Variant

Variant ID Consequence Effect Gene AC AN AF NS NHOM maxEAF
14-70924076-C-T c.-141C>T 5_prime_UTR_premature_start_codon_gain ADAM21 1 79480 1.25818E-5 39740 0 NA
14-70924204-C-T c.-13C>T 5_prime_UTR_premature_start_codon_gain ADAM21 11 82110 1.33967E-4 41055 0 3.20061E-4
14-70924215-TA-T p.Met1fs frameshift ADAM21 1 82038 1.21895E-5 41019 0 3.20328E-5
14-70924229-G-A p.Gly5Arg missense ADAM21 1 81774 1.22288E-5 40887 0 4.2356E-6
14-70924237-C-A p.Leu7Leu synonymous ADAM21 18791 67898 0.276753 33949 3415 0.334008
14-70924238-G-A p.Val8Met missense ADAM21 1 81674 1.22438E-5 40837 0 8.56326E-6
14-70924248-GA-G p.Val12fs frameshift ADAM21 3 81862 3.6647E-5 40931 1 NA
14-70924249-A-G p.Arg11Arg synonymous ADAM21 35727 72990 0.489478 36495 10109 0.540297
14-70924250-G-T p.Val12Phe missense ADAM21 2 81886 2.44242E-5 40943 0 2.12922E-5
14-70924253-A-G p.Thr13Ala missense ADAM21 1 81980 1.21981E-5 40990 0 NA
14-70924261-G-C p.Leu15Leu synonymous ADAM21 1 82236 1.21601E-5 41118 0 8.48191E-6
14-70924271-C-T p.Leu19Phe missense ADAM21 3 82486 3.63698E-5 41243 0 3.1902E-5
14-70924286-T-C p.Ser24Pro missense ADAM21 797 82700 0.00963724 41350 28 0.0212121
14-70924294-C-T p.Ser26Ser synonymous ADAM21 70 82578 8.47683E-4 41289 0 0.00528541
14-70924295-G-A p.Gly27Ser missense ADAM21 1 82856 1.20691E-5 41428 0 6.25E-4
14-70924297-C-G p.Gly27Gly synonymous ADAM21 1 82872 1.20668E-5 41436 0 3.18695E-5
14-70924316-T-G p.Ser34Ala missense ADAM21 1 82998 1.20485E-5 41499 0 4.14195E-5
14-70924317-C-T p.Ser34Phe missense ADAM21 1 83024 1.20447E-5 41512 0 NA
14-70924319-C-T p.Gln35* stop_gained ADAM21 1 83036 1.2043E-5 41518 0 3.18492E-5
14-70924335-C-T p.Pro40Leu missense ADAM21 71 82826 8.57219E-4 41413 0 0.0387714
14-70924336-G-A p.Pro40Pro synonymous ADAM21 6 83110 7.21935E-5 41555 0 2.3889E-5
14-70924340-G-T p.Val42Leu missense ADAM21 1 83138 1.20282E-5 41569 0 NA
14-70924353-TGAA-T p.Lys47del conservative_inframe_deletion ADAM21 1 83248 1.20123E-5 41624 0 NA
14-70924358-G-A p.Val48Met missense ADAM21 1 83258 1.20109E-5 41629 0 6.61223E-5
14-70924359-T-A p.Val48Glu missense ADAM21 1 83244 1.20129E-5 41622 0 NA
14-70924360-G-T p.Val48Val synonymous ADAM21 1 83260 1.20106E-5 41630 0 8.26501E-6
14-70924364-A-G p.Ser50Gly missense ADAM21 7 83260 8.4074E-5 41630 0 2.86716E-4
14-70924369-G-A p.Arg51Arg synonymous ADAM21 1 83272 1.20088E-5 41636 0 8.26351E-6
14-70924391-G-T p.Gly59* stop_gained ADAM21 1 83306 1.20039E-5 41653 0 8.25805E-6
14-70924404-A-G p.Tyr63Cys missense ADAM21 1 83316 1.20025E-5 41658 0 3.18776E-5
14-70924412-C-A p.Arg66Arg synonymous ADAM21 8 83302 9.60361E-5 41651 0 5.18304E-5
14-70924413-G-A p.Arg66Gln missense ADAM21 160 83294 0.00192091 41647 0 0.00545072
14-70924422-G-A p.Gly69Asp missense ADAM21 5 83270 6.00456E-5 41635 0 0.00100705
14-70924433-G-A p.Val73Ile missense ADAM21 6 83288 7.20392E-5 41644 0 0.00100705
14-70924433-G-C p.Val73Leu missense ADAM21 2 83288 2.40131E-5 41644 0 2.47492E-5
14-70924439-CAT-C p.Met76fs frameshift ADAM21 1 83262 1.20103E-5 41631 0 NA
14-70924445-A-T p.Arg77Trp missense ADAM21 1 83232 1.20146E-5 41616 0 NA
14-70924450-C-T p.Val78Val synonymous ADAM21 2822 79002 0.0357206 39501 108 0.377151
14-70924457-C-T p.Leu81Phe missense ADAM21 1 83128 1.20296E-5 41564 0 NA
14-70924459-C-A p.Leu81Leu synonymous ADAM21 2 83092 2.40697E-5 41546 0 NA
14-70924462-A-G p.Leu82Leu synonymous ADAM21 66799 80488 0.829925 40244 28179 0.842303
14-70924471-A-G p.Arg85Arg synonymous ADAM21 14 82978 1.68719E-4 41489 0 5.43478E-4
14-70924480-A-C p.Pro88Pro synonymous ADAM21 1 82920 1.20598E-5 41460 0 3.98441E-6
14-70924486-C-T p.Phe90Phe synonymous ADAM21 3 82866 3.6203E-5 41433 0 7.96191E-6
14-70924489-C-T p.Thr91Thr synonymous ADAM21 14 82828 1.69025E-4 41414 0 6.51407E-4
14-70924489-C-G p.Thr91Thr synonymous ADAM21 1 82840 1.20715E-5 41420 0 3.98162E-6
14-70924492-C-T p.Tyr92Tyr synonymous ADAM21 6 82834 7.2434E-5 41417 0 9.58222E-5
14-70924499-G-A p.Asp95Asn missense ADAM21 2 82770 2.41633E-5 41385 0 3.19387E-5
14-70924501-C-G p.Asp95Glu missense ADAM21 56529 63040 0.896716 31520 25419 0.909546
14-70924502-C-T p.Arg96Cys missense ADAM21 1 82696 1.20925E-5 41348 0 9.59632E-5
14-70924503-G-A p.Arg96His missense ADAM21 7 82710 8.46331E-5 41355 0 0.0020141
14-70924507-A-C p.Ala97Ala synonymous ADAM21 21943 72236 0.303768 36118 4169 0.33044
14-70924508-C-T p.Leu98Phe missense ADAM21 5 82728 6.0439E-5 41364 0 3.19489E-5
14-70924519-T-C p.Asp101Asp synonymous ADAM21 3 82762 3.62485E-5 41381 0 1.27885E-4
14-70924526-T-C p.Phe104Leu missense ADAM21 1 82806 1.20764E-5 41403 0 NA
14-70924531-C-T p.Ile105Ile synonymous ADAM21 1 82816 1.2075E-5 41408 0 1.19423E-5
14-70924542-G-C p.Cys109Ser missense ADAM21 136 82614 0.00164621 41307 0 0.00655242
14-70924553-G-A p.Gly113Ser missense ADAM21 15 83020 1.80679E-4 41510 0 5.1579E-4
14-70924558-C-T p.Tyr114Tyr synonymous ADAM21 4517 80072 0.0564117 40036 184 0.10875
14-70924559-G-A p.Val115Met missense ADAM21 7 83054 8.42825E-5 41527 0 1.1585E-4
14-70924566-C-G p.Ala117Gly missense ADAM21 22318 79712 0.279983 39856 3554 0.3429
14-70924566-CA-GT p.Ala117Gly missense ADAM21 25 83064 3.00973E-4 41532 5 NA
14-70924567-A-T p.Ala117Ala synonymous ADAM21 22374 79816 0.28032 39908 3559 0.34139
14-70924587-TG-T p.Phe125fs frameshift ADAM21 2 83114 2.40633E-5 41557 0 3.99116E-6
14-70924597-T-C p.Ala127Ala synonymous ADAM21 2 83120 2.40616E-5 41560 0 NA
14-70924602-T-G p.Phe129Cys missense ADAM21 2796 81692 0.0342261 40846 89 0.245855
14-70924603-TG-T p.Gly131fs frameshift ADAM21 1 83130 1.20294E-5 41565 0 NA
14-70924613-C-A p.Arg133Arg synonymous ADAM21 50 83070 6.01902E-4 41535 0 0.00150169
14-70924614-G-A p.Arg133Gln missense ADAM21 1 83098 1.2034E-5 41549 0 1.19853E-5
14-70924619-G-C p.Val135Leu missense ADAM21 4 83080 4.81464E-5 41540 0 2.35702E-4
14-70924620-T-C p.Val135Ala missense ADAM21 1 83076 1.20372E-5 41538 0 NA
14-70924630-A-C p.Ile138Ile synonymous ADAM21 1 83074 1.20375E-5 41537 0 8.28967E-6
14-70924636-C-T p.Gly140Gly synonymous ADAM21 1 83032 1.20435E-5 41516 0 NA
14-70924643-T-C p.Tyr143His missense ADAM21 10 83012 1.20465E-4 41506 0 0.0317221
14-70924655-C-T p.Pro147Ser missense ADAM21 1 83022 1.2045E-5 41511 0 NA
14-70924664-C-A p.His150Asn missense ADAM21 1 83018 1.20456E-5 41509 0 NA
14-70924687-G-A p.Leu157Leu synonymous ADAM21 1 83022 1.2045E-5 41511 0 8.63379E-6
14-70924692-A-AC p.Lys160fs frameshift ADAM21 1 82970 1.20525E-5 41485 0 0.00196591
14-70924693-T-C p.Tyr159Tyr synonymous ADAM21 10516 77838 0.135101 38919 1270 0.183023
14-70924693-T-A p.Tyr159* stop_gained ADAM21 1 82866 1.20677E-5 41433 0 0.00211232
14-70924695-AGATAAAC-A p.Ile161fs frameshift ADAM21 3 82878 3.61978E-5 41439 0 0.00510089
14-70924696-G-A p.Lys160Lys synonymous ADAM21 9962 76824 0.129673 38412 1246 0.18295
14-70924696-GA-AG p.LysIle160LysVal missense ADAM21 11 82864 1.32748E-4 41432 2 NA
14-70924697-A-G p.Ile161Val missense ADAM21 9876 76686 0.128785 38343 1242 0.182824
14-70924704-G-C p.Ser163Thr missense ADAM21 2 83044 2.40836E-5 41522 1 8.4832E-6
14-70924728-T-C p.Met171Thr missense ADAM21 4 83130 4.81174E-5 41565 0 3.18593E-5
14-70924736-G-A p.Gly174Ser missense ADAM21 16 82726 1.9341E-4 41363 0 0.00805639
14-70924747-G-A p.Glu177Glu synonymous ADAM21 1 83194 1.20201E-5 41597 0 NA
14-70924751-G-T p.Glu179* stop_gained ADAM21 1 83200 1.20192E-5 41600 0 8.253E-6
14-70924754-G-A p.Val180Ile missense ADAM21 54 83200 6.49038E-4 41600 1 0.0060423
14-70924754-G-T p.Val180Leu missense ADAM21 8 83208 9.61446E-5 41604 0 6.60164E-5
14-70924754-G-C p.Val180Leu missense ADAM21 1 83208 1.20181E-5 41604 0 NA
14-70924760-C-T p.Arg182Cys missense ADAM21 2 83208 2.40361E-5 41604 0 9.89985E-5
14-70924761-G-A p.Arg182His missense ADAM21 1 83218 1.20166E-5 41609 0 3.18735E-5
14-70924763-C-A p.Gln183Lys missense ADAM21 3 83224 3.60473E-5 41612 0 1.27486E-4
14-70924769-T-C p.Leu185Leu synonymous ADAM21 3 83226 3.60464E-5 41613 0 5.17121E-5
14-70924772-G-T p.Glu186* stop_gained ADAM21 1 83222 1.20161E-5 41611 0 6.36487E-5
14-70924788-A-G p.Glu191Gly missense ADAM21 1 83220 1.20163E-5 41610 0 3.18634E-5
14-70924791-A-T p.Asn192Ile missense ADAM21 1 83226 1.20155E-5 41613 0 NA
14-70924792-C-T p.Asn192Asn synonymous ADAM21 1 83228 1.20152E-5 41614 0 NA
14-70924812-C-T p.Ser199Phe missense ADAM21 4 82958 4.82172E-5 41479 0 0.0015121
14-70924818-G-C p.Gly201Ala missense ADAM21 1 83210 1.20178E-5 41605 0 NA
14-70924832-C-T p.His206Tyr missense ADAM21 1 83142 1.20276E-5 41571 0 1.64883E-5
14-70924838-T-C p.Trp208Arg missense ADAM21 1 83104 1.20331E-5 41552 0 3.98029E-6
14-70924849-G-A p.Glu211Glu synonymous ADAM21 1 82908 1.20616E-5 41454 0 1.19533E-5
14-70924850-CTAG-C p.Val213del disruptive_inframe_deletion ADAM21 1 82888 1.20645E-5 41444 0 3.98451E-6
14-70924852-A-C p.Leu212Leu synonymous ADAM21 36219 79298 0.456745 39649 8767 0.536327
14-70924852-A-T p.Leu212Leu synonymous ADAM21 2 82876 2.41324E-5 41438 1 NA
14-70924855-T-C p.Val213Val synonymous ADAM21 1 82860 1.20685E-5 41430 0 3.98448E-6
14-70924861-G-A p.Val215Val synonymous ADAM21 3 82826 3.62205E-5 41413 0 8.26843E-6
14-70924862-G-A p.Val216Met missense ADAM21 1 82794 1.20782E-5 41397 0 NA
14-70924870-T-C p.His218His synonymous ADAM21 6 82810 7.2455E-5 41405 0 6.37633E-5
14-70924873-T-C p.Asp219Asp synonymous ADAM21 1 82826 1.20735E-5 41413 0 3.18837E-5
14-70924873-TTTCTTCATTTACTCTCAA-T p.Phe220_Gln225del conservative_inframe_deletion ADAM21 1 82826 1.20735E-5 41413 0 NA
14-70924894-C-T p.Ser226Ser synonymous ADAM21 1 83004 1.20476E-5 41502 0 NA
14-70924903-A-C p.Ser229Ser synonymous ADAM21 1 83052 1.20406E-5 41526 0 NA
14-70924910-C-T p.Gln232* stop_gained ADAM21 1 83058 1.20398E-5 41529 0 8.256E-6
14-70924927-T-G p.Leu237Leu synonymous ADAM21 1 83106 1.20328E-5 41553 0 NA
14-70924943-G-T p.Asp243Tyr missense ADAM21 2 83148 2.40535E-5 41574 0 3.97931E-6
14-70924950-T-C p.Met245Thr missense ADAM21 3 83166 3.60724E-5 41583 0 1.5917E-5
14-70924951-G-A p.Met245Ile missense ADAM21 3 83164 3.60733E-5 41582 0 2.3877E-5
14-70924955-A-C p.Lys247Gln missense ADAM21 10503 77150 0.136137 38575 1221 0.19003
14-70924957-G-A p.Lys247Lys synonymous ADAM21 1 83162 1.20247E-5 41581 0 8.25164E-6
14-70924972-C-T p.Tyr252Tyr synonymous ADAM21 1 83202 1.20189E-5 41601 0 3.98061E-6
14-70924996-T-C p.Ile260Ile synonymous ADAM21 2 83238 2.40275E-5 41619 0 6.76902E-5
14-70925013-T-G p.Val266Gly missense ADAM21 1 83244 1.20129E-5 41622 0 NA
14-70925014-T-C p.Val266Val synonymous ADAM21 1 83252 1.20117E-5 41626 0 NA
14-70925021-A-G p.Met269Val missense ADAM21 3 83252 3.60352E-5 41626 0 7.95855E-6
14-70925028-G-A p.Ser271Asn missense ADAM21 1 83250 1.2012E-5 41625 0 8.24865E-6
14-70925031-T-C p.Ile272Thr missense ADAM21 2 83252 2.40234E-5 41626 0 3.97867E-6
14-70925035-A-G p.Glu273Glu synonymous ADAM21 21 83258 2.52228E-4 41629 1 4.93367E-4
14-70925038-G-A p.Gln274Gln synonymous ADAM21 69 83264 8.28689E-4 41632 0 0.00503525
14-70925043-T-G p.Leu276Arg missense ADAM21 1 83262 1.20103E-5 41631 0 3.9788E-6
14-70925047-C-T p.Asn277Asn synonymous ADAM21 4 83264 4.804E-5 41632 0 4.94821E-5
14-70925048-G-A p.Asp278Asn missense ADAM21 2 83268 2.40188E-5 41634 0 NA
14-70925048-G-T p.Asp278Tyr missense ADAM21 1 83268 1.20094E-5 41634 0 3.97896E-6
14-70925057-C-T p.Gln281* stop_gained ADAM21 4 83254 4.80457E-5 41627 0 1.19359E-5
14-70925059-A-G p.Gln281Gln synonymous ADAM21 1 83258 1.20109E-5 41629 0 NA
14-70925060-T-C p.Trp282Arg missense ADAM21 1 83242 1.20132E-5 41621 0 8.24729E-6
14-70925063-A-G p.Lys283Glu missense ADAM21 2 83246 2.40252E-5 41623 0 7.95691E-5
14-70925073-G-A p.Ser286Asn missense ADAM21 1 83238 1.20137E-5 41619 0 NA
14-70925076-T-G p.Leu287Arg missense ADAM21 5 83236 6.00702E-5 41618 0 6.3674E-5
14-70925089-G-T p.Gln291His missense ADAM21 1 83198 1.20195E-5 41599 0 2.78538E-5
14-70925098-T-C p.Ala294Ala synonymous ADAM21 1 83190 1.20207E-5 41595 0 NA
14-70925102-C-T p.His296Tyr missense ADAM21 120 83206 0.0014422 41603 4 0.00267469
14-70925103-A-C p.His296Pro missense ADAM21 2 83210 2.40356E-5 41605 0 3.98035E-6
14-70925124-T-G p.Leu303Arg missense ADAM21 15 83138 1.80423E-4 41569 0 4.45831E-4
14-70925139-G-T p.Gly308Val missense ADAM21 2 82970 2.41051E-5 41485 0 6.36821E-5
14-70925161-A-G p.Ile315Met missense ADAM21 17 82846 2.052E-4 41423 0 5.29826E-4
14-70925161-A-C p.Ile315Ile synonymous ADAM21 1 82846 1.20706E-5 41423 0 NA
14-70925165-C-T p.Arg317Cys missense ADAM21 4 82758 4.83337E-5 41379 0 5.03525E-4
14-70925166-G-A p.Arg317His missense ADAM21 12 82718 1.45071E-4 41359 0 5.03525E-4
14-70925168-C-T p.Pro318Ser missense ADAM21 2 82682 2.41891E-5 41341 0 1.65333E-5
14-70925172-C-T p.Pro319Leu missense ADAM21 2 82662 2.41949E-5 41331 0 1.65396E-5
14-70925173-T-C p.Pro319Pro synonymous ADAM21 1 82644 1.21001E-5 41322 0 NA
14-70925209-C-G p.Thr331Thr synonymous ADAM21 2 82300 2.43013E-5 41150 0 NA
14-70925214-C-G p.Ser333Cys missense ADAM21 1 82182 1.21681E-5 41091 0 NA
14-70925216-C-T p.Leu334Phe missense ADAM21 3 82108 3.65372E-5 41054 0 NA
14-70925221-T-C p.Phe335Phe synonymous ADAM21 5 81820 6.11098E-5 40910 0 3.19142E-5
14-70925245-A-G p.Leu343Leu synonymous ADAM21 1 80602 1.24066E-5 40301 0 4.0084E-6
14-70925251-T-C p.His345His synonymous ADAM21 1 80234 1.24635E-5 40117 0 3.19857E-5
14-70925253-C-T p.Thr346Met missense ADAM21 1 80138 1.24785E-5 40069 0 3.20803E-5
14-70925254-G-A p.Thr346Thr synonymous ADAM21 1 80028 1.24956E-5 40014 0 4.00943E-6
14-70925257-A-G p.Leu347Leu synonymous ADAM21 67192 67986 0.988321 33993 33242 0.994014
14-70925258-G-C p.Gly348Arg missense ADAM21 1 79920 1.25125E-5 39960 0 NA
14-70925261-A-G p.Met349Val missense ADAM21 1 80024 1.24963E-5 40012 0 8.30592E-6
14-70925263-G-A p.Met349Ile missense ADAM21 1 80004 1.24994E-5 40002 0 NA
14-70925268-A-G p.His351Arg missense ADAM21 7 80192 8.72905E-5 40096 0 6.38978E-5
14-70925288-T-G p.Cys358Gly missense ADAM21 1 80640 1.24008E-5 40320 0 2.49464E-5
14-70925290-TG-T p.Glu360fs frameshift ADAM21 1 80684 1.2394E-5 40342 0 NA
14-70925300-G-A p.Gly362Ser missense ADAM21 2 80964 2.47023E-5 40482 0 NA
14-70925320-T-C p.Phe368Phe synonymous ADAM21 384 82078 0.00467848 41039 9 0.00974005
14-70925326-G-A p.Val370Val synonymous ADAM21 1 82280 1.21536E-5 41140 0 4.00583E-6
14-70925356-C-T p.Tyr380Tyr synonymous ADAM21 3 83066 3.61159E-5 41533 0 5.28541E-4
14-70925357-G-A p.Ala381Thr missense ADAM21 1 83082 1.20363E-5 41541 0 3.19142E-5
14-70925377-C-T p.Thr387Thr synonymous ADAM21 1 83218 1.20166E-5 41609 0 NA
14-70925379-T-A p.Leu388* stop_gained ADAM21 1 83234 1.20143E-5 41617 0 3.18573E-5
14-70925383-C-G p.Asn389Lys missense ADAM21 1 83238 1.20137E-5 41619 0 NA
14-70925401-T-A p.His395Gln missense ADAM21 12 83268 1.44113E-4 41634 0 5.03525E-4
14-70925439-G-A p.Arg408His missense ADAM21 4 83296 4.80215E-5 41648 0 1.99045E-5
14-70925449-T-C p.Asn411Asn synonymous ADAM21 1 83340 1.1999E-5 41670 0 3.98118E-6
14-70925483-G-C p.Gly423Arg missense ADAM21 1 83358 1.19964E-5 41679 0 NA
14-70925492-C-A p.Gln426Lys missense ADAM21 3 83362 3.59876E-5 41681 0 3.29913E-5
14-70925501-G-C p.Glu429Gln missense ADAM21 3320 83180 0.0399134 41590 93 0.0589124
14-70925509-C-T p.Asp431Asp synonymous ADAM21 216 83334 0.00259198 41667 4 0.00398191
14-70925510-G-A p.Ala432Thr missense ADAM21 7 83372 8.3961E-5 41686 0 6.37064E-5
14-70925520-T-C p.Leu435Pro missense ADAM21 2 83364 2.39912E-5 41682 0 6.5962E-5
14-70925521-G-A p.Leu435Leu synonymous ADAM21 2 83362 2.39917E-5 41681 0 4.37515E-5
14-70925536-A-G p.Leu440Leu synonymous ADAM21 1 83354 1.1997E-5 41677 0 NA
14-70925549-G-C p.Ala445Pro missense ADAM21 9 83330 1.08004E-4 41665 0 2.80232E-4
14-70925559-T-A p.Phe448Tyr missense ADAM21 5 83338 5.99966E-5 41669 0 5.03525E-4
14-70925584-G-A p.Lys456Lys synonymous ADAM21 148 83268 0.00177739 41634 1 0.00318552
14-70925593-A-G p.Pro459Pro synonymous ADAM21 12 83284 1.44085E-4 41642 0 6.25E-4
14-70925608-T-C p.Cys464Cys synonymous ADAM21 1 83266 1.20097E-5 41633 0 NA
14-70925633-C-T p.Leu473Phe missense ADAM21 19 83214 2.28327E-4 41607 0 7.32484E-4
14-70925642-T-C p.Trp476Arg missense ADAM21 1 83214 1.20172E-5 41607 0 NA
14-70925656-A-T p.Thr480Thr synonymous ADAM21 321 83146 0.00386068 41573 7 0.00894847
14-70925661-A-G p.His482Arg missense ADAM21 32 83122 3.84976E-4 41561 0 9.24156E-4
14-70925665-G-A p.Gln483Gln synonymous ADAM21 4312 82994 0.0519556 41497 158 0.0916415
14-70925666-T-C p.Cys484Arg missense ADAM21 1 83082 1.20363E-5 41541 0 8.24457E-6
14-70925675-GAT-G p.Asp487fs frameshift ADAM21 4 82996 4.81951E-5 41498 0 NA
14-70925677-T-C p.Asp487Asp synonymous ADAM21 1 82976 1.20517E-5 41488 0 8.24729E-6
14-70925684-G-A p.Val490Met missense ADAM21 1 82828 1.20732E-5 41414 0 3.18512E-5
14-70925686-G-T p.Val490Val synonymous ADAM21 1 82772 1.20814E-5 41386 0 NA
14-70925692-C-T p.Asp492Asp synonymous ADAM21 4 82620 4.84144E-5 41310 0 1.07277E-4
14-70925703-G-A p.Cys496Tyr missense ADAM21 1 82322 1.21474E-5 41161 0 5.28541E-4
14-70925714-G-T p.Ala500Ser missense ADAM21 2 82112 2.4357E-5 41056 0 6.25E-4
14-70925718-ACTG-A p.Cys502del disruptive_inframe_deletion ADAM21 3 82028 3.65729E-5 41014 0 4.95442E-5
14-70925720-T-C p.Cys502Arg missense ADAM21 2 81962 2.44016E-5 40981 0 3.18532E-5
14-70925720-T-G p.Cys502Gly missense ADAM21 1 81962 1.22008E-5 40981 0 3.18532E-5
14-70925723-T-C p.Tyr503His missense ADAM21 1 81890 1.22115E-5 40945 0 NA
14-70925734-G-T p.Arg506Ser missense ADAM21 1 81622 1.22516E-5 40811 0 NA
14-70925739-A-G p.Asn508Ser missense ADAM21 1 81548 1.22627E-5 40774 0 3.97994E-6
14-70925757-G-C p.Cys514Ser missense ADAM21 1 81282 1.23028E-5 40641 0 NA
14-70925791-A-G p.Ala525Ala synonymous ADAM21 9 80720 1.11497E-4 40360 1 2.27994E-4
14-70925818-T-C p.Asn534Asn synonymous ADAM21 40160 65616 0.612046 32808 13478 0.747863
14-70925818-T-G p.Asn534Lys missense ADAM21 3 80180 3.74158E-5 40090 0 3.70583E-5
14-70925822-C-A p.Gln536Lys missense ADAM21 1 80282 1.24561E-5 40141 0 NA
14-70925830-C-A p.Asn538Lys missense ADAM21 1 80374 1.24418E-5 40187 0 NA
14-70925831-C-T p.Arg539Cys missense ADAM21 1 80450 1.24301E-5 40225 0 8.0679E-6
14-70925832-G-A p.Arg539His missense ADAM21 6 80514 7.45212E-5 40257 0 1.12869E-4
14-70925836-T-C p.Phe540Phe synonymous ADAM21 2 80576 2.48213E-5 40288 0 1.27665E-4
14-70925840-C-T p.His542Tyr missense ADAM21 90 80542 0.00111743 40271 0 0.0112923
14-70925854-T-A p.Asn546Lys missense ADAM21 2 81114 2.46567E-5 40557 0 8.02182E-6
14-70925856-GCA-G p.Thr548fs frameshift ADAM21 1 81096 1.23311E-5 40548 0 NA
14-70925856-G-T p.Gly547Val missense ADAM21 1 81094 1.23314E-5 40547 0 NA
14-70925863-A-C p.Thr549Thr synonymous ADAM21 2287 79506 0.0287651 39753 65 0.0560847
14-70925866-C-G p.Tyr550* stop_gained ADAM21 4 81500 4.90798E-5 40750 0 8.4219E-6
14-70925869-A-G p.Leu551Leu synonymous ADAM21 1 81596 1.22555E-5 40798 0 8.41312E-6
14-70925877-A-G p.His554Arg missense ADAM21 1 81870 1.22145E-5 40935 0 2.00077E-5
14-70925884-TG-T p.Asp557fs frameshift ADAM21 1 82122 1.2177E-5 41061 0 NA
14-70925885-G-T p.Asp557Tyr missense ADAM21 1 82156 1.2172E-5 41078 0 5.29101E-4
14-70925886-A-T p.Asp557Val missense ADAM21 1 82158 1.21717E-5 41079 0 5.29101E-4
14-70925887-T-G p.Asp557Glu missense ADAM21 1 82214 1.21634E-5 41107 0 3.18959E-5
14-70925899-G-A p.Gly561Gly synonymous ADAM21 1 82416 1.21336E-5 41208 0 2.79716E-5
14-70925908-A-G p.Gln564Gln synonymous ADAM21 1 82644 1.21001E-5 41322 0 8.32972E-6
14-70925926-C-T p.Asp570Asp synonymous ADAM21 202 82820 0.00243902 41410 0 0.00625
14-70925926-C-A p.Asp570Glu missense ADAM21 2 82934 2.41156E-5 41467 0 3.18573E-5
14-70925927-A-T p.Ile571Phe missense ADAM21 5 82980 6.02555E-5 41490 0 6.25E-4
14-70925930-C-T p.Pro572Ser missense ADAM21 66 82970 7.95468E-4 41485 0 0.00159297
14-70925952-C-T p.Thr579Ile missense ADAM21 1 83230 1.20149E-5 41615 0 3.9795E-6
14-70925965-T-C p.Thr583Thr synonymous ADAM21 1 83302 1.20045E-5 41651 0 3.97817E-6
14-70925966-C-G p.His584Asp missense ADAM21 3 83306 3.60118E-5 41653 0 5.03525E-4
14-70925967-A-AT p.Ile585fs frameshift ADAM21 2 83312 2.40061E-5 41656 0 6.37024E-5
14-70925973-A-G p.Asn586Ser missense ADAM21 1 83330 1.20005E-5 41665 0 1.19333E-5
14-70925988-G-A p.Trp591* stop_gained ADAM21 1 83362 1.19959E-5 41681 0 NA
14-70926014-A-C p.Asn600His missense ADAM21 5 83396 5.99549E-5 41698 0 1.59236E-4
14-70926016-C-T p.Asn600Asn synonymous ADAM21 1 83398 1.19907E-5 41699 0 7.95418E-6
14-70926021-C-G p.Ser602Cys missense ADAM21 1 83404 1.19898E-5 41702 0 NA
14-70926024-A-T p.Asp603Val missense ADAM21 2 83408 2.39785E-5 41704 0 3.18431E-5
14-70926024-A-G p.Asp603Gly missense ADAM21 3 83408 3.59678E-5 41704 0 1.64794E-5
14-70926033-A-C p.Glu606Ala missense ADAM21 23 83398 2.75786E-4 41699 0 8.32248E-4
14-70926034-A-G p.Glu606Glu synonymous ADAM21 1 83406 1.19895E-5 41703 0 NA
14-70926037-G-C p.Val607Val synonymous ADAM21 1 83408 1.19893E-5 41704 0 NA
14-70926043-TG-T p.Gly610fs frameshift ADAM21 1 83410 1.1989E-5 41705 0 NA
14-70926046-T-C p.Gly610Gly synonymous ADAM21 2 83408 2.39785E-5 41704 0 NA
14-70926050-G-C p.Val612Leu missense ADAM21 23 83406 2.7576E-4 41703 0 5.03525E-4
14-70926063-G-A p.Gly616Glu missense ADAM21 1 83412 1.19887E-5 41706 0 3.1839E-5
14-70926070-C-G p.Ile618Met missense ADAM21 1 83416 1.19881E-5 41708 0 NA
14-70926090-T-G p.Val625Gly missense ADAM21 4 83416 4.79524E-5 41708 1 3.97674E-6
14-70926092-AGTCT-A p.Val629fs frameshift ADAM21 2 83412 2.39774E-5 41706 0 8.239E-6
14-70926093-G-A p.Ser626Asn missense ADAM21 1 83408 1.19893E-5 41704 0 NA
14-70926093-G-C p.Ser626Thr missense ADAM21 2 83408 2.39785E-5 41704 0 5.76711E-5
14-70926095-C-T p.Leu627Leu synonymous ADAM21 2 83402 2.39802E-5 41701 0 NA
14-70926106-G-A p.Leu630Leu synonymous ADAM21 2 83400 2.39808E-5 41700 0 NA
14-70926112-T-C p.His632His synonymous ADAM21 68 83398 8.15367E-4 41699 0 0.00277017
14-70926112-T-G p.His632Gln missense ADAM21 3 83406 3.59686E-5 41703 0 3.29554E-5
14-70926113-G-A p.Val633Ile missense ADAM21 1 83410 1.1989E-5 41705 0 2.4717E-5
14-70926118-C-T p.Cys634Cys synonymous ADAM21 1 83406 1.19895E-5 41703 0 NA
14-70926135-A-G p.Asn640Ser missense ADAM21 37 83392 4.43688E-4 41696 0 1.31229E-4
14-70926144-G-A p.Gly643Glu missense ADAM21 1 83382 1.1993E-5 41691 0 1.07377E-4
14-70926147-T-G p.Ile644Ser missense ADAM21 1 83388 1.19921E-5 41694 0 8.23927E-6
14-70926151-CA-C p.Asn646fs frameshift ADAM21 1 83382 1.1993E-5 41691 0 NA
14-70926153-A-AAG p.Asn646fs frameshift ADAM21 1 83380 1.19933E-5 41690 0 NA
14-70926156-A-G p.Asn647Ser missense ADAM21 1 83384 1.19927E-5 41692 0 6.37105E-5
14-70926168-G-T p.Cys651Phe missense ADAM21 1 83362 1.19959E-5 41681 0 NA
14-70926169-C-G p.Cys651Trp missense ADAM21 1 83360 1.19962E-5 41680 0 NA
14-70926178-C-T p.Gly654Gly synonymous ADAM21 2 83330 2.4001E-5 41665 0 4.94576E-5
14-70926181-T-G p.Tyr655* stop_gained ADAM21 3 83326 3.60032E-5 41663 0 7.41889E-5
14-70926193-A-G p.Pro659Pro synonymous ADAM21 2 83314 2.40056E-5 41657 0 1.59148E-5
14-70926195-C-T p.Pro660Leu missense ADAM21 5 83318 6.0011E-5 41659 0 3.1835E-5
14-70926201-G-A p.Cys662Tyr missense ADAM21 1 83314 1.20028E-5 41657 0 NA
14-70926208-C-G p.His664Gln missense ADAM21 3 83304 3.60127E-5 41652 0 NA
14-70926216-A-G p.Tyr667Cys missense ADAM21 1 83302 1.20045E-5 41651 0 NA
14-70926227-A-G p.Ile671Val missense ADAM21 31 83268 3.72292E-4 41634 0 2.30977E-4
14-70926249-CAA-C p.Lys679fs frameshift ADAM21 2 83226 2.4031E-5 41613 0 3.18431E-5
14-70926257-G-A p.Gly681Arg missense ADAM21 4 83186 4.8085E-5 41593 0 5.03525E-4
14-70926260-G-GT p.Leu684fs frameshift ADAM21 7 83174 8.41609E-5 41587 0 2.11118E-4
14-70926262-T-G p.Val682Val synonymous ADAM21 2 83164 2.40489E-5 41582 0 NA
14-70926270-C-T p.Pro685Leu missense ADAM21 6 83110 7.21935E-5 41555 0 0.00100705
14-70926271-G-A p.Pro685Pro synonymous ADAM21 16 83110 1.92516E-4 41555 0 8.76347E-5
14-70926285-CTTCT-C p.Ser691fs frameshift ADAM21 1 83080 1.20366E-5 41540 0 NA
14-70926288-CTTT-C p.Leu692del disruptive_inframe_deletion ADAM21 4 83066 4.81545E-5 41533 0 6.36902E-5
14-70926290-T-G p.Leu692Val missense ADAM21 1 83060 1.20395E-5 41530 0 1.19556E-5
14-70926291-T-G p.Leu692Trp missense ADAM21 3 83060 3.61185E-5 41530 0 NA
14-70926305-T-C p.Phe697Leu missense ADAM21 12 83018 1.44547E-4 41509 0 1.15704E-4
14-70926308-CT-C p.Leu698fs frameshift ADAM21 1 83010 1.20467E-5 41505 0 NA
14-70926310-G-C p.Leu698Leu synonymous ADAM21 1 82984 1.20505E-5 41492 0 8.26911E-6
14-70926319-C-T p.Val701Val synonymous ADAM21 17 82964 2.04908E-4 41482 0 4.4586E-4
14-70926320-G-A p.Gly702Arg missense ADAM21 2 82954 2.41097E-5 41477 0 3.18471E-5
14-70926330-T-C p.Met705Thr missense ADAM21 44 82970 5.30312E-4 41485 0 5.82058E-4
14-70926332-T-C p.Tyr706His missense ADAM21 4 82966 4.82125E-5 41483 0 3.18951E-5
14-70926338-C-T p.Arg708* stop_gained ADAM21 6 82974 7.23118E-5 41487 0 1.2432E-4
14-70926347-T-G p.Ser711Ala missense ADAM21 1 82946 1.2056E-5 41473 0 NA
14-70926357-A-G p.Lys714Arg missense ADAM21 2 82834 2.41447E-5 41417 0 8.30041E-6
14-70926364-T-G p.Thr716Thr synonymous ADAM21 2 82796 2.41558E-5 41398 0 8.31186E-6
14-70926365-A-C p.Lys717Gln missense ADAM21 3 82786 3.6238E-5 41393 0 1.59586E-5
14-70926368-G-C p.Ala718Pro missense ADAM21 1 82730 1.20875E-5 41365 0 2.49513E-5
14-70926372-A-T p.His719Leu missense ADAM21 1 82662 1.20975E-5 41331 0 9.99967E-5
14-70926381-G-T p.Gly722Val missense ADAM21 1 82474 1.2125E-5 41237 0 NA
14-70926385-A-G p.Ter723Ter stop_retained ADAM21 2 82344 2.42884E-5 41172 0 NA