 82934 1.32636E-4 41467 0 6.3678E-5
11-130343095-G-A p.Ser744Ser synonymous ADAMTS15 5 82912 6.03049E-5 41456 0 8.35814E-5
11-130343097-C-T p.Ala745Val missense ADAMTS15 6 82862 7.24096E-5 41431 0 0.00100705
11-130343098-G-A p.Ala745Ala synonymous ADAMTS15 10 82864 1.2068E-4 41432 0 6.25E-4
11-130343106-G-A p.Arg748Gln missense ADAMTS15 1 82644 1.21001E-5 41322 0 1.19487E-5
11-130343113-G-A p.Leu750Leu synonymous ADAMTS15 18 82542 2.18071E-4 41271 0 8.3654E-5
11-130343135-C-T p.Arg758Trp missense ADAMTS15 33 81758 4.0363E-4 40879 0 0.00111493
11-130343140-C-T p.Tyr759Tyr synonymous ADAMTS15 124 81632 0.00151901 40816 1 0.00328151
11-130343143-C-T p.Ser760Ser synonymous ADAMTS15 541 81364 0.00664913 40682 6 0.0231621
11-130343144-G-A p.Gly761Ser missense ADAMTS15 3 81344 3.68804E-5 40672 0 8.32889E-6
11-130343149-G-A p.Thr762Thr synonymous ADAMTS15 623 80976 0.00769364 40488 12 0.0163809
11-130343150-G-A p.Gly763Ser missense ADAMTS15 3 80972 3.70498E-5 40486 0 3.18532E-5
11-130343157-C-T p.Ala765Val missense ADAMTS15 4 80400 4.97512E-5 40200 0 6.37186E-5
11-130343158-G-A p.Ala765Ala synonymous ADAMTS15 8 80378 9.95297E-5 40189 0 3.18593E-4
11-130343172-A-G p.Gln770Arg missense ADAMTS15 7 79642 8.78933E-5 39821 0 6.3743E-5
11-130343174-G-C p.Ala771Pro missense ADAMTS15 1 79322 1.26068E-5 39661 0 NA
11-130343178-C-T p.Ser772Phe missense ADAMTS15 143 79146 0.00180679 39573 1 0.00442844
11-130343180-C-T p.Arg773Trp missense ADAMTS15 1 78854 1.26817E-5 39427 0 6.25782E-4
11-130343180-C-A p.Arg773Arg synonymous ADAMTS15 1 78854 1.26817E-5 39427 0 NA
11-130343181-G-A p.Arg773Gln missense ADAMTS15 1 78724 1.27026E-5 39362 0 2.01301E-5
11-130343197-G-A p.Pro778Pro synonymous ADAMTS15 13 77840 1.67009E-4 38920 0 0.00312891
11-130343212-C-A p.Val783Val synonymous ADAMTS15 1 77694 1.2871E-5 38847 0 NA
11-130343218-C-T p.Ser785Ser synonymous ADAMTS15 3 77450 3.87347E-5 38725 0 5.03525E-4
11-130343219-G-A p.Val786Met missense ADAMTS15 2 77454 2.58218E-5 38727 0 2.19985E-4
11-130343225-A-AAG p.Met789fs frameshift ADAMTS15 1 77554 1.28942E-5 38777 0 NA
11-130343234-C-T p.Pro791Ser missense ADAMTS15 1 77308 1.29353E-5 38654 0 NA
11-130343236-G-T p.Pro791Pro synonymous ADAMTS15 1 76956 1.29944E-5 38478 0 NA
11-130343237-C-T p.Pro792Ser missense ADAMTS15 1 77132 1.29648E-5 38566 0 4.04541E-6
11-130343246-C-T p.Arg795Cys missense ADAMTS15 2 77458 2.58204E-5 38729 0 1.61801E-5
11-130343253-CCTT-C p.Phe798del disruptive_inframe_deletion ADAMTS15 4 77882 5.13597E-5 38941 0 8.51774E-6
11-130343257-C-T p.Phe798Phe synonymous ADAMTS15 2 77888 2.56779E-5 38944 0 1.70451E-5
11-130343259-A-G p.Tyr799Cys missense ADAMTS15 2 77878 2.56812E-5 38939 0 3.18878E-5
11-130343268-A-G p.Lys802Arg missense ADAMTS15 6 77958 7.69645E-5 38979 0 2.55167E-4
11-130343269-A-G p.Lys802Lys synonymous ADAMTS15 16 78020 2.05076E-4 39010 0 6.37674E-4
11-130343276-C-T p.Arg805Trp missense ADAMTS15 2 77674 2.57486E-5 38837 0 6.37552E-5
11-130343276-C-G p.Arg805Gly missense ADAMTS15 1 77674 1.28743E-5 38837 0 3.18776E-5
11-130343277-G-A p.Arg805Gln missense ADAMTS15 1 77560 1.28932E-5 38780 0 8.54935E-6
11-130343277-G-C p.Arg805Pro missense ADAMTS15 1 77560 1.28932E-5 38780 0 NA
11-130343289-C-G p.Ser809Cys missense ADAMTS15 1 77746 1.28624E-5 38873 0 8.55769E-6
11-130343291-T-G p.Ser810Ala missense ADAMTS15 131 77750 0.00168489 38875 1 0.00267772
11-130343303-G-A p.Asp814Asn missense ADAMTS15 1 77492 1.29046E-5 38746 0 8.57309E-6
11-130343305-C-G p.Asp814Glu missense ADAMTS15 3 77434 3.87427E-5 38717 0 NA
11-130343305-C-T p.Asp814Asp synonymous ADAMTS15 1 77436 1.29139E-5 38718 0 NA
11-130343306-C-T p.Pro815Ser missense ADAMTS15 237 77388 0.00306249 38694 1 0.00442844
11-130343311-G-C p.Arg816Arg synonymous ADAMTS15 1 77078 1.29739E-5 38539 0 NA
11-130343332-C-T p.Asn823Asn synonymous ADAMTS15 1 75910 1.31735E-5 37955 0 NA
11-130343344-C-T p.Ser827Ser synonymous ADAMTS15 2 74316 2.69121E-5 37158 0 NA
11-130343357-G-A p.Val832Met missense ADAMTS15 16 72784 2.19829E-4 36392 0 1.90302E-4
11-130343360-G-C p.Glu833Gln missense ADAMTS15 2 72516 2.75801E-5 36258 0 3.46753E-5
11-130343367-C-T p.Pro835Leu missense ADAMTS15 4 70970 5.63618E-5 35485 0 6.25E-4
11-130343368-G-A p.Pro835Pro synonymous ADAMTS15 259 70632 0.00366689 35316 3 0.020141
11-130343371-C-T p.Asp836Asp synonymous ADAMTS15 3 70180 4.27472E-5 35090 0 3.18492E-5
11-130343372-G-A p.Asp837Asn missense ADAMTS15 5 69860 7.15717E-5 34930 0 3.30912E-5
11-130343378-C-A p.Pro839Thr missense ADAMTS15 1 68792 1.45366E-5 34396 0 NA
11-130343379-C-T p.Pro839Leu missense ADAMTS15 3 68702 4.36669E-5 34351 0 7.01336E-5
11-130343385-C-A p.Ala841Glu missense ADAMTS15 2 68002 2.94109E-5 34001 0 3.18451E-5
11-130343387-C-T p.Arg842Cys missense ADAMTS15 1 67714 1.4768E-5 33857 0 5.28364E-5
11-130343410-G-T p.Gly849Gly synonymous ADAMTS15 1 65238 1.53285E-5 32619 0 1.79979E-5
11-130343412-C-T p.Pro850Leu missense ADAMTS15 1 65264 1.53224E-5 32632 0 4.24268E-6
11-130343413-G-T p.Pro850Pro synonymous ADAMTS15 56 65554 8.54258E-4 32777 0 0.00191241
11-130343413-G-A p.Pro850Pro synonymous ADAMTS15 2 65558 3.05073E-5 32779 0 3.81916E-5
11-130343416-C-T p.Cys851Cys synonymous ADAMTS15 1 65520 1.52625E-5 32760 0 3.82803E-5
11-130343419-C-T p.Ser852Ser synonymous ADAMTS15 6 65454 9.16674E-5 32727 0 7.27326E-5
11-130343420-G-A p.Ala853Thr missense ADAMTS15 190 65398 0.00290529 32699 1 0.00784439
11-130343421-C-T p.Ala853Val missense ADAMTS15 5 65334 7.65298E-5 32667 0 7.29262E-5
11-130343422-G-C p.Ala853Ala synonymous ADAMTS15 15 65582 2.28721E-4 32791 0 2.36475E-4
11-130343422-G-A p.Ala853Ala synonymous ADAMTS15 1 65582 1.52481E-5 32791 0 9.81413E-5
11-130343433-G-A p.Ser857Asn missense ADAMTS15 1 66376 1.50657E-5 33188 0 0.00100908
11-130343446-G-C p.Lys861Asn missense ADAMTS15 1 66480 1.50421E-5 33240 0 NA
11-130343447-C-T p.Arg862Trp missense ADAMTS15 2 66276 3.01768E-5 33138 0 3.18796E-5
11-130343448-G-A p.Arg862Gln missense ADAMTS15 2 66302 3.0165E-5 33151 0 3.18796E-5
11-130343448-G-C p.Arg862Pro missense ADAMTS15 1 66302 1.50825E-5 33151 0 NA
11-130343451-C-T p.Ala863Val missense ADAMTS15 71 66056 0.00107485 33028 0 9.55683E-4
11-130343452-G-A p.Ala863Ala synonymous ADAMTS15 1 66552 1.50258E-5 33276 0 3.91798E-5
11-130343453-G-A p.Val864Met missense ADAMTS15 1 66764 1.49781E-5 33382 0 NA
11-130343462-C-T p.Arg867Trp missense ADAMTS15 3 66968 4.47975E-5 33484 0 5.66091E-5
11-130343463-G-A p.Arg867Gln missense ADAMTS15 1 67088 1.49058E-5 33544 0 3.05176E-5
11-130343466-G-A p.Gly868Asp missense ADAMTS15 1 67296 1.48597E-5 33648 0 NA
11-130343470-C-T p.Ser869Ser synonymous ADAMTS15 19 67614 2.81007E-4 33807 0 9.27767E-4
11-130343471-G-A p.Ala870Thr missense ADAMTS15 1 67434 1.48293E-5 33717 0 3.18979E-5
11-130343473-C-T p.Ala870Ala synonymous ADAMTS15 3 68104 4.40503E-5 34052 0 9.43806E-6
11-130343474-G-A p.Gly871Arg missense ADAMTS15 8 68162 1.17367E-4 34081 0 6.59805E-5
11-130343480-C-T p.Arg873Cys missense ADAMTS15 1 68664 1.45637E-5 34332 0 2.15809E-5
11-130343481-G-A p.Arg873His missense ADAMTS15 3 68786 4.36135E-5 34393 0 2.58474E-5
11-130343481-G-T p.Arg873Leu missense ADAMTS15 1 68786 1.45378E-5 34393 0 NA
11-130343485-G-T p.Thr874Thr synonymous ADAMTS15 9 69822 1.28899E-4 34911 0 4.67386E-5
11-130343491-T-C p.Pro876Pro synonymous ADAMTS15 3 71644 4.18737E-5 35822 0 5.05051E-4
11-130343494-C-G p.Ala877Ala synonymous ADAMTS15 2 72110 2.77354E-5 36055 0 NA
11-130343508-A-G p.His882Arg missense ADAMTS15 3 73878 4.06075E-5 36939 0 9.07112E-6
11-130343510-C-A p.Arg883Arg synonymous ADAMTS15 2 73988 2.70314E-5 36994 0 9.06273E-6
11-130343510-C-T p.Arg883Trp missense ADAMTS15 2 73988 2.70314E-5 36994 0 1.81255E-5
11-130343515-C-A p.Pro884Pro synonymous ADAMTS15 1 74788 1.33711E-5 37394 0 0.00125
11-130343515-C-T p.Pro884Pro synonymous ADAMTS15 1 74788 1.33711E-5 37394 0 6.37511E-5
11-130343516-G-A p.Val885Met missense ADAMTS15 15 74948 2.00139E-4 37474 0 1.59418E-4
11-130343516-G-T p.Val885Leu missense ADAMTS15 2 74948 2.66852E-5 37474 0 8.98925E-6
11-130343523-C-T p.Thr887Ile missense ADAMTS15 1 75916 1.31725E-5 37958 0 4.18989E-6
11-130343524-A-T p.Thr887Thr synonymous ADAMTS15 9 75998 1.18424E-4 37999 1 5.03525E-4
11-130343528-G-A p.Ala889Thr missense ADAMTS15 13 76446 1.70055E-4 38223 0 6.25E-4
11-130343533-C-T p.Cys890Cys synonymous ADAMTS15 4 76892 5.2021E-5 38446 0 6.22532E-5
11-130343534-G-A p.Gly891Arg missense ADAMTS15 2 77278 2.58806E-5 38639 0 7.10366E-5
11-130343544-G-A p.Cys894Tyr missense ADAMTS15 2 78102 2.56075E-5 39051 0 NA
11-130343548-C-G p.Pro895Pro synonymous ADAMTS15 5 78452 6.37332E-5 39226 0 3.5307E-5
11-130343548-C-A p.Pro895Pro synonymous ADAMTS15 1 78452 1.27466E-5 39226 0 1.67072E-5
11-130343558-C-G p.Leu899Val missense ADAMTS15 2 78850 2.53646E-5 39425 0 6.37389E-5
11-130343563-C-T p.Ser900Ser synonymous ADAMTS15 1 79078 1.26457E-5 39539 0 1.14284E-4
11-130343564-G-A p.Ala901Thr missense ADAMTS15 3 79118 3.7918E-5 39559 0 5.27074E-5
11-130343566-C-A p.Ala901Ala synonymous ADAMTS15 111 79400 0.00139798 39700 0 0.00121058
11-130343581-C-T p.Ser906Ser synonymous ADAMTS15 3 79932 3.75319E-5 39966 0 1.59226E-4
11-130343595-G-A p.Arg911Gln missense ADAMTS15 2 80024 2.49925E-5 40012 0 2.10962E-5
11-130343596-G-C p.Arg911Arg synonymous ADAMTS15 1 80058 1.24909E-5 40029 0 1.74557E-5
11-130343609-C-T p.Arg916Cys missense ADAMTS15 1 80004 1.24994E-5 40002 0 9.55475E-5
11-130343622-G-A p.Cys920Tyr missense ADAMTS15 1 79998 1.25003E-5 39999 0 NA
11-130343627-G-A p.Gly922Ser missense ADAMTS15 2 79946 2.50169E-5 39973 0 1.27393E-5
11-130343629-C-T p.Gly922Gly synonymous ADAMTS15 1 79908 1.25144E-5 39954 0 NA
11-130343632-C-T p.His923His synonymous ADAMTS15 2 79934 2.50206E-5 39967 0 6.37389E-5
11-130343633-G-A p.Gly924Arg missense ADAMTS15 1 80004 1.24994E-5 40002 0 2.61238E-5
11-130343638-C-A p.Gly925Gly synonymous ADAMTS15 2 79854 2.50457E-5 39927 0 NA
11-130343639-C-T p.Arg926Trp missense ADAMTS15 4 79838 5.01015E-5 39919 0 6.37592E-5
11-130343640-G-A p.Arg926Gln missense ADAMTS15 13 79846 1.62813E-4 39923 0 0.00100806
11-130343646-T-A p.Leu928Gln missense ADAMTS15 2 79822 2.50557E-5 39911 0 4.25822E-6
11-130343654-G-A p.Asp931Asn missense ADAMTS15 1 79814 1.25291E-5 39907 0 NA
11-130343657-C-T p.Gln932* stop_gained ADAMTS15 2 79850 2.5047E-5 39925 0 3.18593E-5
11-130343672-C-T p.Arg937Cys missense ADAMTS15 3 79842 3.75742E-5 39921 0 1.28394E-5
11-130343673-G-T p.Arg937Leu missense ADAMTS15 1 79810 1.25298E-5 39905 0 NA
11-130343698-C-T p.Cys945Cys synonymous ADAMTS15 1 79886 1.25178E-5 39943 0 6.3743E-5
11-130343699-G-A p.Val946Ile missense ADAMTS15 1 79904 1.2515E-5 39952 0 1.72138E-5
11-130343702-C-T p.Leu947Leu synonymous ADAMTS15 647 79942 0.00809337 39971 12 0.015052
11-130343707-G-A p.Arg948Arg synonymous ADAMTS15 1 79860 1.25219E-5 39930 0 NA
11-130343709-C-T p.Pro949Leu missense ADAMTS15 1 79844 1.25244E-5 39922 0 6.74556E-5
11-130343710-G-A p.Pro949Pro synonymous ADAMTS15 4 79820 5.01128E-5 39910 1 2.91562E-5